Zhou, R. W., Xu, J., Martin, T. C., Zachem, A. L., He, J., Ozturk, S., Demircioglu, D., Bansal, A., Trotta, A. P., Giotti, B., Gryder, B., Shen, Y., Wu, X., Carcamo, S., Bosch, K., Hopkins, B., Tsankov, A., Steinhagen, R., Jones, D. R., … Parsons, R. E. (2022). A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33377-8

Kurniansyah, N., Goodman, M. O., Kelly, T. N., Elfassy, T., Wiggins, K. L., Bis, J. C., Guo, X., Palmas, W., Taylor, K. D., Lin, H. J., Haessler, J., Gao, Y., Shimbo, D., Smith, J. A., Yu, B., Feofanova, E. V., Smit, R. A. J., Wang, Z., Hwang, S.-J., … Sofer, T. (2022). A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31080-2

Winans, S., Yu, H. J., de los Santos, K., Wang, G. Z., KewalRamani, V. N., & Goff, S. P. (2022). A point mutation in HIV-1 integrase redirects proviral integration into centromeric repeats. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29097-8

de Sena-Tomás, C., Aleman, A. G., Ford, C., Varshney, A., Yao, D., Harrington, J. K., Saúde, L., Ramialison, M., & Targoff, K. L. (2022). Activation of Nkx2.5 transcriptional program is required for adult myocardial repair. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30468-4

Park, J., Li, J., Mayer, J. P., Ball, K. A., Wu, J., Hall, C., Accili, D., Stowell, M. H. B., Bai, X., & Choi, E. (2022). Activation of the insulin receptor by an insulin mimetic peptide. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33274-0

Rabadan, M. A., De La Cruz, E. D., Rao, S. B., Chen, Y., Gong, C., Crabtree, G., Xu, B., Markx, S., Gogos, J. A., Yuste, R., & Tomer, R. (2022). An in vitro model of neuronal ensembles. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31073-1

Primakov, S. P., Ibrahim, A., van Timmeren, J. E., Wu, G., Keek, S. A., Beuque, M., Granzier, R. W. Y., Lavrova, E., Scrivener, M., Sanduleanu, S., Kayan, E., Halilaj, I., Lenaers, A., Wu, J., Monshouwer, R., Geets, X., Gietema, H. A., Hendriks, L. E. L., Morin, O., … Lambin, P. (2022). Automated detection and segmentation of non-small cell lung cancer computed tomography images. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30841-3

Lee, A., Kondapalli, C., Virga, D. M., Lewis, T. L., Koo, S. Y., Ashok, A., Mairet-Coello, G., Herzig, S., Foretz, M., Viollet, B., Shaw, R., Sproul, A., & Polleux, F. (2022). Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32130-5

Filippone, M. G., Gaglio, D., Bonfanti, R., Tucci, F. A., Ceccacci, E., Pennisi, R., Bonanomi, M., Jodice, G., Tillhon, M., Montani, F., Bertalot, G., Freddi, S., Vecchi, M., Taglialatela, A., Romanenghi, M., Romeo, F., Bianco, N., Munzone, E., Sanguedolce, F., … Pece, S. (2022). CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30375-8

Meister, J., Bone, D. B. J., Knudsen, J. R., Barella, L. F., Velenosi, T. J., Akhmedov, D., Lee, R. J., Cohen, A. H., Gavrilova, O., Cui, Y., Karsenty, G., Chen, M., Weinstein, L. S., Kleinert, M., Berdeaux, R., Jensen, T. E., Richter, E. A., & Wess, J. (2022). Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells. Nature Communications, 13(1). https://doi.org/10.1038/s41467-021-27540-w

Uddin, M. d M., Nguyen, N. Q. H., Yu, B., Brody, J. A., Pampana, A., Nakao, T., Fornage, M., Bressler, J., Sotoodehnia, N., Weinstock, J. S., Honigberg, M. C., Nachun, D., Bhattacharya, R., Griffin, G. K., Chander, V., Gibbs, R. A., Rotter, J. I., Liu, C., Baccarelli, A. A., … Conneely, K. N. (2022). Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33093-3

Chadwick, F. J., Clark, J., Chowdhury, S., Chowdhury, T., Pascall, D. J., Haddou, Y., Andrecka, J., Kundegorski, M., Wilkie, C., Brum, E., Shirin, T., Alamgir, A. S. M., Rahman, M., Alam, A. N., Khan, F., Swallow, B., Mair, F. S., Illian, J., Trotter, C. L., … Sania, A. (2022). Combining rapid antigen testing and syndromic surveillance improves community-based COVID-19 detection in a low-income country. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30640-w

Pei, S., Kandula, S., Cascante Vega, J., Yang, W., Foerster, S., Thompson, C., Baumgartner, J., Ahuja, S. D., Blaney, K., Varma, J. K., Long, T., & Shaman, J. (2022). Contact tracing reveals community transmission of COVID-19 in New York City. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34130-x

Teng, S., Zhen, F., Wang, L., Schalchli, J. C., Simko, J., Chen, X., Jin, H., Makinson, C. D., & Peng, Y. (2022). Control of non-REM sleep by ventrolateral medulla glutamatergic neurons projecting to the preoptic area. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32461-3

Tran, V.-T., Porcher, R., Pane, I., & Ravaud, P. (2022). Course of post COVID-19 disease symptoms over time in the ComPaRe long COVID prospective e-cohort. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29513-z

Xie, K., Fuchs, H., Scifo, E., Liu, D., Aziz, A., Aguilar-Pimentel, J. A., Amarie, O. V., Becker, L., da Silva-Buttkus, P., Calzada-Wack, J., Cho, Y.-L., Deng, Y., Edwards, A. C., Garrett, L., Georgopoulou, C., Gerlini, R., Hölter, S. M., Klein-Rodewald, T., Kramer, M., … Ehninger, D. (2022). Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34515-y

Sasako, T., Umehara, T., Soeda, K., Kaneko, K., Suzuki, M., Kobayashi, N., Okazaki, Y., Tamura-Nakano, M., Chiba, T., Accili, D., Kahn, C. R., Noda, T., Asahara, H., Yamauchi, T., Kadowaki, T., & Ueki, K. (2022). Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33008-2

Liu, H., Iketani, S., Zask, A., Khanizeman, N., Bednarova, E., Forouhar, F., Fowler, B., Hong, S. J., Mohri, H., Nair, M. S., Huang, Y., Tay, N. E. S., Lee, S., Karan, C., Resnick, S. J., Quinn, C., Li, W., Shion, H., Xia, X., … Stockwell, B. R. (2022). Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29413-2

Duong, M. T., Das, S. R., Lyu, X., Xie, L., Richardson, H., Xie, S. X., Yushkevich, P. A., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J. C., … Nasrallah, I. M. (2022). Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-28941-1

Wielscher, M., Mandaviya, P. R., Kuehnel, B., Joehanes, R., Mustafa, R., Robinson, O., Zhang, Y., Bodinier, B., Walton, E., Mishra, P. P., Schlosser, P., Wilson, R., Tsai, P.-C., Palaniswamy, S., Marioni, R. E., Fiorito, G., Cugliari, G., Karhunen, V., Ghanbari, M., … Järvelin, M.-R. (2022). DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29792-6

Kalmbach, A., Winiger, V., Jeong, N., Asok, A., Gallistel, C. R., Balsam, P. D., & Simpson, E. H. (2022). Dopamine encodes real-time reward availability and transitions between reward availability states on different timescales. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31377-2

Wang, X., Vincent, E., Siddiqui, S., Turnbull, K., Lu, H., Blair, R., Wu, X., Watkins, M., Ziani, W., Shao, J., Doyle-Meyers, L. A., Russell-Lodrigue, K. E., Bohm, R. P., Veazey, R. S., & Xu, H. (2022). Early treatment regimens achieve sustained virologic remission in infant macaques infected with SIV at birth. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32554-z

Boyé, K., Geraldo, L. H., Furtado, J., Pibouin-Fragner, L., Poulet, M., Kim, D., Nelson, B., Xu, Y., Jacob, L., Maissa, N., Agalliu, D., Claesson-Welsh, L., Ackerman, S. L., & Eichmann, A. (2022). Endothelial Unc5B controls blood-brain barrier integrity. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-28785-9

Liu, L., Khan, A., Sanchez-Rodriguez, E., Zanoni, F., Li, Y., Steers, N., Balderes, O., Zhang, J., Krithivasan, P., LeDesma, R. A., Fischman, C., Hebbring, S. J., Harley, J. B., Moncrieffe, H., Kottyan, L. C., Namjou-Khales, B., Walunas, T. L., Knevel, R., Raychaudhuri, S., … Kiryluk, K. (2022). Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34456-6

Levin, M. G., Tsao, N. L., Singhal, P., Liu, C., Vy, H. M. T., Paranjpe, I., Backman, J. D., Bellomo, T. R., Bone, W. P., Biddinger, K. J., Hui, Q., Dikilitas, O., Satterfield, B. A., Yang, Y., Morley, M. P., Bradford, Y., Burke, M., Reza, N., Charest, B., … Damrauer, S. M. (2022). Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34216-6

Sing, C. N., Garcia, E. J., Lipkin, T. G., Huckaba, T. M., Tsang, C. A., Coughlin, A. C., Yang, E. J., Boldogh, I. R., Higuchi-Sanabria, R., & Pon, L. A. (2022). Identification of a modulator of the actin cytoskeleton, mitochondria, nutrient metabolism and lifespan in yeast. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30045-9

Lin, C., Yang, Q., Guo, D., Xie, J., Yang, Y.-S., Chaugule, S., DeSouza, N., Oh, W.-T., Li, R., Chen, Z., John, A. A., Qiu, Q., Zhu, L. J., Greenblatt, M. B., Ghosh, S., Li, S., Gao, G., Haynes, C., Emerson, C. P., & Shim, J.-H. (2022). Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34694-8

Baran, N., Lodi, A., Dhungana, Y., Herbrich, S., Collins, M., Sweeney, S., Pandey, R., Skwarska, A., Patel, S., Tremblay, M., Kuruvilla, V. M., Cavazos, A., Kaplan, M., Warmoes, M. O., Veiga, D. T., Furudate, K., Rojas-Sutterin, S., Haman, A., Gareau, Y., … Konopleva, M. (2022). Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30396-3

Fabian, P., Tseng, K.-C., Thiruppathy, M., Arata, C., Chen, H.-J., Smeeton, J., Nelson, N., & Crump, J. G. (2022). Lifelong single-cell profiling of cranial neural crest diversification in zebrafish. Nature Communications, 13(1). https://doi.org/10.1038/s41467-021-27594-w

Marie, L., & Symington, L. S. (2022). Mechanism for inverted-repeat recombination induced by a replication fork barrier. Nature Communications, 13(1). https://doi.org/10.1038/s41467-021-27443-w

Huang, H., Pan, W., Wang, Y., Kim, H. S., Shao, D., Huang, B., Ho, T.-C., Lao, Y.-H., Quek, C. H., Shi, J., Chen, Q., Shi, B., Zhang, S., Zhao, L., & Leong, K. W. (2022). Nanoparticulate cell-free DNA scavenger for treating inflammatory bone loss in periodontitis. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33492-6

Reynard, O., Gonzalez, C., Dumont, C., Iampietro, M., Ferren, M., Le Guellec, S., Laurie, L., Mathieu, C., Carpentier, G., Roseau, G., Bovier, F. T., Zhu, Y., Le Pennec, D., Montharu, J., Addetia, A., Greninger, A. L., Alabi, C. A., Brisebard, E., Moscona, A., … Horvat, B. (2022). Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33832-6

Khan, K., Karim, F., Ganga, Y., Bernstein, M., Jule, Z., Reedoy, K., Cele, S., Lustig, G., Amoako, D., Wolter, N., Samsunder, N., Sivro, A., San, J. E., Giandhari, J., Tegally, H., Pillay, S., Naidoo, Y., Mazibuko, M., Miya, Y., … Sigal, A. (2022). Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32396-9

Lin, J., Cheng, Z., Yang, G., & Cui, M. (2022). Optical gearbox enabled versatile multiscale high-throughput multiphoton functional imaging. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34472-6

Paik, P. K., Luo, J., Ai, N., Kim, R., Ahn, L., Biswas, A., Coker, C., Ma, W., Wong, P., Buonocore, D. J., Lai, W. V., Chaft, J. E., Acharyya, S., Massagué, J., & Kris, M. G. (2022). Phase I trial of the TNF-α inhibitor certolizumab plus chemotherapy in stage IV lung adenocarcinomas. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33719-6

Cordo’, V., Meijer, M. T., Hagelaar, R., de Goeij-de Haas, R. R., Poort, V. M., Henneman, A. A., Piersma, S. R., Pham, T. V., Oshima, K., Ferrando, A. A., Zaman, G. J. R., Jimenez, C. R., & Meijerink, J. P. P. (2022). Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-28682-1

Jiang, Y., Alam, J. J., Gomperts, S. N., Maruff, P., Lemstra, A. W., Germann, U. A., Stavrides, P. H., Darji, S., Malampati, S., Peddy, J., Bleiwas, C., Pawlik, M., Pensalfini, A., Yang, D.-S., Subbanna, S., Basavarajappa, B. S., Smiley, J. F., Gardner, A., Blackburn, K., … Nixon, R. A. (2022). Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32944-3

de Vries, L. E., Jansen, P. A. M., Barcelo, C., Munro, J., Verhoef, J. M. J., Pasaje, C. F. A., Rubiano, K., Striepen, J., Abla, N., Berning, L., Bolscher, J. M., Demarta-Gatsi, C., Henderson, R. W. M., Huijs, T., Koolen, K. M. J., Tumwebaze, P. K., Yeo, T., Aguiar, A. C. C., Angulo-Barturen, I., … Dechering, K. J. (2022). Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29688-5

Lee, S. B., Garofano, L., Ko, A., D’Angelo, F., Frangaj, B., Sommer, D., Gan, Q., Kim, K., Cardozo, T., Iavarone, A., & Lasorella, A. (2022). Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29502-2

Asadzadeh, J., Ruchti, E., Jiao, W., Limoni, G., MacLachlan, C., Small, S. A., Knott, G., Santa-Maria, I., & McCabe, B. D. (2022). Retromer deficiency in Tauopathy models enhances the truncation and toxicity of Tau. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32683-5

Kabir, M. F., Karami, A. L., Cruz-Acuña, R., Klochkova, A., Saxena, R., Mu, A., Murray, M. G., Cruz, J., Fuller, A. D., Clevenger, M. H., Chitrala, K. N., Tan, Y., Keith, K., Madzo, J., Huang, H., Jelinek, J., Karakasheva, T., Hamilton, K. E., Muir, A. B., … Whelan, K. A. (2022). Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29747-x

El Chehadeh, S., Han, K. A., Kim, D., Jang, G., Bakhtiari, S., Lim, D., Kim, H. Y., Kim, J., Kim, H., Wynn, J., Chung, W. K., Vitiello, G., Cutcutache, I., Page, M., Gecz, J., Harper, K., Han, A., Kim, H. M., Wessels, M., … Um, J. W. (2022). SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31566-z

Xu, X., Duan, S., Hua, X., Li, Z., He, R., & Zhang, Z. (2022). Stable inheritance of H3.3-containing nucleosomes during mitotic cell divisions. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30298-4

Wang, T.-H., Tseng, W.-C., Leu, Y.-L., Chen, C.-Y., Lee, W.-C., Chi, Y.-C., Cheng, S.-F., Lai, C.-Y., Kuo, C.-H., Yang, S.-L., Yang, S.-H., Shen, J.-J., Feng, C.-H., Wu, C.-C., Hwang, T.-L., Wang, C.-J., Wang, S.-H., & Chen, C.-C. (2022). The flavonoid corylin exhibits lifespan extension properties in mouse. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-28908-2

Islam, M. N., Gusarova, G. A., Das, S. R., Li, L., Monma, E., Anjaneyulu, M., Mthunzi, L., Quadri, S. K., Owusu-Ansah, E., Bhattacharya, S., & Bhattacharya, J. (2022). The mitochondrial calcium uniporter of pulmonary type 2 cells determines severity of acute lung injury. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33543-y

Patel, T., Hammelman, J., Aziz, S., Jang, S., Closser, M., Michaels, T. L., Blum, J. A., Gifford, D. K., & Wichterle, H. (2022). Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33022-4

Mucha, B., Qie, S., Bajpai, S., Tarallo, V., Diehl, J. N., Tedeschi, F., Zhou, G., Gao, Z., Flashner, S., Klein-Szanto, A. J., Hibshoosh, H., Masataka, S., Chajewski, O. S., Majsterek, I., Pytel, D., Hatzoglou, M., Der, C. J., Nakagawa, H., Bass, A. J., … Diehl, J. A. (2022). Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34402-6

Erjavec, S. O., Gelfman, S., Abdelaziz, A. R., Lee, E. Y., Monga, I., Alkelai, A., Ionita-Laza, I., Petukhova, L., & Christiano, A. M. (2022). Whole exome sequencing in Alopecia Areata identifies rare variants in KRT82. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-28343-3

He, Z., Liu, L., Belloy, M. E., Le Guen, Y., Sossin, A., Liu, X., Qi, X., Ma, S., Gyawali, P. K., Wyss-Coray, T., Tang, H., Sabatti, C., Candès, E., Greicius, M. D., & Ionita-Laza, I. (2022). GhostKnockoff inference empowers identification of putative causal variants in genome-wide association studies. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34932-z

Pichet Binette, A., Franzmeier, N., Spotorno, N., Ewers, M., Brendel, M., Biel, D., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Shaw, L. M., … Hansson, O. (2022). Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34129-4