Systematic dissection of coordinated stromal remodeling identifies Sox10+ glial cells as a therapeutic target in myelofibrosis

Sarkaria, S. M., Zhou, J., Bao, S., Zhao, W., Fang, Y., Que, J., Bhagat, G., Zhang, C., & Ding, L. (2023). Systematic dissection of coordinated stromal remodeling identifies Sox10 glial cells as a therapeutic target in myelofibrosis. Cell Stem Cell, 30(6), 832-850.e6. https://doi.org/10.1016/j.stem.2023.05.002
Authors:
Shawn M Sarkaria
Junsong Zhou
Suying Bao
Wenqi Zhao
Yinshan Fang
Jianwen Que
Govind Bhagat
Chaolin Zhang
Lei Ding
Affiliated Authors:
Shawn M Sarkaria
Junsong Zhou
Suying Bao
Wenqi Zhao
Yinshan Fang
Jianwen Que
Govind Bhagat
Chaolin Zhang
Lei Ding
Columbia Affiliation:
Subjects:
Molecular Pathogenesis of Myeloproliferative Disorders (OpenAlex Topic)
Acute Myeloid Leukemia (OpenAlex Topic)
Platelet Disorders and Thrombosis Mechanisms (OpenAlex Topic)
Primary Myelofibrosis (MeSH)
Author Keywords:
gli1
glial cells
hematopoietic stem cells
lepr
lineage tracing
mesenchymal stromal cells
microenvironmental niche
myelofibrosis
single-cell rna sequencing
elink
Publication Type:
Article
Unique ID:
10.1016/j.stem.2023.05.002
PMID:
37267917
DOI:
10.1016/j.stem.2023.05.002
Journal:
Cell Stem Cell
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
View OpenAlex Record

Record Created: