Department of Genetics and Development

Displaying 251 - 300 of 413CSV
Fernández, E. C., Wang, J., Zhang, X., Wei, H.-J., Minns, H., Griffin, A., Obradovic, A., Vlahos, L., Martins, T., Becker, P., Crawford, J., Gartrell, R., Szalontay, L., Zacharoulis, S., Zhang, Z., Wechsler-Reya, R., Wu, C.-C., Califano, A., & Pavisic, J. (2023). DIPG-49. A SYSTEMS BIOLOGY APPROACH TO DEFINING AND TARGETING CELL STATE-SPECIFIC MASTER REGULATOR DEPENDENCIES IN DIFFUSE MIDLINE GLIOMA. Neuro-Oncology, 25(Supplement_1), i24–i24. https://doi.org/10.1093/neuonc/noad073.096
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Chen, Q., Weng, K., Lin, M., Jiang, M., Fang, Y., Chung, S. S. W., Huang, X., Zhong, Q., Liu, Z., Huang, Z., Lin, J., Li, P., El-Rifai, W., Zaika, A., Li, H., Rustgi, A. K., Nakagawa, H., Abrams, J. A., Wang, T. C., … Que, J. (2023). SOX9 Modulates the Transformation of Gastric Stem Cells Through Biased Symmetric Cell Division. Gastroenterology, 164(7), 1119-1136.e12. https://doi.org/10.1053/j.gastro.2023.01.037
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Tshering, L. F., Luo, F., Russ, S., Szenk, M., Rubel, D., Tutuska, K., Rail, J. G., Balázsi, G., Shen, M. M., & Talos, F. (2023). Immune mechanisms shape the clonal landscape during early progression of prostate cancer. Developmental Cell, 58(12), 1071-1086.e8. https://doi.org/10.1016/j.devcel.2023.04.010
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Aftab, A., Ali, M., Yousaf, Z., Binjawhar, D. N., Hyder, S., Aftab, Z., Maqbool, Z., Shahzadi, Z., Eldin, S. M., Iqbal, R., & Ali, I. (2023). Shelf‐life extension of Fragaria × ananassa Duch. using selenium nanoparticles synthesized from Cassia fistula Linn. leaves. Food Science & Nutrition, 11(6), 3464–3484. Portico. https://doi.org/10.1002/fsn3.3336
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Ahimaz, P., Foltz, J. C., Ross, M. J., Florido, M. E., Sebastin, M., & Yu, J. E. (2023). Exploring the role of genetic counselors in immunology: A study of immunologist and allergist perspectives. The Journal of Allergy and Clinical Immunology: In Practice, 11(6), 1939-1942.e2. https://doi.org/10.1016/j.jaip.2023.01.050
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Colombo, S., Reddy, H. P., Petri, S., Williams, D. J., Shalomov, B., Dhindsa, R. S., Gelfman, S., Krizay, D., Bera, A. K., Yang, M., Peng, Y., Makinson, C. D., Boland, M. J., Frankel, W. N., Goldstein, D. B., & Dascal, N. (2023). Epilepsy in a mouse model of GNB1 encephalopathy arises from altered potassium (GIRK) channel signaling and is alleviated by a GIRK inhibitor. Frontiers in Cellular Neuroscience, 17. https://doi.org/10.3389/fncel.2023.1175895
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Kama, R., Javed, Q., Bo, Y., Imran, M. A., Filimban, F. Z., Li, Z., Nong, X., Diatta, S., Ren, G., Eldin, S. M., Iqbal, R., Ali, I., Iqbal, J., & Sun, J. (2023). Identity and Diversity of Invasive Plant Affecting the Growth of Native Lactuca indica. ACS Omega, 8(20), 17983–17991. https://doi.org/10.1021/acsomega.3c01139
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Ilyas, M., Ali, I., Nasser Binjawhar, D., Ullah, S., Eldin, S. M., Ali, B., Iqbal, R., Bokhari, S. H. A., & Mahmood, T. (2023). Molecular Characterization of Germin-like Protein Genes in Zea mays (ZmGLPs) Using Various In Silico Approaches. ACS Omega, 8(18), 16327–16344. https://doi.org/10.1021/acsomega.3c01104
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Sun, X.-L., Chen, Z.-H., Guo, X., Wang, J., Ge, M., Wong, S. Z. H., Wang, T., Li, S., Yao, M., Johnston, L. A., & Wu, Q.-F. (2023). Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development. Developmental Cell, 58(9), 744-759.e11. https://doi.org/10.1016/j.devcel.2023.03.016
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Greenstein, V. C., Castillejos, D. S., Tsang, S. H., Lee, W., Sparrow, J. R., Allikmets, R., Birch, D. G., & Hood, D. C. (2023). Monitoring Lesion Area Progression in Stargardt Disease: A Comparison of En Face Optical Coherence Tomography and Fundus Autofluorescence. Translational Vision Science & Technology, 12(5), 2. https://doi.org/10.1167/tvst.12.5.2
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Moore, C. E., Yalcindag, S. E., Czeladko, H., Ravindranathan, R., Wijesekara Hanthi, Y., Levy, J. C., Sannino, V., Schindler, D., Ciccia, A., Costanzo, V., & Elia, A. E. H. (2023). RFWD3 promotes ZRANB3 recruitment to regulate the remodeling of stalled replication forks. Journal of Cell Biology, 222(5). https://doi.org/10.1083/jcb.202106022
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Sufyan, M., Daraz, U., Hyder, S., Zulfiqar, U., Iqbal, R., Eldin, S. M., Rafiq, F., Mahmood, N., Shahzad, K., Uzair, M., Fiaz, S., & Ali, I. (2023). An overview of genome engineering in plants, including its scope, technologies, progress and grand challenges. Functional & Integrative Genomics, 23(2). https://doi.org/10.1007/s10142-023-01036-w
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Shin, A. E., Giancotti, F. G., & Rustgi, A. K. (2023). Metastatic colorectal cancer: mechanisms and emerging therapeutics. Trends in Pharmacological Sciences, 44(4), 222–236. https://doi.org/10.1016/j.tips.2023.01.003
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Wang, Y.-C., Kelso, A. A., Karamafrooz, A., Chen, Y.-H., Chen, W.-K., Cheng, C.-T., Qi, Y., Gu, L., Malkas, L., Taglialatela, A., Kung, H.-J., Moldovan, G.-L., Ciccia, A., Stark, J. M., & Ann, D. K. (2023). Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination. Cell Reports, 42(4), 112296. https://doi.org/10.1016/j.celrep.2023.112296
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Gnügge, R., Reginato, G., Cejka, P., & Symington, L. S. (2023). Sequence and chromatin features guide DNA double-strand break resection initiation. Molecular Cell, 83(8), 1237-1250.e15. https://doi.org/10.1016/j.molcel.2023.02.010
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Khazaei, S., Chen, C. C. L., Andrade, A. F., Kabir, N., Azarafshar, P., Morcos, S. M., França, J. A., Lopes, M., Lund, P. J., Danieau, G., Worme, S., Adnani, L., Nzirorera, N., Chen, X., Yogarajah, G., Russo, C., Zeinieh, M., Wong, C. J., Bryant, L., … Jabado, N. (2023). Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration. Cell, 186(6), 1162-1178.e20. https://doi.org/10.1016/j.cell.2023.02.023
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Dermawan, J. K. T., Nafa, K., Mohanty, A., Xu, Y., Rijo, I., Casanova, J., Villafania, L., Benhamida, J., Kelly, C. M., Tap, W. D., Boland, P. J., Fabbri, N., Healey, J. H., Ladanyi, M., Lu, C., & Hameed, M. (2023). Distinct IDH1/2-associated Methylation Profile and Enrichment ofTP53andTERTMutations Distinguish Dedifferentiated Chondrosarcoma from Conventional Chondrosarcoma. Cancer Research Communications, 3(3), 431–443. https://doi.org/10.1158/2767-9764.crc-22-0397
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Dilbar, S., Sher, H., Binjawhar, D. N., Ali, A., & Ali, I. (2023). A Novel Based Synthesis of Silver/Silver Chloride Nanoparticles from Stachys emodi Efficiently Controls Erwinia carotovora, the Causal Agent of Blackleg and Soft Rot of Potato. Molecules, 28(6), 2500. https://doi.org/10.3390/molecules28062500
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Iannello, G., Patel, A., Sirabella, D., Diaz, A. G., Hoover, B. N., Sarmah, H., & Corneo, B. (2023). Simple, Fast, and Efficient Method for Derivation of Dermal Fibroblasts From Skin Biopsies. Current Protocols, 3(3). Portico. https://doi.org/10.1002/cpz1.714
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Parikh, A. S., Yu, V. X., Flashner, S., Okolo, O. B., Lu, C., Henick, B. S., Momen-Heravi, F., Puram, S. V., Teknos, T., Pan, Q., & Nakagawa, H. (2023). Patient-derived three-dimensional culture techniques model tumor heterogeneity in head and neck cancer. Oral Oncology, 138, 106330. https://doi.org/10.1016/j.oraloncology.2023.106330
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Galindo, S. E., Wood, A. J., Cooney, P. C., Hammond, L. A., & Grueber, W. B. (2023). Axon–axon interactions determine modality-specific wiring and subcellular synaptic specificity in a somatosensory circuit. Development, 150(5). https://doi.org/10.1242/dev.199832
