Department of Microbiology and Immunology

Displaying 151 - 200 of 355CSV
Wang, Q., Guo, Y., Tam, A. R., Valdez, R., Gordon, A., Liu, L., & Ho, D. D. (2023). Deep immunological imprinting due to the ancestral spike in the current bivalent COVID-19 vaccine. Cell Reports Medicine, 4(11), 101258. https://doi.org/10.1016/j.xcrm.2023.101258
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Detomasi, T. C., Batka, A. E., Valastyan, J. S., Hydorn, M. A., Craik, C. S., Bassler, B. L., & Marletta, M. A. (2023). Proteases influence colony aggregation behavior in Vibrio cholerae. Journal of Biological Chemistry, 299(12), 105386. https://doi.org/10.1016/j.jbc.2023.105386
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Wang, Q., Guo, Y., Liu, L., Schwanz, L. T., Li, Z., Nair, M. S., Ho, J., Zhang, R. M., Iketani, S., Yu, J., Huang, Y., Qu, Y., Valdez, R., Lauring, A. S., Huang, Y., Gordon, A., Wang, H. H., Liu, L., & Ho, D. D. (2023). Antigenicity and receptor affinity of SARS-CoV-2 BA.2.86 spike. Nature, 624(7992), 639–644. https://doi.org/10.1038/s41586-023-06750-w
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Dorrity, T. J., Shin, H., Wiegand, K. A., Aruda, J., Closser, M., Jung, E., Gertie, J. A., Leone, A., Polfer, R., Culbertson, B., Yu, L., Wu, C., Ito, T., Huang, Y., Steckelberg, A.-L., Wichterle, H., & Chung, H. (2023). Long 3′UTRs predispose neurons to inflammation by promoting immunostimulatory double-stranded RNA formation. Science Immunology, 8(88). https://doi.org/10.1126/sciimmunol.adg2979
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Hirakawa, H., Gao, L., Tavakol, D. N., Vunjak-Novakovic, G., & Ding, L. (2023). Cellular plasticity of the bone marrow niche promotes hematopoietic stem cell regeneration. Nature Genetics, 55(11), 1941–1952. https://doi.org/10.1038/s41588-023-01528-2
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Andino, R., Kirkegaard, K., Macadam, A., Racaniello, V. R., & Rosenfeld, A. B. (2023). The Picornaviridae Family: Knowledge Gaps, Animal Models, Countermeasures, and Prototype Pathogens. The Journal of Infectious Diseases, 228(Supplement_6), S427–S445. https://doi.org/10.1093/infdis/jiac426
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Wang, Q., Li, Z., Guo, Y., Mellis, I. A., Iketani, S., Liu, M., Yu, J., Valdez, R., Lauring, A. S., Sheng, Z., Gordon, A., Liu, L., & Ho, D. D. (2023). Evolving antibody evasion and receptor affinity of the Omicron BA.2.75 sublineage of SARS-CoV-2. IScience, 26(11), 108254. https://doi.org/10.1016/j.isci.2023.108254
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Soni, M. K., Migliori, E., Fu, J., Assal, A., Chan, H. T., Pan, J., Khatiwada, P., Ciubotariu, R., May, M. S., Pereira, M. R., De Giorgi, V., Sykes, M., Mapara, M. Y., & Muranski, P. J. (2023). The prospect of universal coronavirus immunity: characterization of reciprocal and non-reciprocal T cell responses against SARS-CoV2 and common human coronaviruses. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1212203
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Berton, R. R., McGonagil, P. W., Jensen, I. J., Ybarra, T. K., Bishop, G. A., Harty, J. T., Griffith, T. S., & Badovinac, V. P. (2023). Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells. PLOS Pathogens, 19(10), e1011720. https://doi.org/10.1371/journal.ppat.1011720
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Vincent, R. L., Gurbatri, C. R., Li, F., Vardoshvili, A., Coker, C., Im, J., Ballister, E. R., Rouanne, M., Savage, T., de los Santos-Alexis, K., Redenti, A., Brockmann, L., Komaranchath, M., Arpaia, N., & Danino, T. (2023). Probiotic-guided CAR-T cells for solid tumor targeting. Science, 382(6667), 211–218. https://doi.org/10.1126/science.add7034
