Human Genetics and Genomics Advances

Displaying 1 - 14 of 14
Young, R. E., Zuccaro, M. V., LeDuc, C. A., Germain, N. D., Kim, T. H., Sarmiere, P., & Chung, W. K. (2025). Pathogenic PPP2R5D variants disrupt neuronal development and neurite outgrowth in patient-derived neurons that are reversed by allele-specific knockdown. Human Genetics and Genomics Advances, 6(3), 100450. https://doi.org/10.1016/j.xhgg.2025.100450
Publication Date
Tang, S., Liu, S., Buchman, A. S., Bennett, D. A., De Jager, P. L., Yang, J., & Hu, J. (2025). Integrating spatial transcriptomics and snRNA-seq data enhances differential gene expression analysis results of AD-related phenotypes. Human Genetics and Genomics Advances, 6(3), 100447. https://doi.org/10.1016/j.xhgg.2025.100447
Publication Date
Darko, M. E., Kappy, M., Rabizadeh, D., Jalas, C., Forman, E. J., Brady, P., & Williams, Z. (2025). A Variant in RNF212B May Contribute to Female Infertility and Recurrent Pregnancy Loss. Human Genetics and Genomics Advances, 100443. https://doi.org/10.1016/j.xhgg.2025.100443
Publication Date
Yalcouyé, A., Schrauwen, I., Traoré, O., Bamba, S., Aboagye, E. T., Acharya, A., Bharadwaj, T., Latanich, R., Esoh, K., Fortes-Lima, C. A., de Kock, C., Jonas, M., Maiga, A. dit B., Cissé, C. A. K., Sangaré, M. A., Guinto, C. O., Landouré, G., Leal, S. M., & Wonkam, A. (2025). Whole-exome sequencing reveals known and candidate genes for hearing impairment in Mali. Human Genetics and Genomics Advances, 6(1), 100391. https://doi.org/10.1016/j.xhgg.2024.100391
Publication Date
Jungels, A., Demers, L., Ford, E., Stevens, B. K., Sabatello, M., & Dasgupta, S. (2023). Project Inclusive Genetics: Protecting reproductive autonomy from bias via prenatal patient-centered counseling. Human Genetics and Genomics Advances, 4(4), 100228. https://doi.org/10.1016/j.xhgg.2023.100228
Publication Date
Corradi, Z., Khan, M., Hitti-Malin, R., Mishra, K., Whelan, L., Cornelis, S. S., Hoyng, C. B., Kämpjärvi, K., Klaver, C. C. W., Liskova, P., Stöhr, H., Weber, B. H. F., Banfi, S., Farrar, G. J., Sharon, D., Zernant, J., Allikmets, R., Dhaenens, C.-M., & Cremers, F. P. M. (2023). Targeted sequencing and in vitro splice assays shed light on ABCA4-associated retinopathies missing heritability. Human Genetics and Genomics Advances, 4(4), 100237. https://doi.org/10.1016/j.xhgg.2023.100237
Publication Date
Bentz, M., Saperstein, A., Fullerton, S. M., Shim, J. K., & Lee, S. S.-J. (2024). Conflating race and ancestry: Tracing decision points about population descriptors over the precision medicine research life course. Human Genetics and Genomics Advances, 5(1), 100243. https://doi.org/10.1016/j.xhgg.2023.100243
Publication Date
Padgett, L. R., Shinkle, M. R., Rosario, S., Stewart, T. M., Foley, J. R., Casero, R. A., Park, M. H., Chung, W. K., & Mastracci, T. L. (2023). Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis. Human Genetics and Genomics Advances, 4(3), 100206. https://doi.org/10.1016/j.xhgg.2023.100206
Publication Date
Young, K. L., Fisher, V., Deng, X., Brody, J. A., Graff, M., Lim, E., Lin, B. M., Xu, H., Amin, N., An, P., Aslibekyan, S., Fohner, A. E., Hidalgo, B., Lenzini, P., Kraaij, R., Medina-Gomez, C., Prokić, I., Rivadeneira, F., Sitlani, C., … Liu, C.-T. (2023). Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants. Human Genetics and Genomics Advances, 4(1), 100163. https://doi.org/10.1016/j.xhgg.2022.100163
Publication Date
Chen, J., Wang, L., De Jager, P. L., Bennett, D. A., Buchman, A. S., & Yang, J. (2022). A scalable Bayesian functional GWAS method accounting for multivariate quantitative functional annotations with applications for studying Alzheimer disease. Human Genetics and Genomics Advances, 3(4), 100143. https://doi.org/10.1016/j.xhgg.2022.100143
Publication Date
Zhong, G., Ahimaz, P., Edwards, N. A., Hagen, J. J., Faure, C., Lu, Q., Kingma, P., Middlesworth, W., Khlevner, J., El Fiky, M., Schindel, D., Fialkowski, E., Kashyap, A., Forlenza, S., Kenny, A. P., Zorn, A. M., Shen, Y., & Chung, W. K. (2022). Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas. Human Genetics and Genomics Advances, 3(3), 100107. https://doi.org/10.1016/j.xhgg.2022.100107
Publication Date
Zhang, C., Jolly, A., Shayota, B. J., Mazzeu, J. F., Du, H., Dawood, M., Soper, P. C., Ramalho de Lima, A., Ferreira, B. M., Coban-Akdemir, Z., White, J., Shears, D., Thomson, F. R., Douglas, S. L., Wainwright, A., Bailey, K., Wordsworth, P., Oldridge, M., Lester, T., … Carvalho, C. M. B. (2022). Novel pathogenic variants and quantitative phenotypic analyses of Robinow syndrome: WNT signaling perturbation and phenotypic variability. Human Genetics and Genomics Advances, 3(1), 100074. https://doi.org/10.1016/j.xhgg.2021.100074
Publication Date
Sun, D., Richard, M. A., Musani, S. K., Sung, Y. J., Winkler, T. W., Schwander, K., Chai, J. F., Guo, X., Kilpeläinen, T. O., Vojinovic, D., Aschard, H., Bartz, T. M., Bielak, L. F., Brown, M. R., Chitrala, K., Hartwig, F. P., Horimoto, A. R. V. R., Liu, Y., Manning, A. K., … Fornage, M. (2021). Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits. Human Genetics and Genomics Advances, 2(1), 100013. https://doi.org/10.1016/j.xhgg.2020.100013
Publication Date