U01HL120393

NIH – National Heart, Lung, and Blood Institute

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DNA Methylation Signatures of Cardiovascular Health Provide Insights Into Diseases

Carbonneau, M., Li, Y., Qu, Y., Zheng, Y., Wood, A. C., Wang, M., Liu, C., Huan, T., Joehanes, R., Guo, X., Yao, J., Taylor, K. D., Tracy, R. P., Durda, P., Liu, Y., Johnson, W. C., Post, W. S., Blackwell, T., Rotter, J. I., … Ma, J. (2025). DNA Methylation Signatures of Cardiovascular Health Provide Insights Into Diseases. Circulation. https://doi.org/10.1161/circulationaha.124.073181
Authors:
Madeleine Carbonneau
Yi Li
Yishu Qu
Yinan Zheng
Alexis C Wood
Mengyao Wang
Chunyu Liu
Tianxiao Huan
Roby Joehanes
Xiuqing Guo
Jie Yao
Kent D Taylor
Russell P Tracy
Peter Durda
Yongmei Liu
W Craig Johnson
Wendy S Post
Tom Blackwell
Jerome I Rotter
Stephen S Rich
Susan Redline
Myriam Fornage
Jun Wang
Hongyan Ning
Lifang Hou
Donald Lloyd-Jones
Kendra Ferrier
Yuan-I Min
April P Carson
Laura M Raffield
Alexander Teumer
Hans J Grabe
Henry Völzke
Matthias Nauck
Marcus Dörr
Arce Domingo-Relloso
Amanda Fretts
Maria Tellez-Plaza
Shelley A Cole
Ana Navas-Acien
Meng Wang
Joanne M Murabito
Nancy L Heard-Costa
Brenton Prescott
Vanessa Xanthakis
Dariush Mozaffarian
Daniel Levy
Jiantao Ma
Affiliated Authors:
Arce Domingo-Relloso
Columbia Affiliation:
Author Keywords:
all-cause mortality
cardiovascular diseases
cardiovascular health
dna methylation
epigenome-wide association study
life’s essential 8
c reactive protein
hemoglobin a1c
guanine
methylationepic
high density lipoprotein
triacylglycerol
microrna
sterol regulatory element binding protein 1
adult
all cause mortality
alzheimer disease
article
atrial fibrillation
bioinformatics
blood analysis
breast cancer
cardiovascular disease
cerebrovascular accident
chronic obstructive lung disease
clinical outcome
cohort analysis
data processing
diastolic blood pressure
female
gene ontology
genome-wide association study
gestational diabetes
health
heart failure
human
hypertension
inflammation
kegg
leukocyte
lung cancer
major clinical study
male
maternal hypertension
medical record
mendelian randomization analysis
monocyte
neutrophil
pathway enrichment analysis
phenotype
physician
preeclampsia
quantitative analysis
single nucleotide polymorphism
systolic blood pressure
aged
cardiovascular mortality
epigenome
false discovery rate
ischemic heart disease
life's essential 8
Grants:
K22HL135075 (NIH – National Heart Lung and Blood Institute)
P30DK063491 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30ES009089 (NIH – National Institute of Environmental Health Sciences)
P42ES033719 (NIH – National Institute of Environmental Health Sciences)
R01AA028263 (NIH – National Institute on Alcohol Abuse and Alcoholism)
R01ES021367 (NIH – National Institute of Environmental Health Sciences)
R01ES025216 (NIH – National Institute of Environmental Health Sciences)
R01ES032638 (NIH – National Institute of Environmental Health Sciences)
R01HL064278 (NIH – National Heart Lung and Blood Institute)
R01HL090863 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R01HL109282 (NIH – National Heart, Lung, and Blood Institute)
R01HL109284 (NIH – National Heart, Lung, and Blood Institute)
R01HL109301 (NIH – National Heart, Lung, and Blood Institute)
R01HL109315 (NIH – National Heart, Lung, and Blood Institute)
R01HL109319 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
U01HL041642 (NIH – National Heart, Lung, and Blood Institute)
U01HL041652 (NIH – National Heart, Lung, and Blood Institute)
U01HL041654 (NIH – National Heart, Lung, and Blood Institute)
U01HL065520 (NIH – National Heart, Lung, and Blood Institute)
U01HL065521 (NIH – National Heart, Lung, and Blood Institute)
U01HL117626 (NIH – National Heart Lung and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
U54HG003067 (NIH – National Human Genome Research Institute)
UL1TR000040 (NIH – National Center for Advancing Translational Sciences)
UL1TR001079 (NIH – National Center for Advancing Translational Sciences)
UL1TR001420 (NIH – National Center for Advancing Translational Sciences)
UL1TR001881 (NIH – National Center for Advancing Translational Sciences)
ZIAHL006001 (NIH – National Heart, Lung, and Blood Institute)
Publication Type:
Article
Unique ID:
10.1161/circulationaha.124.073181
PMID:
40654086
DOI:
10.1161/circulationaha.124.073181
Journal:
Circulation
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Web of Science Record
View Scopus Record

Record Created:

Single-Ancestry versus Multi-Ancestry Polygenic Risk Scores for CKD in Black American Populations

Jones, A. C., Patki, A., Srinivasasainagendra, V., Tiwari, H. K., Armstrong, N. D., Chaudhary, N. S., Limdi, N. A., Hidalgo, B. A., Davis, B., Cimino, J. J., Khan, A., Kiryluk, K., Lange, L. A., Lange, E. M., Arnett, D. K., Young, B. A., Diamantidis, C. J., Franceschini, N., Wassertheil-Smoller, S., … Irvin, M. R. (2024). Single-Ancestry versus Multi-Ancestry Polygenic Risk Scores for CKD in Black American Populations. Journal of the American Society of Nephrology. https://doi.org/10.1681/asn.0000000000000437
Authors:
Alana C Jones
Amit Patki
Vinodh Srinivasasainagendra
Hemant K Tiwari
Nicole D Armstrong
Ninad S Chaudhary
Nita A Limdi
Bertha A Hidalgo
Brittney Davis
James J Cimino
Atlas Khan
Krzysztof Kiryluk
Leslie A Lange
Ethan M Lange
Donna K Arnett
Bessie A Young
Clarissa J Diamantidis
Nora Franceschini
Sylvia Wassertheil-Smoller
Stephen S Rich
Jerome I Rotter
Josyf C Mychaleckyj
Holly J Kramer
Yii-Der I Chen
Bruce M Psaty
Jennifer A Brody
Ian H de Boer
Nisha Bansal
Joshua C Bis
Marguerite R Irvin
Affiliated Authors:
Atlas Khan
Krzysztof Kiryluk
Columbia Affiliation:
Author Keywords:
ckd clinical epidemiology human genetics minority health and disparities
Grants:
UL1TR001881 (NIH – National Center for Advancing Translational Sciences)
UL1TR001079 (NIH – National Center for Advancing Translational Sciences)
UL1TR001420 (NIH – National Center for Advancing Translational Sciences)
UL1TR000040 (NIH – National Center for Advancing Translational Sciences)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL055673 (NIH – National Heart, Lung, and Blood Institute)
R01HL095163 (NIH – National Heart, Lung, and Blood Institute)
U01HL130114 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
R01HL163972 (NIH – National Heart, Lung, and Blood Institute)
R44HL095169 (NIH – National Heart, Lung, and Blood Institute)
R01HL085083 (NIH – National Heart, Lung, and Blood Institute)
K24HL133373 (NIH – National Heart, Lung, and Blood Institute)
R35HL155466 (NIH – National Heart, Lung, and Blood Institute)
R01HL136666 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL092173 (NIH – National Heart, Lung, and Blood Institute)
R43HL095160 (NIH – National Heart, Lung, and Blood Institute)
R43HL095167 (NIH – National Heart, Lung, and Blood Institute)
R21HL095165 (NIH – National Heart, Lung, and Blood Institute)
R43HL095169 (NIH – National Heart, Lung, and Blood Institute)
R43HL095161 (NIH – National Heart, Lung, and Blood Institute)
R13HL095166 (NIH – National Heart, Lung, and Blood Institute)
U01HG011167 (NIH – National Human Genome Research Institute)
U54HG003067 (NIH – National Human Genome Research Institute)
R01DK117445 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
T32DK116672 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30DK063491 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
K26DK138425 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
F31DK128990 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
U01NS041588 (NIH – National Institute of Neurological Disorders and Stroke)
R01AG023629 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1681/asn.0000000000000437
PMID:
39073889
DOI:
10.1681/asn.0000000000000437
Journal:
Journal of the American Society of Nephrology
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record

Record Created:

Genome sequence analyses identify novel risk loci for multiple system atrophy

Chia, R., Ray, A., Shah, Z., Ding, J., Ruffo, P., Fujita, M., Menon, V., Saez-Atienzar, S., Reho, P., Kaivola, K., Walton, R. L., Reynolds, R. H., Karra, R., Sait, S., Akcimen, F., Diez-Fairen, M., Alvarez, I., Fanciulli, A., Stefanova, N., … Scholz, S. W. (2024). Genome sequence analyses identify novel risk loci for multiple system atrophy. Neuron, 112(13), 2142-2156.e5. https://doi.org/10.1016/j.neuron.2024.04.002
Authors:
Ruth Chia
Anindita Ray
Zalak Shah
Jinhui Ding
Paola Ruffo
Masashi Fujita
Vilas Menon
Sara Saez-Atienzar
Paolo Reho
Karri Kaivola
Ronald L Walton
Regina H Reynolds
Ramita Karra
Shaimaa Sait
Fulya Akcimen
Monica Diez-Fairen
Ignacio Alvarez
Alessandra Fanciulli
Nadia Stefanova
Klaus Seppi
Susanne Duerr
Fabian Leys
Florian Krismer
Victoria Sidoroff
Alexander Zimprich
Walter Pirker
Olivier Rascol
Alexandra Foubert-Samier
Wassilios G Meissner
François Tison
Anne Pavy-Le Traon
Maria Teresa Pellecchia
Paolo Barone
Maria Claudia Russillo
Juan Marín-Lahoz
Jaime Kulisevsky
Soraya Torres
Pablo Mir
Maria Teresa Periñán
Christos Proukakis
Viorica Chelban
Lesley Wu
Yee Y Goh
Laura Parkkinen
Michele T Hu
Christopher Kobylecki
Jennifer A Saxon
Sara Rollinson
Emily Garland
Italo Biaggioni
Irene Litvan
Ileana Rubio
Roy N Alcalay
Kimberly T Kwei
Steven J Lubbe
Qinwen Mao
Margaret E Flanagan
Rudolph J Castellani
Vikram Khurana
Alain Ndayisaba
Andrea Calvo
Gabriele Mora
Antonio Canosa
Gianluca Floris
Ryan C Bohannan
Anni Moore
Lucy Norcliffe-Kaufmann
Jose-Alberto Palma
Horacio Kaufmann
Changyoun Kim
Michiyo Iba
Eliezer Masliah
Ted M Dawson
Liana S Rosenthal
Alexander Pantelyat
Marilyn S Albert
Olga Pletnikova
Juan C Troncoso
Jon Infante
Carmen Lage
Pascual Sánchez-Juan
Geidy E Serrano
Thomas G Beach
Pau Pastor
Huw R Morris
Diego Albani
Jordi Clarimon
Gregor K Wenning
John A Hardy
Mina Ryten
Eric Topol
Ali Torkamani
Adriano Chiò
David A Bennett
Philip L De Jager
Philip A Low
Wolfgang Singer
William P Cheshire
Zbigniew K Wszolek
Dennis W Dickson
Bryan J Traynor
J Raphael Gibbs
Clifton L Dalgard
Owen A Ross
Henry Houlden
Sonja W Scholz
Affiliated Authors:
Masashi Fujita
Vilas Menon
Roy N Alcalay
Kimberly T Kwei
Philip L De Jager
Columbia Affiliation:
Subjects:
Pathophysiology of Parkinson's Disease (OpenAlex Topic)
Nurr1/CoREST Pathway in Neuroprotection and Inflammation (OpenAlex Topic)
Neurodegeneration with Brain Iron Accumulation (OpenAlex Topic)
Multiple System Atrophy (MeSH)
Genome-Wide Association Study (MeSH)
Genetic Predisposition to Disease (MeSH)
Author Keywords:
colocalization
gene-burden analysis
genome-wide association study
gwas
msa
multiple system atrophy
pathway analysis
repeat expansion mapping
transcriptome-wide association study
twas
whole genome sequencing
Grants:
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
U24NS072026 (NIH – National Institute of Neurological Disorders and Stroke)
P50NS038377 (NIH – National Institute of Neurological Disorders and Stroke)
ZIANS003154 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS109209 (NIH – National Institute of Neurological Disorders and Stroke)
P30AG019610 (NIH – National Institute On Aging)
P30AG072980 (NIH – National Institute On Aging)
U19AG063911 (NIH – National Institute On Aging)
ZIAAG000936 (NIH – National Institute On Aging)
U01AG061356 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1016/j.neuron.2024.04.002
PMID:
38701790
DOI:
10.1016/j.neuron.2024.04.002
Journal:
Neuron
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
View OpenAlex Record

