Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on somatostatin- and parvalbumin-expressing cortical GABAergic neurons

Shore, A. N., Li, K., Safari, M., Qunies, A. M., Spitznagel, B. D., Weaver, C. D., Emmitte, K., Frankel, W., & Weston, M. C. (2024). Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on somatostatin- and parvalbumin-expressing cortical GABAergic neurons. ELife, 13. CLOCKSS. https://doi.org/10.7554/elife.92915
Authors:
Amy N Shore
Keyong Li
Mona Safari
Alshaima'a M Qunies
Brittany D Spitznagel
C David Weaver
Kyle Emmitte
Wayne Frankel
Matthew C Weston
Affiliated Authors:
Wayne Frankel
Columbia Affiliation:
Subjects:
Somatostatin (MeSH)
GABAergic Neurons (MeSH)
Parvalbumins (MeSH)
Gain of Function Mutation (MeSH)
Author Keywords:
kcnt1
epilepsy
cortex
action potential
interneuron
modeling
molecular biophysics
mouse
neuroscience
structural biology
elink
Publication Type:
Article
Unique ID:
10.7554/elife.92915
PMID:
39392867
DOI:
10.7554/elife.92915
Journal:
eLife
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Web of Science Record

Record Created: