Bailey, J. A., Kong, M. D., Piamjitchol, C., Hou, B., Exinor, A., Nayak, A., Heaps, N., Demirkol, A., & Tsang, S. H. (2025). X-Linked CGD Chorioretinitis in Two Young Girls. Biomedicines, 13(2), 323. https://doi.org/10.3390/biomedicines13020323

Yuan, F., Yang, J., Ma, F., Hu, Z., Malik, V., Zang, R., Li, D., Shi, X., Huang, X., Zhou, H., & Wang, J. (2025). Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57165-2

Ma, L., Pang, Z., Zhang, H., Yang, X., Zheng, S., Chen, Y., Ding, W., Han, Q., Zhang, X., Cao, L., Fei, T., Wang, Q., Gao, D., He, A., Hu, K.-B., Li, X., & Sheng, R. (2025). Clear cell renal carcinoma essentially requires CDKL3 for oncogenesis. Proceedings of the National Academy of Sciences, 122(7). https://doi.org/10.1073/pnas.2415244122

Xin, X., Chen, C., Xu, X., Lv, S., Sun, Q., An, Z., Chen, Y., Xiong, Z., Hu, Y., & Feng, Q. (2025). Caffeine ameliorates metabolic-associated steatohepatitis by rescuing hepatic Dusp9. Redox Biology, 80, 103499. https://doi.org/10.1016/j.redox.2025.103499

Furuhashi, K., Kakiuchi, M., Ueda, R., Oda, H., Ummarino, S., Ebralidze, A. K., Bassal, M. A., Meng, C., Sato, T., Lyu, J., Han, M., Maruyama, S., Watanabe, Y., Sawa, Y., Kato, D., Wake, H., Reizis, B., Frangos, J. A., Owens, D. M., … Fujisaki, J. (2025). Bone marrow niches orchestrate stem-cell hierarchy and immune tolerance. Nature. https://doi.org/10.1038/s41586-024-08352-6

Xu, S., & Egli, D. (2024). Genome organization and stability in mammalian pre-implantation development. DNA Repair, 144, 103780. https://doi.org/10.1016/j.dnarep.2024.103780

Kumar, M., Jiang, S., Lorman, D., David, L., Soni, R., Kissner, M., Yang, M., & Myeku, N. (2024). The role of immunoproteasomes in modulating neuro‐inflammation in Alzheimer’s Disease. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.086577

Sheikh, M. A., Afandi, F. H., Iannello, G., Corneo, B., Emerald, B. S., & Ansari, S. A. (2024). CRISPR-Cas9 Mediated Gene Deletion in Human Pluripotent Stem Cells Cultured Under Feeder-Free Conditions. Journal of Visualized Experiments, 213. https://doi.org/10.3791/67296

Mushtaq, M., Liaño-Pons, J., Wang, J., Alzrigat, M., Yuan, Y., Ruiz-Pérez, M. V., Chen, Y., Kashuba, E., Haglund de Flon, F., Brodin, B., & Arsenian-Henriksson, M. (2024). EZH2 inhibition sensitizes retinoic acid-driven senescence in synovial sarcoma. Cell Death & Disease, 15(11). https://doi.org/10.1038/s41419-024-07176-6

Leifer, V. P., Fang, F., Song, L., Kim, J., Papanikolaou, J. F., Smeeton, J., & Thomopoulos, S. (2024). Single-cell RNA-sequencing analysis of immune and mesenchymal cell crosstalk in the developing enthesis. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-77958-7

Gao, V. R., Yang, R., Das, A., Luo, R., Luo, H., McNally, D. R., Karagiannidis, I., Rivas, M. A., Wang, Z.-M., Barisic, D., Karbalayghareh, A., Wong, W., Zhan, Y. A., Chin, C. R., Noble, W. S., Bilmes, J. A., Apostolou, E., Kharas, M. G., Béguelin, W., … Leslie, C. S. (2024). ChromaFold predicts the 3D contact map from single-cell chromatin accessibility. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-53628-0

Chen, J., Dalerba, P., Terry, M. B., & Yang, W. (2024). Global obesity epidemic and rising incidence of early-onset cancers. Journal of Global Health, 14. https://doi.org/10.7189/jogh.14.04205

Edwards, M. M., Wang, N., Sagi, I., Kinreich, S., Benvenisty, N., Gerhardt, J., Egli, D., & Koren, A. (2024). Parent-of-origin-specific DNA replication timing is confined to large imprinted regions. Cell Reports, 43(9), 114700. https://doi.org/10.1016/j.celrep.2024.114700