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Portela-Lomba, M., Simón, D., Fernández de Sevilla, D., Moreno-Flores, M. T., & Sierra, J. (2023). Small molecules fail to induce direct reprogramming of adult rat olfactory ensheathing glia to mature neurons. Frontiers in Molecular Neuroscience, 16. https://doi.org/10.3389/fnmol.2023.1110356
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de Prisco, N., Ford, C., Elrod, N. D., Lee, W., Tang, L. C., Huang, K.-L., Lin, A., Ji, P., Jonnakuti, V. S., Boyle, L., Cabaj, M., Botta, S., Õunap, K., Reinson, K., Wojcik, M. H., Rosenfeld, J. A., Bi, W., Tveten, K., Prescott, T., … Gennarino, V. A. (2023). Alternative polyadenylation alters protein dosage by switching between intronic and 3′UTR sites. Science Advances, 9(7). https://doi.org/10.1126/sciadv.ade4814
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Murtaza, G., Ahmed, Z., Eldin, S. M., Ali, B., Bawazeer, S., Usman, M., Iqbal, R., Neupane, D., Ullah, A., Khan, A., Hassan, M. U., Ali, I., & Tariq, A. (2023). Biochar-Soil-Plant interactions: A cross talk for sustainable agriculture under changing climate. Frontiers in Environmental Science, 11. https://doi.org/10.3389/fenvs.2023.1059449
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Good, P. I., Li, L., Hurst, H. A., Serrano Herrera, I., Xu, K., Rao, M., Bateman, D. A., Al-Awqati, Q., D’Agati, V. D., Costantini, F., & Lin, F. (2023). Low nephron endowment increases susceptibility to renal stress and chronic kidney disease. JCI Insight, 8(3). https://doi.org/10.1172/jci.insight.161316
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Vasciaveo, A., Arriaga, J. M., de Almeida, F. N., Zou, M., Douglass, E. F., Picech, F., Shibata, M., Rodriguez-Calero, A., de Brot, S., Mitrofanova, A., Chua, C. W., Karan, C., Realubit, R., Pampou, S., Kim, J. Y., Afari, S. N., Mukhammadov, T., Zanella, L., Corey, E., … Abate-Shen, C. (2022). OncoLoop: A Network-Based Precision Cancer Medicine Framework. Cancer Discovery, 13(2), 386–409. https://doi.org/10.1158/2159-8290.cd-22-0342
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Wu, S., Yang, Y., Tang, R., Zhang, S., Qin, P., Lin, R., Rafel, N., Lucchetta, E. M., Ohlstein, B., & Guo, Z. (2023). Apical-basal polarity precisely determines intestinal stem cell number by regulating Prospero threshold. Cell Reports, 42(2), 112093. https://doi.org/10.1016/j.celrep.2023.112093
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Ullah, A., Ali, I., Noor, J., Zeng, F., Bawazeer, S., Eldin, S. M., Asghar, M. A., Javed, H. H., Saleem, K., Ullah, S., & Ali, H. (2023). Exogenous γ-aminobutyric acid (GABA) mitigated salinity-induced impairments in mungbean plants by regulating their nitrogen metabolism and antioxidant potential. Frontiers in Plant Science, 13. https://doi.org/10.3389/fpls.2022.1081188
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Atta, M. I., Zehra, S. S., Dai, D.-Q., Ali, H., Naveed, K., Ali, I., Sarwar, M., Ali, B., Iqbal, R., Bawazeer, S., Abdel-Hameed, U. K., & Ali, I. (2023). Amassing of heavy metals in soils, vegetables and crop plants irrigated with wastewater: Health risk assessment of heavy metals in Dera Ghazi Khan, Punjab, Pakistan. Frontiers in Plant Science, 13. https://doi.org/10.3389/fpls.2022.1080635
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DIRBAS, J., IQBAL, M. A., ISLAM, M. S., AL-ASHKAR, I., ALI, I., & EL SABAGH, A. (2023). DIALLEL MEDIATED HYBRID SCREENING BY ANALYSIS OF YIELD ATTRIBUTES, SEED YIELD AND FIBER QUALITY IN COTTON GENOTYPES. Applied Ecology and Environmental Research, 21(5), 4721–4734. https://doi.org/10.15666/aeer/2105_47214734
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Saeed, M., Ilyas, N., Bibi, F., Shabir, S., Mehmood, S., Akhtar, N., Ali, I., Bawazeer, S., Al Tawaha, A. R., & Eldin, S. M. (2023). Nanoremediation approaches for the mitigation of heavy metal contamination in vegetables: An overview. Nanotechnology Reviews, 12(1). https://doi.org/10.1515/ntrev-2023-0156