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Tran, L. M., Macedo, C., Zahorchak, A. F., Gu, X., Elinoff, B., Singhi, A. D., Isett, B., Zeevi, A., Sykes, M., Breen, K., Srivastava, A., Ables, E. M., Landsittel, D., Styn, M. A., Humar, A., Lakkis, F. G., Metes, D. M., & Thomson, A. W. (2023). Donor-derived regulatory dendritic cell infusion modulates effector CD8 + T cell and NK cell responses after liver transplantation. Science Translational Medicine, 15(717). https://doi.org/10.1126/scitranslmed.adf4287
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Hart, S. F. M., Yonemitsu, M. A., Giersch, R. M., Garrett, F. E. S., Beal, B. F., Arriagada, G., Davis, B. W., Ostrander, E. A., Goff, S. P., & Metzger, M. J. (2023). Centuries of genome instability and evolution in soft-shell clam, Mya arenaria, bivalve transmissible neoplasia. Nature Cancer, 4(11), 1561–1574. https://doi.org/10.1038/s43018-023-00643-7
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van der Plas, J. L., Kuiper, V. P., Bagchus, W. M., Bödding, M., Yalkinoglu, Ö., Tappert, A., Seitzinger, A., Spangenberg, T., Bezuidenhout, D., Wilkins, J., Oeuvray, C., Dhingra, S. K., Thathy, V., Fidock, D. A., Smidt, L. C. A., Roozen, G. V. T., Koopman, J. P. R., Lamers, O. A. C., Sijtsma, J., … Khandelwal, A. (2023). Causal chemoprophylactic activity of cabamiquine against Plasmodium falciparum in a controlled human malaria infection: a randomised, double-blind, placebo-controlled study in the Netherlands. The Lancet Infectious Diseases, 23(10), 1164–1174. https://doi.org/10.1016/s1473-3099(23)00212-8
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Siqueira-Neto, J. L., Wicht, K. J., Chibale, K., Burrows, J. N., Fidock, D. A., & Winzeler, E. A. (2023). Antimalarial drug discovery: progress and approaches. Nature Reviews Drug Discovery, 22(10), 807–826. https://doi.org/10.1038/s41573-023-00772-9
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Liu, L., Casner, R. G., Guo, Y., Wang, Q., Iketani, S., Chan, J. F.-Woo., Yu, J., Dadonaite, B., Nair, M. S., Mohri, H., Reddem, E. R., Yuan, S., Poon, V. K.-M., Chan, C. C.-S., Yuen, K.-Y., Sheng, Z., Huang, Y., Bloom, J. D., Shapiro, L., & Ho, D. D. (2023). Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking. Immunity, 56(10), 2442-2455.e8. https://doi.org/10.1016/j.immuni.2023.09.003
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Wang, P. H., Washburn, R. S., Mariuzza, D. L., Lin, W.-H. W., Gill, A. L., Ahmed, R., & Reiner, S. L. (2023). Reciprocal transmission of activating and inhibitory signals and cell fate in regenerating T cells. Cell Reports, 42(10), 113155. https://doi.org/10.1016/j.celrep.2023.113155
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Bennett, J. M., Ward, K. E., Muir, R. K., Kabeche, S., Yoo, E., Yeo, T., Lam, G., Zhang, H., Almaliti, J., Berger, G., Faucher, F. F., Lin, G., Gerwick, W. H., Yeh, E., Fidock, D. A., & Bogyo, M. (2023). Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum. ACS Infectious Diseases, 9(10), 2036–2047. https://doi.org/10.1021/acsinfecdis.3c00310
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Duan, Y., Zhou, H., Liu, X., Iketani, S., Lin, M., Zhang, X., Bian, Q., Wang, H., Sun, H., Hong, S. J., Culbertson, B., Mohri, H., Luck, M. I., Zhu, Y., Liu, X., Lu, Y., Yang, X., Yang, K., Sabo, Y., … Yang, H. (2023). Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir. Nature, 622(7982), 376–382. https://doi.org/10.1038/s41586-023-06609-0
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Yuan, M., Yang, B., Rothschild, G., Mann, J. J., Sanford, L. D., Tang, X., Huang, C., Wang, C., & Zhang, W. (2023). Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential. Signal Transduction and Targeted Therapy, 8(1). https://doi.org/10.1038/s41392-023-01519-z
