Mosharov, E. V., Rosenberg, A. M., Monzel, A. S., Osto, C. A., Stiles, L., Rosoklija, G. B., Dwork, A. J., Bindra, S., Junker, A., Zhang, Y., Fujita, M., Mariani, M. B., Bakalian, M., Sulzer, D., De Jager, P. L., Menon, V., Shirihai, O. S., Mann, J. J., Underwood, M. D., … Picard, M. (2025). A human brain map of mitochondrial respiratory capacity and diversity. Nature. https://doi.org/10.1038/s41586-025-08740-6

Bagger, S. M., Schihada, H., Walser, A. L. S., Drzazga, A. K., Grätz, L., Palmisano, T., Kuhn, C. K., Mavri, M., Mølleskov-Jensen, A.-S., Tall, G. G., Schöneberg, T., Mathiasen, S. J., Javitch, J. A., Schulte, G., Spiess, K., & Rosenkilde, M. M. (2025). Complex G-protein signaling of the adhesion GPCR, ADGRA3. Journal of Biological Chemistry, 108441. https://doi.org/10.1016/j.jbc.2025.108441

García Barberá, F., Picech, F., Cecenarro, L., Mezger, G. F., Faure, E., Zlocowski, N., Calafat, P., De Battista, J. C., Mukdsi, J. H., Sosa, L. del V., & Petiti, J. P. (2025). SHP2 inhibition reduces somatotroph tumor growth in a pre-clinical model. Neuro-Oncology. https://doi.org/10.1093/neuonc/noaf057

Chang, W., Tegang, K., Samuels, B. A., Saxe, M., Wichmann, J., David, D. J., David, I. M., Augustin, A., Fischer, H., Golling, S., Lamerz, J., Roth, D., Graf, M., Zoffmann, S., Santarelli, L., Jagasia, R., & Hen, R. (2025). Pharmacological Enhancement of Adult Hippocampal Neurogenesis Improves Behavioral Pattern Separation in Young and Aged Male Mice. Biological Psychiatry Global Open Science, 5(2), 100419. https://doi.org/10.1016/j.bpsgos.2024.100419

Rubinelli, L., Manzo, O. L., Sungho, J., Del Gaudio, I., Bareja, R., Marino, A., Palikhe, S., Di Mauro, V., Bucci, M., Falcone, D. J., Elemento, O., Ersoy, B., Diano, S., Sasset, L., & Di Lorenzo, A. (2025). Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56869-9

Dutta, A., Rodriguez-Calero, A., Ronaldson-Bouchard, K., Offermann, A., Rahman, D., Vhatkar, T. B., Hasson, D., Alshalalfa, M., Davicioni, E., Karnes, R. J., Rubin, M. A., Vunjak-Novakovic, G., Abate-Shen, C., & Arriaga, J. M. (2025). ATAD2 Drives Prostate Cancer Progression to Metastasis. Molecular Cancer Research, OF1–OF12. https://doi.org/10.1158/1541-7786.mcr-24-0544

Steg, P. G., Nicolas, J., Baber, U., Sartori, S., Zhang, Z., Feng, Y., Angiolillo, D. J., Briguori, C., Cohen, D. J., Collier, T., Dangas, G., Dudek, D., Escaned, J., Gibson, C. M., Han, Y.-L., Huber, K., Kastrati, A., Kaul, U., Marx, S. O., … Mehran, R. (2025). Characterizing high-risk enrollment criteria and impact on clinical outcomes in a large randomized clinical trial: Insights from the TWILIGHT trial. American Heart Journal. https://doi.org/10.1016/j.ahj.2025.01.016

Corvo, C., Mendez-David, I., Goutal, S., Saba, W., Bottlaender, M., Caillé, F., Hen, R., Colle, R., Corruble, E., Tournier, N., Leroy, C., & David, D. J. (2025). Synaptic Vesicle 2A (SV2A) Positron Emission Tomography (PET) Imaging as a Marker of Therapeutic Response in a Mouse Model of Depression. ACS Pharmacology & Translational Science, 8(2), 339–345. https://doi.org/10.1021/acsptsci.4c00621

Perry-Hauser, N. A., Du Rand, J. R., Lee, K. H., Shi, L., & Javitch, J. A. (2025). N-terminal fragment shedding contributes to signaling of the full-length adhesion receptor ADGRL3. Journal of Biological Chemistry, 108174. https://doi.org/10.1016/j.jbc.2025.108174

Kim, C., & Yu, Y. (2025). Mechanism of Action of PARP Inhibitors. Annual Review of Cancer Biology, 9(1), 225–244. https://doi.org/10.1146/annurev-cancerbio-042324-103725

Ke, X., van Soldt, B., Vlahos, L., Zhou, Y., Qian, J., George, J., Capdevila, C., Glass, I., Yan, K., Califano, A., & Cardoso, W. V. (2024). Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate. Developmental Cell. https://doi.org/10.1016/j.devcel.2024.11.017

Zahr, T., Li, T., Bhansali, D., Wan, Q., Leong, K. W., & Qiang, L. (2024). Targeted delivery of a cationic dendrimer with a plaque-homing peptide for the treatment of atherosclerosis. Life Medicine. https://doi.org/10.1093/lifemedi/lnae039

del Rivero Morfin, P. J., Chavez, D. S., Jayaraman, S., Yang, L., Geisler, S. M., Kochiss, A. L., Tuluc, P., Colecraft, H. M., Marx, S. O., Liu, X. S., Rajadhyaksha, A. M., & Ben-Johny, M. (2024). A genetically encoded actuator boosts L-type calcium channel function in diverse physiological settings. Science Advances, 10(44). https://doi.org/10.1126/sciadv.adq3374

Matsui, M., Lynch, L. E., Distefano, I., Galante, A., Gade, A. R., Wang, H.-G., Gómez-Banoy, N., Towers, P., Sinden, D. S., Wei, E. Q., Barnett, A. S., Johnson, K., Lima, R., Rubio-Navarro, A., Li, A. K., Marx, S. O., McGraw, T. E., Thornton, P. S., Timothy, K. W., … Pitt, G. S. (2024). Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52885-3

Kassraian, P., Bigler, S. K., Gilly Suarez, D. M., Shrotri, N., Barnett, A., Lee, H.-J., Young, W. S., & Siegelbaum, S. A. (2024). The hippocampal CA2 region discriminates social threat from social safety. Nature Neuroscience, 27(11), 2193–2206. https://doi.org/10.1038/s41593-024-01771-8

Gallitto, M., Zhang, X., De Los Santos, G., Wei, H.-J., Fernández, E. C., Duan, S., Sedor, G., Yoh, N., Kokossis, D., Angel, J. C., Wang, Y.-F., White, E., Kinslow, C. J., Berg, X., Tomassoni, L., Zandkarimi, F., Chio, I. I. C., Canoll, P., Bruce, J. N., … Wu, C.-C. (2024). Targeted delivery of napabucasin with radiotherapy improves outcomes in diffuse midline glioma. Neuro-Oncology. https://doi.org/10.1093/neuonc/noae215

Lin, X., Provasi, D., Niswender, C. M., Asher, W. B., & Javitch, J. A. (2024). Elucidating the molecular logic of a metabotropic glutamate receptor heterodimer. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52822-4

Urso, A., Monk, I. R., Cheng, Y.-T., Predella, C., Wong Fok Lung, T., Theiller, E. M., Boylan, J., Perelman, S., Baskota, S. U., Moustafa, A. M., Lohia, G., Lewis, I. A., Howden, B. P., Stinear, T. P., Dorrello, N. V., Torres, V., & Prince, A. S. (2024). Staphylococcus aureus adapts to exploit collagen-derived proline during chronic infection. Nature Microbiology, 9(10), 2506–2521. https://doi.org/10.1038/s41564-024-01769-9

Abate-Shen, C. (2024). Context-specific targeting of the androgen receptor in prostate cancer. Nature Genetics, 56(10), 2000–2001. https://doi.org/10.1038/s41588-024-01935-z

Olivetti, P. R., Torres-Herraez, A., Gallo, M. E., Raudales, R., Sumerau, M., Moyles, S., Balsam, P. D., & Kellendonk, C. (2024). Inhibition of striatal indirect pathway during second postnatal week leads to long-lasting deficits in motivated behavior. Neuropsychopharmacology. https://doi.org/10.1038/s41386-024-01997-x

Havel, V., Kruegel, A. C., Bechand, B., McIntosh, S., Stallings, L., Hodges, A., Wulf, M. G., Nelson, M., Hunkele, A., Ansonoff, M., Pintar, J. E., Hwu, C., Ople, R. S., Abi-Gerges, N., Zaidi, S. A., Katritch, V., Yang, M., Javitch, J. A., Majumdar, S., … Sames, D. (2024). Oxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-51856-y

Lee, I., Knickerbocker, A. C., Depew, C. R., Martin, E. L., Dicent, J., Miller, G. W., & Bucher, M. L. (2024). Effect of altered production and storage of dopamine on development and behavior in C. elegans. Frontiers in Toxicology, 6. https://doi.org/10.3389/ftox.2024.1374866

L’Esperance, O. J., McGhee, J., Davidson, G., Niraula, S., Smith, A. S., Sosunov, A. A., Yan, S. S., & Subramanian, J. (2024). Functional Connectivity Favors Aberrant Visual Network c-Fos Expression Accompanied by Cortical Synapse Loss in a Mouse Model of Alzheimer’s Disease. Journal of Alzheimer’s Disease, 101(1), 111–131. https://doi.org/10.3233/jad-240776

Petersen, D., Raudales, R., Silva, A. K., Kellendonk, C., & Canetta, S. (2024). Adolescent Thalamoprefrontal Inhibition Leads to Changes in Intrinsic Prefrontal Network Connectivity. Eneuro, 11(8), ENEURO.0284-24.2024. https://doi.org/10.1523/eneuro.0284-24.2024

Wang, X., Marmouzi, I., Finnie, P. S. B., Bucher, M. L., Yan, Y., Williams, E. Q., Støve, S. I., Lipina, T. V., Ramsey, A. J., Miller, G. W., & Salahpour, A. (2024). Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants. Neuropsychopharmacology. https://doi.org/10.1038/s41386-024-01914-2

Samanta, S., Akhter, F., Xue, R., Sosunov, A. A., Wu, L., Chen, D., Arancio, O., Yan, S. F., & Yan, S. S. (2024). Synaptic mitochondria glycation contributes to mitochondrial stress and cognitive dysfunction. Brain. https://doi.org/10.1093/brain/awae229

Bolondi, A., Law, B. K., Kretzmer, H., Gassaloglu, S. I., Buschow, R., Riemenschneider, C., Yang, D., Walther, M., Veenvliet, J. V., Meissner, A., Smith, Z. D., & Chan, M. M. (2024). Reconstructing axial progenitor field dynamics in mouse stem cell-derived embryoids. Developmental Cell, 59(12), 1489-1505.e14. https://doi.org/10.1016/j.devcel.2024.03.024

Abate-Shen, C., & Politi, K. (2024). The Evolution of Mouse Models of Cancer: Past, Present, and Future. Cold Spring Harbor Perspectives in Medicine, a041736. https://doi.org/10.1101/cshperspect.a041736

Katchman, A. N., Zakharov, S. I., Bohnen, M. S., Sanchez Jimenez, A., Kushner, J. S., Yang, L., Chen, B., Nasari, A., Liu, G., Rabbani, D. E., Han, J., Leu, C.-S., Pitt, G. S., & Marx, S. O. (2024). Augmented Cardiac Inotropy by Phosphodiesterase Inhibition Requires Phosphorylation of Rad and Increased Calcium Current. Circulation, 149(20), 1617–1620. https://doi.org/10.1161/circulationaha.123.067298

Zuo, H., Park, J., Frangaj, A., Ye, J., Lu, G., Manning, J. J., Asher, W. B., Lu, Z., Hu, G., Wang, L., Mendez, J., Eng, E., Zhang, Z., Lin, X., Grassucci, R., Hendrickson, W. A., Clarke, O. B., Javitch, J. A., Conigrave, A. D., & Fan, Q. R. (2024). Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 629(8011), 481–488. https://doi.org/10.1038/s41586-024-07331-1

Samanta, S., Akhter, F., Roy, A., Chen, D., Turner, B., Wang, Y., Clemente, N., Wang, C., Swerdlow, R. H., Battaile, K. P., Lovell, S., Yan, S. F., & Yan, S. S. (2023). New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer’s disease. Brain, 147(5), 1710–1725. https://doi.org/10.1093/brain/awad432

Castillo, P. E., Desarménien, M. G., & Siegelbaum, S. A. (2024). Vivien Chevaleyre (1973–2024). Neuron, 112(9), 1387–1389. https://doi.org/10.1016/j.neuron.2024.03.030

Papachristodoulou, A., Heidegger, I., Virk, R. K., Di Bernardo, M., Kim, J. Y., Laplaca, C., Picech, F., Schäfer, G., De Castro, G. J., Hibshoosh, H., Loda, M., Klocker, H., Rubin, M. A., Zheng, T., Benson, M. C., McKiernan, J. M., Dutta, A., & Abate-Shen, C. (2024). Metformin Overcomes the Consequences of NKX3.1 Loss to Suppress Prostate Cancer Progression. European Urology, 85(4), 361–372. https://doi.org/10.1016/j.eururo.2023.07.016

Lee, W.-L., Westergaard, X., Hwu, C., Hwu, J., Fiala, T., Lacefield, C., Boltaev, U., Mendieta, A. M., Lin, L., Sonders, M. S., Brown, K. R., He, K., Asher, W. B., Javitch, J. A., Sulzer, D., & Sames, D. (2024). Molecular Design of SERTlight: A Fluorescent Serotonin Probe for Neuronal Labeling in the Brain. Journal of the American Chemical Society, 146(14), 9564–9574. https://doi.org/10.1021/jacs.3c11617

Bucher, M. L., Dunn, A. R., Bradner, J. M., Egerton, K. S., Burkett, J. P., Johnson, M. A., & Miller, G. W. (2024). Synaptic vesicle glycoprotein 2C enhances vesicular storage of dopamine and counters dopaminergic toxicity. European Journal of Neuroscience, 59(10), 2483–2501. Portico. https://doi.org/10.1111/ejn.16311

Bekdash, R., Yoshida, K., Nair, M. S., Qiu, L., Ahdout, J., Tsai, H.-Y., Uryu, K., Soni, R. K., Huang, Y., Ho, D. D., & Yazawa, M. (2024). Developing inhibitory peptides against SARS-CoV-2 envelope protein. PLOS Biology, 22(3), e3002522. https://doi.org/10.1371/journal.pbio.3002522

Arriaga, J. M., Ronaldson-Bouchard, K., Picech, F., Nunes de Almeida, F., Afari, S., Chhouri, H., Vunjak-Novakovic, G., & Abate-Shen, C. (2024). In vivo genome-wide CRISPR screening identifies CITED2 as a driver of prostate cancer bone metastasis. Oncogene, 43(17), 1303–1315. https://doi.org/10.1038/s41388-024-02995-5

Qi, L., Iskols, M., Shi, D., Reddy, P., Walker, C., Lezgiyeva, K., Voisin, T., Pawlak, M., Kuchroo, V. K., Chiu, I. M., Ginty, D. D., & Sharma, N. (2024). A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes. Cell, 187(6), 1508-1526.e16. https://doi.org/10.1016/j.cell.2024.02.006

Gelsinger, D. R., Vo, P. L. H., Klompe, S. E., Ronda, C., Wang, H. H., & Sternberg, S. H. (2024). Bacterial genome engineering using CRISPR-associated transposases. Nature Protocols, 19(3), 752–790. https://doi.org/10.1038/s41596-023-00927-3

