Human Genetics and Genomics Advances
Displaying 1 - 14 of 14
Young, R. E., Zuccaro, M. V., LeDuc, C. A., Germain, N. D., Kim, T. H., Sarmiere, P., & Chung, W. K. (2025). Pathogenic PPP2R5D variants disrupt neuronal development and neurite outgrowth in patient-derived neurons that are reversed by allele-specific knockdown. Human Genetics and Genomics Advances, 6(3), 100450. https://doi.org/10.1016/j.xhgg.2025.100450
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Columbia Affiliation
Tang, S., Liu, S., Buchman, A. S., Bennett, D. A., De Jager, P. L., Yang, J., & Hu, J. (2025). Integrating spatial transcriptomics and snRNA-seq data enhances differential gene expression analysis results of AD-related phenotypes. Human Genetics and Genomics Advances, 6(3), 100447. https://doi.org/10.1016/j.xhgg.2025.100447
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Darko, M. E., Kappy, M., Rabizadeh, D., Jalas, C., Forman, E. J., Brady, P., & Williams, Z. (2025). A Variant in RNF212B May Contribute to Female Infertility and Recurrent Pregnancy Loss. Human Genetics and Genomics Advances, 100443. https://doi.org/10.1016/j.xhgg.2025.100443
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Columbia Affiliation
Yalcouyé, A., Schrauwen, I., Traoré, O., Bamba, S., Aboagye, E. T., Acharya, A., Bharadwaj, T., Latanich, R., Esoh, K., Fortes-Lima, C. A., de Kock, C., Jonas, M., Maiga, A. dit B., Cissé, C. A. K., Sangaré, M. A., Guinto, C. O., Landouré, G., Leal, S. M., & Wonkam, A. (2025). Whole-exome sequencing reveals known and candidate genes for hearing impairment in Mali. Human Genetics and Genomics Advances, 6(1), 100391. https://doi.org/10.1016/j.xhgg.2024.100391
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Columbia Affiliation
Sabatello, M., Bakken, S., Chung, W. K., Cohn, E., Crew, K. D., Kiryluk, K., Kukafka, R., Weng, C., & Appelbaum, P. S. (2024). Return of polygenic risk scores in research: Stakeholders’ views on the eMERGE-IV study. Human Genetics and Genomics Advances, 5(2), 100281. https://doi.org/10.1016/j.xhgg.2024.100281
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Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Medicine; Division of Nephrology; Division of Hematology/Oncology; Department of Epidemiology; Department of Biomedical Informatics; Department of Sociomedical Sciences; Mailman School of Public Health; Department of Psychiatry; Center for Law, Ethics, and Psychiatry; Center for Precision Medicine and Genomics; Division of Ethics; Department of Medical Humanities and Ethics; School of Nursing
Jungels, A., Demers, L., Ford, E., Stevens, B. K., Sabatello, M., & Dasgupta, S. (2023). Project Inclusive Genetics: Protecting reproductive autonomy from bias via prenatal patient-centered counseling. Human Genetics and Genomics Advances, 4(4), 100228. https://doi.org/10.1016/j.xhgg.2023.100228
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Corradi, Z., Khan, M., Hitti-Malin, R., Mishra, K., Whelan, L., Cornelis, S. S., Hoyng, C. B., Kämpjärvi, K., Klaver, C. C. W., Liskova, P., Stöhr, H., Weber, B. H. F., Banfi, S., Farrar, G. J., Sharon, D., Zernant, J., Allikmets, R., Dhaenens, C.-M., & Cremers, F. P. M. (2023). Targeted sequencing and in vitro splice assays shed light on ABCA4-associated retinopathies missing heritability. Human Genetics and Genomics Advances, 4(4), 100237. https://doi.org/10.1016/j.xhgg.2023.100237
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Columbia Affiliation
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Bentz, M., Saperstein, A., Fullerton, S. M., Shim, J. K., & Lee, S. S.-J. (2024). Conflating race and ancestry: Tracing decision points about population descriptors over the precision medicine research life course. Human Genetics and Genomics Advances, 5(1), 100243. https://doi.org/10.1016/j.xhgg.2023.100243
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Padgett, L. R., Shinkle, M. R., Rosario, S., Stewart, T. M., Foley, J. R., Casero, R. A., Park, M. H., Chung, W. K., & Mastracci, T. L. (2023). Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis. Human Genetics and Genomics Advances, 4(3), 100206. https://doi.org/10.1016/j.xhgg.2023.100206
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Young, K. L., Fisher, V., Deng, X., Brody, J. A., Graff, M., Lim, E., Lin, B. M., Xu, H., Amin, N., An, P., Aslibekyan, S., Fohner, A. E., Hidalgo, B., Lenzini, P., Kraaij, R., Medina-Gomez, C., Prokić, I., Rivadeneira, F., Sitlani, C., … Liu, C.-T. (2023). Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants. Human Genetics and Genomics Advances, 4(1), 100163. https://doi.org/10.1016/j.xhgg.2022.100163
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Columbia Affiliation
Chen, J., Wang, L., De Jager, P. L., Bennett, D. A., Buchman, A. S., & Yang, J. (2022). A scalable Bayesian functional GWAS method accounting for multivariate quantitative functional annotations with applications for studying Alzheimer disease. Human Genetics and Genomics Advances, 3(4), 100143. https://doi.org/10.1016/j.xhgg.2022.100143
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Zhong, G., Ahimaz, P., Edwards, N. A., Hagen, J. J., Faure, C., Lu, Q., Kingma, P., Middlesworth, W., Khlevner, J., El Fiky, M., Schindel, D., Fialkowski, E., Kashyap, A., Forlenza, S., Kenny, A. P., Zorn, A. M., Shen, Y., & Chung, W. K. (2022). Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas. Human Genetics and Genomics Advances, 3(3), 100107. https://doi.org/10.1016/j.xhgg.2022.100107
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Zhang, C., Jolly, A., Shayota, B. J., Mazzeu, J. F., Du, H., Dawood, M., Soper, P. C., Ramalho de Lima, A., Ferreira, B. M., Coban-Akdemir, Z., White, J., Shears, D., Thomson, F. R., Douglas, S. L., Wainwright, A., Bailey, K., Wordsworth, P., Oldridge, M., Lester, T., … Carvalho, C. M. B. (2022). Novel pathogenic variants and quantitative phenotypic analyses of Robinow syndrome: WNT signaling perturbation and phenotypic variability. Human Genetics and Genomics Advances, 3(1), 100074. https://doi.org/10.1016/j.xhgg.2021.100074
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Sun, D., Richard, M. A., Musani, S. K., Sung, Y. J., Winkler, T. W., Schwander, K., Chai, J. F., Guo, X., Kilpeläinen, T. O., Vojinovic, D., Aschard, H., Bartz, T. M., Bielak, L. F., Brown, M. R., Chitrala, K., Hartwig, F. P., Horimoto, A. R. V. R., Liu, Y., Manning, A. K., … Fornage, M. (2021). Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits. Human Genetics and Genomics Advances, 2(1), 100013. https://doi.org/10.1016/j.xhgg.2020.100013
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