Role of Homocysteine in Health and Disease

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Mallhi, A. K., Kiely, K., Roy, V., Ovchinsky, N., Woo Baidal, J. A., Rochani, H., & Zhang, J. (2025). The change of alanine aminotransferase distributions among US youths, NHANES 1988–2020. Journal of Pediatric Gastroenterology and Nutrition. Portico. https://doi.org/10.1002/jpn3.12460
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Kraal, A. Z., McFarlane, H. V., Pyne, J. D., Turney, I. C., Lao, P. J., Mazen, J., Brickman, A. M., & Manly, J. J. (2024). Does socioeconomic status modify the association between glycemic level and MRI markers of ADRD risk in middle‐aged adults? Alzheimer’s & Dementia, 20(S9). Portico. https://doi.org/10.1002/alz.094021
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Sourander, A., Silwal, S., Surcel, H.-M., Hinkka-Yli-Salomäki, S., Cheslack-Postava, K., Upadhyaya, S., McKeague, I. W., & Brown, A. S. (2025). Maternal vitamin B12 during pregnancy and schizophrenia in offspring. Psychiatry Research, 344, 116284. https://doi.org/10.1016/j.psychres.2024.116284
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VandeBunte, A. M., Lee, H., Paolillo, E. W., Hsiung, G. R., Staffaroni, A. M., Saloner, R., Tartaglia, C., Yaffe, K., Knopman, D. S., Ramos, E. M., Rascovsky, K., Bozoki, A. C., Wong, B., Domoto‐Reilly, K., Snyder, A., Pressman, P., Mendez, M. F., Litvan, I., … Fields, J. A. (2024). Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14172
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Chen, Q., Aguirre, L., Liang, G., Zhao, H., Dong, T., Borrego, F., de Rojas, I., Hu, Q., Reyes, C., Su, L.-Y., Zhang, B., Lechleiter, J. D., Göring, H. H. H., De Jager, P. L., Kleinman, J. E., Hyde, T. M., Li, P. P., Ruiz, A., Weinberger, D. R., … Ma, L. (2024). Identification of a specific APOE transcript and functional elements associated with Alzheimer’s disease. Molecular Neurodegeneration, 19(1). https://doi.org/10.1186/s13024-024-00751-7
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Carter, R. C. (2024). The critical need for novel precision medicine methodologies in fetal alcohol spectrum disorders. The American Journal of Clinical Nutrition, 119(1), 5–6. https://doi.org/10.1016/j.ajcnut.2023.10.027
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Yang, H., Mukherjee, S., Latimer, C. S., Teng, L., White, C. C., Yu, L., Sperling, R. A., Larson, E. B., Crane, P. K., Keene, C. D., Bennett, D. A. A., Schneider, J. A., & De Jager, P. L. (2023). A genome‐wide association study of LATE‐NC (limbic‐predominant age‐related TDP‐43 encephalopathy neuropathologic change) reveals a distinct genetic architecture. Alzheimer’s & Dementia, 19(S12). Portico. https://doi.org/10.1002/alz.079393
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Mann, J. J., Hur, K., Lavigne, J. E., & Gibbons, R. D. (2023). Folic acid prescription and suicide attempt prevention: effect of past suicidal behaviour, psychiatric diagnosis and psychotropic medication. BJPsych Open, 9(5). https://doi.org/10.1192/bjo.2023.549
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Martinez-Calle, M., Courbon, G., Hunt-Tobey, B., Francis, C., Spindler, J., Wang, X., dos Reis, L. M., Martins, C. S. W., Salusky, I. B., Malluche, H., Nickolas, T. L., Moyses, R. M. A., Martin, A., & David, V. (2023). Transcription factor HNF4α2 promotes osteogenesis and prevents bone abnormalities in mice with renal osteodystrophy. Journal of Clinical Investigation, 133(11). https://doi.org/10.1172/jci159928
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Monfrini, E., Pesini, A., Biella, F., Sobreira, C. F. R., Emmanuele, V., Brescia, G., Lopez, L. C., Tadesse, S., Hirano, M., Comi, G. P., Quinzii, C. M., & Di Fonzo, A. (2023). Whole-Exome Sequencing Study of Fibroblasts Derived From Patients With Cerebellar Ataxia Referred to Investigate CoQ10 Deficiency. Neurology Genetics, 9(2). https://doi.org/10.1212/nxg.0000000000200058