Record Created:

Peripheral Blood Mononuclear Cell Gene Expression Associated with Pulmonary Microvascular Perfusion: The Multi-Ethnic Study of Atherosclerosis Chronic Obstructive Pulmonary Disease

Buschur, K. L., Pottinger, T. D., Vogel-Claussen, J., Powell, C. A., Aguet, F., Allen, N. B., Ardlie, K., Bluemke, D. A., Durda, P., Hermann, E. A., Hoffman, E. A., Lima, J. A. C., Liu, Y., Malinsky, D., Manichaikul, A., Motahari, A., Post, W. S., Prince, M. R., Rich, S. S., … Barr, R. G. (2024). Peripheral Blood Mononuclear Cell Gene Expression Associated with Pulmonary Microvascular Perfusion: The Multi-Ethnic Study of Atherosclerosis Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society, 21(6), 884–894. https://doi.org/10.1513/annalsats.202305-417oc
Authors:
Kristina L Buschur
Tess D Pottinger
Jens Vogel-Claussen
Charles A Powell
Francois Aguet
Norrina B Allen
Kristin Ardlie
David A Bluemke
Peter Durda
Emilia A Hermann
Eric A Hoffman
João A C Lima
Yongmei Liu
Daniel Malinsky
Ani Manichaikul
Amin Motahari
Wendy S Post
Martin R Prince
Stephen S Rich
Jerome I Rotter
Benjamin M Smith
Russell P Tracy
Karol Watson
Hinrich B Winther
Tuuli Lappalainen
R Graham Barr
Affiliated Authors:
Tuuli Lappalainen
Columbia Affiliation:
Subjects:
Leukocytes, Mononuclear (MeSH)
Pulmonary Disease, Chronic Obstructive (MeSH)
Magnetic Resonance Imaging (MeSH)
Author Keywords:
copd
gene expression
pulmonary microvascular perfusion
Grants:
UL1TR001420 (NIH – National Center for Advancing Translational Sciences)
UL1TR001881 (NIH – National Center for Advancing Translational Sciences)
UL1TR001079 (NIH – National Center for Advancing Translational Sciences)
T32HL144442 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
R01HL077612 (NIH – National Heart, Lung, and Blood Institute)
R44HL095169 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R01HL095163 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL093081 (NIH – National Heart, Lung, and Blood Institute)
R43HL095160 (NIH – National Heart, Lung, and Blood Institute)
R43HL095161 (NIH – National Heart, Lung, and Blood Institute)
R21HL095165 (NIH – National Heart, Lung, and Blood Institute)
R13HL095166 (NIH – National Heart, Lung, and Blood Institute)
R43HL095169 (NIH – National Heart, Lung, and Blood Institute)
R43HL095167 (NIH – National Heart, Lung, and Blood Institute)
U54HG003067 (NIH – National Human Genome Research Institute)
P30DK063491 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
Publication Type:
Article
Unique ID:
10.1513/annalsats.202305-417oc
PMID:
38335160
DOI:
10.1513/annalsats.202305-417oc
Journal:
Annals of the American Thoracic Society
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
View Web of Science Record

Record Created:

Genetic regulators of sputum mucin concentration and their associations with COPD phenotypes

Van Buren, E., Radicioni, G., Lester, S., O’Neal, W. K., Dang, H., Kasela, S., Garudadri, S., Curtis, J. L., Han, M. K., Krishnan, J. A., Wan, E. S., Silverman, E. K., Hastie, A., Ortega, V. E., Lappalainen, T., Nawijn, M. C., Berge, M. van den, Christenson, S. A., Li, Y., … Kelada, S. N. P. (2023). Genetic regulators of sputum mucin concentration and their associations with COPD phenotypes. PLOS Genetics, 19(6), e1010445. https://doi.org/10.1371/journal.pgen.1010445
Authors:
Eric Van Buren
Giorgia Radicioni
Sarah Lester
Wanda K O'Neal
Hong Dang
Silva Kasela
Suresh Garudadri
Jeffrey L Curtis
MeiLan K Han
Jerry A Krishnan
Emily S Wan
Edwin K Silverman
Annette Hastie
Victor E Ortega
Tuuli Lappalainen
Martijn C Nawijn
Maarten van den Berge
Stephanie A Christenson
Yun Li
Michael H Cho
Mehmet Kesimer
Samir N P Kelada
Affiliated Authors:
Silva Kasela
Tuuli Lappalainen
Columbia Affiliation:
Subjects:
Mucins (MeSH)
Pulmonary Disease, Chronic Obstructive (MeSH)
Grants:
R01HL122711 (NIH – National Heart Lung and Blood Institute)
U01DA052713 (NIH – National Institute on Drug Abuse)
P30ES010126 (NIH – National Institute of Environmental Health Sciences)
R01HL089856 (NIH – National Heart, Lung, and Blood Institute)
R01HL110906 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL142028 (NIH – National Heart, Lung, and Blood Institute)
U01HL089856 (NIH – National Heart, Lung, and Blood Institute)
U01HL089897 (NIH – National Heart, Lung, and Blood Institute)
U01HL117626 (NIH – National Heart Lung and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
U01HL137880 (NIH – National Heart, Lung, and Blood Institute)
U24HL141762 (NIH – National Heart, Lung, and Blood Institute)
Publication Type:
Article
Unique ID:
10.1371/journal.pgen.1010445
PMID:
37352370
DOI:
10.1371/journal.pgen.1010445
Journal:
PLOS Genetics
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created:

MUC5B, telomere length and longitudinal quantitative interstitial lung changes: the MESA Lung Study

Kim, J. S., Manichaikul, A. W., Hoffman, E. A., Balte, P., Anderson, M. R., Bernstein, E. J., Madahar, P., Oelsner, E. C., Kawut, S. M., Wysoczanski, A., Laine, A. F., Adegunsoye, A., Ma, J. Z., Taub, M. A., Mathias, R. A., Rich, S. S., Rotter, J. I., Noth, I., Garcia, C. K., … Podolanczuk, A. J. (2022). MUC5B, telomere length and longitudinal quantitative interstitial lung changes: the MESA Lung Study. Thorax, 78(6), 566–573. https://doi.org/10.1136/thorax-2021-218139
Authors:
John S Kim
Ani W Manichaikul
Eric A Hoffman
Pallavi Balte
Michaela R Anderson
Elana J Bernstein
Purnema Madahar
Elizabeth C Oelsner
Steven M Kawut
Artur Wysoczanski
Andrew F Laine
Ayodeji Adegunsoye
Jennie Z Ma
Margaret A Taub
Rasika A Mathias
Stephen S Rich
Jerome I Rotter
Imre Noth
Christine Kim Garcia
R Graham Barr
Anna J Podolanczuk
Affiliated Authors:
John S Kim
Pallavi Balte
Michaela R Anderson
Elana J Bernstein
Purnema Madahar
Elizabeth C Oelsner
Artur Wysoczanski
Andrew F Laine
Christine Kim Garcia
R Graham Barr
Columbia Affiliation:
Subjects:
Standardisation and Management of COPD (OpenAlex Topic)
Malignant Pleural Mesothelioma Research (OpenAlex Topic)
Idiopathic Pulmonary Fibrosis: Diagnosis and Management (OpenAlex Topic)
Lung (MeSH)
Lung Diseases, Interstitial (MeSH)
Author Keywords:
imaging
ct mri etc
interstitial fibrosis
imaging/ct mri etc
Grants:
UL1TR000040 (NIH – National Center for Advancing Translational Sciences)
UL1TR001881 (NIH – National Center for Advancing Translational Sciences)
UL1TR001079 (NIH – National Center for Advancing Translational Sciences)
UL1TR001420 (NIH – National Center for Advancing Translational Sciences)
R01HL077612 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL131565 (NIH – National Heart, Lung, and Blood Institute)
R01HL121270 (NIH – National Heart, Lung, and Blood Institute)
R01HL093081 (NIH – National Heart, Lung, and Blood Institute)
K23HL150301 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
K23HL140199 (NIH – National Heart, Lung, and Blood Institute)
R44HL095169 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
R01HL095163 (NIH – National Heart, Lung, and Blood Institute)
R43HL095169 (NIH – National Heart, Lung, and Blood Institute)
R43HL095161 (NIH – National Heart, Lung, and Blood Institute)
R43HL095167 (NIH – National Heart, Lung, and Blood Institute)
R21HL095165 (NIH – National Heart, Lung, and Blood Institute)
R13HL095166 (NIH – National Heart, Lung, and Blood Institute)
R43HL095160 (NIH – National Heart, Lung, and Blood Institute)
U54HG003067 (NIH – National Human Genome Research Institute)
K23AR075112 (NIH – National Institute of Arthritis and Musculoskeletal and Skin Diseases)
P30DK063491 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30ES005605 (NIH – National Institute of Environmental Health Sciences)
Publication Type:
Article
Unique ID:
10.1136/thorax-2021-218139
PMID:
36690926
DOI:
10.1136/thorax-2021-218139
Journal:
Thorax
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
View OpenAlex Record
View Web of Science Record

Record Created:

Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare Variants

Peljto, A. L., Blumhagen, R. Z., Walts, A. D., Cardwell, J., Powers, J., Corte, T. J., Dickinson, J. L., Glaspole, I., Moodley, Y. P., Vasakova, M. K., Bendstrup, E., Davidsen, J. R., Borie, R., Crestani, B., Dieude, P., Bonella, F., Costabel, U., Gudmundsson, G., Donnelly, S. C., … Schwartz, D. A. (2023). Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare Variants. American Journal of Respiratory and Critical Care Medicine, 207(9), 1194–1202. https://doi.org/10.1164/rccm.202207-1331oc
Authors:
Anna L Peljto
Rachel Z Blumhagen
Avram D Walts
Jonathan Cardwell
Julia Powers
Tamera J Corte
Joanne L Dickinson
Ian Glaspole
Yuben P Moodley
Martina Koziar Vasakova
Elisabeth Bendstrup
Jesper R Davidsen
Raphael Borie
Bruno Crestani
Philippe Dieude
Francesco Bonella
Ulrich Costabel
Gunnar Gudmundsson
Seamas C Donnelly
Jim Egan
Michael T Henry
Michael P Keane
Marcus P Kennedy
Cormac McCarthy
Aoife N McElroy
Joshua A Olaniyi
Katherine M A O'Reilly
Luca Richeldi
Paolo M Leone
Venerino Poletti
Francesco Puppo
Sara Tomassetti
Valentina Luzzi
Nurdan Kokturk
Nesrin Mogulkoc
Christine A Fiddler
Nikhil Hirani
R Gisli Jenkins
Toby M Maher
Philip L Molyneaux
Helen Parfrey
Rebecca Braybrooke
Timothy S Blackwell
Peter D Jackson
Steven D Nathan
Mary K Porteous
Kevin K Brown
Jason D Christie
Harold R Collard
Oliver Eickelberg
Elena E Foster
Kevin F Gibson
Marilyn Glassberg
Daniel J Kass
Jonathan A Kropski
David Lederer
Angela L Linderholm
Jim Loyd
Susan K Mathai
Sydney B Montesi
Imre Noth
Justin M Oldham
Amy J Palmisciano
Cristina A Reichner
Mauricio Rojas
Jesse Roman
Neil Schluger
Barry S Shea
Jeffrey J Swigris
Paul J Wolters
Yingze Zhang
Cecilia M A Prele
Juan I Enghelmayer
Maria Otaola
Christopher J Ryerson
Mauricio Salinas
Martina Sterclova
Tewodros H Gebremariam
Marjukka Myllärniemi
Roberto G Carbone
Haruhiko Furusawa
Masaki Hirose
Yoshikazu Inoue
Yasunari Miyazaki
Ken Ohta
Shin Ohta
Tsukasa Okamoto
Dong Soon Kim
Annie Pardo
Moises Selman
Alvaro U Aranda
Moo Suk Park
Jong Sun Park
Jin Woo Song
Maria Molina-Molina
Lurdes Planas-Cerezales
Gunilla Westergren-Thorsson
Albert V Smith
Ani W Manichaikul
John S Kim
Stephen S Rich
Elizabeth C Oelsner
R Graham Barr
Jerome I Rotter
Josee Dupuis
George O'Connor
Ramachandran S Vasan
Michael H Cho
Edwin K Silverman
Marvin I Schwarz
Mark P Steele
Joyce S Lee
Ivana V Yang
Tasha E Fingerlin
David A Schwartz
Affiliated Authors:
Neil Schluger
Elizabeth C Oelsner
R Graham Barr
Columbia Affiliation:
Subjects:
Idiopathic Pulmonary Fibrosis (MeSH)
Author Keywords:
genetic association studies
interstitial lung disease
telomerase
topmed
whole-genome sequencing
Grants:
UL1TR000040 (NIH – National Center for Advancing Translational Sciences)
UL1TR001079 (NIH – National Center for Advancing Translational Sciences)
UL1TR001881 (NIH – National Center for Advancing Translational Sciences)
UL1TR001420 (NIH – National Center for Advancing Translational Sciences)
UH3HL123442 (NIH – National Heart, Lung, and Blood Institute)
R21HL153700 (NIH – National Heart, Lung, and Blood Institute)
U01HL089897 (NIH – National Heart, Lung, and Blood Institute)
UH2HL123442 (NIH – National Heart, Lung, and Blood Institute)
P01HL092870 (NIH – National Heart, Lung, and Blood Institute)
R44HL095169 (NIH – National Heart, Lung, and Blood Institute)
R01HL158668 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL145372 (NIH – National Heart, Lung, and Blood Institute)
R21HL129924 (NIH – National Heart, Lung, and Blood Institute)
U01HL089856 (NIH – National Heart, Lung, and Blood Institute)
K23HL130627 (NIH – National Heart, Lung, and Blood Institute)
R01HL149836 (NIH – National Heart, Lung, and Blood Institute)
R01HL095163 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL092577 (NIH – National Heart, Lung, and Blood Institute)
K23HL150331 (NIH – National Heart, Lung, and Blood Institute)
UG3HL151865 (NIH – National Heart, Lung, and Blood Institute)
UH3HL151865 (NIH – National Heart, Lung, and Blood Institute)
R43HL095167 (NIH – National Heart, Lung, and Blood Institute)
R13HL095166 (NIH – National Heart, Lung, and Blood Institute)
R43HL095160 (NIH – National Heart, Lung, and Blood Institute)
R43HL095161 (NIH – National Heart, Lung, and Blood Institute)
R43HL095169 (NIH – National Heart, Lung, and Blood Institute)
R21HL095165 (NIH – National Heart, Lung, and Blood Institute)
U54HG003067 (NIH – National Human Genome Research Institute)
P30DK063491 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30ES013508 (NIH – National Institute of Environmental Health Sciences)
I01BX005295 (NIH – Veterans Affairs)
Publication Type:
Article
Unique ID:
10.1164/rccm.202207-1331oc
PMID:
36602845
DOI:
10.1164/rccm.202207-1331oc
Journal:
American Journal of Respiratory and Critical Care Medicine
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record

Record Created:

Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants

Young, K. L., Fisher, V., Deng, X., Brody, J. A., Graff, M., Lim, E., Lin, B. M., Xu, H., Amin, N., An, P., Aslibekyan, S., Fohner, A. E., Hidalgo, B., Lenzini, P., Kraaij, R., Medina-Gomez, C., Prokić, I., Rivadeneira, F., Sitlani, C., … Liu, C.-T. (2023). Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants. Human Genetics and Genomics Advances, 4(1), 100163. https://doi.org/10.1016/j.xhgg.2022.100163
Authors:
Kristin L. Young
Misa Graff
Kari E. North
Virginia Fisher
Xuan Deng
Elise Lim
Hanfei Xu
L. Adrienne Cupples
Ching-Ti Liu
Jennifer A. Brody
Colleen Sitlani
Bridget M. Lin
Danyu Lin
Najaf Amin
Ivana Prokic
Ping An
Petra Lenzini
Michael Province
Stella Aslibekyan
Bertha Hidalgo
Marguerite R. Irvin
Alison E. Fohner
Alexander P. Reiner
Robert Kraaij
Carolina Medina-Gomez
Fernando Rivadeneira
Jeroen van Rooij
Ran Tao
Di Zhang
Jai G. Broome
Erin J. Buth
Benjamin D. Heavner
Deepti Jain
Barbara McKnight
Kathleen Barnes
Meher Preethi Boorgula
Sameer Chavan
Dawood Darbar
Mariza De Andrade
Xiuqing Guo
Jerome I. Rotter
Jeffrey Haessler
Charles Kooperberg
Rita R. Kalyani
Sharon L. R. Kardia
Patricia A. Peyser
Jennifer A. Smith
Wonji Kim
Scott Weiss
Rasika A. Mathias
Merry-Lynn McDonald
Braxton D. Mitchell
Elizabeth A. Regan
Susan Redline
Stephen S. Rich
Kerri L. Wiggins
Lisa R. Yanek
Donna Arnett
Nancy L. Heard-Costa
Suzanne Leal
Cornelia M. van Duijn
Affiliated Authors:
Suzanne Leal
Columbia Affiliation:
Grants:
KL2TR001109 (NIH – National Center for Advancing Translational Sciences)
R01HL131136 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R21HL140419 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R01HL153460 (NIH – National Heart, Lung, and Blood Institute)
R01HL149683 (NIH – National Heart, Lung, and Blood Institute)
RC2HL102419 (NIH – National Heart, Lung, and Blood Institute)
U54HG003273 (NIH – National Human Genome Research Institute)
UM1HG008898 (NIH – National Human Genome Research Institute)
R01HG009974 (NIH – National Human Genome Research Institute)
R01DK122503 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK089256 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
Publication Type:
Article
Unique ID:
10.1016/j.xhgg.2022.100163
PMID:
36568030
DOI:
10.1016/j.xhgg.2022.100163
Journal:
Human Genetics and Genomics Advances
Publication Date:
Data Source:
Web of Science
Source Link:
View Web of Science Record

Record Created:

Rare coding variants in RCN3 are associated with blood pressure

He, K. Y., Kelly, T. N., Wang, H., Liang, J., Zhu, L., Cade, B. E., Assimes, T. L., Becker, L. C., Beitelshees, A. L., Bielak, L. F., Bress, A. P., Brody, J. A., Chang, Y.-P. C., Chang, Y.-C., de Vries, P. S., Duggirala, R., Fox, E. R., Franceschini, N., Furniss, A. L., … Zhu, X. (2022). Rare coding variants in RCN3 are associated with blood pressure. BMC Genomics, 23(1). https://doi.org/10.1186/s12864-022-08356-4
Authors:
Karen Y. He
Tanika N. Kelly
Heming Wang
Jingjing Liang
Luke Zhu
Brian E. Cade
Themistocles L. Assimes
Lewis C. Becker
Amber L. Beitelshees
Lawrence F. Bielak
Adam P. Bress
Jennifer A. Brody
Yen-Pei Christy Chang
Yi-Cheng Chang
Paul S. de Vries
Ravindranath Duggirala
Ervin R. Fox
Nora Franceschini
Anna L. Furniss
Yan Gao
Xiuqing Guo
Jeffrey Haessler
Yi-Jen Hung
Shih-Jen Hwang
Marguerite Ryan Irvin
Rita R. Kalyani
Ching-Ti Liu
Chunyu Liu
Lisa Warsinger Martin
May E. Montasser
Paul M. Muntner
Stanford Mwasongwe
Take Naseri
Walter Palmas
Muagututi’a Sefuiva Reupena
Kenneth M. Rice
Wayne H.-H. Sheu
Daichi Shimbo
Jennifer A. Smith
Beverly M. Snively
Lisa R. Yanek
Wei Zhao
John Blangero
Eric Boerwinkle
Yii-Der Ida Chen
Adolfo Correa
L. Adrienne Cupples
Joanne E. Curran
Myriam Fornage
Jiang He
Lifang Hou
Robert C. Kaplan
Sharon L. R. Kardia
Eimear E. Kenny
Charles Kooperberg
Donald Lloyd-Jones
Ruth J. F. Loos
Rasika A. Mathias
Stephen T. McGarvey
Braxton D. Mitchell
Kari E. North
Patricia A. Peyser
Bruce M. Psaty
Laura M. Raffield
D.C. Rao
Susan Redline
Alex P. Reiner
Stephen S. Rich
Jerome I. Rotter
Kent D. Taylor
Russell Tracy
Ramachandran S. Vasan
Alanna C. Morrison
Daniel Levy
Aravinda Chakravarti
Donna K. Arnett
Xiaofeng Zhu
Affiliated Authors:
Walter Palmas
Daichi Shimbo
Columbia Affiliation:
Subjects:
Genome-Wide Association Study (MeSH)
Precision Medicine (MeSH)
Genomic Studies and Association Analyses (OpenAlex Topic)
Standards and Guidelines for Genetic Variant Interpretation (OpenAlex Topic)
Genetic Research on BRCA Mutations and Cancer Risk (OpenAlex Topic)
Author Keywords:
blood pressure
rare variant analysis
whole genome sequencing
Grants:
UL1TR001079 (NIH – National Center for Advancing Translational Sciences)
UL1TR001420 (NIH – National Center for Advancing Translational Sciences)
UL1TR001881 (NIH – National Center for Advancing Translational Sciences)
UL1TR000040 (NIH – National Center for Advancing Translational Sciences)
KL2TR002490 (NIH – National Center for Advancing Translational Sciences)
UL1RR033176 (NIH – National Center for Research Resources)
R03HL154284 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
U01HL130114 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R01HL119443 (NIH – National Heart, Lung, and Blood Institute)
R01HL093093 (NIH – National Heart, Lung, and Blood Institute)
R01HL095163 (NIH – National Heart, Lung, and Blood Institute)
R01HL086694 (NIH – National Heart, Lung, and Blood Institute)
P01HL045522 (NIH – National Heart, Lung, and Blood Institute)
R01HL113323 (NIH – National Heart, Lung, and Blood Institute)
R01HL112064 (NIH – National Heart, Lung, and Blood Institute)
R01HL059367 (NIH – National Heart, Lung, and Blood Institute)
R01HL055673 (NIH – National Heart, Lung, and Blood Institute)
R01HL113338 (NIH – National Heart, Lung, and Blood Institute)
R21HL140385 (NIH – National Heart, Lung, and Blood Institute)
R35HL135818 (NIH – National Heart, Lung, and Blood Institute)
R01HL087263 (NIH – National Heart, Lung, and Blood Institute)
R01HL092577 (NIH – National Heart, Lung, and Blood Institute)
R01HL111249 (NIH – National Heart, Lung, and Blood Institute)
R01HL098433 (NIH – National Heart, Lung, and Blood Institute)
R01HL085083 (NIH – National Heart, Lung, and Blood Institute)
K01HL133468 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R44HL095169 (NIH – National Heart, Lung, and Blood Institute)
R01HL121007 (NIH – National Heart, Lung, and Blood Institute)
R01HL133040 (NIH – National Heart, Lung, and Blood Institute)
K01HL135405 (NIH – National Heart, Lung, and Blood Institute)
R01HL131136 (NIH – National Heart, Lung, and Blood Institute)
R01HL153805 (NIH – National Heart, Lung, and Blood Institute)
R01HL090682 (NIH – National Heart, Lung, and Blood Institute)
U01HL065233 (NIH – National Heart, Lung, and Blood Institute)
R43HL095160 (NIH – National Heart, Lung, and Blood Institute)
R43HL095169 (NIH – National Heart, Lung, and Blood Institute)
R01HL087660 (NIH – National Heart, Lung, and Blood Institute)
R01HL088119 (NIH – National Heart, Lung, and Blood Institute)
R13HL095166 (NIH – National Heart, Lung, and Blood Institute)
R43HL095167 (NIH – National Heart, Lung, and Blood Institute)
R21HL095165 (NIH – National Heart, Lung, and Blood Institute)
R43HL095161 (NIH – National Heart, Lung, and Blood Institute)
R01HL087698 (NIH – National Heart, Lung, and Blood Institute)
R56HG010297 (NIH – National Human Genome Research Institute)
U54HG003273 (NIH – National Human Genome Research Institute)
U01HG007417 (NIH – National Human Genome Research Institute)
R01HG003054 (NIH – National Human Genome Research Institute)
U54HG003067 (NIH – National Human Genome Research Institute)
U24HG008956 (NIH – National Human Genome Research Institute)
UM1HG008898 (NIH – National Human Genome Research Institute)
R01HG011052 (NIH – National Human Genome Research Institute)
R01DK110113 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
U01DK085524 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30DK063491 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK117445 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK107786 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30ES000002 (NIH – National Institute of Environmental Health Sciences)
P20GM109036 (NIH – National Institute of General Medical Sciences)
R01MH078143 (NIH – National Institute of Mental Health)
R01MH083824 (NIH – National Institute of Mental Health)
R01MH078111 (NIH – National Institute of Mental Health)
R01AG023629 (NIH – National Institute On Aging)
R01MD012765 (NIH – National Institute On Minority Health and Health Disparities)
Publication Type:
Article
Unique ID:
10.1186/s12864-022-08356-4
PMID:
35183128
DOI:
10.1186/s12864-022-08356-4
Journal:
BMC Genomics
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View OpenAlex Record
View PubMed Record
View Web of Science Record

Record Created:

A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood

Kurniansyah, N., Goodman, M. O., Kelly, T. N., Elfassy, T., Wiggins, K. L., Bis, J. C., Guo, X., Palmas, W., Taylor, K. D., Lin, H. J., Haessler, J., Gao, Y., Shimbo, D., Smith, J. A., Yu, B., Feofanova, E. V., Smit, R. A. J., Wang, Z., Hwang, S.-J., … Sofer, T. (2022). A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31080-2
Authors:
Nuzulul Kurniansyah
Matthew O. Goodman
Tanika N. Kelly
Tali Elfassy
Kerri L. Wiggins
Joshua C. Bis
Xiuqing Guo
Walter Palmas
Kent D. Taylor
Henry J. Lin
Jeffrey Haessler
Yan Gao
Daichi Shimbo
Jennifer A. Smith
Bing Yu
Elena V. Feofanova
Roelof A. J. Smit
Zhe Wang
Shih-Jen Hwang
Simin Liu
Sylvia Wassertheil-Smoller
JoAnn E. Manson
Donald M. Lloyd-Jones
Stephen S. Rich
Ruth J. F. Loos
Susan Redline
Adolfo Correa
Charles Kooperberg
Myriam Fornage
Robert C. Kaplan
Bruce M. Psaty
Jerome I. Rotter
Donna K. Arnett
Alanna C. Morrison
Nora Franceschini
Daniel Levy
Robert C. Kaplan
Jerome I. Rotter
Donna K. Arnett
Tamar Sofer
Affiliated Authors:
Walter Palmas
Daichi Shimbo
Columbia Affiliation:
Subjects:
Genomic Studies and Association Analyses (OpenAlex Topic)
Developmental Origins of Adult Health and Disease (OpenAlex Topic)
Effects of Working Memory Training on Cognitive Abilities (OpenAlex Topic)
Diabetes Mellitus, Type 2 (MeSH)
Hypertension (MeSH)
Grants:
R21HL145425 (NIH – National Heart, Lung, and Blood Institute)
R01HL151152 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R35HL135818 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL117323 (NIH – National Heart, Lung, and Blood Institute)
Publication Type:
Article
Unique ID:
10.1038/s41467-022-31080-2
PMID:
35729114
DOI:
10.1038/s41467-022-31080-2
Journal:
Nature Communications
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View PubMed Record
View OpenAlex Record
View Web of Science Record

Record Created:

Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals

Tahir, U. A., Katz, D. H., Avila-Pachecho, J., Bick, A. G., Pampana, A., Robbins, J. M., Yu, Z., Chen, Z.-Z., Benson, M. D., Cruz, D. E., Ngo, D., Deng, S., Shi, X., Zheng, S., Eisman, A. S., Farrell, L., Hall, M. E., Correa, A., Tracy, R. P., … Gerszten, R. E. (2022). Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32275-3
Authors:
Usman A. Tahir
Daniel H. Katz
Julián Ávila-Pacheco
Alexander G. Bick
Akhil Pampana
Jeremy Robbins
Zhi Yu
Zsu‐Zsu Chen
Mark D. Benson
Daniel E. Cruz
Debby Ngo
Shuliang Deng
Xu Shi
Shuning Zheng
Aaron S. Eisman
Laurie Farrell
Michael E. Hall
Adolfo Correa
Russell P. Tracy
Peter Durda
Kent D. Taylor
Yongmei Liu
W. Craig Johnson
Xiuqing Guo
Jie Yao
Yii‐Der Ida Chen
Ani Manichaikul
Frederick L. Ruberg
William S. Blaner
Deepti Jain
Namiko Abe
Gonçalo R. Abecasis
François Aguet
Christine M. Albert
Laura Almasy
Álvaro Alonso
Seth A. Ament
Peter Anderson
Pramod Anugu
Deborah Applebaum‐Bowden
Kristin Ardlie
Dan E. Arking
Donna K. Arnett
Allison Ashley‐Koch
Stella Aslibekyan
Tim Assimes
Paul L. Auer
Dimitrios Avramopoulos
Najib Ayas
Adithya Balasubramanian
John Barnard
Kathleen C. Barnes
R. Graham Barr
Emily Barron‐Casella
Lucas Barwick
Terri H. Beaty
Gerald J. Beck
Diane M. Becker
Lewis C. Becker
Rebecca Beer
Amber L. Beitelshees
Emelia J. Benjamin
Takis Benos
Marcos Bezerra
Larry Bielak
Joshua C. Bis
Thomas W. Blackwell
John Blangero
Nathan R. Blue
Eric Boerwinkle
Donald W. Bowden
Russell P. Bowler
Jennifer A. Brody
Ulrich Broeckel
Jai Broome
Deborah Brown
Karen Bunting
Esteban G. Burchard
Carlos D. Bustamante
Erin Buth
Brian E. Cade
Jonathan Cardwell
Vincent J. Carey
Julie Carrier
April P. Carson
Cara L. Carty
Richard Casaburi
Juan P. Romero
James F. Casella
Peter J. Castaldi
Mark Chaffin
Christy Chang
Yi‐Cheng Chang
Daniel I. Chasman
Sameer Chavan
Bo‐Juen Chen
Wei‐Min Chen
Michael Cho
Seung Hoan Choi
Lee‐Ming Chuang
Affiliated Authors:
William S. Blaner
Subjects:
Cardiovascular Diseases (MeSH)
Genome-Wide Association Study (MeSH)
Genomic Studies and Association Analyses (OpenAlex Topic)
Role of Homocysteine in Health and Disease (OpenAlex Topic)
RNA Methylation and Modification in Gene Expression (OpenAlex Topic)
Grants:
T32CA154274 (NIH – National Cancer Institute)
UL1TR000040 (NIH – National Center for Advancing Translational Sciences)
KL2TR002542 (NIH – National Center for Advancing Translational Sciences)
UL1TR001079 (NIH – National Center for Advancing Translational Sciences)
UL1TR001881 (NIH – National Center for Advancing Translational Sciences)
UL1TR001420 (NIH – National Center for Advancing Translational Sciences)
R44HL095169 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
R01HL135242 (NIH – National Heart, Lung, and Blood Institute)
R01HL146462 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R01HL151283 (NIH – National Heart, Lung, and Blood Institute)
K08HL141601 (NIH – National Heart, Lung, and Blood Institute)
R01HL148050 (NIH – National Heart, Lung, and Blood Institute)
T32HL007374 (NIH – National Heart, Lung, and Blood Institute)
R01HL142711 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
K23HL150327 (NIH – National Heart, Lung, and Blood Institute)
R01HL148565 (NIH – National Heart, Lung, and Blood Institute)
R01HL095163 (NIH – National Heart, Lung, and Blood Institute)
R01HL127564 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
K08HL145095 (NIH – National Heart, Lung, and Blood Institute)
R01HL151152 (NIH – National Heart, Lung, and Blood Institute)
R01HL139671 (NIH – National Heart, Lung, and Blood Institute)
R43HL095160 (NIH – National Heart, Lung, and Blood Institute)
R43HL095161 (NIH – National Heart, Lung, and Blood Institute)
R01HL045670 (NIH – National Heart, Lung, and Blood Institute)
R13HL095166 (NIH – National Heart, Lung, and Blood Institute)
R43HL095167 (NIH – National Heart, Lung, and Blood Institute)
R21HL095165 (NIH – National Heart, Lung, and Blood Institute)
R43HL095169 (NIH – National Heart, Lung, and Blood Institute)
U54HG003067 (NIH – National Human Genome Research Institute)
R01DK068437 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK122071 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30DK063491 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK081572 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
K23DK127073 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30GM118430 (NIH – National Institute of General Medical Sciences)
R01NR019628 (NIH – National Institute of Nursing Research)
K01AG059898 (NIH – National Institute On Aging)
R21AA028110 (NIH – National Institute On Alcohol Abuse and Alcoholism)
Publication Type:
Article
Unique ID:
10.1038/s41467-022-32275-3
PMID:
35995766
DOI:
10.1038/s41467-022-32275-3
Journal:
Nature Communications
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
View PubMed Record
View Web of Science Record

Record Created:

Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension

Kelly, T. N., Sun, X., He, K. Y., Brown, M. R., Taliun, S. A. G., Hellwege, J. N., Irvin, M. R., Mi, X., Brody, J. A., Franceschini, N., Guo, X., Hwang, S.-J., de Vries, P. S., Gao, Y., Moscati, A., Nadkarni, G. N., Yanek, L. R., Elfassy, T., … Smith, J. A. (2022). Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension. Hypertension, 79(8), 1656–1667. https://doi.org/10.1161/hypertensionaha.122.19324
Authors:
Tanika N. Kelly
Xiao Sun
Karen Y. He
Michael R. Brown
Sarah A. Gagliano Taliun
Jacklyn N. Hellwege
Marguerite R. Irvin
Xuenan Mi
Jennifer A. Brody
Nora Franceschini
Xiuqing Guo
Shih-Jen Hwang
Paul S. De Vries
Yan Gao
Arden Moscati
Girish N. Nadkarni
Lisa R. Yanek
Tali Elfassy
Jennifer A. Smith
Ren-Hua Chung
Amber L. Beitelshees
Amit Patki
Stella Aslibekyan
Brandon M. Blobner
Juan M. Peralta
Themistocles L. Assimes
Walter R. Palmas
Chunyu Liu
Adam P. Bress
Zhijie Huang
Lewis C. Becker
Chii-Min Hwa
Jeffrey R. O'connell
Jenna C. Carlson
Helen R. Warren
Sayantan Das
Ayush Giri
Lisa W. Martin
W. Craig Johnson
Ervin R. Fox
Erwin P. Bottinger
Alexander C. Razavi
Dhananjay Vaidya
Lee-Ming Chuang
Yen-Pei C. Chang
Take Naseri
Deepti Jain
Hyun Min Kang
Adriana M. Hung
Vinodh Srinivasasainagendra
Beverly M. Snively
Dongfeng Gu
May E. Montasser
Muagututi'a Sefuiva Reupena
Benjamin D. Heavner
Jonathon Lefaive
James E. Hixson
Kenneth M. Rice
Fei Fei Wang
Jonas B. Nielsen
Jianfeng Huang
Alyna T. Khan
Wei Zhou
Jovia L. Nierenberg
Cathy C. Laurie
Nicole D. Armstrong
Mengyao Shi
Yang Pan
Adrienne M. Stilp
Leslie Emery
Quenna Wong
Nicola L. Hawley
Ryan L. Minster
Joanne E. Curran
Patricia B. Munroe
Daniel E. Weeks
Kari E. North
Russell P. Tracy
Eimear E. Kenny
Daichi Shimbo
Aravinda Chakravarti
Stephen S. Rich
Alex P. Reiner
John Blangero
Susan Redline
Braxton D. Mitchell
Dabeeru C. Rao
Yii-Der Ida Chen
Sharon L.R. Kardia
Robert C. Kaplan
Rasika A. Mathias
Jiang He
Bruce M. Psaty
Myriam Fornage
Ruth J.F. Loos
Adolfo Correa
Eric Boerwinkle
Jerome I. Rotter
Charles Kooperberg
Todd L. Edwards
Gonçalo R. Abecasis
Xiaofeng Zhu
Daniel Levy
Donna K. Arnett
Alanna C. Morrison
Affiliated Authors:
Walter R. Palmas
Daichi Shimbo
Columbia Affiliation:
Subjects:
Hypertension (MeSH)
Author Keywords:
allele
blood pressure
genome
hypertension
whole genome sequencing
Grants:
K12HD043483 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
T32CA160056 (NIH – National Cancer Institute)
T32CA112355 (NIH – National Cancer Institute)
UL1TR001863 (NIH – National Center for Advancing Translational Sciences)
UL1TR003098 (NIH – National Center for Advancing Translational Sciences)
UL1TR001079 (NIH – National Center for Advancing Translational Sciences)
UL1TR000040 (NIH – National Center for Advancing Translational Sciences)
UL1TR001420 (NIH – National Center for Advancing Translational Sciences)
UL1TR001881 (NIH – National Center for Advancing Translational Sciences)
UL1RR033176 (NIH – National Center for Research Resources)
R01HL090682 (NIH – National Heart, Lung, and Blood Institute)
R01HL098433 (NIH – National Heart, Lung, and Blood Institute)
R01HL095163 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
K01HL133468 (NIH – National Heart, Lung, and Blood Institute)
R21HL121429 (NIH – National Heart, Lung, and Blood Institute)
R01HL112064 (NIH – National Heart, Lung, and Blood Institute)
R01HL119443 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL092577 (NIH – National Heart, Lung, and Blood Institute)
R01HL131136 (NIH – National Heart, Lung, and Blood Institute)
R01HL157635 (NIH – National Heart, Lung, and Blood Institute)
R01HL087263 (NIH – National Heart, Lung, and Blood Institute)
ZIAHL006001 (NIH – National Heart, Lung, and Blood Institute)
R01HL086694 (NIH – National Heart, Lung, and Blood Institute)
R01HL085083 (NIH – National Heart, Lung, and Blood Institute)
U01HL130114 (NIH – National Heart, Lung, and Blood Institute)
R01HL113338 (NIH – National Heart, Lung, and Blood Institute)
R01HL136666 (NIH – National Heart, Lung, and Blood Institute)
R01HL059367 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
R21HL140385 (NIH – National Heart, Lung, and Blood Institute)
R44HL095169 (NIH – National Heart, Lung, and Blood Institute)
R01HL104135 (NIH – National Heart, Lung, and Blood Institute)
R35HL135818 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R01HL055673 (NIH – National Heart, Lung, and Blood Institute)
R01HL111249 (NIH – National Heart, Lung, and Blood Institute)
R01HL121007 (NIH – National Heart, Lung, and Blood Institute)
R01HL133040 (NIH – National Heart, Lung, and Blood Institute)
R01HL093093 (NIH – National Heart, Lung, and Blood Institute)
R13HL095166 (NIH – National Heart, Lung, and Blood Institute)
R43HL095167 (NIH – National Heart, Lung, and Blood Institute)
R43HL095160 (NIH – National Heart, Lung, and Blood Institute)
R43HL095169 (NIH – National Heart, Lung, and Blood Institute)
R43HL095161 (NIH – National Heart, Lung, and Blood Institute)
R01HL087698 (NIH – National Heart, Lung, and Blood Institute)
R21HL095165 (NIH – National Heart, Lung, and Blood Institute)
U01HL065233 (NIH – National Heart, Lung, and Blood Institute)
R01HL088119 (NIH – National Heart, Lung, and Blood Institute)
R01HL087660 (NIH – National Heart, Lung, and Blood Institute)
U01HG007417 (NIH – National Human Genome Research Institute)
UM1HG008898 (NIH – National Human Genome Research Institute)
U54HG003067 (NIH – National Human Genome Research Institute)
R01HG007022 (NIH – National Human Genome Research Institute)
U24HG008956 (NIH – National Human Genome Research Institute)
R56HG010297 (NIH – National Human Genome Research Institute)
U54HG003273 (NIH – National Human Genome Research Institute)
P30DK063491 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK107786 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK110113 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK117445 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P20GM109036 (NIH – National Institute of General Medical Sciences)
U01NS041588 (NIH – National Institute of Neurological Disorders and Stroke)
R01AG023629 (NIH – National Institute On Aging)
R01MD012765 (NIH – National Institute On Minority Health and Health Disparities)
I01BX003360 (NIH – Veterans Affairs)
I01CX001897 (NIH – Veterans Affairs)
Publication Type:
Article
Unique ID:
10.1161/HYPERTENSIONAHA.122.19324
PMID:
35652341
DOI:
10.1161/HYPERTENSIONAHA.122.19324
Journal:
Hypertension
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View Web of Science Record
View PubMed Record

Record Created:

Arsenic Exposure, Blood DNA Methylation, and Cardiovascular Disease

Domingo-Relloso, A., Makhani, K., Riffo-Campos, A. L., Tellez-Plaza, M., Klein, K. O., Subedi, P., Zhao, J., Moon, K. A., Bozack, A. K., Haack, K., Goessler, W., Umans, J. G., Best, L. G., Zhang, Y., Herreros-Martinez, M., Glabonjat, R. A., Schilling, K., Galvez-Fernandez, M., Kent, J. W., … Navas-Acien, A. (2022). Arsenic Exposure, Blood DNA Methylation, and Cardiovascular Disease. Circulation Research, 131(2). https://doi.org/10.1161/circresaha.122.320991
Authors:
Arce Domingo-Relloso
Kiran Makhani
Angela L. Riffo-Campos
Maria Tellez-Plaza
Kathleen Oros Klein
Pooja Subedi
Jinying Zhao
Katherine A. Moon
Anne K. Bozack
Karin Haack
Walter Goessler
Jason G. Umans
Lyle G. Best
Ying Zhang
Miguel Herreros-Martinez
Ronald A. Glabonjat
Kathrin Schilling
Marta Galvez-Fernandez
Jack W. Kent
Tiffany R Sanchez
Kent D. Taylor
W. Craig Johnson
Peter Durda
Russell P. Tracy
Jerome I. Rotter
Stephen S. Rich
David Van Den Berg
Silva Kasela
Tuuli Lappalainen
Ramachandran S Vasan
Roby Joehanes
Barbara V. Howard
Daniel Levy
Kurt Lohman
Yongmei Liu
M Daniele Fallin
Shelley A. Cole
Koren K. Mann
Ana Navas-Acien
Affiliated Authors:
Arce Domingo-Relloso
Ronald A. Glabonjat
Kathrin Schilling
Marta Galvez-Fernandez
Tiffany R Sanchez
Silva Kasela
Ana Navas-Acien
Columbia Affiliation:
Subjects:
Arsenic (MeSH)
Atherosclerosis (MeSH)
Cardiovascular Diseases (MeSH)
Author Keywords:
dna methylation
arsenic
cardiovascular diseases
Grants:
UL1TR000040 (NIH – National Center for Advancing Translational Sciences)
UL1TR001079 (NIH – National Center for Advancing Translational Sciences)
UL1TR001881 (NIH – National Center for Advancing Translational Sciences)
UL1TR001420 (NIH – National Center for Advancing Translational Sciences)
ZIAHL006001 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R01HL146860 (NIH – National Heart, Lung, and Blood Institute)
R01HL095163 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL151855 (NIH – National Heart, Lung, and Blood Institute)
R44HL095169 (NIH – National Heart, Lung, and Blood Institute)
R43HL095167 (NIH – National Heart, Lung, and Blood Institute)
R43HL095169 (NIH – National Heart, Lung, and Blood Institute)
R21HL095165 (NIH – National Heart, Lung, and Blood Institute)
R13HL095166 (NIH – National Heart, Lung, and Blood Institute)
R01ES025216 (NIH – National Institute of Environmental Health Sciences)
P42ES033719 (NIH – National Institute of Environmental Health Sciences)
P42ES010349 (NIH – National Institute of Environmental Health Sciences)
P30ES009089 (NIH – National Institute of Environmental Health Sciences)
R01ES021367 (NIH – National Institute of Environmental Health Sciences)
Publication Type:
Article
Unique ID:
10.1161/CIRCRESAHA.122.320991
PMID:
35658476
DOI:
10.1161/CIRCRESAHA.122.320991
Journal:
Circulation Research
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View Web of Science Record
View PubMed Record

Record Created:

Epigenome-wide association study of mitochondrial genome copy number

Wang, P., Castellani, C. A., Yao, J., Huan, T., Bielak, L. F., Zhao, W., Haessler, J., Joehanes, R., Sun, X., Guo, X., Longchamps, R. J., Manson, J. E., Grove, M. L., Bressler, J., Taylor, K. D., Lappalainen, T., Kasela, S., Van Den Berg, D. J., … Hou, L. (2021). Epigenome-wide association study of mitochondrial genome copy number. Human Molecular Genetics, 31(2), 309–319. https://doi.org/10.1093/hmg/ddab240
Authors:
Penglong Wang
Tianxiao Huan
Roby Joehanes
Daniel Levy
Christina A. Castellani
Ryan J. Longchamps
Dan E. Arking
Kent D. Taylor
Jie Yao
Xiuqing Guo
Jerome Rotter
Lawrence F. Bielak
Wei Zhao
Jennifer A. Smith
Patricia A. Peyser
Jeffrey Haessler
Alexander Reiner
Charles Kooperberg
Xianbang Sun
Chunyu Liu
JoAnn E. Manson
Megan L. Grove
Jan Bressler
Eric Boerwinkle
Myriam Fornage
Tuuli Lappalainen
Silva Kasela
David J. Van den Berg
Lifang Hou
Yongmei Liu
Stephen S. Rich
Affiliated Authors:
Tuuli Lappalainen
Silva Kasela
Columbia Affiliation:
Grants:
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R01HL133221 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
R01HL155569 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
ZIAHL006001 (NIH – National Heart, Lung, and Blood Institute)
R01HL131573 (NIH – National Heart, Lung, and Blood Institute)
Publication Type:
Article
Unique ID:
10.1093/hmg/ddab240
PMID:
34415308
DOI:
10.1093/hmg/ddab240
Journal:
Human Molecular Genetics
Publication Date:
Data Source:
Web of Science
Source Link:
View Web of Science Record

Record Created:

Identification of putative causal loci in whole-genome sequencing data via knockoff statistics

He, Z., Liu, L., Wang, C., Le Guen, Y., Lee, J., Gogarten, S., Lu, F., Montgomery, S., Tang, H., Silverman, E. K., Cho, M. H., Greicius, M., & Ionita-Laza, I. (2021). Identification of putative causal loci in whole-genome sequencing data via knockoff statistics. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-22889-4
Authors:
Zihuai He
Linxi Liu
Chen Wang
Yann Le Guen
Justin Lee
Stephanie Gogarten
Fred Lu
Stephen Montgomery
Hua Tang
Edwin K. Silverman
Michael H. Cho
Michael Greicius
Iuliana Ionita-Laza
Affiliated Authors:
Linxi Liu
Chen Wang
Iuliana Ionita-Laza
Columbia Affiliation:
Grants:
U01HL096902 (NIH – National Heart, Lung, and Blood Institute)
U01HL130114 (NIH – National Heart, Lung, and Blood Institute)
U01HL096899 (NIH – National Heart, Lung, and Blood Institute)
R01HL089856 (NIH – National Heart, Lung, and Blood Institute)
U01HL089897 (NIH – National Heart, Lung, and Blood Institute)
R01HL085083 (NIH – National Heart, Lung, and Blood Institute)
U01HL096917 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
U01HL096812 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
U01HL089856 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
U01HL096814 (NIH – National Heart, Lung, and Blood Institute)
U54HG003273 (NIH – National Human Genome Research Institute)
U54HG003079 (NIH – National Human Genome Research Institute)
U54HG003067 (NIH – National Human Genome Research Institute)
R01MH106910 (NIH – National Institute of Mental Health)
R01MH095797 (NIH – National Institute of Mental Health)
R01NS017950 (NIH – National Institute of Neurological Disorders and Stroke)
U01AG049507 (NIH – National Institute On Aging)
R01AG033040 (NIH – National Institute On Aging)
U54AG052427 (NIH – National Institute On Aging)
R01AG066206 (NIH – National Institute On Aging)
R01AG054076 (NIH – National Institute On Aging)
R01AG023629 (NIH – National Institute On Aging)
U01AG052411 (NIH – National Institute On Aging)
U01AG052410 (NIH – National Institute On Aging)
U01AG016976 (NIH – National Institute On Aging)
U01AG049505 (NIH – National Institute On Aging)
U01AG052409 (NIH – National Institute On Aging)
R01AG033193 (NIH – National Institute On Aging)
U01AG049508 (NIH – National Institute On Aging)
R01AG049607 (NIH – National Institute On Aging)
U01AG049506 (NIH – National Institute On Aging)
U01AG032984 (NIH – National Institute On Aging)
U24AG021886 (NIH – National Institute On Aging)
U01AG057659 (NIH – National Institute On Aging)
UF1AG047133 (NIH – National Institute On Aging)
P30AG066515 (NIH – National Institute On Aging)
U24AG041689 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1038/s41467-021-22889-4
PMID:
34035245
DOI:
10.1038/s41467-021-22889-4
Journal:
Nature Communications
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View Web of Science Record

Record Created:

Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women

Jones, G., Trajanoska, K., Santanasto, A. J., Stringa, N., Kuo, C.-L., Atkins, J. L., Lewis, J. R., Duong, T., Hong, S., Biggs, M. L., Luan, J., Sarnowski, C., Lunetta, K. L., Tanaka, T., Wojczynski, M. K., Cvejkus, R., Nethander, M., Ghasemi, S., Yang, J., … Pilling, L. C. (2021). Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-20918-w
Authors:
Garan Jones
Katerina Trajanoska
Adam J. Santanasto
Najada Stringa
Chia-Ling Kuo
Janice L. Atkins
Joshua R. Lewis
ThuyVy Duong
Shengjun Hong
Mary L. Biggs
Jian’an Luan
Chloe Sarnowski
Kathryn L. Lunetta
Toshiko Tanaka
Mary K. Wojczynski
Ryan Cvejkus
Maria Nethander
Sahar Ghasemi
Jingyun Yang
M. Carola Zillikens
Stefan Walter
Kamil Sicinski
Erika Kague
Cheryl L. Ackert-Bicknell
Dan E. Arking
B. Gwen Windham
Eric Boerwinkle
Megan L. Grove
Misa Graff
Dominik Spira
Ilja Demuth
Nathalie van der Velde
Lisette C. P. G. M. de Groot
Bruce M. Psaty
Michelle C. Odden
Alison E. Fohner
Claudia Langenberg
Nicholas J. Wareham
Stefania Bandinelli
Natasja M. van Schoor
Martijn Huisman
Qihua Tan
Joseph Zmuda
Dan Mellström
Magnus Karlsson
David A. Bennett
Aron S. Buchman
Philip L. De Jager
Andre G. Uitterlinden
Uwe Völker
Thomas Kocher
Alexander Teumer
Leocadio Rodriguéz-Mañas
Francisco J. García
José A. Carnicero
Pamela Herd
Lars Bertram
Claes Ohlsson
Joanne M. Murabito
David Melzer
George A. Kuchel
Luigi Ferrucci
David Karasik
Fernando Rivadeneira
Douglas P. Kiel
Luke C. Pilling
Affiliated Authors:
Philip L. De Jager
Columbia Affiliation:
Subjects:
Genetic Predisposition to Disease (MeSH)
Genome-Wide Association Study (MeSH)
Muscle Weakness (MeSH)
Sarcopenia (MeSH)
Grants:
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
U01HL130114 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
K01AG057726 (NIH – National Institute On Aging)
ZIAAG000965 (NIH – National Institute On Aging)
R01AG017917 (NIH – National Institute On Aging)
ZIAAG001050 (NIH – National Institute On Aging)
R01AG015819 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1038/s41467-021-20918-w
PMID:
33510174
DOI:
10.1038/s41467-021-20918-w
Journal:
Nature Communications
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View PubMed Record
View Web of Science Record

Record Created:

A System for Phenotype Harmonization in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Program

Stilp, A. M., Emery, L. S., Broome, J. G., Buth, E. J., Khan, A. T., Laurie, C. A., Wang, F. F., Wong, Q., Chen, D., D’Augustine, C. M., Heard-Costa, N. L., Hohensee, C. R., Johnson, W. C., Juarez, L. D., Liu, J., Mutalik, K. M., Raffield, L. M., Wiggins, K. L., de Vries, P. S., … Laurie, C. C. (2021). A System for Phenotype Harmonization in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Program. American Journal of Epidemiology, 190(10), 1977–1992. https://doi.org/10.1093/aje/kwab115
Authors:
Adrienne M. Stilp
Leslie S. Emery
Jai G. Broome
Erin J. Buth
Alyna T. Khan
Cecelia A. Laurie
Fei Fei Wang
Quenna Wong
William Craig Johnson
Jan Graffelman
Wan-Ling Hsu
Cathy C. Laurie
Dongquan Chen
Ramachandran S. Vasan
Nancy L. Heard-Costa
Chancellor R. Hohensee
Jingmin Liu
Charles Kooperberg
Lucia D. Juarez
Laura M. Raffield
Kerri L. Wiggins
Joshua C. Bis
Bruce M. Psaty
Paul S. de Vries
Myriam Fornage
Alanna C. Morrison
Tanika N. Kelly
Pradeep Natarajan
Scott T. Weiss
Gina M. Peloso
L. Adrienne Cupples
Patricia A. Peyser
Lawrence F. Bielak
Sharon L. R. Kardia
Jennifer A. Smith
Alex P. Reiner
Susan R. Heckbert
Donna K. Arnett
Stella Aslibekyan
Kathleen C. Barnes
Brian E. Cade
Jiwon Lee
Cashell E. Jaquish
Catherine M. D'Augustine
Karen M. Mutalik
Ming-Huei Chen
Andrew D. Johnson
Adolfo Correa
Mariza de Andrade
Patrick T. Ellinor
Nora Franceschini
Kari E. North
Weiniu Gan
Santhi K. Ganesh
Megan L. Grove
Xiuqing Guo
Jerome Rotter
Kent D. Taylor
Nicola L. Hawley
Rebecca D. Jackson
Shannon Kelly
Rasika A. Mathias
Lisa R. Yanek
Stephen T. McGarvey
Braxton D. Mitchell
May E. Montasser
Seyed Mehdi Nouraie
Elizabeth C. Oelsner
Nathan Pankratz
Stephen S. Rich
Daniel E. Weeks
Carla G. Wilson
Affiliated Authors:
Elizabeth C. Oelsner
Columbia Affiliation:
Author Keywords:
cardiovascular disease
common data elements
hematologic disease
information dissemination
lung diseases
phenotypes
sleep-wake disorders
Grants:
UL1TR001881 (NIH – National Center for Advancing Translational Sciences)
UL1TR001420 (NIH – National Center for Advancing Translational Sciences)
UL1TR000040 (NIH – National Center for Advancing Translational Sciences)
UL1TR001079 (NIH – National Center for Advancing Translational Sciences)
KL2RR024990 (NIH – National Center for Research Resources)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
K24HL105780 (NIH – National Heart, Lung, and Blood Institute)
K01HL135405 (NIH – National Heart, Lung, and Blood Institute)
R37HL066289 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL139672 (NIH – National Heart, Lung, and Blood Institute)
R01HL122684 (NIH – National Heart, Lung, and Blood Institute)
R21HL140385 (NIH – National Heart, Lung, and Blood Institute)
R01HL085083 (NIH – National Heart, Lung, and Blood Institute)
R01HL142711 (NIH – National Heart, Lung, and Blood Institute)
U01HL089897 (NIH – National Heart, Lung, and Blood Institute)
U01HL130114 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01HL130733 (NIH – National Heart, Lung, and Blood Institute)
ZIAHL006170 (NIH – National Heart, Lung, and Blood Institute)
R03HL141439 (NIH – National Heart, Lung, and Blood Institute)
R01HL104135 (NIH – National Heart, Lung, and Blood Institute)
R01HL092577 (NIH – National Heart, Lung, and Blood Institute)
R21HL129924 (NIH – National Heart, Lung, and Blood Institute)
R01HL113338 (NIH – National Heart, Lung, and Blood Institute)
R01HL119443 (NIH – National Heart, Lung, and Blood Institute)
R01HL095163 (NIH – National Heart, Lung, and Blood Institute)
R01HL121007 (NIH – National Heart, Lung, and Blood Institute)
R01HL066216 (NIH – National Heart, Lung, and Blood Institute)
R01HL146860 (NIH – National Heart, Lung, and Blood Institute)
R01HL073410 (NIH – National Heart, Lung, and Blood Institute)
U01HL089856 (NIH – National Heart, Lung, and Blood Institute)
R01HL128914 (NIH – National Heart, Lung, and Blood Institute)
R01HL095080 (NIH – National Heart, Lung, and Blood Institute)
R01HL093093 (NIH – National Heart, Lung, and Blood Institute)
P01HL132825 (NIH – National Heart, Lung, and Blood Institute)
K23HL130627 (NIH – National Heart, Lung, and Blood Institute)
R35HL135818 (NIH – National Heart, Lung, and Blood Institute)
R44HL095169 (NIH – National Heart, Lung, and Blood Institute)
R01HL085251 (NIH – National Heart, Lung, and Blood Institute)
U01HL065233 (NIH – National Heart, Lung, and Blood Institute)
R01HL085571 (NIH – National Heart, Lung, and Blood Institute)
R01HL087660 (NIH – National Heart, Lung, and Blood Institute)
R01HL068986 (NIH – National Heart, Lung, and Blood Institute)
R43HL095161 (NIH – National Heart, Lung, and Blood Institute)
R21HL095165 (NIH – National Heart, Lung, and Blood Institute)
R43HL095169 (NIH – National Heart, Lung, and Blood Institute)
R13HL095166 (NIH – National Heart, Lung, and Blood Institute)
R43HL095160 (NIH – National Heart, Lung, and Blood Institute)
R01HL083141 (NIH – National Heart, Lung, and Blood Institute)
R43HL095167 (NIH – National Heart, Lung, and Blood Institute)
U01HG006379 (NIH – National Human Genome Research Institute)
U54HG003067 (NIH – National Human Genome Research Institute)
U01HG004735 (NIH – National Human Genome Research Institute)
R01AI132476 (NIH – National Institute of Allergy and Infectious Diseases)
R01DK117445 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30DK063491 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30ES000002 (NIH – National Institute of Environmental Health Sciences)
R01AG023629 (NIH – National Institute On Aging)
R01MD012765 (NIH – National Institute On Minority Health and Health Disparities)
Publication Type:
Article
Unique ID:
10.1093/aje/kwab115
PMID:
33861317
DOI:
10.1093/aje/kwab115
Journal:
American Journal of Epidemiology
Publication Date:
Data Source:
Web of Science
Source Link:
View Web of Science Record

Record Created:

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

de las Fuentes, L., Sung, Y. J., Noordam, R., Winkler, T., Feitosa, M. F., Schwander, K., Bentley, A. R., Brown, M. R., Guo, X., Manning, A., Chasman, D. I., Aschard, H., Bartz, T. M., Bielak, L. F., Campbell, A., Cheng, C.-Y., Dorajoo, R., Hartwig, F. P., Horimoto, A. R. V. R., … Fornage, M. (2020). Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Molecular Psychiatry, 26(6), 2111–2125. https://doi.org/10.1038/s41380-020-0719-3
Authors:
Lisa de las Fuentes
Yun Ju Sung
Raymond Noordam
Thomas Winkler
Mary F Feitosa
Karen Schwander
Amy R Bentley
Michael R Brown
Xiuqing Guo
Alisa Manning
Daniel I Chasman
Hugues Aschard
Traci M Bartz
Lawrence F Bielak
Archie Campbell
Ching-Yu Cheng
Rajkumar Dorajoo
Fernando P Hartwig
A R V R Horimoto
Changwei Li
Ruifang Li-Gao
Yongmei Liu
Jonathan Marten
Solomon K Musani
Ioanna Ntalla
Tuomo Rankinen
Melissa Richard
Xueling Sim
Albert V Smith
Salman M Tajuddin
Bamidele O Tayo
Dina Vojinovic
Helen R Warren
Deng Xuan
Maris Alver
Mathilde Boissel
Jin-Fang Chai
Xu Chen
Kaare Christensen
Jasmin Divers
Evangelos Evangelou
Chuan Gao
Giorgia Girotto
Sarah E Harris
Meian He
Fang-Chi Hsu
Brigitte Kühnel
Federica Laguzzi
Xiaoyin Li
Leo-Pekka Lyytikäinen
Ilja M Nolte
Alaitz Poveda
Rainer Rauramaa
Muhammad Riaz
Rico Rueedi
Xiao-Ou Shu
Harold Snieder
Tamar Sofer
Fumihiko Takeuchi
Niek Verweij
Erin B Ware
Stefan Weiss
Lisa R Yanek
Najaf Amin
Dan E Arking
Donna K Arnett
Sven Bergmann
Eric Boerwinkle
Jennifer A Brody
Ulrich Broeckel
Marco Brumat
Gregory Burke
Claudia P Cabrera
Mickaël Canouil
Miao Li Chee
Yii-Der Ida Chen
Massimiliano Cocca
John Connell
H Janaka de Silva
Paul S de Vries
Gudny Eiriksdottir
Jessica D Faul
Virginia Fisher
Terrence Forrester
Ervin F Fox
Yechiel Friedlander
He Gao
Bruna Gigante
Franco Giulianini
Chi Charles Gu
Dongfeng Gu
Tamara B Harris
Jiang He
Sami Heikkinen
Chew-Kiat Heng
Steven Hunt
M Arfan Ikram
Marguerite R Irvin
Mika Kähönen
Maryam Kavousi
Chiea Chuen Khor
Tuomas O Kilpeläinen
Woon-Puay Koh
Pirjo Komulainen
Aldi T Kraja
J E Krieger
Carl D Langefeld
Yize Li
Jingjing Liang
David C M Liewald
Ching-Ti Liu
Jianjun Liu
Kurt K Lohman
Reedik Mägi
Colin A McKenzie
Thomas Meitinger
Andres Metspalu
Yuri Milaneschi
Lili Milani
Dennis O Mook-Kanamori
Mike A Nalls
Christopher P Nelson
Jill M Norris
Jeff O'Connell
Adesola Ogunniyi
Sandosh Padmanabhan
Nicholette D Palmer
Nancy L Pedersen
Thomas Perls
Annette Peters
Astrid Petersmann
Patricia A Peyser
Ozren Polasek
David J Porteous
Leslie J Raffel
Treva K Rice
Jerome I Rotter
Igor Rudan
Oscar-Leonel Rueda-Ochoa
Charumathi Sabanayagam
Babatunde L Salako
Pamela J Schreiner
James M Shikany
Stephen S Sidney
Mario Sims
Colleen M Sitlani
Jennifer A Smith
John M Starr
Konstantin Strauch
Morris A Swertz
Alexander Teumer
Yih Chung Tham
André G Uitterlinden
Dhananjay Vaidya
M Yldau van der Ende
Melanie Waldenberger
Lihua Wang
Ya-Xing Wang
Wen-Bin Wei
David R Weir
Wanqing Wen
Jie Yao
Bing Yu
Caizheng Yu
Jian-Min Yuan
Wei Zhao
Alan B Zonderman
Diane M Becker
Donald W Bowden
Ian J Deary
Marcus Dörr
Tõnu Esko
Barry I Freedman
Philippe Froguel
Paolo Gasparini
Christian Gieger
Jost Bruno Jonas
Candace M Kammerer
Norihiro Kato
Timo A Lakka
Karin Leander
Terho Lehtimäki
Patrik K E Magnusson
Pedro Marques-Vidal
Brenda W J H Penninx
Nilesh J Samani
Pim van der Harst
Lynne E Wagenknecht
Tangchun Wu
Wei Zheng
Xiaofeng Zhu
Claude Bouchard
Richard S Cooper
Adolfo Correa
Michele K Evans
Vilmundur Gudnason
Caroline Hayward
Bernardo L Horta
Tanika N Kelly
Stephen B Kritchevsky
Daniel Levy
Walter R Palmas
A C Pereira
Michael M Province
Bruce M Psaty
Paul M Ridker
Charles N Rotimi
E Shyong Tai
Rob M van Dam
Cornelia M van Duijn
Tien Yin Wong
Kenneth Rice
W James Gauderman
Alanna C Morrison
Kari E North
Sharon L R Kardia
Mark J Caulfield
Paul Elliott
Patricia B Munroe
Paul W Franks
Dabeeru C Rao
Myriam Fornage
Affiliated Authors:
Walter R Palmas
Columbia Affiliation:
Subjects:
Genome-Wide Association Study (MeSH)
Hypertension (MeSH)
Grants:
K23HL105897 (NIH – National Heart Lung and Blood Institute)
K23RR016070 (NIH – National Center for Research Resources)
K25HL121091 (NIH – National Heart Lung and Blood Institute)
M01RR000052 (NIH – National Center for Research Resources)
M01RR002719 (NIH – National Center for Research Resources)
M01RR007122 (NIH – National Center for Research Resources)
M01RR010284 (NIH – National Center for Research Resources)
N01AG012100 (NIH – National Institute on Aging)
N01AG062101 (NIH – National Institute on Aging)
N01AG062103 (NIH – National Institute on Aging)
P30AG066546 (NIH – National Institute On Aging)
P30DK063491 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01AG023629 (NIH – National Institute On Aging)
R01AG032098 (NIH – National Institute On Aging)
R01CA040360 (NIH – National Cancer Institute)
R01CA047988 (NIH – National Cancer Institute)
R01CA144034 (NIH – National Cancer Institute)
R01DK071891 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK075681 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK075787 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK085175 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK089256 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK101855 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01HD042157 (NIH – Eunice Kennedy Shriver National Institute of Child Health and Human Development)
R01HG003054 (NIH – National Human Genome Research Institute)
R01HL045670 (NIH – National Heart, Lung, and Blood Institute)
R01HL053353 (NIH – National Heart, Lung, and Blood Institute)
R01HL055673 (NIH – National Heart, Lung, and Blood Institute)
R01HL059367 (NIH – National Heart, Lung, and Blood Institute)
R01HL060894 (NIH – National Heart, Lung, and Blood Institute)
R01HL060919 (NIH – National Heart Lung and Blood Institute)
R01HL060944 (NIH – National Heart, Lung, and Blood Institute)
R01HL061019 (NIH – National Heart, Lung, and Blood Institute)
R01HL064278 (NIH – National Heart Lung and Blood Institute)
R01HL065226 (NIH – National Heart Lung and Blood Institute)
R01HL065234 (NIH – National Heart Lung and Blood Institute)
R01HL067348 (NIH – National Heart Lung and Blood Institute)
R01HL071025 (NIH – National Heart Lung and Blood Institute)
R01HL071917 (NIH – National Heart Lung and Blood Institute)
R01HL074166 (NIH – National Heart Lung and Blood Institute)
R01HL080295 (NIH – National Heart, Lung, and Blood Institute)
R01HL080467 (NIH – National Heart, Lung, and Blood Institute)
R01HL085083 (NIH – National Heart, Lung, and Blood Institute)
R01HL085251 (NIH – National Heart, Lung, and Blood Institute)
R01HL086694 (NIH – National Heart, Lung, and Blood Institute)
R01HL086718 (NIH – National Heart, Lung, and Blood Institute)
R01HL087263 (NIH – National Heart, Lung, and Blood Institute)
R01HL087641 (NIH – National Heart Lung and Blood Institute)
R01HL087652 (NIH – National Heart, Lung, and Blood Institute)
R01HL087660 (NIH – National Heart, Lung, and Blood Institute)
R01HL087698 (NIH – National Heart, Lung, and Blood Institute)
R01HL090682 (NIH – National Heart, Lung, and Blood Institute)
R01HL092165 (NIH – National Heart Lung and Blood Institute)
R01HL092301 (NIH – National Heart Lung and Blood Institute)
R01HL103612 (NIH – National Heart, Lung, and Blood Institute)
R01HL105756 (NIH – National Heart, Lung, and Blood Institute)
R01HL117078 (NIH – National Heart, Lung, and Blood Institute)
R01HL118305 (NIH – National Heart, Lung, and Blood Institute)
R01HL119443 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R01LM010098 (NIH – National Library of Medicine)
R01MH081802 (NIH – National Institute of Mental Health)
R01NS017950 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS062059 (NIH – National Institute of Neurological Disorders and Stroke)
R03AG046389 (NIH – National Institute on Aging)
R13HL095166 (NIH – National Heart, Lung, and Blood Institute)
R21HL095165 (NIH – National Heart, Lung, and Blood Institute)
R37HL045508 (NIH – National Heart Lung and Blood Institute)
R43HL095160 (NIH – National Heart, Lung, and Blood Institute)
R43HL095161 (NIH – National Heart, Lung, and Blood Institute)
R43HL095167 (NIH – National Heart, Lung, and Blood Institute)
R43HL095169 (NIH – National Heart, Lung, and Blood Institute)
R44HL095169 (NIH – National Heart, Lung, and Blood Institute)
RC1HL099747 (NIH – National Heart Lung and Blood Institute)
RC2AG036495 (NIH – National Institute On Aging)
RC2MH089951 (NIH – National Institute of Mental Health)
RC2MH089995 (NIH – National Institute of Mental Health)
RC4AG039029 (NIH – National Institute On Aging)
S06GM008016 (NIH – National Institute of General Medical Sciences)
U01AG009740 (NIH – National Institute On Aging)
U01AG023746 (NIH – National Institute On Aging)
U01AG052409 (NIH – National Institute On Aging)
U01CA182876 (NIH – National Cancer Institute)
U01CA182913 (NIH – National Cancer Institute)
U01DK066134 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
U01HG004402 (NIH – National Human Genome Research Institute)
U01HG004424 (NIH – National Human Genome Research Institute)
U01HG004446 (NIH – National Human Genome Research Institute)
U01HG004729 (NIH – National Human Genome Research Institute)
U01HL054457 (NIH – National Heart Lung and Blood Institute)
U01HL054464 (NIH – National Heart Lung and Blood Institute)
U01HL054471 (NIH – National Heart Lung and Blood Institute)
U01HL054472 (NIH – National Heart Lung and Blood Institute)
U01HL054473 (NIH – National Heart Lung and Blood Institute)
U01HL054481 (NIH – National Heart Lung and Blood Institute)
U01HL054495 (NIH – National Heart Lung and Blood Institute)
U01HL054496 (NIH – National Heart Lung and Blood Institute)
U01HL054497 (NIH – National Heart Lung and Blood Institute)
U01HL054509 (NIH – National Heart Lung and Blood Institute)
U01HL065233 (NIH – National Heart, Lung, and Blood Institute)
U01HL072507 (NIH – National Heart Lung and Blood Institute)
U01HL072518 (NIH – National Heart Lung and Blood Institute)
U01HL080295 (NIH – National Heart Lung and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
U01HL130114 (NIH – National Heart, Lung, and Blood Institute)
U10HL054457 (NIH – National Heart Lung and Blood Institute)
U10HL054472 (NIH – National Heart Lung and Blood Institute)
U10HL054473 (NIH – National Heart Lung and Blood Institute)
U10HL054495 (NIH – National Heart Lung and Blood Institute)
U10HL054496 (NIH – National Heart Lung and Blood Institute)
U10HL054497 (NIH – National Heart Lung and Blood Institute)
U10HL054509 (NIH – National Heart Lung and Blood Institute)
UL1RR025005 (NIH – National Center for Research Resources)
UL1TR000040 (NIH – National Center for Advancing Translational Sciences)
UL1TR000124 (NIH – National Center for Advancing Translational Sciences)
UL1TR001079 (NIH – National Center for Advancing Translational Sciences)
UL1TR001420 (NIH – National Center for Advancing Translational Sciences)
UL1TR001881 (NIH – National Center for Advancing Translational Sciences)
UL1TR003098 (NIH – National Center for Advancing Translational Sciences)
UM1CA173640 (NIH – National Cancer Institute)
UM1CA182876 (NIH – National Cancer Institute)
UM1CA182910 (NIH – National Cancer Institute)
UM1CA182913 (NIH – National Cancer Institute)
ZIAAG000513 (NIH – National Institute On Aging)
ZIAAG000519 (NIH – National Institute on Aging)
ZIAHG200362 (NIH – National Human Genome Research Institute)
ZIAHL006001 (NIH – National Heart, Lung, and Blood Institute)
Publication Type:
Article
Unique ID:
10.1038/s41380-020-0719-3
PMID:
32372009
DOI:
10.1038/s41380-020-0719-3
Journal:
Molecular Psychiatry
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created:

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Taliun, D., Harris, D. N., Kessler, M. D., Carlson, J., Szpiech, Z. A., Torres, R., Taliun, S. A. G., Corvelo, A., Gogarten, S. M., Kang, H. M., Pitsillides, A. N., LeFaive, J., Lee, S., Tian, X., Browning, B. L., Das, S., Emde, A.-K., Clarke, W. E., Loesch, D. P., … Abecasis, G. R. (2021). Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature, 590(7845), 290–299. https://doi.org/10.1038/s41586-021-03205-y
Authors:
Daniel Taliun
Daniel N Harris
Michael D Kessler
Jedidiah Carlson
Zachary A Szpiech
Raul Torres
Sarah A Gagliano Taliun
André Corvelo
Stephanie M Gogarten
Hyun Min Kang
Achilleas N Pitsillides
Jonathon LeFaive
Seung-Been Lee
Xiaowen Tian
Brian L Browning
Sayantan Das
Anne-Katrin Emde
Wayne E Clarke
Douglas P Loesch
Amol C Shetty
Thomas W Blackwell
Albert V Smith
Quenna Wong
Xiaoming Liu
Matthew P Conomos
Dean M Bobo
François Aguet
Christine Albert
Alvaro Alonso
Kristin G Ardlie
Dan E Arking
Stella Aslibekyan
Paul L Auer
John Barnard
R Graham Barr
Lucas Barwick
Lewis C Becker
Rebecca L Beer
Emelia J Benjamin
Lawrence F Bielak
John Blangero
Michael Boehnke
Donald W Bowden
Jennifer A Brody
Esteban G Burchard
Brian E Cade
James F Casella
Brandon Chalazan
Daniel I Chasman
Yii-Der Ida Chen
Michael H Cho
Seung Hoan Choi
Mina K Chung
Clary B Clish
Adolfo Correa
Joanne E Curran
Brian Custer
Dawood Darbar
Michelle Daya
Mariza de Andrade
Dawn L DeMeo
Susan K Dutcher
Patrick T Ellinor
Leslie S Emery
Celeste Eng
Diane Fatkin
Tasha Fingerlin
Lukas Forer
Myriam Fornage
Nora Franceschini
Christian Fuchsberger
Stephanie M Fullerton
Soren Germer
Mark T Gladwin
Daniel J Gottlieb
Xiuqing Guo
Michael E Hall
Jiang He
Nancy L Heard-Costa
Susan R Heckbert
Marguerite R Irvin
Jill M Johnsen
Andrew D Johnson
Robert Kaplan
Sharon L R Kardia
Tanika Kelly
Shannon Kelly
Eimear E Kenny
Douglas P Kiel
Robert Klemmer
Barbara A Konkle
Charles Kooperberg
Anna Köttgen
Leslie A Lange
Jessica Lasky-Su
Daniel Levy
Xihong Lin
Keng-Han Lin
Chunyu Liu
Ruth J F Loos
Lori Garman
Robert Gerszten
Steven A Lubitz
Kathryn L Lunetta
Angel C Y Mak
Ani Manichaikul
Alisa K Manning
Rasika A Mathias
David D McManus
Stephen T McGarvey
James B Meigs
Deborah A Meyers
Julie L Mikulla
Mollie A Minear
Braxton D Mitchell
Sanghamitra Mohanty
May E Montasser
Courtney Montgomery
Alanna C Morrison
Joanne M Murabito
Andrea Natale
Pradeep Natarajan
Sarah C Nelson
Kari E North
Jeffrey R O'Connell
Nicholette D Palmer
Nathan Pankratz
Gina M Peloso
Patricia A Peyser
Jacob Pleiness
Wendy S Post
Bruce M Psaty
D C Rao
Susan Redline
Alexander P Reiner
Dan Roden
Jerome I Rotter
Ingo Ruczinski
Chloé Sarnowski
Sebastian Schoenherr
David A Schwartz
Jeong-Sun Seo
Sudha Seshadri
Vivien A Sheehan
Wayne H Sheu
M Benjamin Shoemaker
Nicholas L Smith
Jennifer A Smith
Nona Sotoodehnia
Adrienne M Stilp
Weihong Tang
Kent D Taylor
Marilyn Telen
Timothy A Thornton
Russell P Tracy
David J Van Den Berg
Ramachandran S Vasan
Karine A Viaud-Martinez
Scott Vrieze
Daniel E Weeks
Bruce S Weir
Scott T Weiss
Lu-Chen Weng
Cristen J Willer
Yingze Zhang
Xutong Zhao
Donna K Arnett
Allison E Ashley-Koch
Kathleen C Barnes
Eric Boerwinkle
Stacey Gabriel
Richard Gibbs
Kenneth M Rice
Stephen S Rich
Edwin K Silverman
Pankaj Qasba
Weiniu Gan
George J Papanicolaou
Deborah A Nickerson
Sharon R Browning
Michael C Zody
Sebastian Zöllner
James G Wilson
L Adrienne Cupples
Cathy C Laurie
Cashell E Jaquish
Ryan D Hernandez
Timothy D O'Connor
Gonçalo R Abecasis
Affiliated Authors:
R Graham Barr
Columbia Affiliation:
Subjects:
Genomic Studies and Association Analyses (OpenAlex Topic)
Standards and Guidelines for Genetic Variant Interpretation (OpenAlex Topic)
Regulation of RNA Processing and Function (OpenAlex Topic)
Genetic Variation (MeSH)
Genome, Human (MeSH)
Genomics (MeSH)
National Heart, Lung, and Blood Institute (U.S.) (MeSH)
Precision Medicine (MeSH)
Grants:
K24HL148521 (NIH – National Heart, Lung, and Blood Institute)
P50HL118006 (NIH – National Heart, Lung, and Blood Institute)
R01HL117626 (NIH – National Heart, Lung, and Blood Institute)
R01HL149836 (NIH – National Heart, Lung, and Blood Institute)
UG3HL151865 (NIH – National Heart, Lung, and Blood Institute)
ZIAHL006170 (NIH – National Heart, Lung, and Blood Institute)
U01HL120393 (NIH – National Heart, Lung, and Blood Institute)
R03HL154284 (NIH – National Heart, Lung, and Blood Institute)
R21HL123677 (NIH – National Heart, Lung, and Blood Institute)
ZIAHL006001 (NIH – National Heart, Lung, and Blood Institute)
R01HL131565 (NIH – National Heart, Lung, and Blood Institute)
R01HL120393 (NIH – National Heart, Lung, and Blood Institute)
K08HL141601 (NIH – National Heart, Lung, and Blood Institute)
R01HL151855 (NIH – National Heart, Lung, and Blood Institute)
K01HL135405 (NIH – National Heart, Lung, and Blood Institute)
R03HL141439 (NIH – National Heart, Lung, and Blood Institute)
R01HL142711 (NIH – National Heart, Lung, and Blood Institute)
R01HG005701 (NIH – National Human Genome Research Institute)
T32HG000040 (NIH – National Human Genome Research Institute)
R35HG010692 (NIH – National Human Genome Research Institute)
R01AI132476 (NIH – National Institute of Allergy and Infectious Diseases)
P30DK020572 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
UM1DK078616 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK117445 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30ES010126 (NIH – National Institute of Environmental Health Sciences)
K01AG059898 (NIH – National Institute On Aging)
R01DA037904 (NIH – National Institute On Drug Abuse)
R01DA044283 (NIH – National Institute On Drug Abuse)
R01MD012765 (NIH – National Institute On Minority Health and Health Disparities)
Publication Type:
Article
Unique ID:
10.1038/s41586-021-03205-y
PMID:
33568819
DOI:
10.1038/s41586-021-03205-y
Journal:
Nature
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
View Web of Science Record
View OpenAlex Record

Record Created:

CSV