Department of Genetics and Development

Displaying 1 - 50 of 413CSV
Mosialou, I., Ali, A. M., Labella, R., Bisikirska, B., Cuesta-Dominguez, A., Vgenopoulou, P., Reyes, I., Rao, S. M., Wang, A., Luo, N., Galan-Diez, M., Zhao, J., Chernak, B. J., Bewersdorf, J. P., Fukasawa, K., Su, J., Higa, J., Adams, R. A., Corper, A. L., … Kousteni, S. (2025). A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies. Cancer Cell. https://doi.org/10.1016/j.ccell.2025.03.007
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Melgarejo, J. D., Patil, D., Charisis, S., Vatcheva, K. P., Mejia-Arango, S., Mena, L. J., Satizabal, C. L., Gaona, C., Silva, E., Manusov, E., Lee, J. H., Terwilliger, J. D., Gutierrez, J., Seshadri, S., & Maestre, G. E. (2025). Baseline associations of office and ambulatory blood pressure monitoring with cognitive function and dementia prevalence. Journal of Alzheimer’s Disease. https://doi.org/10.1177/13872877251322400
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Mannowetz, N., Chung, S. S. W., Maitra, S., Noman, M. A. A., Wong, H. L., Cheryala, N., Bakshi, A., Wolgemuth, D. J., & Georg, G. I. (2025). Targeting the retinoid signaling pathway with YCT-529 for effective and reversible oral contraception in mice and primates. Communications Medicine, 5(1). https://doi.org/10.1038/s43856-025-00752-7
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Mangione, R. M., Pierce, S., Zheng, M., Martin, R. M., Goncalves, C., Kumar, A., Scaglione, S., de Sousa Morgado, C., Penzo, A., Lancrey, A., Reid, R. J. D., Lautier, O., Gaillard, P.-H., Stirling, P. C., de Almeida, S. F., Rothstein, R., & Palancade, B. (2025). DNA lesions can frequently precede DNA:RNA hybrid accumulation. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57588-x
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Ansere, V. A., Kim, S.-S., Marino, F., Morillo, K., Dubal, D. B., Murphy, C. T., Suh, Y., & Benayoun, B. A. (2025). Strategies for studying sex differences in brain aging. Trends in Genetics. https://doi.org/10.1016/j.tig.2025.02.001
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Morano, N. C., Lopez, D. H., Meltzer, H., Sergeeva, A. P., Katsamba, P. S., Rostam, K. D., Gupta, H. P., Becker, J. E., Bornstein, B., Cosmanescu, F., Schuldiner, O., Honig, B., Mann, R. S., & Shapiro, L. (2025). Members of the DIP and Dpr adhesion protein families use cis inhibition to shape neural development in Drosophila. PLOS Biology, 23(3), e3003030. https://doi.org/10.1371/journal.pbio.3003030
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Sharan, K., Brandt, C., Yusuf, M. A., Singh, P., Halder, N., Edwards, M. E., Mangu, S. R., Das, A., Mishra, A., Kumar, S. S., Sharma, A., Gupta, A., Liu, X. S., Guo, E. X., Monani, U. R., Ponnalagu, D., Ivanov, I. I., Lal, G., Clare, S., … Yadav, V. K. (2025). Rapid and relaying deleterious effects of a gastrointestinal pathogen, Citrobacter rodentium, on bone, an extra-intestinal organ. IScience, 28(2), 111802. https://doi.org/10.1016/j.isci.2025.111802
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Rogina, B., Anderson, R., Lebrasseur, N., Curan, S., Yousefzadeh, M. J., Ghosh, B., Duque, G., Howlett, S., Austad, S., Demuth, I., Gerstorf, D., Korfhage, J., Lombard, D. B., Abadir, P., Christensen, K., Carey, J. R., Alberts, S. C., Campos, F., Palavicini, J. P., … Rappaport, N. (2025). Symposia Report of The Annual Biological Sciences Section Meeting of the Gerontological Society of America 2023, Tampa, Florida. The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences. https://doi.org/10.1093/gerona/glaf026
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Mondal, J., Zhang, J., Qing, F., Li, S., Kumar, D., Huse, J. T., & Giancotti, F. G. (2025). Brd7 loss reawakens dormant metastasis initiating cells in lung by forging an immunosuppressive niche. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56347-2
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Vinogradova, E., Jarmukhanov, Z., Nurgaziyev, M., Kossumov, A., Nurgozhina, A., Mukhanbetzhanov, N., Sergazy, S., Chulenabyeva, L., Issilbayeva, A., Askarova, S., Kaiyrlykyzy, A., Rakhimova, S., Kozhamkulov, U., Kairov, U., Khassenbekova, Z., Tarzhanova, D., Akilzhanova, A., Lee, J. H., Terwilliger, J., … Kushugulova, A. (2025). Enterococcus dysbiosis as a mediator of vitamin D deficiency-associated memory impairments. Heliyon, 11(2), e41969. https://doi.org/10.1016/j.heliyon.2025.e41969
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Fu, X., Mo, S., Buendia, A., Laurent, A. P., Shao, A., Alvarez-Torres, M. del M., Yu, T., Tan, J., Su, J., Sagatelian, R., Ferrando, A. A., Ciccia, A., Lan, Y., Owens, D. M., Palomero, T., Xing, E. P., & Rabadan, R. (2025). A foundation model of transcription across human cell types. Nature, 637(8047), 965–973. https://doi.org/10.1038/s41586-024-08391-z
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Park, D., Phoung, S., Borei, P., Bang, M., Kim, S., Suh, Y., Kim, H. S., & Kim, J. H. (2025). Association of Right Bundle Branch Block with Ischemic Stroke Incidence: A UK Biobank Cohort Study. Cerebrovascular Diseases, 1–14. Portico. https://doi.org/10.1159/000543258
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Kittle, R. H., & Levo, M. (2025). Exploring the interplay between enhancer–promoter interactions and transcription. Current Opinion in Genetics & Development, 90, 102303. https://doi.org/10.1016/j.gde.2024.102303
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Duan, S., Nodelman, I. M., Zhou, H., Tsukiyama, T., Bowman, G. D., & Zhang, Z. (2025). H3K56 acetylation regulates chromatin maturation following DNA replication. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55144-7
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Goda, C., Kulkarni, R., Bustos, Y., Li, W., Rudich, A., Balcioglu, O., Chidester, S., Urs, A. P., Karunasiri, M., Al-Marrawi, Y., Korn, E., Kanna, S., Garfinkle, E. A. R., Shah, N., Wooten, A., Mundy-Bosse, B., Sehgal, L., Zhang, B., Marcucci, G., … Dorrance, A. M. (2024). Cellular taxonomy of the preleukemic bone marrow niche of acute myeloid leukemia. Leukemia, 39(1), 51–63. https://doi.org/10.1038/s41375-024-02415-3
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Merello Oyarzún, G., Olivares-Costa, M., Basile, L., Pástor, T. P., Mendoza-Soto, P., Padilla-Santiago, L., Mardones, G. A., Binda, C., & Opazo, J. C. (2025). Evolutionary and Functional Analysis of Monoamine Oxidase F (MAO F): A Novel Member of the MAO Gene Family. Genome Biology and Evolution. https://doi.org/10.1093/gbe/evae280
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Zhang, J.-S., Dhlamini, Q., Guo, Q., Quan, M., Wu, J., Lyu, H., Chong, L., Lv, Y., Lin, Y., Zhou, B., Liu, Y., Ji, H., Lin, X., Ning, W., Sui, P., Chen, H., Gao, P., Chen, W., Peter Di, Y., … Jiang, D. (2024). Progress and Gaps in Respiratory Disease Research and Treatment: Highlights of the IRM 2024 in Shanghai. Journal of Respiratory Biology and Translational Medicine, 1(4), 10021–10021. https://doi.org/10.70322/jrbtm.2024.10021
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Arias, R. A., & Tomlinson, A. (2025). Decoding a Cell’s Fate: How Notch and receptor tyrosine kinase signals specify the Drosophila R7 photoreceptor. Developmental Biology, 519, 21–29. https://doi.org/10.1016/j.ydbio.2024.12.001
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Sierra, J., Portela-Lomba, M., Simón, D., & Moreno-Flores, M. T. (2024). Reprogramming induced neurons from olfactory ensheathing glial cells: a feasible approach for spinal cord injury repair. Neural Regeneration Research. https://doi.org/10.4103/nrr.nrr-d-24-01043
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Kimble, M. T., Sane, A., Reid, R. J. D., Johnson, M. J., Rothstein, R., & Symington, L. S. (2025). Repair of replication-dependent double-strand breaks differs between the leading and lagging strands. Molecular Cell, 85(1), 61-77.e6. https://doi.org/10.1016/j.molcel.2024.10.032
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De Felice, D., Alaimo, A., Bressan, D., Genovesi, S., Marmocchi, E., Annesi, N., Beccaceci, G., Dalfovo, D., Cutrupi, F., Medaglia, S., Foletto, V., Lorenzoni, M., Gandolfi, F., Kannan, S., Verma, C. S., Vasciaveo, A., Shen, M. M., Romanel, A., Chiacchiera, F., … Lunardi, A. (2024). Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer. EMBO Reports. https://doi.org/10.1038/s44319-024-00335-y
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Mavros, C. F., Bongers, M., Neergaard, F. B. F., Cusimano, F., Sun, Y., Kaufman, A., Richardson, M., Kammler, S., Kristensen, M., Sommer, M. O. A., & Wang, H. H. (2024). Bacteria Engineered to Produce Serotonin Modulate Host Intestinal Physiology. ACS Synthetic Biology. https://doi.org/10.1021/acssynbio.4c00453
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Jin, C., Wang, X., Yang, J., Kim, S., Hudgins, A. D., Gamliel, A., Pei, M., Contreras, D., Devos, M., Guo, Q., Vijg, J., Conti, M., Hoeijmakers, J., Campisi, J., Lobo, R., Williams, Z., Rosenfeld, M. G., & Suh, Y. (2024). Molecular and genetic insights into human ovarian aging from single-nuclei multi-omics analyses. Nature Aging. https://doi.org/10.1038/s43587-024-00762-5
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Ounadjela, J. R., Zhang, K., Kobayashi-Kirschvink, K. J., Jin, K., J. C. Russell, A., Lackner, A. I., Callahan, C., Viggiani, F., Dey, K. K., Jagadeesh, K., Maxian, T., Prandstetter, A.-M., Nadaf, N., Gong, Q., Raichur, R., Zvezdov, M. L., Hui, M., Simpson, M., Liu, X., … Shu, J. (2024). Spatial multiomic landscape of the human placenta at molecular resolution. Nature Medicine. https://doi.org/10.1038/s41591-024-03073-9
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Israeel, M., Iqbal, J., Abbasi, B. A., Ijaz, S., Ullah, R., Zarshan, F., Yaseen, T., Khan, G., Murtaza, G., Ali, I., Alarjani, K. M., Elshikh, M. S., Rizwan, M., Khan, S., & Iqbal, R. (2024). Potential biological applications of environment friendly synthesized iron oxide nanoparticles using Sageretia thea root extract. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-79953-4
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Park, M., Nam, J. S., Kim, T., Yoon, G., Kim, S., Lee, C., Lee, C. G., Park, S., Bejoymohandas, K. S., Yang, J., Kwon, Y. H., Lee, Y. J., Seo, J. K., Min, D., Park, T., & Kwon, T. (2024). Rational Design of Biocompatible Ir(III) Photosensitizer to Overcome Drug‐Resistant Cancer via Oxidative Autophagy Inhibition. Advanced Science. Portico. https://doi.org/10.1002/advs.202407236
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Cerutti, G., Arias, R., Bahna, F., Mannepalli, S., Katsamba, P. S., Ahlsen, G., Kloss, B., Bruni, R., Tomlinson, A., & Shapiro, L. (2024). Structures and pH-dependent dimerization of the sevenless receptor tyrosine kinase. Molecular Cell, 84(23), 4677-4690.e6. https://doi.org/10.1016/j.molcel.2024.10.017
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Mohite, P., Sule, S., Pawar, A., Alharbi, H. M., Maitra, S., Subramaniyan, V., Kumarasamy, V., Uti, D. E., Ogbu, C. O., Oodo, S. I., Kumer, A., Idowu, A. O., & Okoye, O. N. N. (2024). Development and characterization of a self-nano emulsifying drug delivery system (SNEDDS) for Ornidazole to improve solubility and oral bioavailability of BCS class II drugs. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-73760-7
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Leifer, V. P., Fang, F., Song, L., Kim, J., Papanikolaou, J. F., Smeeton, J., & Thomopoulos, S. (2024). Single-cell RNA-sequencing analysis of immune and mesenchymal cell crosstalk in the developing enthesis. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-77958-7
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Connors, C. Q., Martin, S. L., Dumont, J., Shirasu-Hiza, M., & Canman, J. C. (2024). Cell type-specific regulation by different cytokinetic pathways in the early embryo. MicroPublication Biology. https://doi.org/10.17912/MICROPUB.BIOLOGY.001316
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Gao, V. R., Yang, R., Das, A., Luo, R., Luo, H., McNally, D. R., Karagiannidis, I., Rivas, M. A., Wang, Z.-M., Barisic, D., Karbalayghareh, A., Wong, W., Zhan, Y. A., Chin, C. R., Noble, W. S., Bilmes, J. A., Apostolou, E., Kharas, M. G., Béguelin, W., … Leslie, C. S. (2024). ChromaFold predicts the 3D contact map from single-cell chromatin accessibility. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-53628-0
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Melgarejo, J. D., Vatcheva, K. P., Mejia-Arango, S., Charisis, S., Patil, D., Mena, L. J., Garcia, A., Alliey-Rodriguez, N., Satizabal, C. L., Chavez, C. A., Gaona, C., Silva, E., Mavarez, R. P., Lee, J. H., Terwilliger, J. D., Blangero, J., Seshadri, S., & Maestre, G. E. (2024). Association of longitudinal changes in 24-h blood pressure level and variability with cognitive decline. Journal of Hypertension, 42(11), 1985–1993. https://doi.org/10.1097/hjh.0000000000003824
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Nam, J. S., Dixon, M. S., & Chio, I. I. C. (2024). Hydrogen sulfide: A whiff of trouble for cancer cell survival. Molecular Cell, 84(20), 3865–3867. https://doi.org/10.1016/j.molcel.2024.09.027
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Lyu, Y.-X., Fu, Q., Wilczok, D., Ying, K., King, A., Antebi, A., Vojta, A., Stolzing, A., Moskalev, A., Georgievskaya, A., Maier, A. B., Olsen, A., Groth, A., Simon, A. K., Brunet, A., Jamil, A., Kulaga, A., Bhatti, A., Yaden, B., … Bakula, D. (2024). Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity. Aging. https://doi.org/10.18632/aging.206135
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Ardanaz, C. G., de la Cruz, A., Minhas, P. S., Hernández-Martín, N., Pozo, M. Á., Valdecantos, M. P., Valverde, Á. M., Villa-Valverde, P., Elizalde-Horcada, M., Puerta, E., Ramírez, M. J., Ortega, J. E., Urbiola, A., Ederra, C., Ariz, M., Ortiz-de-Solórzano, C., Fernández-Irigoyen, J., Santamaría, E., Karsenty, G., … Solas, M. (2024). Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis. Science Advances, 10(42). https://doi.org/10.1126/sciadv.adp1115
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Bisikirska, B., Labella, R., Cuesta-Dominguez, A., Luo, N., De Angelis, J., Mosialou, I., Lin, C.-S., Beck, D., Lata, S., Shyu, P. T., McMahon, D. J., Guo, E., Hagen, J., Chung, W. K., Shane, E., Cohen, A., & Kousteni, S. (2024). Melatonin receptor 1A variants as genetic cause of idiopathic osteoporosis. Science Translational Medicine, 16(769). https://doi.org/10.1126/scitranslmed.adj0085
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Shipman, G. A., Padilla, R., Horth, C., Hu, B., Bareke, E., Vitorino, F. N., Gongora, J. M., Garcia, B. A., Lu, C., & Majewski, J. (2024). Systematic perturbations of SETD2, NSD1, NSD2, NSD3, and ASH1L reveal their distinct contributions to H3K36 methylation. Genome Biology, 25(1). https://doi.org/10.1186/s13059-024-03415-3
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Shore, A. N., Li, K., Safari, M., Qunies, A. M., Spitznagel, B. D., Weaver, C. D., Emmitte, K., Frankel, W., & Weston, M. C. (2024). Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on somatostatin- and parvalbumin-expressing cortical GABAergic neurons. ELife, 13. CLOCKSS. https://doi.org/10.7554/elife.92915
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Liebau, R. C., Waters, C., Ahmed, A., Soni, R. K., & Gautier, J. (2024). UVSSA facilitates transcription-coupled repair of DNA interstrand crosslinks. DNA Repair, 143, 103771. https://doi.org/10.1016/j.dnarep.2024.103771
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Zhang, Y., Karagiannis, D., Liu, H., Lin, M., Fang, Y., Jiang, M., Chen, X., Suresh, S., Huang, H., She, J., Shi, F., Liu, J., Luo, D., Angel, J. C., Lin, G., Yang, P., El-Rifai, W., Zaika, A., Oro, A. E., … Que, J. (2024). Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy. Science Advances, 10(41). https://doi.org/10.1126/sciadv.adq0479
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Gu, J., Iyer, A., Wesley, B., Taglialatela, A., Leuzzi, G., Hangai, S., Decker, A., Gu, R., Klickstein, N., Shuai, Y., Jankovic, K., Parker-Burns, L., Jin, Y., Zhang, J. Y., Hong, J., Niu, X., Costa, J. A., Pezet, M. G., Chou, J., … Gaublomme, J. T. (2024). Mapping multimodal phenotypes to perturbations in cells and tissue with CRISPRmap. Nature Biotechnology. https://doi.org/10.1038/s41587-024-02386-x
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Wang, W., Williams, D. J., Teoh, J. J., Soundararajan, D., Zuberi, A., Lutz, C. M., Frankel, W. N., & Makinson, C. D. (2024). Impaired axon initial segment structure and function in a model of ARHGEF9 developmental and epileptic encephalopathy. Proceedings of the National Academy of Sciences, 121(42). https://doi.org/10.1073/pnas.2400709121
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