Lindman, B. R., Pibarot, P., Schwartz, A., Oldemeyer, J. B., Su, Y. R., Goel, K., Cohen, D. J., Fearon, W. F., Babaliaros, V., Daniels, D., Chhatriwalla, A., Suradi, H. S., Shah, P., Szerlip, M., Mack, M. J., Dahle, T., O’Neill, W. W., Davidson, C. J., Makkar, R., … Généreux, P. (2025). Cardiac Biomarkers in Patients with Asymptomatic Severe Aortic Stenosis: Analysis from the EARLY TAVR Trial. Circulation. https://doi.org/10.1161/circulationaha.125.074425

Stehlik, J., Farr, M. A., Mehra, M. R., Schroder, J. N., D’Alessandro, D. A., Pal, J. D., Villavicencio, M. A., Gruber, P. J., Couper, G. S., Shudo, Y., Patel, P. C., Daneshmand, M. A., Klein, L., Shah, A. S., Skipper, E. R., Esmailian, F., Goldstein, D., Ohira, S., Lozonschi, L., … Milano, C. A. (2025). Clinical Outcomes With Normothermic Pulsatile Organ Perfusion in Heart Transplantation: A Report From the OCS Heart Perfusion Registry. Circulation, 151(13), 896–909. https://doi.org/10.1161/circulationaha.124.071743

Martin, S. S., Aday, A. W., Allen, N. B., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., Baker-Smith, C. M., Bansal, N., Beaton, A. Z., Commodore-Mensah, Y., Currie, M. E., Elkind, M. S. V., Fan, W., Generoso, G., Gibbs, B. B., Heard, D. G., Hiremath, S., … Johansen, M. C. (2025). 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association. Circulation, 151(8). https://doi.org/10.1161/cir.0000000000001303

Hall, E. J., Agarwal, S., Cullum, C. M., Sinha, S. S., Ely, E. W., & Farr, M. A. (2025). Survivorship After Cardiogenic Shock. Circulation, 151(3), 257–271. https://doi.org/10.1161/circulationaha.124.068203

Rosenthal, E., Qureshi, S. A., Sivakumar, K., Jones, M., Yong, S.-F., Kabir, S., Sagar, P., Thejaswi, P., Hascoet, S., Batteux, C., Boudjemline, Y., Hijazi, Z. M., Aboulhosn, J. A., Levi, D. S., Salem, M. M., Francis, E., Kempny, A., Fraisse, A., Bautista-Rodriguez, C., … Zahn, E. M. (2024). Covered Stent Correction for Sinus Venosus Atrial Septal Defects, an Emerging Alternative to Surgical Repair: Results of an International Registry. Circulation. https://doi.org/10.1161/circulationaha.124.070271

Liu, J., Bellows, B. K., Jacobs, D. R., Woo, J. G., Urbina, E. M., Balte, P. P., Oelsner, E. C., Kazi, D. S., Siscovick, D., Allen, N. B., Rana, J. S., Wilkins, J. T., Hall, M. E., Bazzano, L. A., Burns, T. L., Daniels, S. R., Dwyer, T., Juonala, M., Raitakari, O. T., … Zhang, Y. (2024). Low-Density Lipoprotein Cholesterol Level Distributions Across Different Ages: Implications for Screening Children for Severe and Familial Hypercholesterolemia. Circulation, 150(21), 1741–1744. https://doi.org/10.1161/circulationaha.124.069792

Judge, D. P., Gillmore, J. D., Alexander, K. M., Ambardekar, A. V., Cappelli, F., Fontana, M., García-Pavía, P., Grodin, J. L., Grogan, M., Hanna, M., Masri, A., Nativi-Nicolau, J., Obici, L., Hvitfeldt Poulsen, S., Sarswat, N., Shah, K., Soman, P., Lystig, T., Cao, X., … Maurer, M. S. (2024). Long-Term Efficacy and Safety of Acoramidis in ATTR-CM: Initial Report From the Open-Label Extension of the ATTRibute-CM Trial. Circulation. https://doi.org/10.1161/circulationaha.124.072771