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Nguyen, S. N., Vinogradsky, A. V., Ferrari, G., Sykes, M., Bacha, E. A., Richmond, M. E., & Goldstone, A. B. (2023). Pitfalls and Future Directions of Contemporary Pediatric Valve Surgery: the Case for Living Valve Substitutes. Current Pediatrics Reports, 11(4), 180–192. https://doi.org/10.1007/s40124-023-00295-2
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Connors, T. J., Matsumoto, R., Verma, S., Szabo, P. A., Guyer, R., Gray, J., Wang, Z., Thapa, P., Dogra, P., Poon, M. M. L., Rybkina, K., Bradley, M. C., Idzikowski, E., McNichols, J., Kubota, M., Pethe, K., Shen, Y., Atkinson, M. A., Brusko, M., … Farber, D. L. (2023). Site-specific development and progressive maturation of human tissue-resident memory T cells over infancy and childhood. Immunity, 56(8), 1894-1909.e5. https://doi.org/10.1016/j.immuni.2023.06.008
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Rybkina, K., Bell, J. N., Bradley, M. C., Wohlbold, T., Scafuro, M., Meng, W., Korenberg, R. C., Davis-Porada, J., Anderson, B. R., Weller, R. J., Milner, J. D., Moscona, A., Porotto, M., Luning Prak, E. T., Pethe, K., Connors, T. J., & Farber, D. L. (2023). SARS-CoV-2 infection and recovery in children: Distinct T cell responses in MIS-C compared to COVID-19. Journal of Experimental Medicine, 220(8). https://doi.org/10.1084/jem.20221518
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Gill, A. L., Wang, P. H., Lee, J., Hudson, W. H., Ando, S., Araki, K., Hu, Y., Wieland, A., Im, S., Gavora, A., Medina, C. B., Freeman, G. J., Hashimoto, M., Reiner, S. L., & Ahmed, R. (2023). PD-1 blockade increases the self-renewal of stem-like CD8 T cells to compensate for their accelerated differentiation into effectors. Science Immunology, 8(86). https://doi.org/10.1126/sciimmunol.adg0539
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Matsumoto, R., Gray, J., Rybkina, K., Oppenheimer, H., Levy, L., Friedman, L. M., Khamaisi, M., Meng, W., Rosenfeld, A. M., Guyer, R. S., Bradley, M. C., Chen, D., Atkinson, M. A., Brusko, T. M., Brusko, M., Connors, T. J., Luning Prak, E. T., Hershberg, U., Sims, P. A., … Farber, D. L. (2023). Induction of bronchus-associated lymphoid tissue is an early life adaptation for promoting human B cell immunity. Nature Immunology, 24(8), 1370–1381. https://doi.org/10.1038/s41590-023-01557-3
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Zhang, Y., Zhang, W., Zhao, J., Ito, T., Jin, J., Aparicio, A. O., Zhou, J., Guichard, V., Fang, Y., Que, J., Urban, J. F., Hanna, J. H., Ghosh, S., Wu, X., Ding, L., Basu, U., & Huang, Y. (2023). m6A RNA modification regulates innate lymphoid cell responses in a lineage-specific manner. Nature Immunology, 24(8), 1256–1264. https://doi.org/10.1038/s41590-023-01548-4
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Shao, Z., Lee, B. J., Zhang, H., Lin, X., Li, C., Jiang, W., Chirathivat, N., Gershik, S., Shen, M. M., Baer, R., & Zha, S. (2023). Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner. Proceedings of the National Academy of Sciences, 120(31). https://doi.org/10.1073/pnas.2301972120
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Armstrong, J. F., Campo, B., Alexander, S. P. H., Arendse, L. B., Cheng, X., Davenport, A. P., Faccenda, E., Fidock, D. A., Godinez‐Macias, K. P., Harding, S. D., Kato, N., Lee, M. C. S., Luth, M. R., Mazitschek, R., Mittal, N., Niles, J. C., Okombo, J., Ottilie, S., Pasaje, C. F. A., … Davies, J. A. (2023). Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review 38. British Journal of Pharmacology, 180(15), 1899–1929. Portico. https://doi.org/10.1111/bph.16144
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Kornberg, A., Botella, T., Moon, C. S., Rao, S., Gelbs, J., Cheng, L., Miller, J., Bacarella, A. M., García-Vilas, J. A., Vargas, J., Yu, X., Krupska, I., Bush, E., Garcia-Carrasquillo, R., Lebwohl, B., Krishnareddy, S., Lewis, S., Green, P. H. R., Bhagat, G., … Han, A. (2023). Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease. Science Immunology, 8(85). https://doi.org/10.1126/sciimmunol.adf4312