Deng, H., Deng, H., Kim, C., Li, P., Wang, X., Yu, Y., & Qin, T. (2023). Synthesis of nimbolide and its analogues and their application as poly(ADP-ribose) polymerase-1 trapping inducers. Nature Synthesis, 3(3), 378–385. https://doi.org/10.1038/s44160-023-00437-w

Boyle, L. M., Posani, L., Irfan, S., Siegelbaum, S. A., & Fusi, S. (2024). Tuned geometries of hippocampal representations meet the computational demands of social memory. Neuron, 112(8), 1358-1371.e9. https://doi.org/10.1016/j.neuron.2024.01.021

Tsai, M.-H. M., Chen, L., Baumann, M. H., Canals, M., Javitch, J. A., Lane, J. R., & Shi, L. (2024). In Vitro Functional Profiling of Fentanyl and Nitazene Analogs at the μ-Opioid Receptor Reveals High Efficacy for Gi Protein Signaling. ACS Chemical Neuroscience, 15(4), 854–867. https://doi.org/10.1021/acschemneuro.3c00750

Niraula, S., Yan, S. S., & Subramanian, J. (2023). Amyloid Pathology Impairs Experience-Dependent Inhibitory Synaptic Plasticity. The Journal of Neuroscience, 44(5), e0702232023. https://doi.org/10.1523/jneurosci.0702-23.2023

Zahr, T., Boda, V. K., Ge, J., Yu, L., Wu, Z., Que, J., Li, W., & Qiang, L. (2024). Small molecule conjugates with selective estrogen receptor β agonism promote anti-aging benefits in metabolism and skin recovery. Acta Pharmaceutica Sinica B, 14(5), 2137–2152. https://doi.org/10.1016/j.apsb.2024.01.014

Weng, C., Yu, F., Yang, D., Poeschla, M., Liggett, L. A., Jones, M. G., Qiu, X., Wahlster, L., Caulier, A., Hussmann, J. A., Schnell, A., Yost, K. E., Koblan, L. W., Martin-Rufino, J. D., Min, J., Hammond, A., Ssozi, D., Bueno, R., Mallidi, H., … Sankaran, V. G. (2024). Deciphering cell states and genealogies of human haematopoiesis. Nature, 627(8003), 389–398. https://doi.org/10.1038/s41586-024-07066-z

Kim, C., Wang, X.-D., Liu, Z., Hao, J., Wang, S., Li, P., Zi, Z., Ding, Q., Jang, S., Kim, J., Luo, Y., Huffman, K. E., Pal Choudhuri, S., del Rio, S., Cai, L., Liang, H., Drapkin, B. J., Minna, J. D., & Yu, Y. (2024). Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors. Science Advances, 10(3). https://doi.org/10.1126/sciadv.adh2579

Papa, A., del Rivero Morfin, P. J., Chen, B.-X., Yang, L., Katchman, A. N., Zakharov, S. I., Liu, G., Bohnen, M. S., Zheng, V., Katz, M., Subramaniam, S., Hirsch, J. A., Weiss, S., Dascal, N., Karlin, A., Pitt, G. S., Colecraft, H. M., Ben-Johny, M., & Marx, S. O. (2024). A membrane-associated phosphoswitch in Rad controls adrenergic regulation of cardiac calcium channels. Journal of Clinical Investigation, 134(5). https://doi.org/10.1172/jci176943

Liu, B., Xie, D., Huang, X., Jin, S., Dai, Y., Sun, X., Li, D., Bennett, A. M., Diano, S., & Huang, Y. (2024). Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α. Diabetologia, 67(4), 724–737. https://doi.org/10.1007/s00125-023-06073-5

Pakula, H., Omar, M., Carelli, R., Pederzoli, F., Fanelli, G. N., Pannellini, T., Socciarelli, F., Van Emmenis, L., Rodrigues, S., Fidalgo-Ribeiro, C., Nuzzo, P. V., Brady, N. J., Dinalankara, W., Jere, M., Valencia, I., Saladino, C., Stone, J., Unkenholz, C., Garner, R., … Loda, M. (2024). Distinct mesenchymal cell states mediate prostate cancer progression. Nature Communications, 15(1). https://doi.org/10.1038/s41467-023-44210-1