iScience

Displaying 1 - 38 of 38
Sharan, K., Brandt, C., Yusuf, M. A., Singh, P., Halder, N., Edwards, M. E., Mangu, S. R., Das, A., Mishra, A., Kumar, S. S., Sharma, A., Gupta, A., Liu, X. S., Guo, E. X., Monani, U. R., Ponnalagu, D., Ivanov, I. I., Lal, G., Clare, S., … Yadav, V. K. (2025). Rapid and relaying deleterious effects of a gastrointestinal pathogen, Citrobacter rodentium, on bone, an extra-intestinal organ. IScience, 28(2), 111802. https://doi.org/10.1016/j.isci.2025.111802
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Jun, H. J., Paulo, J. A., Appleman, V. A., Yaron-Barir, T. M., Johnson, J. L., Yeo, A. T., Rogers, V. A., Kuang, S., Varma, H., Gygi, S. P., Trotman, L. C., & Charest, A. (2024). Pleiotropic tumor suppressive functions of PTEN missense mutations during gliomagenesis. IScience, 27(12), 111278. https://doi.org/10.1016/j.isci.2024.111278
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Siegerist, F., Kliewe, F., Hammer, E., Schakau, P., Chi Soh, J. E., Weber, C., Lindenmeyer, M., Reichelt-Wurm, S., Drenic, V., Chatziantoniou, C., Chadjichristos, C. E., Zhang, Y., Simm, S., Banas, M. C., Nauck, M., Völker, U., & Endlich, N. (2024). The role of the tricellular junction protein ILDR2 in glomerulopathies: Expression patterns and functional insights. IScience, 27(12), 111329. https://doi.org/10.1016/j.isci.2024.111329
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Zarco, N., Dovas, A., de Araujo Farias, V., Nagaiah, N. K. H., Haddock, A., Sims, P. A., Hambardzumyan, D., Meyer, C. T., Canoll, P., Rosenfeld, S. S., & Kenchappa, R. S. (2024). Resistance to spindle inhibitors in glioblastoma depends on STAT3 and therapy induced senescence. IScience, 27(12), 111311. https://doi.org/10.1016/j.isci.2024.111311
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Lemmetyinen, T. T., Viitala, E. W., Wartiovaara, L., Päivinen, P., Virtanen, H. T., Pentinmikko, N., Katajisto, P., Mäkelä, T. P., Wang, T. C., Andressoo, J.-O., & Ollila, S. (2024). Mesenchymal GDNF promotes intestinal enterochromaffin cell differentiation. IScience, 27(12), 111246. https://doi.org/10.1016/j.isci.2024.111246
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Thompson, Z., Anderson, G. A., Hernandez, M., Alfaro Quinde, C., Marchione, A., Rodriguez, M., Gabriel, S., Binder, V., Taylor, A. M., & Kathrein, K. L. (2024). Ing4-deficiency promotes a quiescent yet transcriptionally poised state in hematopoietic stem cells. IScience, 27(8), 110521. https://doi.org/10.1016/j.isci.2024.110521
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Kumar, A., Larrea, D., Pero, M. E., Infante, P., Conenna, M., Shin, G. J., Van Elias, V., Grueber, W. B., Di Marcotullio, L., Area-Gomez, E., & Bartolini, F. (2024). MFN2 coordinates mitochondria motility with α-tubulin acetylation and this regulation is disrupted in CMT2A. IScience, 27(6), 109994. https://doi.org/10.1016/j.isci.2024.109994
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Kundnani, D. L., Yang, T., Gombolay, A. L., Mukherjee, K., Newnam, G., Meers, C., Verma, I., Chhatlani, K., Mehta, Z. H., Mouawad, C., & Storici, F. (2024). Distinct features of ribonucleotides within genomic DNA in Aicardi-Goutières syndrome ortholog mutants of Saccharomyces cerevisiae. IScience, 27(6), 110012. https://doi.org/10.1016/j.isci.2024.110012
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Zheng, S., Thakkar, N., Harris, H. L., Liu, S., Zhang, M., Gerstein, M., Aiden, E. L., Rowley, M. J., Noble, W. S., Gürsoy, G., & Singh, R. (2024). Predicting A/B compartments from histone modifications using deep learning. IScience, 27(5), 109570. https://doi.org/10.1016/j.isci.2024.109570
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Ko, K.-P., Zhang, S., Huang, Y., Kim, B., Zou, G., Jun, S., Zhang, J., Zhao, Y., Martin, C., Dunbar, K. J., Efe, G., Rustgi, A. K., Nakagawa, H., Zhang, H., Liu, Z., & Park, J.-I. (2024). Tumor niche network-defined subtypes predict immunotherapy response of esophageal squamous cell cancer. IScience, 27(5), 109795. https://doi.org/10.1016/j.isci.2024.109795
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Alvaro, A., Piazza, A., Papaleo, S., Perini, M., Pasala, A. R., Panelli, S., Nardi, T., Nodari, R., Sterzi, L., Pagani, C., Merla, C., Castelli, D., Olivieri, E., Bracco, S., Ferrando, M. L., Saluzzo, F., Rimoldi, S. G., Corbella, M., Cavallero, A., … Comandatore, F. (2024). Cultivation and sequencing-free protocol for Serratia marcescens detection and typing. IScience, 27(4), 109402. https://doi.org/10.1016/j.isci.2024.109402
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Feng, W. W., Bang, S., Takacs, E. M., Day, C., Crawford, K. J., Al-Sheyab, R., Almufarrej, D. B., Wells, W., Ilchenko, S., Kasumov, T., Kon, N., Novak, C. M., Gu, W., & Kurokawa, M. (2023). Hepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring. IScience, 26(12), 108405. https://doi.org/10.1016/j.isci.2023.108405
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Wang, Q., Li, Z., Guo, Y., Mellis, I. A., Iketani, S., Liu, M., Yu, J., Valdez, R., Lauring, A. S., Sheng, Z., Gordon, A., Liu, L., & Ho, D. D. (2023). Evolving antibody evasion and receptor affinity of the Omicron BA.2.75 sublineage of SARS-CoV-2. IScience, 26(11), 108254. https://doi.org/10.1016/j.isci.2023.108254
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Chen, F., Köhler, M., Cucun, G., Takamiya, M., Kizil, C., Cosacak, M. I., & Rastegar, S. (2023). sox1a:eGFP transgenic line and single-cell transcriptomics reveal the origin of zebrafish intraspinal serotonergic neurons. IScience, 26(8), 107342. https://doi.org/10.1016/j.isci.2023.107342
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Galli, M., Nodari, R., Perini, M., Luconi, E., Fois, L., Vaglienti, F., Bandi, C., Biganzoli, E., & Comandatore, F. (2023). A spatiotemporal reconstruction of the 1630 plague epidemic in Milan. IScience, 26(5), 106704. https://doi.org/10.1016/j.isci.2023.106704
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Nair, M. S., Ribeiro, R. M., Wang, M., Bowen, A. D., Liu, L., Guo, Y., Chang, J. Y., Wang, P., Sheng, Z., Sobieszczyk, M. E., Perelson, A. S., Huang, Y., & Ho, D. D. (2023). Changes in serum-neutralizing antibody potency and breadth post-SARS-CoV-2 mRNA vaccine boost. IScience, 26(4), 106345. https://doi.org/10.1016/j.isci.2023.106345
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Zubiaga, L., Briand, O., Auger, F., Touche, V., Hubert, T., Thevenet, J., Marciniak, C., Quenon, A., Bonner, C., Peschard, S., Raverdy, V., Daoudi, M., Kerr-Conte, J., Pasquetti, G., Koepsell, H., Zdzieblo, D., Mühlemann, M., Thorens, B., Delzenne, N. D., … Pattou, F. (2023). Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes. IScience, 26(4), 106057. https://doi.org/10.1016/j.isci.2023.106057
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Sukumaran, K., Cardenas-Iniguez, C., Burnor, E., Bottenhorn, K. L., Hackman, D. A., McConnell, R., Berhane, K., Schwartz, J., Chen, J.-C., & Herting, M. M. (2023). Ambient fine particulate exposure and subcortical gray matter microarchitecture in 9- and 10-year-old children across the United States. IScience, 26(3), 106087. https://doi.org/10.1016/j.isci.2023.106087
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Lin, Y.-C., Hua, C.-H., Lu, H.-M., Huang, S.-W., Chen, Y., Tsai, M.-H., Lin, F.-Y., Canoll, P., Chiu, S.-C., Huang, W.-H., Cho, D.-Y., & Jan, C.-I. (2023). CAR-T cells targeting HLA-G as potent therapeutic strategy for EGFR-mutated and overexpressed oral cancer. IScience, 26(3), 106089. https://doi.org/10.1016/j.isci.2023.106089
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Dumitriu, D., Baldwin, E., Coenen, R. J. J., Hammond, L. A., Peterka, D. S., Heilbrun, L., Frye, R. E., Palmer, R., Norrman, H. N., Fridell, A., Remnelius, K. L., Isaksson, J., Austin, C., Curtin, P., Bölte, S., & Arora, M. (2023). Deciduous tooth biomarkers reveal atypical fetal inflammatory regulation in autism spectrum disorder. IScience, 26(3), 106247. https://doi.org/10.1016/j.isci.2023.106247
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Ressler, A. K., Sampaio, G. L. A., Dugger, S. A., Sapir, T., Krizay, D., Boland, M. J., Reiner, O., & Goldstein, D. B. (2023). Evidence of shared transcriptomic dysregulation of HNRNPU-related disorder between human organoids and embryonic mice. IScience, 26(1), 105797. https://doi.org/10.1016/j.isci.2022.105797
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Wang, H., Zeng, C., Luo, G., Sun, Y., Zhang, J., Xu, Z., Guo, Y., Ye, H., Mao, J., Chen, S., Zhang, Y., Zhang, K., Vidal Melo, M. F., & Fang, X. (2022). Macrophage ferroportin serves as a therapeutic target against bacteria-induced acute lung injury by promoting barrier restoration. IScience, 25(12), 105698. https://doi.org/10.1016/j.isci.2022.105698
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McGuirt, A., Pigulevskiy, I., & Sulzer, D. (2022). Developmental regulation of thalamus-driven pauses in striatal cholinergic interneurons. IScience, 25(11), 105332. https://doi.org/10.1016/j.isci.2022.105332
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Vitale, F., Gelinas, J. N., & Cabrera, L. Y. (2022). Neurotechnology: Bridging the dialogue between engineers, material scientists, clinicians, and ethicists. IScience, 25(11), 105432. https://doi.org/10.1016/j.isci.2022.105432
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Kleeman, S. O., Cordioli, M., Timmers, P. R. H. J., Khan, A., Tober-Lau, P., Kurth, F., Demichev, V., Meyer, H. V., Wilson, J. F., Ralser, M., Kiryluk, K., Ganna, A., Baillie, K., & Janowitz, T. (2022). Cystatin C is associated with adverse COVID-19 outcomes in diverse populations. IScience, 25(10), 105040. https://doi.org/10.1016/j.isci.2022.105040
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Qi, L., Chakravarthy, R., Li, M. M., Deng, C.-X., Li, R., & Hu, Y. (2022). Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop. IScience, 25(9), 104944. https://doi.org/10.1016/j.isci.2022.104944
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Serra, C. F. H., Liu, H., Qian, J., Mori, M., Lu, J., & Cardoso, W. V. (2022). Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium. IScience, 25(8), 104751. https://doi.org/10.1016/j.isci.2022.104751
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Bondaruk, J., Jaksik, R., Wang, Z., Cogdell, D., Lee, S., Chen, Y., Dinh, K. N., Majewski, T., Zhang, L., Cao, S., Tian, F., Yao, H., Kuś, P., Chen, H., Weinstein, J. N., Navai, N., Dinney, C., Gao, J., Theodorescu, D., … Czerniak, B. (2022). The origin of bladder cancer from mucosal field effects. IScience, 25(7), 104551. https://doi.org/10.1016/j.isci.2022.104551
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Breton, J. M., Eisner, J. S., Gandhi, V. S., Musick, N., Zhang, A., Long, K. L. P., Perloff, O. S., Hu, K. Y., Pham, C. M., Lalchandani, P., Barraza, M. K., Kantor, B., Kaufer, D., & Ben-Ami Bartal, I. (2022). Neural activation associated with outgroup helping in adolescent rats. IScience, 25(6), 104412. https://doi.org/10.1016/j.isci.2022.104412
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Joseph, L. C., Shi, J., Nguyen, Q. N., Pensiero, V., Goulbourne, C., Bauer, R. C., Zhang, H., & Morrow, J. P. (2022). Combined metabolomic and transcriptomic profiling approaches reveal the cardiac response to high-fat diet. IScience, 25(5), 104184. https://doi.org/10.1016/j.isci.2022.104184
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Price, E. J., Vitale, C. M., Miller, G. W., David, A., Barouki, R., Audouze, K., Walker, D. I., Antignac, J.-P., Coumoul, X., Bessonneau, V., & Klánová, J. (2022). Merging the exposome into an integrated framework for “omics” sciences. IScience, 25(3), 103976. https://doi.org/10.1016/j.isci.2022.103976
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Yang, E. J., Pernice, W. M., & Pon, L. A. (2022). A role for cell polarity in lifespan and mitochondrial quality control in the budding yeast Saccharomyces cerevisiae. IScience, 25(3), 103957. https://doi.org/10.1016/j.isci.2022.103957
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Sahajpal, N. S., Jill Lai, C.-Y., Hastie, A., Mondal, A. K., Dehkordi, S. R., van der Made, C. I., Fedrigo, O., Al-Ajli, F., Jalnapurkar, S., Byrska-Bishop, M., Kanagal-Shamanna, R., Levy, B., Schieck, M., Illig, T., Bacanu, S.-A., Chou, J. S., Randolph, A. G., Rojiani, A. M., Zody, M. C., … Kolhe, R. (2022). Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19. IScience, 25(2), 103760. https://doi.org/10.1016/j.isci.2022.103760
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Li, Z., Chiang, Y., He, M., Worgall, T. S., Zhou, H., & Jiang, X.-C. (2021). Liver sphingomyelin synthase 1 deficiency causes steatosis, steatohepatitis, fibrosis, and tumorigenesis: An effect of glucosylceramide accumulation. IScience, 24(12), 103449. https://doi.org/10.1016/j.isci.2021.103449
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