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Ho, P., Melms, J. C., Rogava, M., Frangieh, C. J., Poźniak, J., Shah, S. B., Walsh, Z., Kyrysyuk, O., Amin, A. D., Caprio, L., Fullerton, B. T., Soni, R. K., Ager, C. R., Biermann, J., Wang, Y., Khosravi-Maharlooei, M., Zanetti, G., Mu, M., Fatima, H., … Izar, B. (2023). The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity. Cancer Cell, 41(7), 1207-1221.e12. https://doi.org/10.1016/j.ccell.2023.05.014
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Heidarian, M., Jensen, I. J., Kannan, S. K., Pewe, L. L., Hassert, M., Park, S., Xue, H.-H., Harty, J. T., & Badovinac, V. P. (2023). Sublethal whole-body irradiation induces permanent loss and dysfunction in pathogen-specific circulating memory CD8 T cell populations. Proceedings of the National Academy of Sciences, 120(27). https://doi.org/10.1073/pnas.2302785120
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Schvartzman, J.-M., Forsyth, G., Walch, H., Chatila, W., Taglialatela, A., Lee, B. J., Zhu, X., Gershik, S., Cimino, F. V., Santella, A., Menghrajani, K., Ciccia, A., Koche, R., Sánchez-Vega, F., Zha, S., & Thompson, C. B. (2023). Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination. Molecular Cell, 83(13), 2347-2356.e8. https://doi.org/10.1016/j.molcel.2023.05.026
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Chung, R., McKiernan, J., Arpaia, N., Marabelle, A., & Rouanne, M. (2023). Neo-Adjuvant immunotherapies: Bladder cancer as a platform for drug development targeting mucosal immunity. European Journal of Cancer, 187, 58–64. https://doi.org/10.1016/j.ejca.2023.03.037
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Matkovic Leko, I., Schneider, R. T., Thimraj, T. A., Schrode, N., Beitler, D., Liu, H.-Y., Beaumont, K., Chen, Y.-W., & Snoeck, H.-W. (2023). A distal lung organoid model to study interstitial lung disease, viral infection and human lung development. Nature Protocols, 18(7), 2283–2312. https://doi.org/10.1038/s41596-023-00827-6
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Kimble, M. T., Johnson, M. J., Nester, M. R., & Symington, L. S. (2023). Long-range DNA end resection supports homologous recombination by checkpoint activation rather than extensive homology generation. ELife, 12. CLOCKSS. https://doi.org/10.7554/elife.84322
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Su, R., Zeng, J., Marcink, T. C., Porotto, M., Moscona, A., & O’Shaughnessy, B. (2023). Host Cell Membrane Capture by the SARS-CoV-2 Spike Protein Fusion Intermediate. ACS Central Science, 9(6), 1213–1228. https://doi.org/10.1021/acscentsci.3c00158
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Zhu, Y., Jiang, W., Lee, B. J., Li, A., Gershik, S., & Zha, S. (2023). Phosphorylation of DNA-PKcs at the S2056 cluster ensures efficient and productive lymphocyte development in XLF-deficient mice. Proceedings of the National Academy of Sciences, 120(25). https://doi.org/10.1073/pnas.2221894120
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Singh, P., Gollapalli, K., Mangiola, S., Schranner, D., Yusuf, M. A., Chamoli, M., Shi, S. L., Lopes Bastos, B., Nair, T., Riermeier, A., Vayndorf, E. M., Wu, J. Z., Nilakhe, A., Nguyen, C. Q., Muir, M., Kiflezghi, M. G., Foulger, A., Junker, A., Devine, J., … Yadav, V. K. (2023). Taurine deficiency as a driver of aging. Science, 380(6649). https://doi.org/10.1126/science.abn9257
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Talaie, T., Wang, H., Kuo, W.-I., Danzl, N., Gulsen, M. R., Wolabaugh, A. N., Ding, X., Sykes, M., & Li, H. W. (2023). Origin, phenotype and autoimmune potential of T cells in human immune system mice receiving neonatal human thymus tissue. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1159341
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Burn Aschner, C., Muthuraman, K., Kucharska, I., Cui, H., Prieto, K., Nair, M. S., Wang, M., Huang, Y., Christie-Holmes, N., Poon, B., Lam, J., Sultana, A., Kozak, R., Mubareka, S., Rubinstein, J. L., Rujas, E., Treanor, B., Ho, D. D., Jetha, A., & Julien, J.-P. (2023). A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo. Science Translational Medicine, 15(697). https://doi.org/10.1126/scitranslmed.adf4549
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Ward, K. E., Christensen, P., Racklyeft, A., Dhingra, S. K., Chua, A. C. Y., Remmert, C., Suwanarusk, R., Matheson, J., Blackman, M. J., Kaneko, O., Kyle, D. E., Lee, M. C. S., Moon, R. W., Snounou, G., Rénia, L., Fidock, D. A., Russell, B., & Bifani, P. (2022). Integrative Genetic Manipulation of Plasmodium cynomolgi Reveals Multidrug Resistance-1 Y976F Associated With Increased In Vitro Susceptibility to Mefloquine. The Journal of Infectious Diseases, 227(10), 1121–1126. https://doi.org/10.1093/infdis/jiac469
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Deni, I., Stokes, B. H., Ward, K. E., Fairhurst, K. J., Pasaje, C. F. A., Yeo, T., Akbar, S., Park, H., Muir, R., Bick, D. S., Zhan, W., Zhang, H., Liu, Y. J., Ng, C. L., Kirkman, L. A., Almaliti, J., Gould, A. E., Duffey, M., O’Donoghue, A. J., … Fidock, D. A. (2023). Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome. Cell Chemical Biology, 30(5), 470-485.e6. https://doi.org/10.1016/j.chembiol.2023.03.002
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Cummings, M. J., Bakamutumaho, B., Jain, K., Price, A., Owor, N., Kayiwa, J., Namulondo, J., Byaruhanga, T., Muwanga, M., Nsereko, C., Nayiga, I., Kyebambe, S., Che, X., Sameroff, S., Tokarz, R., Wong, W., Postler, T. S., Larsen, M. H., Lipkin, W. I., … O’Donnell, M. R. (2023). Brief Report: Detection of Urine Lipoarabinomannan Is Associated With Proinflammatory Innate Immune Activation, Impaired Host Defense, and Organ Dysfunction in Adults With Severe HIV-Associated Tuberculosis in Uganda. JAIDS Journal of Acquired Immune Deficiency Syndromes, 93(1), 79–85. https://doi.org/10.1097/qai.0000000000003159
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Mugnier, M. R., & Ho, C.-M. (2023). mSphere of Influence: the Young Investigators in Parasitology Meeting—Investing in the Future of Our Scientific Community by Lifting Up and Connecting Junior Faculty. MSphere, 8(2). https://doi.org/10.1128/msphere.00615-22
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Rancan, C., Arias-Badia, M., Dogra, P., Chen, B., Aran, D., Yang, H., Luong, D., Ilano, A., Li, J., Chang, H., Kwek, S. S., Zhang, L., Lanier, L. L., Meng, M. V., Farber, D. L., & Fong, L. (2023). Exhausted intratumoral Vδ2− γδ T cells in human kidney cancer retain effector function. Nature Immunology, 24(4), 612–624. https://doi.org/10.1038/s41590-023-01448-7
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Girard, A., Dercle, L., Vila-Reyes, H., Schwartz, L. H., Girma, A., Bertaux, M., Radulescu, C., Lebret, T., Delcroix, O., & Rouanne, M. (2022). A machine-learning-based combination of criteria to detect bladder cancer lymph node metastasis on [18F]FDG PET/CT: a pathology-controlled study. European Radiology, 33(4), 2821–2829. https://doi.org/10.1007/s00330-022-09270-9
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Shin, A. E., Tesfagiorgis, Y., Larsen, F., Derouet, M., Zeng, P. Y. F., Good, H. J., Zhang, L., Rubinstein, M. R., Han, Y. W., Kerfoot, S. M., Nichols, A. C., Hayakawa, Y., Howlett, C. J., Wang, T. C., & Asfaha, S. (2023). F4/80+Ly6Chigh Macrophages Lead to Cell Plasticity and Cancer Initiation in Colitis. Gastroenterology, 164(4), 593-609.e13. https://doi.org/10.1053/j.gastro.2023.01.002
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