Su, Z., Kon, N., Yi, J., Zhao, H., Zhang, W., Tang, Q., Li, H., Kobayashi, H., Li, Z., Duan, S., Liu, Y., Olive, K. P., Zhang, Z., Honig, B., Manfredi, J. J., Rustgi, A. K., & Gu, W. (2023). Specific regulation of BACH1 by the hotspot mutant p53R175H reveals a distinct gain-of-function mechanism. Nature Cancer, 4(4), 564–581. https://doi.org/10.1038/s43018-023-00532-z

Girard, A., Dercle, L., Vila-Reyes, H., Schwartz, L. H., Girma, A., Bertaux, M., Radulescu, C., Lebret, T., Delcroix, O., & Rouanne, M. (2022). A machine-learning-based combination of criteria to detect bladder cancer lymph node metastasis on [18F]FDG PET/CT: a pathology-controlled study. European Radiology, 33(4), 2821–2829. https://doi.org/10.1007/s00330-022-09270-9

Langelier, M.-F., Lin, X., Zha, S., & Pascal, J. M. (2023). Clinical PARP inhibitors allosterically induce PARP2 retention on DNA. Science Advances, 9(12). https://doi.org/10.1126/sciadv.adf7175

Dadonaite, B., Crawford, K. H. D., Radford, C. E., Farrell, A. G., Yu, T. C., Hannon, W. W., Zhou, P., Andrabi, R., Burton, D. R., Liu, L., Ho, D. D., Chu, H. Y., Neher, R. A., & Bloom, J. D. (2023). A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike. Cell, 186(6), 1263-1278.e20. https://doi.org/10.1016/j.cell.2023.02.001

Savage, T. M., Vincent, R. L., Rae, S. S., Huang, L. H., Ahn, A., Pu, K., Li, F., de los Santos-Alexis, K., Coker, C., Danino, T., & Arpaia, N. (2023). Chemokines expressed by engineered bacteria recruit and orchestrate antitumor immunity. Science Advances, 9(10). https://doi.org/10.1126/sciadv.adc9436

Ashton, T. D., Dans, M. G., Favuzza, P., Ngo, A., Lehane, A. M., Zhang, X., Qiu, D., Chandra Maity, B., De, N., Schindler, K. A., Yeo, T., Park, H., Uhlemann, A.-C., Churchyard, A., Baum, J., Fidock, D. A., Jarman, K. E., Lowes, K. N., Baud, D., … Sleebs, B. E. (2023). Optimization of 2,3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4. Journal of Medicinal Chemistry, 66(5), 3540–3565. https://doi.org/10.1021/acs.jmedchem.2c02092

Istvan, E. S., Guerra, F., Abraham, M., Huang, K.-S., Rocamora, F., Zhao, H., Xu, L., Pasaje, C., Kumpornsin, K., Luth, M. R., Cui, H., Yang, T., Palomo Diaz, S., Gomez-Lorenzo, M. G., Qahash, T., Mittal, N., Ottilie, S., Niles, J., Lee, M. C. S., … Winzeler, E. A. (2023). Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target. Science Translational Medicine, 15(686). https://doi.org/10.1126/scitranslmed.adc9249

Kaiser, K. A., Loffredo, L. F., Santos-Alexis, K. de los, Ringham, O. R., & Arpaia, N. (2022). Regulation of the alveolar regenerative niche by amphiregulin-producing regulatory T cells. Journal of Experimental Medicine, 220(3). https://doi.org/10.1084/jem.20221462

Sykes, M., Chandran, S., Kawai, T., Levitsky, J., Mapara, M., Mathew, J., Thomson, A., & Yamada, K. (2023). Meeting Report: The Fifth International Samuel Strober Workshop on Clinical Immune Tolerance. Transplantation, 107(3), 564–569. https://doi.org/10.1097/tp.0000000000004473

DiLorenzo, M. P., Farooqi, K. M., Shah, A. M., Channing, A., Harrington, J. K., Connors, T. J., Martirosyan, K., Krishnan, U. S., Ferris, A., Weller, R. J., Farber, D. L., Milner, J. D., Gorelik, M., Rosenzweig, E. B., & Anderson, B. R. (2022). Ventricular function and tissue characterization by cardiac magnetic resonance imaging following hospitalization for multisystem inflammatory syndrome in children: a prospective study. Pediatric Radiology, 53(3), 394–403. https://doi.org/10.1007/s00247-022-05521-5

Rankin, L. C., Kaiser, K. A., de los Santos-Alexis, K., Park, H., Uhlemann, A.-C., Gray, D. H. D., & Arpaia, N. (2023). Dietary tryptophan deficiency promotes gut RORγt+ Treg cells at the expense of Gata3+ Treg cells and alters commensal microbiota metabolism. Cell Reports, 42(3), 112135. https://doi.org/10.1016/j.celrep.2023.112135

Miholjcic, T. B. S., Halse, H., Bonvalet, M., Bigorgne, A., Rouanne, M., Dercle, L., Shankar, V., & Marabelle, A. (2023). Rationale for LDH-targeted cancer immunotherapy. European Journal of Cancer, 181, 166–178. https://doi.org/10.1016/j.ejca.2022.11.032

Dworkin, J. (2023). Understanding the Stringent Response: Experimental Context Matters. MBio, 14(1). https://doi.org/10.1128/mbio.03404-22

Fraga de Andrade, I., Johnson, K. D., Mehta, C., Dewey, C. N., Basu, U., & Bresnick, E. H. (2023). RNA-regulatory exosome complex suppresses an apoptotic program to confer erythroid progenitor cell survival in vivo. Blood Advances, 7(4), 586–601. https://doi.org/10.1182/bloodadvances.2022008481

Feaga, H. A., Hong, H.-R., Prince, C. R., Rankin, A., Buskirk, A. R., & Dworkin, J. (2023). Elongation Factor P Is Important for Sporulation Initiation. Journal of Bacteriology, 205(2). https://doi.org/10.1128/jb.00370-22

Marcink, T. C., Zipursky, G., Cheng, W., Stearns, K., Stenglein, S., Golub, K., Cohen, F., Bovier, F., Pfalmer, D., Greninger, A. L., Porotto, M., des Georges, A., & Moscona, A. (2023). Subnanometer structure of an enveloped virus fusion complex on viral surface reveals new entry mechanisms. Science Advances, 9(6). https://doi.org/10.1126/sciadv.ade2727

Jin, D., Zhu, Y., Schubert, H. L., Goff, S. P., & Musier-Forsyth, K. (2023). HIV-1 Gag Binds the Multi-Aminoacyl-tRNA Synthetase Complex via the EPRS Subunit. Viruses, 15(2), 474. https://doi.org/10.3390/v15020474

Kim, C., Wang, X.-D., Liu, Z., Zha, S., & Yu, Y. (2022). Targeting Scaffolding Functions of Enzymes Using PROTAC Approaches. Biochemistry, 62(3), 561–563. https://doi.org/10.1021/acs.biochem.2c00366

Maniar, R., Wang, P. H., Washburn, R. S., Kratchmarov, R., Coley, S. M., Saqi, A., Pan, S. S., Hu, J., Shu, C. A., Rizvi, N. A., Henick, B. S., & Reiner, S. L. (2022). Self-Renewing CD8+ T-cell Abundance in Blood Associates with Response to Immunotherapy. Cancer Immunology Research, 11(2), 164–170. https://doi.org/10.1158/2326-6066.cir-22-0524

Poon, M. M. L., Caron, D. P., Wang, Z., Wells, S. B., Chen, D., Meng, W., Szabo, P. A., Lam, N., Kubota, M., Matsumoto, R., Rahman, A., Luning Prak, E. T., Shen, Y., Sims, P. A., & Farber, D. L. (2023). Tissue adaptation and clonal segregation of human memory T cells in barrier sites. Nature Immunology, 24(2), 309–319. https://doi.org/10.1038/s41590-022-01395-9

Cummings, M. J., Bakamutumaho, B., Price, A., Owor, N., Kayiwa, J., Namulondo, J., Byaruhanga, T., Jain, K., Postler, T. S., Muwanga, M., Nsereko, C., Nayiga, I., Kyebambe, S., Che, X., Sameroff, S., Tokarz, R., Shah, S. S., Larsen, M. H., Lipkin, W. I., … O’Donnell, M. R. (2022). HIV infection drives pro-inflammatory immunothrombotic pathway activation and organ dysfunction among adults with sepsis in Uganda. AIDS, 37(2), 233–245. https://doi.org/10.1097/qad.0000000000003410

Wang, Q., Iketani, S., Li, Z., Liu, L., Guo, Y., Huang, Y., Bowen, A. D., Liu, M., Wang, M., Yu, J., Valdez, R., Lauring, A. S., Sheng, Z., Wang, H. H., Gordon, A., Liu, L., & Ho, D. D. (2023). Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants. Cell, 186(2), 279-286.e8. https://doi.org/10.1016/j.cell.2022.12.018

Huemer, M., Mairpady Shambat, S., Hertegonne, S., Bergada-Pijuan, J., Chang, C.-C., Pereira, S., Gómez-Mejia, A., Van Gestel, L., Bär, J., Vulin, C., Pfammatter, S., Stinear, T. P., Monk, I. R., Dworkin, J., & Zinkernagel, A. S. (2023). Serine-threonine phosphoregulation by PknB and Stp contributes to quiescence and antibiotic tolerance in Staphylococcus aureus. Science Signaling, 16(766). https://doi.org/10.1126/scisignal.abj8194

Fu, J., Rust, D., Fang, Z., Jiao, W., Lagana, S., Batal, I., Chen, B., Merl, S., Jones, R., Sykes, M., & Weiner, J. (2022). T cell repertoire profiling in allografts and native tissues in recipients with COVID–19 after solid organ transplantation: Insight into T cell–mediated allograft protection from viral infection. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.1056703

Zagelbaum, J., Schooley, A., Zhao, J., Schrank, B. R., Callen, E., Zha, S., Gottesman, M. E., Nussenzweig, A., Rabadan, R., Dekker, J., & Gautier, J. (2022). Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature Structural & Molecular Biology, 30(1), 99–106. https://doi.org/10.1038/s41594-022-00893-6

Ding, L., Gao, L., Lee, H., & Goodman, J. (2023). 3050 – AN EPITRANSCRIPTOMIC PROGRAM DISTINGUISHES HEMATOPOIETIC STEM CELL NICHE GENERATION FROM MAINTENANCE. Experimental Hematology, 124, S75. https://doi.org/10.1016/j.exphem.2023.06.157

Iketani, S., Mohri, H., Culbertson, B., Hong, S. J., Duan, Y., Luck, M. I., Annavajhala, M. K., Guo, Y., Sheng, Z., Uhlemann, A.-C., Goff, S. P., Sabo, Y., Yang, H., Chavez, A., & Ho, D. D. (2022). Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir. Nature, 613(7944), 558–564. https://doi.org/10.1038/s41586-022-05514-2

Bukhari, S., Henick, B. S., Winchester, R. J., Lerrer, S., Adam, K., Gartshteyn, Y., Maniar, R., Lin, Z., Khodadadi-Jamayran, A., Tsirigos, A., Salvatore, M. M., Lagos, G. G., Reiner, S. L., Dallos, M. C., Mathew, M., Rizvi, N. A., & Mor, A. (2023). Single-cell RNA sequencing reveals distinct T cell populations in immune-related adverse events of checkpoint inhibitors. Cell Reports Medicine, 4(1), 100868. https://doi.org/10.1016/j.xcrm.2022.100868

Gartrell, R. D., Enzler, T., Kim, P. S., Fullerton, B. T., Fazlollahi, L., Chen, A. X., Minns, H. E., Perni, S., Weisberg, S. P., Rizk, E. M., Wang, S., Oh, E. J., Guo, X. V., Chiuzan, C., Manji, G. A., Bates, S. E., Chabot, J., Schrope, B., Kluger, M., … Saenger, Y. M. (2022). Neoadjuvant chemoradiation alters the immune microenvironment in pancreatic ductal adenocarcinoma. OncoImmunology, 11(1). https://doi.org/10.1080/2162402x.2022.2066767

