Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration

Khazaei, S., Chen, C. C. L., Andrade, A. F., Kabir, N., Azarafshar, P., Morcos, S. M., França, J. A., Lopes, M., Lund, P. J., Danieau, G., Worme, S., Adnani, L., Nzirorera, N., Chen, X., Yogarajah, G., Russo, C., Zeinieh, M., Wong, C. J., Bryant, L., … Jabado, N. (2023). Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration. Cell, 186(6), 1162-1178.e20. https://doi.org/10.1016/j.cell.2023.02.023
Authors:
Sima Khazaei
Carol C L Chen
Augusto Faria Andrade
Nisha Kabir
Pariya Azarafshar
Shahir M Morcos
Josiane Alves França
Mariana Lopes
Peder J Lund
Geoffroy Danieau
Samantha Worme
Lata Adnani
Nadine Nzirorera
Xiao Chen
Gayathri Yogarajah
Caterina Russo
Michele Zeinieh
Cassandra J Wong
Laura Bryant
Steven Hébert
Bethany Tong
Tianna S Sihota
Damien Faury
Evan Puligandla
Wajih Jawhar
Veronica Sandy
Mitra Cowan
Emily M Nakada
Loydie A Jerome-Majewska
Benjamin Ellezam
Carolina Cavalieri Gomes
Jonas Denecke
Davor Lessel
Marie T McDonald
Carolyn E Pizoli
Kathryn Taylor
Benjamin T Cocanougher
Elizabeth J Bhoj
Anne-Claude Gingras
Benjamin A Garcia
Chao Lu
Eric I Campos
Claudia L Kleinman
Livia Garzia
Nada Jabado
Affiliated Authors:
Xiao Chen
Chao Lu
Columbia Affiliation:
Subjects:
DNA Methyltransferase 3A (MeSH)
Histones (MeSH)
Author Keywords:
ch methylation
complement
dna methylation
dnmt3a
h3.3 g34r/v/w
h3k36me2
neurodegeneration
neuroinflammation
oncohistones
synaptic pruning
elink
Publication Type:
Article
Unique ID:
10.1016/j.cell.2023.02.023
PMID:
36931244
DOI:
10.1016/j.cell.2023.02.023
Journal:
Cell
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record

Record Created: