Characterizing high-risk enrollment criteria and impact on clinical outcomes in a large randomized clinical trial: Insights from the TWILIGHT trial

Steg, P. G., Nicolas, J., Baber, U., Sartori, S., Zhang, Z., Feng, Y., Angiolillo, D. J., Briguori, C., Cohen, D. J., Collier, T., Dangas, G., Dudek, D., Escaned, J., Gibson, C. M., Han, Y.-L., Huber, K., Kastrati, A., Kaul, U., Marx, S. O., … Mehran, R. (2025). Characterizing high-risk enrollment criteria and impact on clinical outcomes in a large randomized clinical trial: Insights from the TWILIGHT trial. American Heart Journal. https://doi.org/10.1016/j.ahj.2025.01.016
Authors:
Philippe Gabriel Steg
Johny Nicolas
Usman Baber
Samantha Sartori
Zhongjie Zhang
Yihan Feng
Dominick J Angiolillo
Carlo Briguori
David J Cohen
Timothy Collier
George Dangas
Dariusz Dudek
Javier Escaned
C Michael Gibson
Ya-Ling Han
Kurt Huber
Adnan Kastrati
Upendra Kaul
Steven O Marx
Ran Kornowski
Vijay Kunadian
Birgit Vogel
Angelo Oliva
Shamir R Mehta
David Moliterno
Gennaro Sardella
Mitchell Krucoff
Richard A Shlofmitz
Samin Sharma
Stuart Pocock
Roxana Mehran
Affiliated Authors:
Steven O Marx
Columbia Affiliation:
Author Keywords:
acetylsalicylic acid
insulin
ticagrelor
aspirin
platelet aggregation inhibitors
antithrombocytic agent
acute coronary syndrome
adult
aged
article
atherosclerosis
cardiovascular risk factor
clinical outcome
controlled study
coronary artery disease
diabetes mellitus
female
hazard ratio
heart infarction
human
institutional review
intention to treat analysis
ischemia
kaplan meier method
major clinical study
male
middle aged
multicenter study
peripheral arterial disease
professional standard
randomization
randomized controlled trial
risk factor
st segment elevation myocardial infarction
time of death
adverse event
bleeding
cerebrovascular accident
clinical trial
combination drug therapy
coronary angiography
epidemiology
patient selection
percutaneous coronary intervention
prevention and control
procedures
risk assessment
surgery
therapy
treatment outcome
drug therapy, combination
hemorrhage
humans
myocardial infarction
risk factors
stroke
elink
Publication Type:
Article
Unique ID:
10.1016/j.ahj.2025.01.016
PMID:
39889917
DOI:
10.1016/j.ahj.2025.01.016
Journal:
American Heart Journal
Publication Date:
Data Source:
PubMed
Source Link:
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