Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice

Wang, Y., Shilagardi, K., Hsu, T., Odinammadu, K. O., Maruyama, T., Wu, W., Lin, C.-S., Damoci, C. B., Spear, E. D., Shin, J.-Y., Hsu, W., Michaelis, S., & Worman, H. J. (2022). Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice. Proceedings of the National Academy of Sciences, 119(9). https://doi.org/10.1073/pnas.2118695119
Authors:
Yuexia Wang
Khurts Shilagardi
Trunee Hsu
Kamsi O. Odinammadu
Takamitsu Maruyama
Wei Wu
Chyuan-Sheng Lin
Christopher B. Damoci
Eric D. Spear
Ji-Yeon Shin
Wei Hsu
Howard J. Worman
Susan Michaelis
Affiliated Authors:
Yuexia Wang
Wei Wu
Chyuan-Sheng Lin
Christopher B. Damoci
Ji-Yeon Shin
Howard J. Worman
Author Keywords:
aging
bone
lamin
nuclear envelope
progeria
Publication Type:
Article
Unique ID:
10.1073/pnas.2118695119
PMID:
Publication Date:
Data Source:
Scopus

Record Created: