Center for Stem Cell Therapies

Displaying 1 - 27 of 27CSV
Pezet, M. G., Torres, J. A., Thimraj, T. A., Matkovic, I., Schrode, N., Murray, J. W., Saqi, A., Beaumont, K. G., & Snoeck, H.-W. (2025). Human respiratory airway progenitors derived from pluripotent cells generate alveolar epithelial cells and model pulmonary fibrosis. Nature Biotechnology. https://doi.org/10.1038/s41587-025-02569-0
Publication Date
Yuan, F., Yang, J., Ma, F., Hu, Z., Malik, V., Zang, R., Li, D., Shi, X., Huang, X., Zhou, H., & Wang, J. (2025). Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57165-2
Publication Date
Hong, J., Sui, P., Li, Y., Xu, K. Y., Lee, J.-H., Wang, J., Chen, S., Zhang, P., Wingate, N., Noor, A., Yuan, Y., Hromas, R., Zhou, H., Hamamoto, K., Su, R., Yin, C. C., Ye, F., Quesada, A. E., Chen, J., … Xu, M. (2025). PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1. Cell Stem Cell. https://doi.org/10.1016/j.stem.2025.01.010
Publication Date
Yan, X.-Z., Peng, J., Liu, Y.-Q., Fan, R.-N., Ni, X.-Y., Gong, L., Zhang, D.-N., Huang, X., Tan, S.-H., & Wang, H.-L. (2025). Mixed exposure to PFOA and PFOS induces oocyte apoptosis and subfertility in mice by activating the Hippo signaling pathway. Reproductive Toxicology, 132, 108829. https://doi.org/10.1016/j.reprotox.2024.108829
Publication Date
Flury, A., Aljayousi, L., Park, H.-J., Khakpour, M., Mechler, J., Aziz, S., McGrath, J. D., Deme, P., Sandberg, C., González Ibáñez, F., Braniff, O., Ngo, T., Smith, S., Velez, M., Ramirez, D. M., Avnon-Klein, D., Murray, J. W., Liu, J., Parent, M., … Ayata, P. (2024). A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion. Neuron. https://doi.org/10.1016/j.neuron.2024.11.018
Publication Date
Gu, J., Iyer, A., Wesley, B., Taglialatela, A., Leuzzi, G., Hangai, S., Decker, A., Gu, R., Klickstein, N., Shuai, Y., Jankovic, K., Parker-Burns, L., Jin, Y., Zhang, J. Y., Hong, J., Niu, X., Costa, J. A., Pezet, M. G., Chou, J., … Gaublomme, J. T. (2024). Mapping multimodal phenotypes to perturbations in cells and tissue with CRISPRmap. Nature Biotechnology. https://doi.org/10.1038/s41587-024-02386-x
Publication Date
Ngule, C., Shi, R., Ren, X., Jia, H., Oyelami, F., Li, D., Park, Y., Kim, J., Hemati, H., Zhang, Y., Xiong, X., Shinkle, A., Vanderford, N. L., Bachert, S., Zhou, B. P., Wang, J., Song, J., Liu, X., & Yang, J.-M. (2024). NAC1 promotes stemness and regulates myeloid-derived cell status in triple-negative breast cancer. Molecular Cancer, 23(1). https://doi.org/10.1186/s12943-024-02102-y
Publication Date
Shimizu, D., Miura, A., & Mori, M. (2024). The perspective for next-generation lung replacement therapies: functional whole lung generation by blastocyst complementation. Current Opinion in Organ Transplantation. https://doi.org/10.1097/mot.0000000000001169
Publication Date
Tanaka, J., Miura, A., Shimamura, Y., Hwang, Y., Shimizu, D., Kondo, Y., Sawada, A., Sarmah, H., Ninish, Z., Mishima, K., & Mori, M. (2024). Generation of salivary glands derived from pluripotent stem cells via conditional blastocyst complementation. Cell Reports, 43(6), 114340. https://doi.org/10.1016/j.celrep.2024.114340
Publication Date
Sarmah, H., Sawada, A., Hwang, Y., Miura, A., Shimamura, Y., Tanaka, J., Yamada, K., & Mori, M. (2023). Towards human organ generation using interspecies blastocyst complementation: Challenges and perspectives for therapy. Frontiers in Cell and Developmental Biology, 11. https://doi.org/10.3389/fcell.2023.1070560
Publication Date
Huang, X., Balmer, S., Lyu, C., Xiang, Y., Malik, V., Wang, H., Zhang, Y., Cai, B., Xie, W., Hadjantonakis, A.-K., Zhou, H., & Wang, J. (2024). ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1. Developmental Cell, 59(4), 465-481.e6. https://doi.org/10.1016/j.devcel.2023.12.018
Publication Date
MacCarthy, C. M., Wu, G., Malik, V., Menuchin-Lasowski, Y., Velychko, T., Keshet, G., Fan, R., Bedzhov, I., Church, G. M., Jauch, R., Cojocaru, V., Schöler, H. R., & Velychko, S. (2024). Highly cooperative chimeric super-SOX induces naive pluripotency across species. Cell Stem Cell, 31(1), 127-147.e9. https://doi.org/10.1016/j.stem.2023.11.010
Publication Date
Bankoti, K., Wang, W., Amonkar, G. M., Xiong, L., Shui, J. E., Zhao, C., Van, E., Mwase, C., Park, J.-A., Mou, H., Fang, Y., Que, J., Bai, Y., Lerou, P. H., & Ai, X. (2024). Airway Basal Stem Cells in COVID-19 Exhibit a Proinflammatory Signature and Impaired Mucocililary Differentiation. American Journal of Respiratory Cell and Molecular Biology, 70(1), 26–38. https://doi.org/10.1165/rcmb.2023-0104oc
Publication Date
Tsuji, M., Nair, M. S., Masuda, K., Castagna, C., Chong, Z., Darling, T. L., Seehra, K., Hwang, Y., Ribeiro, Á. L., Ferreira, G. M., Corredor, L., Coelho-dos-Reis, J. G. A., Tsuji, Y., Mori, M., Boon, A. C. M., Diamond, M. S., Huang, Y., & Ho, D. D. (2023). An immunostimulatory glycolipid that blocks SARS-CoV-2, RSV, and influenza infections in vivo. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-39738-1
Publication Date
Miura, A., Sarmah, H., Tanaka, J., Hwang, Y., Sawada, A., Shimamura, Y., Otoshi, T., Kondo, Y., Fang, Y., Shimizu, D., Ninish, Z., Suer, J. L., Dubois, N. C., Davis, J., Toyooka, S., Wu, J., Que, J., Hawkins, F. J., Lin, C.-S., & Mori, M. (2023). Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung. ELife, 12. CLOCKSS. https://doi.org/10.7554/elife.86105
Publication Date
Daniel, J. A., Elizarova, S., Shaib, A. H., Chouaib, A. A., Magnussen, H. M., Wang, J., Brose, N., Rhee, J., & Tirard, M. (2023). An intellectual-disability-associated mutation of the transcriptional regulator NACC1 impairs glutamatergic neurotransmission. Frontiers in Molecular Neuroscience, 16. https://doi.org/10.3389/fnmol.2023.1115880
Publication Date
Zhang, Y., Zhang, W., Zhao, J., Ito, T., Jin, J., Aparicio, A. O., Zhou, J., Guichard, V., Fang, Y., Que, J., Urban, J. F., Hanna, J. H., Ghosh, S., Wu, X., Ding, L., Basu, U., & Huang, Y. (2023). m6A RNA modification regulates innate lymphoid cell responses in a lineage-specific manner. Nature Immunology, 24(8), 1256–1264. https://doi.org/10.1038/s41590-023-01548-4
Publication Date
Kornberg, A., Botella, T., Moon, C. S., Rao, S., Gelbs, J., Cheng, L., Miller, J., Bacarella, A. M., García-Vilas, J. A., Vargas, J., Yu, X., Krupska, I., Bush, E., Garcia-Carrasquillo, R., Lebwohl, B., Krishnareddy, S., Lewis, S., Green, P. H. R., Bhagat, G., … Han, A. (2023). Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease. Science Immunology, 8(85). https://doi.org/10.1126/sciimmunol.adf4312
Publication Date
Gwon, K., Lee, S., Kim, Y., Choi, J., Kim, S., Kim, S.-J., Hong, H. J., Hwang, Y., Mori, M., & Lee, D. N. (2023). Construction of a bioactive copper-based metal organic framework-embedded dual-crosslinked alginate hydrogel for antimicrobial applications. International Journal of Biological Macromolecules, 242, 124840. https://doi.org/10.1016/j.ijbiomac.2023.124840
Publication Date
Matkovic Leko, I., Schneider, R. T., Thimraj, T. A., Schrode, N., Beitler, D., Liu, H.-Y., Beaumont, K., Chen, Y.-W., & Snoeck, H.-W. (2023). A distal lung organoid model to study interstitial lung disease, viral infection and human lung development. Nature Protocols, 18(7), 2283–2312. https://doi.org/10.1038/s41596-023-00827-6
Publication Date
Chen, Q., Weng, K., Lin, M., Jiang, M., Fang, Y., Chung, S. S. W., Huang, X., Zhong, Q., Liu, Z., Huang, Z., Lin, J., Li, P., El-Rifai, W., Zaika, A., Li, H., Rustgi, A. K., Nakagawa, H., Abrams, J. A., Wang, T. C., … Que, J. (2023). SOX9 Modulates the Transformation of Gastric Stem Cells Through Biased Symmetric Cell Division. Gastroenterology, 164(7), 1119-1136.e12. https://doi.org/10.1053/j.gastro.2023.01.037
Publication Date