Ho, J., Puoplo, N., Pokharel, N., Hirdaramani, A., Hanyaloglu, A. C., & Cheng, C.-W. (2024). Nutrigenomic underpinnings of intestinal stem cells in inflammatory bowel disease and colorectal cancer development. Frontiers in Genetics, 15. https://doi.org/10.3389/fgene.2024.1349717

Chen, Y., Su, Y., Cao, X., Siavelis, I., Leo, I. R., Zeng, J., Tsagkozis, P., Hesla, A. C., Papakonstantinou, A., Liu, X., Huang, W., Zhao, B., Haglund, C., Ehnman, M., Johansson, H., Lin, Y., Lehtiö, J., Zhang, Y., Larsson, O., … de Flon, F. H. (2024). Molecular Profiling Defines Three Subtypes of Synovial Sarcoma. Advanced Science, 11(41). Portico. https://doi.org/10.1002/advs.202404510

Imada, S., Khawaled, S., Shin, H., Meckelmann, S. W., Whittaker, C. A., Corrêa, R. O., Alquati, C., Lu, Y., Tie, G., Pradhan, D., Calibasi-Kocal, G., Nascentes Melo, L. M., Allies, G., Rösler, J., Wittenhofer, P., Krystkiewicz, J., Schmitz, O. J., Roper, J., Vinolo, M. A. R., … Yilmaz, Ö. H. (2024). Short-term post-fast refeeding enhances intestinal stemness via polyamines. Nature, 633(8031), 895–904. https://doi.org/10.1038/s41586-024-07840-z

Bashore, A. C., Xue, C., Kim, E., Yan, H., Zhu, L. Y., Pan, H., Kissner, M., Ross, L. S., Zhang, H., Li, M., & Reilly, M. P. (2024). Monocyte Single-Cell Multimodal Profiling in Cardiovascular Disease Risk States. Circulation Research, 135(6), 685–700. https://doi.org/10.1161/circresaha.124.324457

Jang, S., Gumnit, E., & Wichterle, H. (2024). A human-specific progenitor sub-domain extends neurogenesis and increases motor neuron production. Nature Neuroscience. https://doi.org/10.1038/s41593-024-01739-8

Zaydon, Y. A., & Tsang, S. H. (2024). The ABCs of Stargardt disease: the latest advances in precision medicine. Cell & Bioscience, 14(1). https://doi.org/10.1186/s13578-024-01272-y

Guilz, N. C., Ahn, Y.-O., Fatima, H., Pedroza, L. A., Seo, S., Soni, R. K., Wang, N., Egli, D., & Mace, E. M. (2024). Replication Stress in Activated Human NK Cells Induces Sensitivity to Apoptosis. The Journal of Immunology, 213(1), 40–51. https://doi.org/10.4049/jimmunol.2300843

Piszker, W., & Simunovic, M. (2024). The fusion of physics and biology in early mammalian embryogenesis. Current Topics in Developmental Biology, 31–64. https://doi.org/10.1016/bs.ctdb.2024.05.001

Xu, S., Wang, N., Zuccaro, M. V., Gerhardt, J., Iyyappan, R., Scatolin, G. N., Jiang, Z., Baslan, T., Koren, A., & Egli, D. (2024). DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-49565-7

Malagola, E., Vasciaveo, A., Ochiai, Y., Kim, W., Zheng, B., Zanella, L., Wang, A. L. E., Middelhoff, M., Nienhüser, H., Deng, L., Wu, F., Waterbury, Q. T., Belin, B., LaBella, J., Zamechek, L. B., Wong, M. H., Li, L., Guha, C., Cheng, C.-W., … Wang, T. C. (2024). Isthmus progenitor cells contribute to homeostatic cellular turnover and support regeneration following intestinal injury. Cell, 187(12), 3056-3071.e17. https://doi.org/10.1016/j.cell.2024.05.004

Tanaka, J., Miura, A., Shimamura, Y., Hwang, Y., Shimizu, D., Kondo, Y., Sawada, A., Sarmah, H., Ninish, Z., Mishima, K., & Mori, M. (2024). Generation of salivary glands derived from pluripotent stem cells via conditional blastocyst complementation. Cell Reports, 43(6), 114340. https://doi.org/10.1016/j.celrep.2024.114340

Dunbar, A. J., Bowman, R. L., Park, Y. C., O’Connor, K., Izzo, F., Myers, R. M., Karzai, A., Zaroogian, Z., Kim, W. J., Fernández-Maestre, I., Waarts, M. R., Nazir, A., Xiao, W., Codilupi, T., Brodsky, M., Farina, M., Cai, L., Cai, S. F., Wang, B., … Levine, R. L. (2024). Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms. Cancer Discovery, 14(5), 737–751. https://doi.org/10.1158/2159-8290.cd-22-0952

Gao, L., Lee, H., Goodman, J. H., & Ding, L. (2024). Hematopoietic stem cell niche generation and maintenance are distinguishable by an epitranscriptomic program. Cell, 187(11), 2801-2816.e17. https://doi.org/10.1016/j.cell.2024.03.032

Gao, L., & Ding, L. (2024). METTL3: Melting the tumor microenvironment for improved immunotherapy. Cell Chemical Biology, 31(4), 629–631. https://doi.org/10.1016/j.chembiol.2024.03.005

Xu, J. J., & Viny, A. D. (2024). Chromatin organization in myelodysplastic syndrome. Experimental Hematology, 134, 104216. https://doi.org/10.1016/j.exphem.2024.104216

Throesch, B. T., bin Imtiaz, M. K., Muñoz-Castañeda, R., Sakurai, M., Hartzell, A. L., James, K. N., Rodriguez, A. R., Martin, G., Lippi, G., Kupriyanov, S., Wu, Z., Osten, P., Izpisua Belmonte, J. C., Wu, J., & Baldwin, K. K. (2024). Functional sensory circuits built from neurons of two species. Cell, 187(9), 2143-2157.e15. https://doi.org/10.1016/j.cell.2024.03.042

Collins, A., Swann, J. W., Proven, M. A., Patel, C. M., Mitchell, C. A., Kasbekar, M., Dellorusso, P. V., & Passegué, E. (2024). Maternal inflammation regulates fetal emergency myelopoiesis. Cell, 187(6), 1402-1421.e21. https://doi.org/10.1016/j.cell.2024.02.002

Bashore, A. C., Yan, H., Xue, C., Zhu, L. Y., Kim, E., Mawson, T., Coronel, J., Chung, A., Sachs, N., Ho, S., Ross, L. S., Kissner, M., Passegué, E., Bauer, R. C., Maegdefessel, L., Li, M., & Reilly, M. P. (2024). High-Dimensional Single-Cell Multimodal Landscape of Human Carotid Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 44(4), 930–945. https://doi.org/10.1161/atvbaha.123.320524

Chen, J., Terry, M. B., Dalerba, P., Hur, C., Hu, J., & Yang, W. (2024). Environmental drivers of the rising incidence of early‐onset colorectal cancer in the United States. International Journal of Cancer, 154(11), 1930–1939. Portico. https://doi.org/10.1002/ijc.34887

Cherkaoui, I., Du, Q., Egli, D., Misra, S., & Rutter, G. A. (2024). Optimized Protocol for Generating Functional Pancreatic Insulin-secreting Cells from Human Pluripotent Stem Cells. Journal of Visualized Experiments, 204. https://doi.org/10.3791/65530

Georgiou, M., Fujinami, K., Robson, A. G., Fujinami-Yokokawa, Y., Shakarchi, A. F., Ji, M. H., Uwaydat, S. H., Kim, A., Kolesnikova, M., Arno, G., Pontikos, N., Mahroo, O. A., Tsang, S. H., Webster, A. R., & Michaelides, M. (2024). RBP3-Retinopathy—Inherited High Myopia and Retinal Dystrophy: Genetic Characterization, Natural History, and Deep Phenotyping. American Journal of Ophthalmology, 258, 119–129. https://doi.org/10.1016/j.ajo.2023.09.025

Edwards, M. M., Wang, N., Massey, D. J., Bhatele, S., Egli, D., & Koren, A. (2024). Incomplete reprogramming of DNA replication timing in induced pluripotent stem cells. Cell Reports, 43(1), 113664. https://doi.org/10.1016/j.celrep.2023.113664

Zhang, Y., Sui, L., Du, Q., Haataja, L., Yin, Y., Viola, R., Xu, S., Nielsson, C. U., Leibel, R. L., Barbetti, F., Arvan, P., & Egli, D. (2024). Permanent neonatal diabetes-causing insulin mutations have dominant negative effects on beta cell identity. Molecular Metabolism, 80, 101879. https://doi.org/10.1016/j.molmet.2024.101879

Kubota, Y., & Viny, A. D. (2024). Germline predisposition for clonal hematopoiesis. Seminars in Hematology, 61(1), 61–67. https://doi.org/10.1053/j.seminhematol.2024.01.007

Laznovsky, J., Kavkova, M., Helena Reis, A., Robovska-Havelkova, P., Maia, L. A., Krivanek, J., Zikmund, T., Kaiser, J., Buchtova, M., & Harnos, J. (2024). Unveiling vertebrate development dynamics in frog Xenopus laevis using micro-CT imaging. GigaScience, 13. https://doi.org/10.1093/gigascience/giae037