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Ressler, A. K., Sampaio, G. L. A., Dugger, S. A., Sapir, T., Krizay, D., Boland, M. J., Reiner, O., & Goldstein, D. B. (2023). Evidence of shared transcriptomic dysregulation of HNRNPU-related disorder between human organoids and embryonic mice. IScience, 26(1), 105797. https://doi.org/10.1016/j.isci.2022.105797
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Mitchell, C. A., Verovskaya, E. V., Calero-Nieto, F. J., Olson, O. C., Swann, J. W., Wang, X., Hérault, A., Dellorusso, P. V., Zhang, S. Y., Svendsen, A. F., Pietras, E. M., Bakker, S. T., Ho, T. T., Göttgens, B., & Passegué, E. (2023). Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing. Nature Cell Biology, 25(1), 30–41. https://doi.org/10.1038/s41556-022-01053-0
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Gund, R., & Christiano, A. M. (2022). Impaired autophagy promotes hair loss in the C3H/HeJ mouse model of alopecia areata. Autophagy, 19(1), 296–305. https://doi.org/10.1080/15548627.2022.2074104
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Flashner, S., Martin, C., Matsuura, N., Shimonosono, M., Tomita, Y., Morimoto, M., Okolo, O., Yu, V. X., Parikh, A. S., Klein-Szanto, A. J. P., Yan, K., Gabre, J. T., Lu, C., Momen-Heravi, F., Rustgi, A. K., & Nakagawa, H. (2022). Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids. Journal of Visualized Experiments, 190. https://doi.org/10.3791/64676
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Lee, P. J., Benz, C. C., Blood, P., Börner, K., Campisi, J., Chen, F., Daldrup-Link, H., De Jager, P., Ding, L., Duncan, F. E., Eickelberg, O., Fan, R., Finkel, T., Furman, D., Garovic, V., Gehlenborg, N., Glass, C., … Yang, M. (2022). NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health. Nature Aging, 2(12), 1090–1100. https://doi.org/10.1038/s43587-022-00326-5
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Kolesnikova, M., Oh, J. K., Wang, J., Lee, W., Zernant, J., Su, P.-Y., Kim, A. H., Jenny, L. A., Yang, T., Allikmets, R., & Tsang, S. H. (2022). A pathogenic in-frame deletion-insertion variant in BEST1 phenocopies Stargardt disease. JCI Insight, 7(23). https://doi.org/10.1172/jci.insight.162687
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Su, P.-Y., Lee, W., Zernant, J., Tsang, S. H., Nagasaki, T., Corneo, B., & Allikmets, R. (2022). Establishment of the iPSC line CUIMCi005-A from a patient with Stargardt disease for retinal organoid culture. Stem Cell Research, 65, 102973. https://doi.org/10.1016/j.scr.2022.102973
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Zhou, R. W., Xu, J., Martin, T. C., Zachem, A. L., He, J., Ozturk, S., Demircioglu, D., Bansal, A., Trotta, A. P., Giotti, B., Gryder, B., Shen, Y., Wu, X., Carcamo, S., Bosch, K., Hopkins, B., Tsankov, A., Steinhagen, R., Jones, D. R., … Parsons, R. E. (2022). A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33377-8
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de Sena-Tomás, C., Aleman, A. G., Ford, C., Varshney, A., Yao, D., Harrington, J. K., Saúde, L., Ramialison, M., & Targoff, K. L. (2022). Activation of Nkx2.5 transcriptional program is required for adult myocardial repair. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30468-4
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Erjavec, S. O., Gelfman, S., Abdelaziz, A. R., Lee, E. Y., Monga, I., Alkelai, A., Ionita-Laza, I., Petukhova, L., & Christiano, A. M. (2022). Whole exome sequencing in Alopecia Areata identifies rare variants in KRT82. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-28343-3
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Strong, R., Miller, R. A., Cheng, C. J., Nelson, J. F., Gelfond, J., Allani, S. K., Diaz, V., Dorigatti, A. O., Dorigatti, J., Fernandez, E., Galecki, A., Ginsburg, B., Hamilton, K. L., Javors, M. A., Kornfeld, K., Kaeberlein, M., Kumar, S., Lombard, D. B., Lopez‐Cruzan, M., … Harrison, D. E. (2022). Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice. Aging Cell, 21(12). Portico. https://doi.org/10.1111/acel.13724
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