Proceedings of the National Academy of Sciences of the United States of America

Displaying 51 - 88 of 88
Chang, Y.-J., Jenny, L. A., Li, Y.-S., Cui, X., Kong, Y., Li, Y., Sparrow, J. R., & Tsang, S. H. (2023). CRISPR editing demonstrates rs10490924 raised oxidative stress in iPSC-derived retinal cells from patients with ARMS2/HTRA1 -related AMD. Proceedings of the National Academy of Sciences, 120(19). https://doi.org/10.1073/pnas.2215005120
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Cosper, P. F., Hrycyniak, L. C. F., Paracha, M., Lee, D. L., Wan, J., Jones, K., Bice, S. A., Nickel, K., Mallick, S., Taylor, A. M., Kimple, R. J., Lambert, P. F., & Weaver, B. A. (2023). HPV16 E6 induces chromosomal instability due to polar chromosomes caused by E6AP-dependent degradation of the mitotic kinesin CENP-E. Proceedings of the National Academy of Sciences, 120(14). https://doi.org/10.1073/pnas.2216700120
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Fritschi, C. J., Anang, S., Gong, Z., Mohammadi, M., Richard, J., Bourassa, C., Severino, K. T., Richter, H., Yang, D., Chen, H.-C., Chiu, T.-J., Seaman, M. S., Madani, N., Abrams, C., Finzi, A., Hendrickson, W. A., Sodroski, J. G., & Smith, A. B. (2023). Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity. Proceedings of the National Academy of Sciences, 120(13). https://doi.org/10.1073/pnas.2222073120
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Vlasevska, S., Garcia-Ibanez, L., Duval, R., Holmes, A. B., Jahan, R., Cai, B., Kim, A., Mo, T., Basso, K., Soni, R. K., Bhagat, G., Dalla-Favera, R., & Pasqualucci, L. (2023). KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells. Proceedings of the National Academy of Sciences, 120(11). https://doi.org/10.1073/pnas.2218330120
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Ford, L., Asok, A., Tripp, A. D., Parro, C., Fitzpatrick, M., de Solis, C. A., Chen, P.-T. Y., Shafiian, N., Fioriti, L., Soni, R. K., & Kandel, E. R. (2023). CPEB3 low-complexity motif regulates local protein synthesis via protein–protein interactions in neuronal ribonucleoprotein granules. Proceedings of the National Academy of Sciences, 120(6). https://doi.org/10.1073/pnas.2114747120
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Dahal, P., Rauhala, O. J., Khodagholy, D., & Gelinas, J. N. (2023). Hippocampal–cortical coupling differentiates long-term memory processes. Proceedings of the National Academy of Sciences, 120(7). https://doi.org/10.1073/pnas.2207909120
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Jensen, A. M. G., Kitago, Y., Fazeli, E., Vægter, C. B., Small, S. A., Petsko, G. A., & Andersen, O. M. (2023). Dimerization of the Alzheimer’s disease pathogenic receptor SORLA regulates its association with retromer. Proceedings of the National Academy of Sciences, 120(4). https://doi.org/10.1073/pnas.2212180120
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He, H., Ahsan, A., Bera, R., McLain, N., Faulkner, R., Ramachandran, K. V., Margolis, S. S., & Cline, H. T. (2023). Neuronal membrane proteasomes regulate neuronal circuit activity in vivo and are required for learning-induced behavioral plasticity. Proceedings of the National Academy of Sciences, 120(3). https://doi.org/10.1073/pnas.2216537120
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Mannes, P. Z., Barnes, C. E., Biermann, J., Latoche, J. D., Day, K. E., Zhu, Q., Tabary, M., Xiong, Z., Nedrow, J. R., Izar, B., Anderson, C. J., Villanueva, F. S., Lee, J. S., & Tavakoli, S. (2023). Molecular imaging of chemokine-like receptor 1 (CMKLR1) in experimental acute lung injury. Proceedings of the National Academy of Sciences, 120(3). https://doi.org/10.1073/pnas.2216458120
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Abramov, A., Xue, Y., Zakharchenko, A., Kurade, M., Soni, R. K., Levy, R. J., & Ferrari, G. (2022). Bioprosthetic heart valve structural degeneration associated with metabolic syndrome: Mitigation with polyoxazoline modification. Proceedings of the National Academy of Sciences, 120(1). https://doi.org/10.1073/pnas.2219054120
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Gong, Z., Wang, W., El Omari, K., Lebedev, A. A., Clarke, O. B., & Hendrickson, W. A. (2022). Crystal structure of LGR ligand α2/β5 from Caenorhabditis elegans with implications for the evolution of glycoprotein hormones. Proceedings of the National Academy of Sciences, 120(1). https://doi.org/10.1073/pnas.2218630120