Vukadinović, D., Lauder, L., Kandzari, D. E., Bhatt, D. L., Kirtane, A. J., Edelman, E. R., Schmieder, R. E., Azizi, M., Böhm, M., & Mahfoud, F. (2024). Effects of Catheter-Based Renal Denervation in Hypertension: A Systematic Review and Meta-Analysis. Circulation, 150(20), 1599–1611. https://doi.org/10.1161/circulationaha.124.069709

Liou, L., Maurer, M. S., & Kontorovich, A. R. (2024). Improved Access to Genetics Care is Needed to Address Health Inequities in ATTRv Amyloidosis. Circulation, 150(14), 1072–1074. https://doi.org/10.1161/circulationaha.124.070525

Shaddy, R., Burch, M., Kantor, P. F., Solar-Yohay, S., Garito, T., Zhang, S., Kocun, M., Mao, C., Cilliers, A., Wang, X., Canter, C., Rossano, J., Wallis, G., Menteer, J., Daou, L., Kusa, J., Tokel, K., Dilber, D., Xu, Z., … Zuhlke, L. (2024). Sacubitril/Valsartan in Pediatric Heart Failure (PANORAMA-HF): A Randomized, Multicenter, Double-Blind Trial. Circulation, 150(22), 1756–1766. https://doi.org/10.1161/circulationaha.123.066605

Martinez-Morata, I., Schilling, K., Glabonjat, R. A., Domingo-Relloso, A., Mayer, M., McGraw, K. E., Galvez Fernandez, M., Sanchez, T. R., Nigra, A. E., Kaufman, J. D., Vaidya, D., Jones, M. R., Bancks, M. P., Barr, R. G., Shimbo, D., Post, W. S., Valeri, L., Shea, S., & Navas-Acien, A. (2024). Association of Urinary Metals With Cardiovascular Disease Incidence and All-Cause Mortality in the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation, 150(10), 758–769. https://doi.org/10.1161/circulationaha.124.069414

Li, J., Sun, S., Zhu, D., Mei, X., Lyu, Y., Huang, K., Li, Y., Liu, S., Wang, Z., Hu, S., Lutz, H. J., Popowski, K. D., Dinh, P.-U. C., Butte, A. J., & Cheng, K. (2024). Inhalable Stem Cell Exosomes Promote Heart Repair After Myocardial Infarction. Circulation, 150(9), 710–723. https://doi.org/10.1161/circulationaha.123.065005

Goel, K., Makkar, R., Krishnaswamy, A., Kapadia, S., Kodali, S., Shah, A., Barker, C., Xu, K., Dhoble, A., Yadav, P., Rihal, C. S., Abbas, A. E., Guerrero, M., & Whisenant, B. (2024). Contemporary Outcomes and Trends for the Transseptal Mitral Valve-in-Valve Procedure Using Balloon Expandable Transcatheter Valves in the United States. Circulation. https://doi.org/10.1161/circulationaha.124.068847

Moran, A. E., & Goldman, L. (2024). Predicting the Future Prevalence of Cardiovascular Disease: The Good, the Bad, the Known, and the Unknown. Circulation, 150(4), 253–254. https://doi.org/10.1161/circulationaha.124.070265

Long, A., Haggerty, C. M., Finer, J., Hartzel, D., Jing, L., Keivani, A., Kelsey, C., Rocha, D., Ruhl, J., vanMaanen, D., Metser, G., Duffy, E., Mawson, T., Maurer, M., Einstein, A. J., Beecy, A., Kumaraiah, D., Homma, S., Liu, Q., … Poterucha, T. J. (2024). Deep Learning for Echo Analysis, Tracking, and Evaluation of Mitral Regurgitation (DELINEATE-MR). Circulation. https://doi.org/10.1161/circulationaha.124.068996

Dar, K. B., & Ali, S. R. (2024). Seeing is Believing: Muscleblind-like 1 Is Necessary For Mammalian Cardiomyocyte Maturation. Circulation, 149(23), 1830–1832. https://doi.org/10.1161/circulationaha.124.068657

Katchman, A. N., Zakharov, S. I., Bohnen, M. S., Sanchez Jimenez, A., Kushner, J. S., Yang, L., Chen, B., Nasari, A., Liu, G., Rabbani, D. E., Han, J., Leu, C.-S., Pitt, G. S., & Marx, S. O. (2024). Augmented Cardiac Inotropy by Phosphodiesterase Inhibition Requires Phosphorylation of Rad and Increased Calcium Current. Circulation, 149(20), 1617–1620. https://doi.org/10.1161/circulationaha.123.067298

Rubin, L. J. (2024). Is There a Role for Calcium Channel Blockers in the Contemporary Treatment Paradigm for Pulmonary Arterial Hypertension? Circulation, 149(20), 1565–1567. https://doi.org/10.1161/circulationaha.124.069124

Elkind, M. S. V. (2024). Stroke Science and Care Since the Founding of the American Heart Association. Circulation, 149(19), 1469–1470. https://doi.org/10.1161/circulationaha.123.065471

Pan, H., Ho, S. E., Xue, C., Cui, J., Johanson, Q. S., Sachs, N., Ross, L. S., Li, F., Solomon, R. A., Connolly, E. S., Patel, V. I., Maegdefessel, L., Zhang, H., & Reilly, M. P. (2024). Atherosclerosis Is a Smooth Muscle Cell–Driven Tumor-Like Disease. Circulation, 149(24), 1885–1898. https://doi.org/10.1161/circulationaha.123.067587

Bashore, A. C., Chung, A., Ibikunle, C., Yan, H., Xue, C., Li, M., Bauer, R. C., & Reilly, M. P. (2024). Single-Cell Multimodal Profiling of Atherosclerosis Identifies CD200 as a Cell Surface Lineage Marker of Vascular Smooth Muscle Cells and Their Derived Cells. Circulation, 149(15), 1231–1233. https://doi.org/10.1161/circulationaha.123.067092

Reiffel, J. A. (2024). Atrial Fibrillation: Why Are We Hiding Reality? Circulation, 149(13), 979–980. https://doi.org/10.1161/circulationaha.123.067544

Kapadia, S. R., Krishnaswamy, A., Whisenant, B., Potluri, S., Iyer, V., Aragon, J., Gideon, P., Strote, J., Leonardi, R., Agarwal, H., Larrain, G., Sanchez, C., Panaich, S. S., Harvey, J., Vahl, T., Menon, V., Wolski, K., Wang, Q., & Leon, M. B. (2024). Concomitant Left Atrial Appendage Occlusion and Transcatheter Aortic Valve Replacement Among Patients With Atrial Fibrillation. Circulation, 149(10), 734–743. https://doi.org/10.1161/circulationaha.123.067312

Martin, S. S., Aday, A. W., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., Baker-Smith, C. M., Barone Gibbs, B., Beaton, A. Z., Boehme, A. K., Commodore-Mensah, Y., Currie, M. E., Elkind, M. S. V., Evenson, K. R., Generoso, G., Heard, D. G., Hiremath, S., Johansen, M. C., … Kalani, R. (2024). 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association. Circulation, 149(8). https://doi.org/10.1161/cir.0000000000001209

Bacha, E., & Farr, M. (2024). The Future of Pediatric and Adult Heart Transplantation: Perspective From the United States. Circulation, 149(5), 339–341. https://doi.org/10.1161/circulationaha.123.065450

Sidik, N. P., Stanley, B., Sykes, R., Morrow, A. J., Bradley, C. P., McDermott, M., Ford, T. J., Roditi, G., Hargreaves, A., Stobo, D., Adams, J., Byrne, J., Mahrous, A., Young, R., Carrick, D., McGeoch, R., Corcoran, D., Lang, N. N., Heggie, R., … Berry, C. (2024). Invasive Endotyping in Patients With Angina and No Obstructive Coronary Artery Disease: A Randomized Controlled Trial. Circulation, 149(1), 7–23. https://doi.org/10.1161/circulationaha.123.064751

Yalcinkaya, M., Liu, W., Thomas, L.-A., Olszewska, M., Xiao, T., Abramowicz, S., Papapetrou, E. P., Westerterp, M., Wang, N., Tabas, I., & Tall, A. R. (2023). BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis. Circulation, 148(22), 1764–1777. https://doi.org/10.1161/circulationaha.123.065344

