Chahine, L. M., Lafontant, D.-E., Choi, S. H., Iwaki, H., Blauwendraat, C., Singleton, A. B., Brumm, M. C., Alcalay, R. N., Merchant, K., Nudelman, K. N. H., Dagher, A., Vo, A., Tao, Q., Venuto, C. S., Kieburtz, K., Poston, K. L., Bressman, S., Gonzalez-Latapi, P., Avants, B., … Tolosa, E. (2025). LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization. Brain Communications, 7(2). https://doi.org/10.1093/braincomms/fcaf103

Goldstein, O., Shani, S., Gana-Weisz, M., Elkoshi, N., Casey, F., Sun, Y. H., Chandratre, K., Cedarbaum, J. M., Blauwendraat, C., Bar-Shira, A., Thaler, A., Gurevich, T., Mirelman, A., Giladi, N., Orr-Urtreger, A., & Alcalay, R. N. (2025). The effect of polygenic risk score on PD risk and phenotype in LRRK2 G2019S and GBA1 carriers. Journal of Parkinson’s Disease. https://doi.org/10.1177/1877718x241310722

Lee, I., Mitsumoto, H., Lee, S., Kasarskis, E., Rosenbaum, M., Factor‐Litvak, P., & Nieves, J. W. (2025). Interaction between riluzole treatment and dietary glycemic index in the disease progression of amyotrophic lateral sclerosis. Annals of Clinical and Translational Neurology. Portico. https://doi.org/10.1002/acn3.52294

Williams, G. P., Freuchet, A., Michaelis, T., Frazier, A., Tran, N. K., Rodrigues Lima-Junior, J., Phillips, E. J., Mallal, S. A., Litvan, I., Goldman, J. G., Alcalay, R. N., Sidney, J., Sulzer, D., Sette, A., & Lindestam Arlehamn, C. S. (2024). PINK1 is a target of T cell responses in Parkinson’s disease. Journal of Clinical Investigation. https://doi.org/10.1172/jci180478

Jones-Tabah, J., He, K., Karpilovsky, N., Senkevich, K., Deyab, G., Pietrantonio, I., Goiran, T., Cousineau, Y., Nikanorova, D., Goldsmith, T., del Cid Pellitero, E., Chen, C. X.-Q., Luo, W., You, Z., Abdian, N., Ahmad, J., Ruskey, J. A., Asayesh, F., Spiegelman, D., … Fon, E. A. (2024). The Parkinson’s disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons. Molecular Neurodegeneration, 19(1). https://doi.org/10.1186/s13024-024-00779-9

Aivalioti, E., Georgiopoulos, G., Tual-Chalot, S., Bampatsias, D., Delialis, D., Sopova, K., Drakos, S. G., Stellos, K., & Stamatelopoulos, K. (2024). Amyloid-beta metabolism in age-related neurocardiovascular diseases. European Heart Journal. https://doi.org/10.1093/eurheartj/ehae655

Lettenberger, S. E., Hartman, E. A., Tam, K., Auinger, P., Pawlik, M. E., Wilson, R., Banda, E. T., Valdovinos, B., Kinel, D., Alcalay, R. N., Dorsey, E. R., Norcliffe-Kaufmann, L., Sharma, S., Holloway, R. G., & Schneider, R. B. (2024). Return of individual research results to participants with and at risk for Parkinson’s disease. Journal of Clinical and Translational Science, 8(1). https://doi.org/10.1017/cts.2024.616

Shiner, T., Kavé, G., Mirelman, A., Regev, K., Piura, Y., Goldstein, O., Gana Weisz, M., Bar‐Shira, A., Gurevich, T., Orr‐Urtreger, A., Alcalay, R. N., Giladi, N., & Bregman, N. (2024). Effect of GBA1 Mutations and APOE Polymorphisms on Survival and Progression Among Ashkenazi Jews with Dementia with Lewy Bodies. Movement Disorders. Portico. https://doi.org/10.1002/mds.30003

Kumar, A., Matulis, K. L., Fadel, Z. A., Fanning, A. S., Amlang, C. J., & Kuo, S.-H. (2024). Effects of Low-Frequency Deep Brain Stimulation in Bilateral Zona Incerta for a Patient With Tremor and Cerebellar Ataxia. Tremor and Other Hyperkinetic Movements, 14, 42. https://doi.org/10.5334/tohm.925

Cook, L., Verbrugge, J., Schwantes-An, T.-H., Schulze, J., Foroud, T., Hall, A., Marder, K. S., Mata, I. F., Mencacci, N. E., Nance, M. A., Schwarzschild, M. A., Simuni, T., Bressman, S., Wills, A.-M., Fernandez, H. H., Litvan, I., Lyons, K. E., Shill, H. A., Singer, C., … Alcalay, R. N. (2024). Parkinson’s disease variant detection and disclosure: PD GENEration, a North American study. Brain, 147(8), 2668–2679. https://doi.org/10.1093/brain/awae142

Fu, C., Yang, N., Chuang, J.-Z., Nakajima, N., Iraha, S., Roy, N., Wu, Z., Jiang, Z., Otsu, W., Radu, R. A., Yang, H. H., Lee, M. P., Worgall, T. S., Xiong, W.-C., & Sung, C.-H. (2024). Mutant mice with rod-specific VPS35 deletion exhibit retinal α-synuclein pathology-associated degeneration. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-50189-0

LoPiccolo, M. K., Wang, Z., Eshed, G. M., Fierro, L., Stauffer, C., Wang, K., Zhang, J., Tatsuoka, C., Balwani, M., Zou, W., & Alcalay, R. N. (2024). Skin α‐Synuclein Seeding Activity in Patients with Type 1 Gaucher Disease. Movement Disorders. Portico. https://doi.org/10.1002/mds.29935

Smilowska, K., Mehanna, R., Fleisher, J. E., Alcalay, R. N., Kumar, K. R., Marras, C., Oosterbaan, A. M., Post, B., Ross, O. A., Pimentel Piemonte, M. E., Fraix, V., Moro, E., King Tan, E., & Savica, R. (2024). Unmet Need in Early-Onset Parkinson’s Disease: Deep Brain Stimulation and Pregnancy. Journal of Parkinson’s Disease, 1–6. https://doi.org/10.3233/jpd-240088

Chia, R., Ray, A., Shah, Z., Ding, J., Ruffo, P., Fujita, M., Menon, V., Saez-Atienzar, S., Reho, P., Kaivola, K., Walton, R. L., Reynolds, R. H., Karra, R., Sait, S., Akcimen, F., Diez-Fairen, M., Alvarez, I., Fanciulli, A., Stefanova, N., … Scholz, S. W. (2024). Genome sequence analyses identify novel risk loci for multiple system atrophy. Neuron, 112(13), 2142-2156.e5. https://doi.org/10.1016/j.neuron.2024.04.002

Barbuti, P. A. (2024). A-Syn(ful) MAM: A Fresh Perspective on a Converging Domain in Parkinson’s Disease. International Journal of Molecular Sciences, 25(12), 6525. https://doi.org/10.3390/ijms25126525

Kumbier, K., Roth, M., Li, Z., Lazzari-Dean, J., Waters, C., Hammerlindl, S., Rinaldi, C., Huang, P., Korobeynikov, V. A., Phatnani, H., Shneider, N., Jacobson, M. P., Wu, L. F., & Altschuler, S. J. (2024). Identifying FUS amyotrophic lateral sclerosis disease signatures in patient dermal fibroblasts. Developmental Cell. https://doi.org/10.1016/j.devcel.2024.05.011

Wang, H.-P., Scalco, R., Saito, N., Beckett, L., Nguyen, M.-L., Huie, E. Z., Honig, L. S., DeCarli, C., Rissman, R. A., Teich, A. F., Mungas, D. M., Jin, L.-W., & Dugger, B. N. (2024). The neuropathological landscape of small vessel disease and Lewy pathology in a cohort of Hispanic and non-Hispanic White decedents with Alzheimer disease. Acta Neuropathologica Communications, 12(1). https://doi.org/10.1186/s40478-024-01773-4

Eisen, A., Vucic, S., & Mitsumoto, H. (2024). History of ALS and the competing theories on pathogenesis: IFCN handbook chapter. Clinical Neurophysiology Practice, 9, 1–12. https://doi.org/10.1016/j.cnp.2023.11.004