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Du, Z., Wang, L., Shan, S., Lam, D., Tsang, T. K., Xiao, J., Gao, H., Yang, B., Ali, S. T., Pei, S., Fung, I. C.-H., Lau, E. H. Y., Liao, Q., Wu, P., Meyers, L. A., Leung, G. M., & Cowling, B. J. (2022). Pandemic fatigue impedes mitigation of COVID-19 in Hong Kong. Proceedings of the National Academy of Sciences, 119(48). https://doi.org/10.1073/pnas.2213313119
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Shanahan, M. J., Cole, S. W., Ravi, S., Chumbley, J., Xu, W., Potente, C., Levitt, B., Bodelet, J., Aiello, A., Gaydosh, L., & Harris, K. M. (2022). Socioeconomic inequalities in molecular risk for chronic diseases observed in young adulthood. Proceedings of the National Academy of Sciences, 119(43). https://doi.org/10.1073/pnas.2103088119
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Boni, N., Shapiro, L., Honig, B., Wu, Y., & Rubinstein, R. (2022). On the formation of ordered protein assemblies in cell–cell interfaces. Proceedings of the National Academy of Sciences, 119(34). https://doi.org/10.1073/pnas.2206175119
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Li, R.-C., Molday, L. L., Lin, C.-C., Ren, X., Fleischmann, A., Molday, R. S., & Yau, K.-W. (2022). Low signaling efficiency from receptor to effector in olfactory transduction: A quantified ligand-triggered GPCR pathway. Proceedings of the National Academy of Sciences, 119(32). https://doi.org/10.1073/pnas.2121225119
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Xu, P., Shimomura, K., Lee, C., Gao, X., Simpson, E. H., Huang, G., Joseph, C. M., Kumar, V., Ge, W.-P., Pawlowski, K. S., Frye, M. D., Kourrich, S., Kandel, E. R., & Takahashi, J. S. (2022). A missense mutation in Kcnc3 causes hippocampal learning deficits in mice. Proceedings of the National Academy of Sciences, 119(31). https://doi.org/10.1073/pnas.2204901119
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Mihaila, T. S., Bäte, C., Ostersehlt, L. M., Pape, J. K., Keller-Findeisen, J., Sahl, S. J., & Hell, S. W. (2022). Enhanced incorporation of subnanometer tags into cellular proteins for fluorescence nanoscopy via optimized genetic code expansion. Proceedings of the National Academy of Sciences, 119(29). https://doi.org/10.1073/pnas.2201861119
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Pérez-Torres, E. J., Utkina-Sosunova, I., Mishra, V., Barbuti, P., De Planell-Saguer, M., Dermentzaki, G., Geiger, H., Basile, A. O., Robine, N., Fagegaltier, D., Politi, K. A., Rinchetti, P., Jackson-Lewis, V., Harms, M., Phatnani, H., Lotti, F., Przedborski, S., Phatnani, H., … Traynor, B. J. (2022). Retromer dysfunction in amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences, 119(26). https://doi.org/10.1073/pnas.2118755119
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Feng, S., & Mann, R. S. (2022). SpyChIP identifies cell type-specific transcription factor occupancy from complex tissues. Proceedings of the National Academy of Sciences, 119(25). https://doi.org/10.1073/pnas.2122900119
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Ribeiro, A., Gabriel, R., Garcia, B., Cuccio, C., Aqeel, W., Moreno, A., Landeen, C., Hurley, A., Kavey, N., & Pfaff, D. (2022). Temporal relations between peripheral and central arousals in good and poor sleepers. Proceedings of the National Academy of Sciences, 119(25). https://doi.org/10.1073/pnas.2201143119
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Eltobgy, M. M., Zani, A., Kenney, A. D., Estfanous, S., Kim, E., Badr, A., Carafice, C., Daily, K., Whitham, O., Pietrzak, M., Webb, A., Kawahara, J., Eddy, A. C., Denz, P., Lu, M., KC, M., Peeples, M. E., Li, J., Zhu, J., … Amer, A. O. (2022). Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis. Proceedings of the National Academy of Sciences, 119(21). https://doi.org/10.1073/pnas.2202012119
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Hoffman, B. U., Baba, Y., Lee, S. A., Tong, C.-K., Konofagou, E. E., & Lumpkin, E. A. (2022). Focused ultrasound excites action potentials in mammalian peripheral neurons in part through the mechanically gated ion channel PIEZO2. Proceedings of the National Academy of Sciences, 119(21). https://doi.org/10.1073/pnas.2115821119
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Sun, L., Tong, C.-K., Morgenstern, T. J., Zhou, H., Yang, G., & Colecraft, H. M. (2022). Targeted ubiquitination of sensory neuron calcium channels reduces the development of neuropathic pain. Proceedings of the National Academy of Sciences, 119(20). https://doi.org/10.1073/pnas.2118129119