Anderson, T., Mo, J., Gagarin, E., Sherwood, D., Blumenkrantz, M., Mao, E., Leon, G., Levitz, H., Chen, H.-J., Tseng, K.-C., Fabian, P., Crump, J. G., & Smeeton, J. (2023). Ligament injury in adult zebrafish triggers ECM remodeling and cell dedifferentiation for scar-free regeneration. Npj Regenerative Medicine, 8(1). https://doi.org/10.1038/s41536-023-00329-9

Martino, J., Liu, Q., Vukojevic, K., Ke, J., Lim, T. Y., Khan, A., Gupta, Y., Perez, A., Yan, Z., Milo Rasouly, H., Vena, N., Lippa, N., Giordano, J. L., Saraga, M., Saraga-Babic, M., Westland, R., Bodria, M., Piaggio, G., Bendapudi, P. K., … Sanna-Cherchi, S. (2023). Mouse and human studies support DSTYK loss of function as a low-penetrance and variable expressivity risk factor for congenital urinary tract anomalies. Genetics in Medicine, 25(12), 100983. https://doi.org/10.1016/j.gim.2023.100983

Wang, N.-K., Liu, P.-K., Kong, Y., Tseng, Y.-J., Jenny, L. A., Nolan, N. D., Chen, N., Wang, H.-H., Hsu, C. W., Huang, W.-C., Sparrow, J. R., Lin, C.-S., & Tsang, S. H. (2023). Spatiotemporal control of genome engineering in cone photoreceptors. Cell & Bioscience, 13(1). https://doi.org/10.1186/s13578-023-01033-3

Shah, R., Shah, V. K., Emin, M., Gao, S., Sampogna, R. V., Aggarwal, B., Chang, A., St-Onge, M.-P., Malik, V., Wang, J., Wei, Y., & Jelic, S. (2023). Mild sleep restriction increases endothelial oxidative stress in female persons. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-42758-y

Jentzsch, M. C., Tsang, S. H., & Koch, S. F. (2023). A New Preclinical Model of Retinitis Pigmentosa Due to Pde6g Deficiency. Ophthalmology Science, 3(4), 100332. https://doi.org/10.1016/j.xops.2023.100332

Herb, B. R., Glover, H. J., Bhaduri, A., Colantuoni, C., Bale, T. L., Siletti, K., Hodge, R., Lein, E., Kriegstein, A. R., Doege, C. A., & Ament, S. A. (2023). Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus. Science Advances, 9(45). https://doi.org/10.1126/sciadv.adf6251

Glover, H. J., Holliday, H., Shparberg, R. A., Winkler, D., Day, M., & Morris, M. B. (2023). Signalling pathway crosstalk stimulated by L-proline drives mouse embryonic stem cells to primitive-ectoderm-like cells. Development, 150(20). https://doi.org/10.1242/dev.201704

Kasbekar, M., Mitchell, C. A., Proven, M. A., & Passegué, E. (2023). Hematopoietic stem cells through the ages: A lifetime of adaptation to organismal demands. Cell Stem Cell, 30(11), 1403–1420. https://doi.org/10.1016/j.stem.2023.09.013

Bickle, J. G., Li, Y., Millette, A., Dixon, R., Wu, S., Arias, E. C., Luna, V. M., & Anacker, C. (2024). 5-HT1A Receptors on Dentate Gyrus Granule Cells Confer Stress Resilience. Biological Psychiatry, 95(8), 800–809. https://doi.org/10.1016/j.biopsych.2023.10.007

Wang, N., Xu, S., & Egli, D. (2023). Replication stress in mammalian embryo development, differentiation, and reprogramming. Trends in Cell Biology, 33(10), 872–886. https://doi.org/10.1016/j.tcb.2023.03.015

Ruscitto, A., Chen, P., Tosa, I., Wang, Z., Zhou, G., Safina, I., Wei, R., Morel, M. M., Koch, A., Forman, M., Reeve, G., Lecholop, M. K., Wilson, M., Bonthius, D., Chen, M., Ono, M., Wang, T. C., Yao, H., & Embree, M. C. (2023). Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity. Cell Stem Cell, 30(9), 1179-1198.e7. https://doi.org/10.1016/j.stem.2023.08.004

Oh, J. K., Levi, S. R., de Carvalho, J. R. L., Abdelhakim, A. H., Hirano, M., Maumenee, I. H., & Tsang, S. H. (2023). Venous Tortuosity in COL4A2-Associated Gould Syndrome. Ophthalmic Surgery, Lasers and Imaging Retina, 54(9), 536–539. https://doi.org/10.3928/23258160-20230811-01