Heisler, J. M., Toledo-Atucha, J., Lin, C.-C., Patel, H. N., & Ondo, W. G. (2024). Orthostatic hypotension and subjective symptomatic orthostasis in Parkinson’s disease: Associations and correlations. Clinical Parkinsonism & Related Disorders, 11, 100262. https://doi.org/10.1016/j.prdoa.2024.100262

Shani, S., Gana-Weisz, M., Bar-Shira, A., Thaler, A., Gurevich, T., Mirelman, A., Giladi, N., Alcalay, R. N., Goldstein, O., & Orr-Urtreger, A. (2023). MAPT Locus in Parkinson’s Disease Patients of Ashkenazi Origin: A Stratified Analysis. Genes, 15(1), 46. https://doi.org/10.3390/genes15010046

Middleton, J., MacLeod, K. R., Bozoki, A., Galvin, J. E., Irwin, D. J., Lippa, C., Litvan, I., Lopez, O. L., Berman, S., Tsuang, D. W., Zabetian, C. P., Honig, L. S., Marder, K., Fleisher, J. E., Sabbagh, M., Wint, D., Taylor, A., Bekris, L. M., Leverenz, J. B., & Galasko, D. R. (2023). Use of α‐synuclein seed amplification assays to assess how clinical features relate to the diagnosis of Dementia with Lewy Bodies. Alzheimer’s & Dementia, 19(S14). Portico. https://doi.org/10.1002/alz.078103

Mitsumoto, H., Cheung, K., Oskarsson, B., Andrews, H. F., Jang, G. E., Andrews, J. A., Shah, J. S., Fernandes, J. A., McElhiney, M., & Santella, R. M. (2023). Randomized double-blind personalized N-of-1 clinical trial to test the safety and potential efficacy of TJ-68 for treating muscle cramps in amyotrophic lateral sclerosis (ALS): study protocol for a TJ-68 trial. Trials, 24(1). https://doi.org/10.1186/s13063-023-07424-8

Lee, I., Mitsumoto, H., Lee, S., Kasarskis, E., Rosenbaum, M., Factor‐Litvak, P., & Nieves, J. W. (2023). Higher Glycemic Index and Glycemic Load Diet Is Associated with Slower Disease Progression in Amyotrophic Lateral Sclerosis. Annals of Neurology, 95(2), 217–229. Portico. https://doi.org/10.1002/ana.26825

Ré, D. B., & Rideout, H. J. (2023). Why the Gut Microbiome Must Be Considered When Evaluating the Impact of Pesticides on Parkinson’s Disease Risk. Journal of Parkinson’s Disease, 13(7), 1077–1078. https://doi.org/10.3233/jpd-239004

Garretti, F., Monahan, C., Sloan, N., Bergen, J., Shahriar, S., Kim, S. W., Sette, A., Cutforth, T., Kanter, E., Agalliu, D., & Sulzer, D. (2023). Interaction of an α-synuclein epitope with HLA-DRB1∗15:01 triggers enteric features in mice reminiscent of prodromal Parkinson’s disease. Neuron, 111(21), 3397-3413.e5. https://doi.org/10.1016/j.neuron.2023.07.015

Rekova, P., Dostalova, G., Rob, D., Vaneckova, M., Pavlicova, M., Linhart, A., & Kemlink, D. (2023). Cerebrovascular Phenotype in Fabry Disease Patients Assessed by Ultrasound. Journal of Ultrasound in Medicine, 42(10), 2315–2330. Portico. https://doi.org/10.1002/jum.16254

Qi, R., Sammler, E., Gonzalez-Hunt, C. P., Barraza, I., Pena, N., Rouanet, J. P., Naaldijk, Y., Goodson, S., Fuzzati, M., Blandini, F., Erickson, K. I., Weinstein, A. M., Lutz, M. W., Kwok, J. B., Halliday, G. M., Dzamko, N., Padmanabhan, S., Alcalay, R. N., Waters, C., … Sanders, L. H. (2023). A blood-based marker of mitochondrial DNA damage in Parkinson’s disease. Science Translational Medicine, 15(711). https://doi.org/10.1126/scitranslmed.abo1557

Pal, G., Cook, L., Schulze, J., Verbrugge, J., Alcalay, R. N., Merello, M., Sue, C. M., Bardien, S., Bonifati, V., Chung, S. J., Foroud, T., Gatto, E., Hall, A., Hattori, N., Lynch, T., Marder, K., Mascalzoni, D., Novaković, I., Thaler, A., … Klein, C. (2023). Genetic Testing in Parkinson’s Disease. Movement Disorders, 38(8), 1384–1396. Portico. https://doi.org/10.1002/mds.29500

Blauwendraat, C., Tayebi, N., Woo, E. G., Lopez, G., Fierro, L., Toffoli, M., Limbachiya, N., Hughes, D., Pitz, V., Patel, D., Vitale, D., Koretsky, M. J., Hernandez, D., Real, R., Alcalay, R. N., Nalls, M. A., Morris, H. R., Schapira, A. H. V., Balwani, M., & Sidransky, E. (2023). Polygenic Parkinson’s Disease Genetic Risk Score as Risk Modifier of Parkinsonism in Gaucher Disease. Movement Disorders, 38(5), 899–903. Portico. https://doi.org/10.1002/mds.29342

Hauser, R. A., LeWitt, P. A., Waters, C. H., Grosset, D. G., & Blank, B. (2023). The Clinical Development of Levodopa Inhalation Powder. Clinical Neuropharmacology, 46(2), 66–78. https://doi.org/10.1097/wnf.0000000000000540

Vöglein, J., Franzmeier, N., Morris, J. C., Dieterich, M., McDade, E., Simons, M., Preische, O., Hofmann, A., Hassenstab, J., Benzinger, T. L., Fagan, A., Noble, J. M., Berman, S. B., Graff‐Radford, N. R., Ghetti, B., Farlow, M. R., Chhatwal, J. P., Salloway, S., … Xiong, C. (2022). Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease. Alzheimer’s & Dementia, 19(2), 632–645. Portico. https://doi.org/10.1002/alz.12684

Williams, G. P., Muskat, K., Frazier, A., Xu, Y., Mateus, J., Grifoni, A., da Silva Antunes, R., Weiskopf, D., Amara, A. W., Standaert, D. G., Goldman, J. G., Litvan, I., Alcalay, R. N., Sulzer, D., Lindestam Arlehamn, C. S., & Sette, A. (2023). Unaltered T cell responses to common antigens in individuals with Parkinson’s disease. Journal of the Neurological Sciences, 444, 120510. https://doi.org/10.1016/j.jns.2022.120510

Lin, C. R., Amokrane, N., Chen, S., Chen, T. X., Lai, R., Trinh, P., Minyetty, M. J., Emmerich, H., Pan, M., Claassen, D. O., & Kuo, S. (2022). Cerebellar impulsivity–compulsivity assessment scale. Annals of Clinical and Translational Neurology, 10(1), 48–57. Portico. https://doi.org/10.1002/acn3.51698

Kedariti, M., Frattini, E., Baden, P., Cogo, S., Civiero, L., Ziviani, E., Zilio, G., Bertoli, F., Aureli, M., Kaganovich, A., Cookson, M. R., Stefanis, L., Surface, M., Deleidi, M., Di Fonzo, A., Alcalay, R. N., Rideout, H., Greggio, E., & Plotegher, N. (2022). LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson’s disease. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00354-3

Avisar, H., Guardia-Laguarta, C., Surface, M., Papagiannakis, N., Maniati, M., Antonellou, R., Papadimitriou, D., Koros, C., Athanassiadou, A., Przedborski, S., Lerner, B., Stefanis, L., Area-Gomez, E., & Alcalay, R. N. (2022). Lipid level alteration in human and cellular models of alpha synuclein mutations. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00313-y

Dhanwani, R., Lima-Junior, J. R., Sethi, A., Pham, J., Williams, G., Frazier, A., Xu, Y., Amara, A. W., Standaert, D. G., Goldman, J. G., Litvan, I., Alcalay, R. N., Peters, B., Sulzer, D., Arlehamn, C. S. L., & Sette, A. (2022). Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00282-2

Hopfner, F., Tietz, A. K., Ruf, V. C., Ross, O. A., Koga, S., Dickson, D., Aguzzi, A., Attems, J., Beach, T., Beller, A., Cheshire, W. P., van Deerlin, V., Desplats, P., Deuschl, G., Duyckaerts, C., Ellinghaus, D., Evsyukov, V., Flanagan, M. E., Franke, A., … Höglinger, G. (2022). Common Variants Near ZIC1 and ZIC4 in Autopsy‐Confirmed Multiple System Atrophy. Movement Disorders, 37(10), 2110–2121. Portico. https://doi.org/10.1002/mds.29164

Dvir, D., Unbehaun, A., Kodali, S., Tchetche, D., Pibarot, P., Leipsic, J., Blanke, P., Gerckens, U., Manoharan, G., Kempfert, J., Abdel-Wahab, M., Klein, C., Leon, M., Harari, E., Hellou, E., Wolak, A., Ben-Assa, E., Ju’beh, R., Shoby, M., & Koifman, E. (2022). TCT-506 First Dedicated Leaflet Splitting Device for Prevention of Coronary Obstruction in Transcatheter Aortic Valve Replacement: From Bench Evaluation to First-in-Human Procedures. Journal of the American College of Cardiology, 80(12), B206. https://doi.org/10.1016/j.jacc.2022.08.597

Crotty, G. F., Keavney, J. L., Alcalay, R. N., Marek, K., Marshall, G. A., Rosas, H. D., & Schwarzschild, M. A. (2022). Planning for Prevention of Parkinson Disease. Neurology, 99(7_Supplement_1), 1–9. https://doi.org/10.1212/wnl.0000000000200789

Hallacli, E., Kayatekin, C., Nazeen, S., Wang, X. H., Sheinkopf, Z., Sathyakumar, S., Sarkar, S., Jiang, X., Dong, X., Di Maio, R., Wang, W., Keeney, M. T., Felsky, D., Sandoe, J., Vahdatshoar, A., Udeshi, N. D., Mani, D. R., Carr, S. A., Lindquist, S., … Khurana, V. (2022). The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability. Cell, 185(12), 2035-2056.e33. https://doi.org/10.1016/j.cell.2022.05.008

Du, W., Bain, P. G., Defazio, G., Jankovic, J., Kim, C. Y., Tan, E. K., Vidailhet, M., & Louis, E. D. (2022). The Conundrum of Dystonia in Essential Tremor Patients: How does One Classify these Cases? Tremor and Other Hyperkinetic Movements, 12(1). https://doi.org/10.5334/tohm.690

Chang, A., Xiang, X., Wang, J., Lee, C., Arakhamia, T., Simjanoska, M., Wang, C., Carlomagno, Y., Zhang, G., Dhingra, S., Thierry, M., Perneel, J., Heeman, B., Forgrave, L. M., DeTure, M., DeMarco, M. L., Cook, C. N., Rademakers, R., Dickson, D. W., … Fitzpatrick, A. W. P. (2022). Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185(8), 1346-1355.e15. https://doi.org/10.1016/j.cell.2022.02.026

Dong, C., Honrao, C., Rodrigues, L. O., Wolf, J., Sheehan, K. B., Surface, M., Alcalay, R. N., & O’Day, E. M. (2022). Plasma Metabolite Signature Classifies Male LRRK2 Parkinson’s Disease Patients. Metabolites, 12(2), 149. https://doi.org/10.3390/metabo12020149

Peterschmitt, M. J., Saiki, H., Hatano, T., Gasser, T., Isaacson, S. H., Gaemers, S. J. M., Minini, P., Saubadu, S., Sharma, J., Walbillic, S., Alcalay, R. N., Cutter, G., Hattori, N., Höglinger, G. U., Marek, K., Schapira, A. H. V., Scherzer, C. R., Simuni, T., … Fischer, T. Z. (2022). Safety, Pharmacokinetics, and Pharmacodynamics of Oral Venglustat in Patients with Parkinson’s Disease and a GBA Mutation: Results from Part 1 of the Randomized, Double-Blinded, Placebo-Controlled MOVES-PD Trial. Journal of Parkinson’s Disease, 12(2), 557–570. https://doi.org/10.3233/jpd-212714