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Vahabikashi, A., Sivagurunathan, S., Nicdao, F. A. S., Han, Y. L., Park, C. Y., Kittisopikul, M., Wong, X., Tran, J. R., Gundersen, G. G., Reddy, K. L., Luxton, G. W. G., Guo, M., Fredberg, J. J., Zheng, Y., Adam, S. A., & Goldman, R. D. (2022). Nuclear lamin isoforms differentially contribute to LINC complex-dependent nucleocytoskeletal coupling and whole-cell mechanics. Proceedings of the National Academy of Sciences, 119(17). https://doi.org/10.1073/pnas.2121816119
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Cramer, E. Y., Ray, E. L., Lopez, V. K., Bracher, J., Brennen, A., Castro Rivadeneira, A. J., Gerding, A., Gneiting, T., House, K. H., Huang, Y., Jayawardena, D., Kanji, A. H., Khandelwal, A., Le, K., Mühlemann, A., Niemi, J., Shah, A., Stark, A., Wang, Y., … Reich, N. G. (2022). Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States. Proceedings of the National Academy of Sciences, 119(15). https://doi.org/10.1073/pnas.2113561119
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Postigo-Fernandez, J., Firdessa-Fite, R., & Creusot, R. J. (2022). Preclinical evaluation of a precision medicine approach to DNA vaccination in type 1 diabetes. Proceedings of the National Academy of Sciences, 119(15). https://doi.org/10.1073/pnas.2110987119
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Wang, Y., Shilagardi, K., Hsu, T., Odinammadu, K. O., Maruyama, T., Wu, W., Lin, C.-S., Damoci, C. B., Spear, E. D., Shin, J.-Y., Hsu, W., Michaelis, S., & Worman, H. J. (2022). Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice. Proceedings of the National Academy of Sciences, 119(9). https://doi.org/10.1073/pnas.2118695119
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Cavassim, M. I. A., Baker, Z., Hoge, C., Schierup, M. H., Schumer, M., & Przeworski, M. (2022). PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2. Proceedings of the National Academy of Sciences, 119(9). https://doi.org/10.1073/pnas.2114401119
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Zakharchenko, A., Xue, Y., Keeney, S., Rock, C. A., Alferiev, I. S., Stachelek, S. J., Takano, H., Thomas, T., Nagaswami, C., Krieger, A. M., Chorny, M., Ferrari, G., & Levy, R. J. (2022). Poly-2-methyl-2-oxazoline–modified bioprosthetic heart valve leaflets have enhanced biocompatibility and resist structural degeneration. Proceedings of the National Academy of Sciences, 119(6). https://doi.org/10.1073/pnas.2120694119
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Lieu, Y. K., Liu, Z., Ali, A. M., Wei, X., Penson, A., Zhang, J., An, X., Rabadan, R., Raza, A., Manley, J. L., & Mukherjee, S. (2021). SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes. Proceedings of the National Academy of Sciences, 119(1). https://doi.org/10.1073/pnas.2111703119
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Halvorsen, M., Gould, L., Wang, X., Grant, G., Moya, R., Rabin, R., Ackerman, M. J., Tester, D. J., Lin, P. T., Pappas, J. G., Maurano, M. T., Goldstein, D. B., Tsien, R. W., & Devinsky, O. (2021). De novo mutations in childhood cases of sudden unexplained death that disrupt intracellular Ca 2+ regulation. Proceedings of the National Academy of Sciences, 118(52). https://doi.org/10.1073/pnas.2115140118
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Park, J., Zuo, H., Frangaj, A., Fu, Z., Yen, L. Y., Zhang, Z., Mosyak, L., Slavkovich, V. N., Liu, J., Ray, K. M., Cao, B., Vallese, F., Geng, Y., Chen, S., Grassucci, R., Dandey, V. P., Tan, Y. Z., Eng, E., Lee, Y., … Fan, Q. R. (2021). Symmetric activation and modulation of the human calcium-sensing receptor. Proceedings of the National Academy of Sciences, 118(51). https://doi.org/10.1073/pnas.2115849118
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Zoghbi, A. W., Dhindsa, R. S., Goldberg, T. E., Mehralizade, A., Motelow, J. E., Wang, X., Alkelai, A., Harms, M. B., Lieberman, J. A., Markx, S., & Goldstein, D. B. (2021). High-impact rare genetic variants in severe schizophrenia. Proceedings of the National Academy of Sciences, 118(51). https://doi.org/10.1073/pnas.2112560118
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Adler, A., Lai, C. S. W., Yang, G., Geron, E., Bai, Y., & Gan, W.-B. (2021). Sleep promotes the formation of dendritic filopodia and spines near learning-inactive existing spines. Proceedings of the National Academy of Sciences, 118(50). https://doi.org/10.1073/pnas.2114856118
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Ke, R., Zitzmann, C., Ho, D. D., Ribeiro, R. M., & Perelson, A. S. (2021). In vivo kinetics of SARS-CoV-2 infection and its relationship with a person’s infectiousness. Proceedings of the National Academy of Sciences, 118(49). https://doi.org/10.1073/pnas.2111477118
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