Azizi, M., Sharp, A. S. P., Fisher, N. D. L., Weber, M. A., Lobo, M. D., Daemen, J., Lurz, P., Mahfoud, F., Schmieder, R. E., Basile, J., Bloch, M. J., Saxena, M., Wang, Y., Sanghvi, K., Jenkins, J. S., Devireddy, C., Rader, F., Gosse, P., Claude, L., … Renkin, J. (2024). Patient-Level Pooled Analysis of Endovascular Ultrasound Renal Denervation or a Sham Procedure 6 Months After Medication Escalation: The RADIANCE Clinical Trial Program. Circulation, 149(10), 747–759. https://doi.org/10.1161/circulationaha.123.066941

Goldberg, C. S., Trachtenberg, F., William Gaynor, J., Mahle, W. T., Ravishankar, C., Schwartz, S. M., Cnota, J. F., Ohye, R. G., Gongwer, R., Taylor, M., Paridon, S., Frommelt, P. C., Afton, K., Atz, A. M., Burns, K. M., Detterich, J. A., Hill, K. D., Cabrera, A. G., … Lewis, A. B. (2023). Longitudinal Follow-Up of Children With HLHS and Association Between Norwood Shunt Type and Long-Term Outcomes: The SVR III Study. Circulation, 148(17), 1330–1339. https://doi.org/10.1161/circulationaha.123.065192

Cochran, J. D., Yura, Y., Thel, M. C., Doviak, H., Polizio, A. H., Arai, Y., Arai, Y., Horitani, K., Park, E., Chavkin, N. W., Kour, A., Sano, S., Mahajan, N., Evans, M., Huba, M., Naya, N. M., Sun, H., Ban, Y. H., Hirschi, K. K., … Walsh, K. (2023). Clonal Hematopoiesis in Clinical and Experimental Heart Failure With Preserved Ejection Fraction. Circulation, 148(15), 1165–1178. https://doi.org/10.1161/circulationaha.123.064170

Javanmardi, E., Ehlert, F., & Yarmohammadi, H. (2023). A Curious Presentation of Chronic Chest Pain. Circulation, 148(7), 610–612. https://doi.org/10.1161/circulationaha.123.065372

Filipkowski, A. M., Kundu, S., Eden, S. K., Alcorn, C. W., Justice, A. C., So-Armah, K. A., Tindle, H. A., Wells, Q. S., Beckman, J. A., Freiberg, M. S., & Aday, A. W. (2023). Association of HIV Infection and Incident Abdominal Aortic Aneurysm Among 143 001 Veterans. Circulation, 148(2), 135–143. https://doi.org/10.1161/circulationaha.122.063040

Galper, B. Z., Chinnakondepalli, K. M., Wang, K., Magnuson, E. A., Lu, M., Thourani, V. H., Kodali, S., Makkar, R., Herrmann, H. C., Kapadia, S., Williams, M., Webb, J., Smith, C. R., Mack, M. J., Leon, M. B., & Cohen, D. J. (2023). Economic Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Severe Aortic Stenosis and Low Surgical Risk: Results from the PARTNER 3 Trial. Circulation, 147(21), 1594–1605. https://doi.org/10.1161/circulationaha.122.062481

Conway, J., Min, S., Villa, C., Weintraub, R. G., Nakano, S., Godown, J., Tatangelo, M., Armstrong, K., Richmond, M., Kaufman, B., Lal, A. K., Balaji, S., Power, A., Baez Hernandez, N., Gardin, L., Kantor, P. F., Parent, J. J., Aziz, P. F., Jefferies, J. L., … Mital, S. (2023). The Prevalence and Association of Exercise Test Abnormalities With Sudden Cardiac Death and Transplant-Free Survival in Childhood Hypertrophic Cardiomyopathy. Circulation, 147(9), 718–727. https://doi.org/10.1161/circulationaha.122.062699

Gyldenkerne, C., Maeng, M., Kjøller-Hansen, L., Maehara, A., Zhou, Z., Ben-Yehuda, O., Erik Bøtker, H., Engstrøm, T., Matsumura, M., Mintz, G. S., Fröbert, O., Persson, J., Wiseth, R., Larsen, A. I., Jensen, L. O., Nordrehaug, J. E., Bleie, Ø., Omerovic, E., Held, C., … Erlinge, D. (2023). Coronary Artery Lesion Lipid Content and Plaque Burden in Diabetic and Nondiabetic Patients: PROSPECT II. Circulation, 147(6), 469–481. https://doi.org/10.1161/circulationaha.122.061983

Paluch, A. E., Bajpai, S., Ballin, M., Bassett, D. R., Buford, T. W., Carnethon, M. R., Chernofsky, A., Dooley, E. E., Ekelund, U., Evenson, K. R., Galuska, D. A., Jefferis, B. J., Kong, L., Kraus, W. E., Larson, M. G., Lee, I.-M., Matthews, C. E., Newton, R. L., … Nordström, A. (2023). Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis. Circulation, 147(2), 122–131. https://doi.org/10.1161/circulationaha.122.061288

Hahn, R. T., Chan, V., & Adams, D. H. (2022). Current Indications for Transcatheter Edge-to-Edge Repair in a Patient With Primary Mitral Regurgitation. Circulation, 146(17), 1263–1265. https://doi.org/10.1161/circulationaha.122.061495

Garry, D. J., Weiner, J. I., Greising, S. M., Garry, M. G., & Sachs, D. H. (2022). Cardiac Xenotransplantation: Clinical Impact of Science and Discovery. Circulation, 146(13), 961–963. https://doi.org/10.1161/circulationaha.122.059191

Post, W. S., Watson, K. E., Hansen, S., Folsom, A. R., Szklo, M., Shea, S., Barr, R. G., Burke, G., Bertoni, A. G., Allen, N., Pankow, J. S., Lima, J. A. C., Rotter, J. I., Kaufman, J. D., Johnson, W. C., Kronmal, R. A., Diez-Roux, A. V., & McClelland, R. L. (2022). Racial and Ethnic Differences in All-Cause and Cardiovascular Disease Mortality: The MESA Study. Circulation, 146(3), 229–239. https://doi.org/10.1161/circulationaha.122.059174

Shishehbor, M. H., Zeller, T., Werner, M., Brodmann, M., Parise, H., Holden, A., Lichtenberg, M., Parikh, S. A., Kashyap, V. S., Pietras, C., Tirziu, D., Ardakani, S., Beschorner, U., Krishnan, P., Niazi, K. A., Wali, A. U., & Lansky, A. J. (2022). Randomized Trial of Chocolate Touch Compared With Lutonix Drug-Coated Balloon in Femoropopliteal Lesions (Chocolate Touch Study). Circulation, 145(22), 1645–1654. https://doi.org/10.1161/circulationaha.122.059646

Kohli-Lynch, C. N., Lewsey, J., Boyd, K. A., French, D. D., Jordan, N., Moran, A. E., Sattar, N., Preiss, D., & Briggs, A. H. (2022). Beyond 10-Year Risk: A Cost-Effectiveness Analysis of Statins for the Primary Prevention of Cardiovascular Disease. Circulation, 145(17), 1312–1323. https://doi.org/10.1161/circulationaha.121.057631

Rahman, S., Biviano, A., & Yarmohammadi, H. (2022). Fast and Furious: A Case of Group Beating and Cardiomyopathy. Circulation, 145(17), 1364–1366. https://doi.org/10.1161/circulationaha.122.059656

Riaz, M., Park, J., Sewanan, L. R., Ren, Y., Schwan, J., Das, S. K., Pomianowski, P. T., Huang, Y., Ellis, M. W., Luo, J., Liu, J., Song, L., Chen, I.-P., Qiu, C., Yazawa, M., Tellides, G., Hwa, J., Young, L. H., Yang, L., … Qyang, Y. (2022). Muscle LIM Protein Force-Sensing Mediates Sarcomeric Biomechanical Signaling in Human Familial Hypertrophic Cardiomyopathy. Circulation, 145(16), 1238–1253. https://doi.org/10.1161/circulationaha.121.056265

Glazer, A. M., Davogustto, G., Shaffer, C. M., Vanoye, C. G., Desai, R. R., Farber-Eger, E. H., Dikilitas, O., Shang, N., Pacheco, J. A., Yang, T., Muhammad, A., Mosley, J. D., Van Driest, S. L., Wells, Q. S., Shaffer, L. L., Kalash, O. R., Wada, Y., Bland, H. T., Yoneda, Z. T., … Roden, D. M. (2022). Arrhythmia Variant Associations and Reclassifications in the eMERGE-III Sequencing Study. Circulation, 145(12), 877–891. https://doi.org/10.1161/circulationaha.121.055562

Kandzari, D. E., Mahfoud, F., Weber, M. A., Townsend, R., Parati, G., Fisher, N. D. L., Lobo, M. D., Bloch, M., Böhm, M., Sharp, A. S. P., Schmieder, R. E., Azizi, M., Schlaich, M. P., Papademetriou, V., Kirtane, A. J., Daemen, J., Pathak, A., Ukena, C., Lurz, P., … Spitzer, E. (2022). Clinical Trial Design Principles and Outcomes Definitions for Device-Based Therapies for Hypertension: A Consensus Document From the Hypertension Academic Research Consortium. Circulation, 145(11), 847–863. https://doi.org/10.1161/circulationaha.121.057687

Truong, D. T., Dionne, A., Muniz, J. C., McHugh, K. E., Portman, M. A., Lambert, L. M., Thacker, D., Elias, M. D., Li, J. S., Toro-Salazar, O. H., Anderson, B. R., Atz, A. M., Bohun, C. M., Campbell, M. J., Chrisant, M., D’Addese, L., Dummer, K. B., Forsha, D., Frank, L. H., … Newburger, J. W. (2022). Clinically Suspected Myocarditis Temporally Related to COVID-19 Vaccination in Adolescents and Young Adults: Suspected Myocarditis After COVID-19 Vaccination. Circulation, 145(5), 345–356. https://doi.org/10.1161/circulationaha.121.056583

Knops, R. E., van der Stuijt, W., Delnoy, P. P. H. M., Boersma, L. V. A., Kuschyk, J., El-Chami, M. F., Bonnemeier, H., Behr, E. R., Brouwer, T. F., Kääb, S., Mittal, S., Quast, A.-F. B. E., Smeding, L., Tijssen, J. G. P., Bijsterveld, N. R., Richter, S., Brouwer, M. A., de Groot, J. R., Kooiman, K. M., … Wright, D. J. (2022). Efficacy and Safety of Appropriate Shocks and Antitachycardia Pacing in Transvenous and Subcutaneous Implantable Defibrillators: Analysis of All Appropriate Therapy in the PRAETORIAN Trial. Circulation, 145(5), 321–329. https://doi.org/10.1161/circulationaha.121.057816

Al Rifai, M., Blaha, M. J., Nambi, V., Shea, S. J. C., Michos, E. D., Blumenthal, R. S., Ballantyne, C. M., Szklo, M., Greenland, P., Miedema, M. D., Nasir, K., Rotter, J. I., Guo, X., Yao, J., Post, W. S., & Virani, S. S. (2022). Determinants of Incident Atherosclerotic Cardiovascular Disease Events Among Those With Absent Coronary Artery Calcium: Multi-Ethnic Study of Atherosclerosis. Circulation, 145(4), 259–267. https://doi.org/10.1161/circulationaha.121.056705

Lawton, J. S., Tamis-Holland, J. E., Bangalore, S., Bates, E. R., Beckie, T. M., Bischoff, J. M., Bittl, J. A., Cohen, M. G., DiMaio, J. M., Don, C. W., Fremes, S. E., Gaudino, M. F., Goldberger, Z. D., Grant, M. C., Jaswal, J. B., Kurlansky, P. A., Mehran, R., Metkus, T. S., Nnacheta, L. C., … Zwischenberger, B. A. (2022). 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation, 145(3). https://doi.org/10.1161/cir.0000000000001038

Batra, J., Biviano, A., & Yarmohammadi, H. (2022). Dancing Bundles With Stable Sinus Rhythm. Circulation, 145(1), 84–86. https://doi.org/10.1161/circulationaha.121.058218