Annavajhala, M. K., Kelly, N. E., Geng, W., Ferguson, S. A., Giddins, M. J., Grohs, E. C., Hill-Ricciuti, A., Green, D. A., Saiman, L., & Uhlemann, A.-C. (2022). Genomic and Epidemiological Features of Two Dominant Methicillin-Susceptible Staphylococcus aureus Clones from a Neonatal Intensive Care Unit Surveillance Effort. MSphere, 7(6). https://doi.org/10.1128/msphere.00409-22

Nelson, T. M., Ghosh, S., & Postler, T. S. (2022). L-RAPiT: A Cloud-Based Computing Pipeline for the Analysis of Long-Read RNA Sequencing Data. International Journal of Molecular Sciences, 23(24), 15851. https://doi.org/10.3390/ijms232415851

Liu, H., Li, P., Zhang, S., Xiang, J., Yang, R., Liu, J., Shafiquzzaman, M., Biswas, S., Wei, Z., Zhang, Z., Zhou, X., Yin, F., Xie, Y., Goff, S. P., Chen, L., & Li, B. (2022). Prrx1 marks stem cells for bone, white adipose tissue and dermis in adult mice. Nature Genetics, 54(12), 1946–1958. https://doi.org/10.1038/s41588-022-01227-4

Hilmi, M., Naoun, N., Boilève, A., Géraud, A., Bayle, A., Pagès, A., Aupomerol, M., Rouanne, M., Madec, F.-X., Pommeret, F., Massard, C., Baldini, C., Scotté, F., & Champiat, S. (2022). Evaluation of supportive care needs, sexuality and quality of life in phase 1 trials: a prospective monocentric study. Supportive Care in Cancer, 30(12), 9841–9849. https://doi.org/10.1007/s00520-022-07407-6

Lin, C., Yang, Q., Guo, D., Xie, J., Yang, Y.-S., Chaugule, S., DeSouza, N., Oh, W.-T., Li, R., Chen, Z., John, A. A., Qiu, Q., Zhu, L. J., Greenblatt, M. B., Ghosh, S., Li, S., Gao, G., Haynes, C., Emerson, C. P., & Shim, J.-H. (2022). Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34694-8

Reynard, O., Gonzalez, C., Dumont, C., Iampietro, M., Ferren, M., Le Guellec, S., Laurie, L., Mathieu, C., Carpentier, G., Roseau, G., Bovier, F. T., Zhu, Y., Le Pennec, D., Montharu, J., Addetia, A., Greninger, A. L., Alabi, C. A., Brisebard, E., Moscona, A., … Horvat, B. (2022). Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33832-6

Liu, H., Iketani, S., Zask, A., Khanizeman, N., Bednarova, E., Forouhar, F., Fowler, B., Hong, S. J., Mohri, H., Nair, M. S., Huang, Y., Tay, N. E. S., Lee, S., Karan, C., Resnick, S. J., Quinn, C., Li, W., Shion, H., Xia, X., … Stockwell, B. R. (2022). Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29413-2

Winans, S., Yu, H. J., de los Santos, K., Wang, G. Z., KewalRamani, V. N., & Goff, S. P. (2022). A point mutation in HIV-1 integrase redirects proviral integration into centromeric repeats. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29097-8

Effect of air pollution on the human immune system. (2022). Nature Medicine, 28(12), 2482–2483. https://doi.org/10.1038/s41591-022-02093-7

Postler, T. S., Rubino, L., Adriaenssens, E. M., Dutilh, B. E., Harrach, B., Junglen, S., Kropinski, A. M., Krupovic, M., Wada, J., Crane, A., Kuhn, J. H., Mushegian, A., Rūmnieks, J., Sabanadzovic, S., Simmonds, P., Varsani, A., Zerbini, F. M., Callanan, J., Draper, L. A., … Stockdale, S. R. (2022). Guidance for creating individual and batch latinized binomial virus species names. Journal of General Virology, 103(12). https://doi.org/10.1099/jgv.0.001800

Kuhn, J. H., Adkins, S., Alkhovsky, S. V., Avšič-Županc, T., Ayllón, M. A., Bahl, J., Balkema-Buschmann, A., Ballinger, M. J., Bandte, M., Beer, M., Bejerman, N., Bergeron, É., Biedenkopf, N., Bigarré, L., Blair, C. D., Blasdell, K. R., Bradfute, S. B., Briese, T., Brown, P. A., … Økland, A. L. (2022). 2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Archives of Virology, 167(12), 2857–2906. https://doi.org/10.1007/s00705-022-05546-z

Sykes, M., & Sachs, D. H. (2022). Progress in xenotransplantation: overcoming immune barriers. Nature Reviews Nephrology, 18(12), 745–761. https://doi.org/10.1038/s41581-022-00624-6

Wicht, K. J., Small-Saunders, J. L., Hagenah, L. M., Mok, S., & Fidock, D. A. (2022). Mutant PfCRT Can Mediate Piperaquine Resistance in African Plasmodium falciparum With Reduced Fitness and Increased Susceptibility to Other Antimalarials. The Journal of Infectious Diseases, 226(11), 2021–2029. https://doi.org/10.1093/infdis/jiac365

Fourati, S., Tomalin, L. E., Mulè, M. P., Chawla, D. G., Gerritsen, B., Rychkov, D., Henrich, E., Miller, H. E. R., Hagan, T., Diray-Arce, J., Dunn, P., Deckhut-Augustine, A., Haddad, E. K., Hafler, D. A., Harris, E., Farber, D., McElrath, J., Montgomery, R. R., … Sékaly, R.-P. (2022). Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination. Nature Immunology, 23(12), 1777–1787. https://doi.org/10.1038/s41590-022-01329-5

de Vries, L. E., Jansen, P. A. M., Barcelo, C., Munro, J., Verhoef, J. M. J., Pasaje, C. F. A., Rubiano, K., Striepen, J., Abla, N., Berning, L., Bolscher, J. M., Demarta-Gatsi, C., Henderson, R. W. M., Huijs, T., Koolen, K. M. J., Tumwebaze, P. K., Yeo, T., Aguiar, A. C. C., Angulo-Barturen, I., … Dechering, K. J. (2022). Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29688-5

Li, Y., Wu, Y., Federzoni, E. A., Wang, X., Dharmawan, A., Hu, X., Wang, H., Hawley, R. J., Stevens, S., Sykes, M., & Yang, Y.-G. (2022). CD47 cross-dressing by extracellular vesicles expressing CD47 inhibits phagocytosis without transmitting cell death signals. ELife, 11. CLOCKSS. https://doi.org/10.7554/elife.73677

Ural, B. B., Caron, D. P., Dogra, P., Wells, S. B., Szabo, P. A., Granot, T., Senda, T., Poon, M. M. L., Lam, N., Thapa, P., Lee, Y. S., Kubota, M., Matsumoto, R., & Farber, D. L. (2022). Inhaled particulate accumulation with age impairs immune function and architecture in human lung lymph nodes. Nature Medicine, 28(12), 2622–2632. https://doi.org/10.1038/s41591-022-02073-x

Wang, P., Casner, R. G., Nair, M. S., Yu, J., Guo, Y., Wang, M., Chan, J. F.-W., Cerutti, G., Iketani, S., Liu, L., Sheng, Z., Chen, Z., Yuen, K.-Y., Kwong, P. D., Huang, Y., Shapiro, L., & Ho, D. D. (2021). A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses. Emerging Microbes & Infections, 11(1), 147–157. https://doi.org/10.1080/22221751.2021.2011623

Hagan, T., Gerritsen, B., Tomalin, L. E., Fourati, S., Mulè, M. P., Chawla, D. G., Rychkov, D., Henrich, E., Miller, H. E. R., Diray-Arce, J., Dunn, P., Lee, A., Deckhut-Augustine, A., Gottardo, R., Haddad, E. K., Hafler, D. A., Harris, E., Farber, D., … Pulendran, B. (2022). Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses. Nature Immunology, 23(12), 1788–1798. https://doi.org/10.1038/s41590-022-01328-6

Geis, F. K., Kelenis, D. P., & Goff, S. P. (2022). Two lymphoid cell lines potently silence unintegrated HIV-1 DNAs. Retrovirology, 19(1). https://doi.org/10.1186/s12977-022-00602-7

Marie, L., & Symington, L. S. (2022). Mechanism for inverted-repeat recombination induced by a replication fork barrier. Nature Communications, 13(1). https://doi.org/10.1038/s41467-021-27443-w