Nature Communications
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Lu, C., Kang, T., Zhang, J., Yang, K., Liu, Y., Song, K., Lin, Q., Dixit, D., Gimple, R. C., Zhang, Q., Shi, Z., Fan, X., Wu, Q., Li, D., Shan, D., Gao, J., Gu, D., You, H., Li, Y., … Wang, X. (2025). Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58366-5
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Zhao, J., Gu, T., Gao, C., Miao, G., Palma-Gudiel, H., Yu, L., Yang, J., Wang, Y., Li, Y., Lim, J., Li, R., Yao, B., Wu, H., Schneider, J. A., Seyfried, N., Grodstein, F., De Jager, P. L., Jin, P., & Bennett, D. A. (2025). Brain 5-hydroxymethylcytosine alterations are associated with Alzheimer’s disease neuropathology. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58159-w
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Nixon-Abell, J., Ruggeri, F. S., Qamar, S., Herling, T. W., Czekalska, M. A., Shen, Y., Wang, G., King, C., Fernandopulle, M. S., Sneideris, T., Watson, J. L., Pillai, V. V. S., Meadows, W., Henderson, J. W., Chambers, J. E., Wagstaff, J. L., Williams, S. H., Coyle, H., Šneiderienė, G., … St George-Hyslop, P. (2025). ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58142-5
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Jiang, W., Jaehnig, E. J., Liao, Y., Shi, Z., Yaron-Barir, T. M., Johnson, J. L., Cantley, L. C., & Zhang, B. (2025). Deciphering the dark cancer phosphoproteome using machine-learned co-regulation of phosphosites. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57993-2
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Singh, D., Robin, T., Urbakh, M., & Reuveni, S. (2025). High-order Michaelis-Menten equations allow inference of hidden kinetic parameters in enzyme catalysis. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57327-2
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Mangione, R. M., Pierce, S., Zheng, M., Martin, R. M., Goncalves, C., Kumar, A., Scaglione, S., de Sousa Morgado, C., Penzo, A., Lancrey, A., Reid, R. J. D., Lautier, O., Gaillard, P.-H., Stirling, P. C., de Almeida, S. F., Rothstein, R., & Palancade, B. (2025). DNA lesions can frequently precede DNA:RNA hybrid accumulation. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57588-x
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Kim, J., Williams, A., Noh, H., Jasper, E. A., Jones, S. H., Jaworski, J. A., Shuey, M. M., Ruiz-Narváez, E. A., Wise, L. A., Palmer, J. R., Connolly, J., Keaton, J. M., Denny, J. C., Khan, A., Abbass, M. A., Rasmussen-Torvik, L. J., Kottyan, L. C., Madhivanan, P., Krupp, K., … Hellwege, J. N. (2025). Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57483-5
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Vann, K. R., Sharma, R., Hsu, C.-C., Devoucoux, M., Tencer, A. H., Zeng, L., Lin, K., Zhu, L., Li, Q., Lachance, C., Ospina, R. R., Tong, Q., Cheung, K. L., Yang, S., Biswas, S., Xuan, H., Gatchalian, J., Alamillo, L., Wang, J., … Kutateladze, T. G. (2025). Structure-function relationship of ASH1L and histone H3K36 and H3K4 methylation. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57556-5
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Loffredo, L. F., Kustagi, A., Ringham, O. R., Li, F., de los Santos-Alexis, K., Saqi, A., & Arpaia, N. (2025). Heparan sulfate regulates amphiregulin programming of tissue reparative lung mesenchymal cells during influenza A virus infection in mice. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57362-z
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Rubinelli, L., Manzo, O. L., Sungho, J., Del Gaudio, I., Bareja, R., Marino, A., Palikhe, S., Di Mauro, V., Bucci, M., Falcone, D. J., Elemento, O., Ersoy, B., Diano, S., Sasset, L., & Di Lorenzo, A. (2025). Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56869-9
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Arnold, M., Buyukozkan, M., Doraiswamy, P. M., Nho, K., Wu, T., Gudnason, V., Launer, L. J., Wang-Sattler, R., Adamski, J., De Jager, P. L., Ertekin-Taner, N., Bennett, D. A., Saykin, A. J., Peters, A., Suhre, K., Kaddurah-Daouk, R., Kastenmüller, G., & Krumsiek, J. (2025). Individual bioenergetic capacity as a potential source of resilience to Alzheimer’s disease. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57032-0
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Yuan, F., Yang, J., Ma, F., Hu, Z., Malik, V., Zang, R., Li, D., Shi, X., Huang, X., Zhou, H., & Wang, J. (2025). Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57165-2
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Mitchell, J., Camacho, N., Shea, P., Stopsack, K. H., Joseph, V., Burren, O. S., Dhindsa, R. S., Nag, A., Berchuck, J. E., O’Neill, A., Abbasi, A., Zoghbi, A. W., Alegre-Díaz, J., Kuri-Morales, P., Berumen, J., Tapia-Conyer, R., Emberson, J., Torres, J. M., Collins, R., … Fabre, M. A. (2025). Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56944-1
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Di Matteo, F., Bonrath, R., Pravata, V., Schmidt, H., Ayo Martin, A. C., Di Giaimo, R., Menegaz, D., Riesenberg, S., de Vrij, F. M. S., Maccarrone, G., Holzapfel, M., Straub, T., Kushner, S. A., Robertson, S. P., Eder, M., & Cappello, S. (2025). Neuronal hyperactivity in neurons derived from individuals with gray matter heterotopia. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56998-1
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Zhang, P., Du, Q., Wang, Y., Wei, L., & Wang, X. (2025). Systematic representation and optimization enable the inverse design of cross-species regulatory sequences in bacteria. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57031-1
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Dharmadhikari, A. V., Abad, M. A., Khan, S., Maroofian, R., Sands, T. T., Ullah, F., Samejima, I., Shen, Y., Wear, M. A., Moore, K. E., Kondakova, E., Mitina, N., Schaub, T., Lee, G. K., Umandap, C. H., Berger, S. M., Iglesias, A. D., Popp, B., Abou Jamra, R., … Liao, J. (2025). RNA methyltransferase SPOUT1/CENP-32 links mitotic spindle organization with the neurodevelopmental disorder SpADMiSS. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56876-w
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Vagelos College of Physicians and Surgeons; Department of Neurology; Division of Child Neurology; Department of Pediatrics; Division of Critical Care and Hospital Medicine; Department of Medicine; Seymour, Paul and Gloria Milstein Division of Cardiology; Division of Nephrology; Department of Pathology and Cell Biology; Division of Clinical Genetics; Institute for Genomic Medicine
Craig-Schapiro, R., Li, G., Chen, K., Gomez-Salinero, J. M., Nachman, R., Kopacz, A., Schreiner, R., Chen, X., Zhou, Q., Rafii, S., & Redmond, D. (2025). Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55415-3
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Mondal, J., Zhang, J., Qing, F., Li, S., Kumar, D., Huse, J. T., & Giancotti, F. G. (2025). Brd7 loss reawakens dormant metastasis initiating cells in lung by forging an immunosuppressive niche. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56347-2
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Doron-Mandel, E., Bokor, B. J., Ma, Y., Street, L. A., Tang, L. C., Abdou, A. A., Shah, N. H., Rosenberger, G., & Jovanovic, M. (2025). SEC-MX: an approach to systematically study the interplay between protein assembly states and phosphorylation. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56303-0
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Guo, M. H., Lee, W.-P., Vardarajan, B., Schellenberg, G. D., & Phillips-Cremins, J. E. (2025). Polygenic burden of short tandem repeat expansions promotes risk for Alzheimer’s disease. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56400-0
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Zhang, D., Zhang, B., Wu, Q., Zhou, T., Tong, J., Lu, Y., Chen, J., Wang, H., Chisolm, D. J., Jhaveri, R., Kenney, R. C., Rothman, R. L., Rao, S., Williams, D. A., Hornig, M., Wang, L., Morris, J. S., Forrest, C. B., & Chen, Y. (2025). Racial/ethnic differences in post-acute sequelae of SARS-CoV-2 in children and adolescents in the United States. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55273-z
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Wang, Z., Liu, Z., Fang, Y., Zhang, H. H., Sun, X., Hao, N., Que, J., & Ding, H. (2025). Training data diversity enhances the basecalling of novel RNA modification-induced nanopore sequencing readouts. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-55974-z
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Wisniewski, D. J., Ma, L., Rauhala, O. J., Cea, C., Zhao, Z., Ranschaert, A., Gelinas, J. N., & Khodagholy, D. (2025). Spatial control of doping in conducting polymers enables complementary, conformable, implantable internal ion-gated organic electrochemical transistors. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55284-w
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Park, J., Karnati, H., Rustgi, S. D., Hur, C., Kong, X.-F., & Kastrinos, F. (2025). Impact of population screening for Lynch syndrome insights from the All of Us data. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-52562-5
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Larrea, D., Tamucci, K. A., Kabra, K., Velasco, K. R., Yun, T. D., Pera, M., Montesinos, J., Agrawal, R. R., Paradas, C., Smerdon, J. W., Lowry, E. R., Stepanova, A., Yoval-Sanchez, B., Galkin, A., Wichterle, H., & Area-Gomez, E. (2025). Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS). Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-51578-1