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Zhu, J., Chen, C., Lu, L., Shikany, J. M., D’Alton, M. E., & Kahe, K. (2023). Folate, Vitamin B6, and Vitamin B12Status in Association With Metabolic Syndrome Incidence. JAMA Network Open, 6(1), e2250621. https://doi.org/10.1001/jamanetworkopen.2022.50621
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Caspa Gokulan, R., Paulrasu, K., Azfar, J., El-Rifai, W., Que, J., Boutaud, O. G., Ban, Y., Gao, Z., Buitrago, M. G., Dikalov, S. I., & Zaika, A. I. (2023). Protein adduction causes non-mutational inhibition of p53 tumor suppressor. Cell Reports, 42(1), 112024. https://doi.org/10.1016/j.celrep.2023.112024
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Moore, A., Busch, M. P., Dziewulska, K., Francis, R. O., Hod, E. A., Zimring, J. C., D’Alessandro, A., & Page, G. P. (2022). Genome-wide metabolite quantitative trait loci analysis (mQTL) in red blood cells from volunteer blood donors. Journal of Biological Chemistry, 298(12), 102706. https://doi.org/10.1016/j.jbc.2022.102706
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Oussalah, A., Siblini, Y., Hergalant, S., Chéry, C., Rouyer, P., Cavicchi, C., Guerrini, R., Morange, P.-E., Trégouët, D., Pupavac, M., Watkins, D., Pastinen, T., Chung, W. K., Ficicioglu, C., Feillet, F., Froese, D. S., Baumgartner, M. R., Benoist, J.-F., Majewski, J., … Guéant, J.-L. (2022). Epimutations in both the TESK2 and MMACHC promoters in the Epi-cblC inherited disorder of intracellular metabolism of vitamin B12. Clinical Epigenetics, 14(1). https://doi.org/10.1186/s13148-022-01271-1
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Tahir, U. A., Katz, D. H., Avila-Pachecho, J., Bick, A. G., Pampana, A., Robbins, J. M., Yu, Z., Chen, Z.-Z., Benson, M. D., Cruz, D. E., Ngo, D., Deng, S., Shi, X., Zheng, S., Eisman, A. S., Farrell, L., Hall, M. E., Correa, A., Tracy, R. P., … Gerszten, R. E. (2022). Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32275-3
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Subbanna, S., & Basavarajappa, B. S. (2022). Binge-like Prenatal Ethanol Exposure Causes Impaired Cellular Differentiation in the Embryonic Forebrain and Synaptic and Behavioral Defects in Adult Mice. Brain Sciences, 12(6), 793. https://doi.org/10.3390/brainsci12060793
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Ullal, J., Kutney, K., Williams, K. M., & Weber, D. R. (2022). Treatment of cystic fibrosis related bone disease. Journal of Clinical & Translational Endocrinology, 27, 100291. https://doi.org/10.1016/j.jcte.2021.100291
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Paolino, J. D., Flamand, Y., Stevenson, K. E., Koch, V., Athale, U. H., Cole, P. D., Gennarini, L. M., Kahn, J. M., Kelly, K. M., Laverdiere, C., Leclerc, J.-M., Michon, B., Place, A. E., Supko, J. G., Tran, T. H., Welch, J. J. G., Neuberg, D. S., Sallan, S. E., Silverman, L. B., & Vrooman, L. M. (2021). Impact of Age, Body Surface Area, and Body Mass Index on Pegaspargase Toxicity and Pharmacokinetics: A Report from the DFCI ALL Consortium. Blood, 138(Supplement 1), 3396–3396. https://doi.org/10.1182/blood-2021-151313
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Walters, M. C., Tisdale, J. F., Mapara, M. Y., Krishnamurti, L., Kwiatkowski, J. L., Aygun, B., Kasow, K. A., Rifkin-Zenenberg, S., Jaroscak, J., Garbinsky, D., Chirila, C., Gallagher, M. E., Zhang, X., Ho, P.-R., Thompson, A. A., & Kanter, J. (2021). Sustained Improvements in Patient-Reported Quality of Life up to 24 Months Post-Treatment with LentiGlobin for Sickle Cell Disease (bb1111) Gene Therapy. Blood, 138(Supplement 1), 7–7. https://doi.org/10.1182/blood-2021-146905
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Towheed, A., Hietanen, C. L., Kamath, V. G., Singh, L. N., Ho, A., Engelstad, K., Cornett, K., Montes, J., & De Vivo, D. (2021). Hypotonia–cystinuria 2p21 deletion syndrome: Intrafamilial variability of clinical expression. Annals of Clinical and Translational Neurology, 8(11), 2199–2204. Portico. https://doi.org/10.1002/acn3.51464
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