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Duan, S., Nodelman, I. M., Zhou, H., Tsukiyama, T., Bowman, G. D., & Zhang, Z. (2025). H3K56 acetylation regulates chromatin maturation following DNA replication. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55144-7
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Liu, H., Zask, A., Forouhar, F., Iketani, S., Williams, A., Vaz, D. R., Habashi, D., Choi, K., Resnick, S. J., Hong, S. J., Lovett, D. H., Bai, T., Chavez, A., Ho, D. D., & Stockwell, B. R. (2025). Development of small molecule non-covalent coronavirus 3CL protease inhibitors from DNA-encoded chemical library screening. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55421-5
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Kizhatil, K., Clark, G. M., Sunderland, D. K., Bhandari, A., Horbal, L. J., Balasubramanian, R., & John, S. W. M. (2025). FYN regulates aqueous humor outflow and IOP through the phosphorylation of VE-CADHERIN. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55232-8
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Shi, X., Li, Y., Zhou, H., Hou, X., Yang, J., Malik, V., Faiola, F., Ding, J., Bao, X., Modic, M., Zhang, W., Chen, L., Mahmood, S. R., Apostolou, E., Yang, F.-C., Xu, M., Xie, W., Huang, X., Chen, Y., & Wang, J. (2024). DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-55054-8
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Stein, M. N., Dumbrava, E. E., Teply, B. A., Gergis, U. S., Guiterrez, M. E., Reshef, R., Subudhi, S. K., Jacquemont, C. F., Senesac, J. H., Bayle, J. H., Scripture, C. D., Chatwal, M. S., Bilen, M. A., Stadler, W. M., & Becerra, C. R. (2024). PSCA-targeted BPX-601 CAR T cells with pharmacological activation by rimiducid in metastatic pancreatic and prostate cancer: a phase 1 dose escalation trial. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-53220-6
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Pedroni, A., Yilmaz, E., Del Vecchio, L., Bhattarai, P., Vidal, I. T., Dai, Y.-W. E., Koutsogiannis, K., Kizil, C., & Ampatzis, K. (2024). Decoding the molecular, cellular, and functional heterogeneity of zebrafish intracardiac nervous system. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-54830-w
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Faust, H. J., Cheng, T.-Y., Korsunsky, I., Watts, G. F. M., Gal-Oz, S. T., Trim, W. V., Kongthong, S., Jonsson, A. H., Simmons, D. P., Zhang, F., Padera, R., Chubinskaya, S., Albrecht, J., Anolik, J. H., Apruzzese, W., Barnas, J. L., Bathon, J. M., Ben-Artzi, A., … Brenner, M. B. (2024). Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52586-x
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Hofmann, A., Häsler, L. M., Lambert, M., Kaeser, S. A., Gräber-Sultan, S., Obermüller, U., Kuder-Buletta, E., la Fougere, C., Laske, C., Vöglein, J., Levin, J., Fox, N. C., Ryan, N. S., Zetterberg, H., Llibre-Guerra, J. J., Perrin, R. J., Ibanez, L., Schofield, P. R., Brooks, W. S., … Xu, J. (2024). Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s disease. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52937-8
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Trastulla, L., Dolgalev, G., Moser, S., Jiménez-Barrón, L. T., Andlauer, T. F. M., von Scheidt, M., Ruderfer, D. M., Ripke, S., McQuillin, A., Stahl, E. A., Domenici, E., Adolfsson, R., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., … Ziller, M. J. (2024). Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-49338-2
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Sun, H., Mehta, S., Khaitova, M., Cheng, B., Hao, X., Spann, M., & Scheinost, D. (2024). Brain age prediction and deviations from normative trajectories in the neonatal connectome. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-54657-5
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Gangwar, S. P., Yelshanskaya, M. V., Aktolun, M., Yen, L. Y., Newton, T. P., Strømgaard, K., Kurnikova, M. G., & Sobolevsky, A. I. (2024). Trapping of spermine, Kukoamine A, and polyamine toxin blockers in GluK2 kainate receptor channels. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-54538-x
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Powers, A. S., Khan, A., Paggi, J. M., Latorraca, N. R., Souza, S., Di Salvo, J., Lu, J., Soisson, S. M., Johnston, J. M., Weinglass, A. B., & Dror, R. O. (2024). A non-canonical mechanism of GPCR activation. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-54103-6
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Vockert, N., Machts, J., Kleineidam, L., Nemali, A., Incesoy, E. I., Bernal, J., Schütze, H., Yakupov, R., Peters, O., Gref, D., Schneider, L. S., Preis, L., Priller, J., Spruth, E. J., Altenstein, S., Schneider, A., Fliessbach, K., Wiltfang, J., … Rostamzadeh, A. (2024). Cognitive reserve against Alzheimer’s pathology is linked to brain activity during memory formation. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-53360-9
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Gao, V. R., Yang, R., Das, A., Luo, R., Luo, H., McNally, D. R., Karagiannidis, I., Rivas, M. A., Wang, Z.-M., Barisic, D., Karbalayghareh, A., Wong, W., Zhan, Y. A., Chin, C. R., Noble, W. S., Bilmes, J. A., Apostolou, E., Kharas, M. G., Béguelin, W., … Leslie, C. S. (2024). ChromaFold predicts the 3D contact map from single-cell chromatin accessibility. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-53628-0
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Shafighi, S., Geras, A., Jurzysta, B., Sahaf Naeini, A., Filipiuk, I., Ra̧czkowska, A., Toosi, H., Koperski, Ł., Thrane, K., Engblom, C., Mold, J. E., Chen, X., Hartman, J., Nowis, D., Carbone, A., Lagergren, J., & Szczurek, E. (2024). Integrative spatial and genomic analysis of tumor heterogeneity with Tumoroscope. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-53374-3
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Matsui, M., Lynch, L. E., Distefano, I., Galante, A., Gade, A. R., Wang, H.-G., Gómez-Banoy, N., Towers, P., Sinden, D. S., Wei, E. Q., Barnett, A. S., Johnson, K., Lima, R., Rubio-Navarro, A., Li, A. K., Marx, S. O., McGraw, T. E., Thornton, P. S., Timothy, K. W., … Pitt, G. S. (2024). Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52885-3
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Kefeli, J., Berkowitz, J., Acitores Cortina, J. M., Tsang, K. K., & Tatonetti, N. P. (2024). Generalizable and automated classification of TNM stage from pathology reports with external validation. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-53190-9
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Marcink, T. C., Zipursky, G., Sobolik, E. B., Golub, K., Herman, E., Stearns, K., Greninger, A. L., Porotto, M., & Moscona, A. (2024). How a paramyxovirus fusion/entry complex adapts to escape a neutralizing antibody. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-53082-y
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Ndembi, N., Mekonen, T. T., Folayan, M. O., Dereje, N., Kruger, A., Fokam, J., Temfack, E., Raji, T., Nachega, J., Boum, Y., Crowell, T. A., Ngongo, A. N., Mboup, S., Ntoumi, F., Loots, G., Makanga, M., Sow, S., Karim, S. A., & Nkengasong, J. (2024). Strengthening and expanding capacities in clinical trials: advancing pandemic prevention, preparedness and response in Africa. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-53126-3
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Lin, X., Provasi, D., Niswender, C. M., Asher, W. B., & Javitch, J. A. (2024). Elucidating the molecular logic of a metabotropic glutamate receptor heterodimer. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52822-4
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Wu, Y., Foollee, A., Chan, A. Y., Hille, S., Hauke, J., Challis, M. P., Johnson, J. L., Yaron, T. M., Mynard, V., Aung, O. H., Cleofe, M. A. S., Huang, C., Lim Kam Sian, T. C. C., Rahbari, M., Gallage, S., Heikenwalder, M., Cantley, L. C., Schittenhelm, R. B., Formosa, L. E., … Rose, A. J. (2024). Phosphoproteomics-directed manipulation reveals SEC22B as a hepatocellular signaling node governing metabolic actions of glucagon. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52703-w
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Collins, C. A., Waller, C., Batourina, E., Kumar, L., Mendelsohn, C. L., & Gilbert, N. M. (2024). Nur77 protects the bladder urothelium from intracellular bacterial infection. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52454-8
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Nho, K., Risacher, S. L., Apostolova, L. G., Bice, P. J., Brosch, J. R., Deardorff, R., Faber, K., Farlow, M. R., Foroud, T., Gao, S., Rosewood, T., Kim, J. P., Nudelman, K., Yu, M., Aisen, P., Sperling, R., Hooli, B., Shcherbinin, S., Svaldi, D., … Saykin, A. J. (2024). CYP1B1-RMDN2 Alzheimer’s disease endophenotype locus identified for cerebral tau PET. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52298-2
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Havel, V., Kruegel, A. C., Bechand, B., McIntosh, S., Stallings, L., Hodges, A., Wulf, M. G., Nelson, M., Hunkele, A., Ansonoff, M., Pintar, J. E., Hwu, C., Ople, R. S., Abi-Gerges, N., Zaidi, S. A., Katritch, V., Yang, M., Javitch, J. A., Majumdar, S., … Sames, D. (2024). Oxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-51856-y
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Link, K. E., Schnurman, Z., Liu, C., Kwon, Y. J., Jiang, L. Y., Nasir-Moin, M., Neifert, S., Alzate, J. D., Bernstein, K., Qu, T., Chen, V., Yang, E., Golfinos, J. G., Orringer, D., Kondziolka, D., & Oermann, E. K. (2024). Longitudinal deep neural networks for assessing metastatic brain cancer on a large open benchmark. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52414-2
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