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Borot, F., Humbert, O., Ehmsen, J. T., Fields, E., Kohli, S., Radtke, S., Swing, K., Pande, D., Enstrom, M. R., Laszlo, G. S., Mayuranathan, T., Ali, A. M., Weiss, M. J., Yen, J. S., Newby, G. A., Walter, R. B., Liu, D. R., Mukherjee, S., & Kiem, H.-P. (2025). Multiplex base editing to protect from CD33 directed drugs for immune and gene therapy. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-59713-2

Müller-Dott, S., Jaehnig, E. J., Munchic, K. P., Jiang, W., Yaron-Barir, T. M., Savage, S. R., Garrido-Rodriguez, M., Johnson, J. L., Lussana, A., Petsalaki, E., Lei, J. T., Dugourd, A., Krug, K., Cantley, L. C., Mani, D. R., Zhang, B., & Saez-Rodriguez, J. (2025). Comprehensive evaluation of phosphoproteomic-based kinase activity inference. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-59779-y

Carmona, L. M., Nelson, A., Tun, L. T., Kim, A., Shiao, R., Kissner, M. D., Menon, V., & Costa, R. M. (2025). Corticothalamic neurons in motor cortex have a permissive role in motor execution. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-59954-1

Zhao, Y., Lan, T., Zhong, G., Hagen, J., Pan, H., Chung, W. K., & Shen, Y. (2025). A probabilistic graphical model for estimating selection coefficients of nonsynonymous variants from human population sequence data. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-59937-2

Thakur, B., Katte, R. H., Xu, W., Janowska, K., Sammour, S., Henderson, R., Lu, M., Kwong, P. D., & Acharya, P. (2025). Conformational trajectory of the HIV-1 fusion peptide during CD4-induced envelope opening. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-59721-2

Lansky, S., Wang, Z., Clarke, O. B., Chipot, C., & Scheuring, S. (2025). Structural dynamics and permeability of the TRPV3 pentamer. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-59798-9

Zanni, G., van Dijk, M. T., Cagliostro, M. C., Sepulveda, P., Pini, N., Rose, A. L., Kesin, A. L., Lugo-Candelas, C., Goncalves, P. D., MacKay, A. S., Iigaya, K., Kulkarni, P., Ferris, C. F., Weissman, M. M., Talati, A., Ansorge, M. S., & Gingrich, J. A. (2025). Perinatal SSRI exposure impacts innate fear circuit activation and behavior in mice and humans. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58785-4

Gao, V., Chlebowicz, J., Gaskin, K., Briano, J. A., Komer, L. E., Pineda, A., Jhalani, S., Ahmad, S., Uwaifo, E., Black, L. S., Haller, J. E., Przedborski, S., Lane, D. A., Zhang, S., Sharma, M., & Burré, J. (2025). Synaptic vesicle-omics in mice captures signatures of aging and synucleinopathy. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-59441-7

Liu, Y., Brown, C. M., Borges, N., Nobre, R. N., Erramilli, S., Belcher Dufrisne, M., Kloss, B., Giacometti, S., Esteves, A. M., Timóteo, C. G., Tokarz, P., Cater, R. J., Lowary, T. L., Morita, Y. S., Kossiakoff, A. A., Santos, H., Stansfeld, P. J., Nygaard, R., & Mancia, F. (2025). Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57843-1

Liu, Y., Brown, C. M., Erramilli, S., Su, Y.-C., Guu, S.-Y., Tseng, P.-S., Wang, Y.-J., Duong, N. H., Tokarz, P., Kloss, B., Han, C.-R., Chen, H.-Y., Rodrigues, J., Khoo, K.-H., Archer, M., Kossiakoff, A. A., Lowary, T. L., Stansfeld, P. J., Nygaard, R., & Mancia, F. (2025). Structural insights into terminal arabinosylation of mycobacterial cell wall arabinan. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58196-5

Pottier, C., Küçükali, F., Baker, M., Batzler, A., Jenkins, G. D., van Blitterswijk, M., Vicente, C. T., De Coster, W., Wynants, S., Van de Walle, P., Ross, O. A., Murray, M. E., Faura, J., Haggarty, S. J., van Rooij, J. GJ., Mol, M. O., Hsiung, G.-Y. R., Graff, C., Öijerstedt, L., … Rademakers, R. (2025). Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-59216-0

Ford, C., de Sena-Tomás, C., Wun, T. T. R., Aleman, A. G., Rangaswamy, U., Leyhr, J., Nuñez, M. I., Gao, C. Z., Nim, H. T., See, M., Coppola, U., Waxman, J. S., Ramialison, M., Haitina, T., Smeeton, J., Sanges, R., & Targoff, K. L. (2025). Nkx2.7 is a conserved regulator of craniofacial development. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58821-3

Shirley, S., Ichise, H., Di Natale, V., Jin, J., Wu, C., Zou, R., Zhang, W., Fang, Y., Zhang, Y., Chen, M., Peng, S., Basu, U., Que, J., & Huang, Y. (2025). A vasculature-resident innate lymphoid cell population in mouse lungs. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58982-1

Nakamura, K., Aoyama-Ishiwatari, S., Nagao, T., Paaran, M., Obara, C. J., Sakurai-Saito, Y., Johnston, J., Du, Y., Suga, S., Tsuboi, M., Nakakido, M., Tsumoto, K., Kishi, Y., Gotoh, Y., Kwak, C., Rhee, H.-W., Seo, J. K., Kosako, H., Potter, C., … Hirabayashi, Y. (2025). Mitochondrial complexity is regulated at ER-mitochondria contact sites via PDZD8-FKBP8 tethering. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58538-3

Jayaraman, S., Kochiss, A., Alcalay, T.-L., del Rivero Morfin, P. J., & Ben-Johny, M. (2025). Engineered depalmitoylases enable selective manipulation of protein localization and function. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58908-x

Acosta Ingram, D., Turkes, E., Kim, T. Y., Vo, S., Sweeney, N., Bonte, M.-A., Rutherford, R., Julian, D. L., Pan, M., Marsh, J., Argouarch, A. R., Wu, M., Scharre, D. W., Bell, E. H., Honig, L. S., Vonsattel, J. P., Serrano, G. E., Beach, T. G., Karch, C. M., … Fu, H. (2025). GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58585-w

Li, B. I., Alvarez, M. J., Zhao, H., Chirathivat, N., Califano, A., & Shen, M. M. (2025). The regulatory architecture of the primed pluripotent cell state. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57894-4

Hoffman, S. S., Tang, Z., Dunlop, A., Brennan, P. A., Huynh, T., Eick, S. M., Barr, D. B., Rushing, B., McRitchie, S. L., Sumner, S., Taibl, K. R., Tan, Y., Panuwet, P., Lee, G. E., Eatman, J., Corwin, E. J., Ryan, P. B., Jones, D. P., & Liang, D. (2025). Impact of prenatal phthalate exposure on newborn metabolome and infant neurodevelopment. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57273-z

Lu, C., Kang, T., Zhang, J., Yang, K., Liu, Y., Song, K., Lin, Q., Dixit, D., Gimple, R. C., Zhang, Q., Shi, Z., Fan, X., Wu, Q., Li, D., Shan, D., Gao, J., Gu, D., You, H., Li, Y., … Wang, X. (2025). Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58366-5

Zhao, J., Gu, T., Gao, C., Miao, G., Palma-Gudiel, H., Yu, L., Yang, J., Wang, Y., Li, Y., Lim, J., Li, R., Yao, B., Wu, H., Schneider, J. A., Seyfried, N., Grodstein, F., De Jager, P. L., Jin, P., & Bennett, D. A. (2025). Brain 5-hydroxymethylcytosine alterations are associated with Alzheimer’s disease neuropathology. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58159-w

Nixon-Abell, J., Ruggeri, F. S., Qamar, S., Herling, T. W., Czekalska, M. A., Shen, Y., Wang, G., King, C., Fernandopulle, M. S., Sneideris, T., Watson, J. L., Pillai, V. V. S., Meadows, W., Henderson, J. W., Chambers, J. E., Wagstaff, J. L., Williams, S. H., Coyle, H., Šneiderienė, G., … St George-Hyslop, P. (2025). ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58142-5

Jiang, W., Jaehnig, E. J., Liao, Y., Shi, Z., Yaron-Barir, T. M., Johnson, J. L., Cantley, L. C., & Zhang, B. (2025). Deciphering the dark cancer phosphoproteome using machine-learned co-regulation of phosphosites. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57993-2

Singh, D., Robin, T., Urbakh, M., & Reuveni, S. (2025). High-order Michaelis-Menten equations allow inference of hidden kinetic parameters in enzyme catalysis. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57327-2

Mangione, R. M., Pierce, S., Zheng, M., Martin, R. M., Goncalves, C., Kumar, A., Scaglione, S., de Sousa Morgado, C., Penzo, A., Lancrey, A., Reid, R. J. D., Lautier, O., Gaillard, P.-H., Stirling, P. C., de Almeida, S. F., Rothstein, R., & Palancade, B. (2025). DNA lesions can frequently precede DNA:RNA hybrid accumulation. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57588-x

Kim, J., Williams, A., Noh, H., Jasper, E. A., Jones, S. H., Jaworski, J. A., Shuey, M. M., Ruiz-Narváez, E. A., Wise, L. A., Palmer, J. R., Connolly, J., Keaton, J. M., Denny, J. C., Khan, A., Abbass, M. A., Rasmussen-Torvik, L. J., Kottyan, L. C., Madhivanan, P., Krupp, K., … Hellwege, J. N. (2025). Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57483-5

Vann, K. R., Sharma, R., Hsu, C.-C., Devoucoux, M., Tencer, A. H., Zeng, L., Lin, K., Zhu, L., Li, Q., Lachance, C., Ospina, R. R., Tong, Q., Cheung, K. L., Yang, S., Biswas, S., Xuan, H., Gatchalian, J., Alamillo, L., Wang, J., … Kutateladze, T. G. (2025). Structure-function relationship of ASH1L and histone H3K36 and H3K4 methylation. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57556-5

Loffredo, L. F., Kustagi, A., Ringham, O. R., Li, F., de los Santos-Alexis, K., Saqi, A., & Arpaia, N. (2025). Heparan sulfate regulates amphiregulin programming of tissue reparative lung mesenchymal cells during influenza A virus infection in mice. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57362-z

Rubinelli, L., Manzo, O. L., Sungho, J., Del Gaudio, I., Bareja, R., Marino, A., Palikhe, S., Di Mauro, V., Bucci, M., Falcone, D. J., Elemento, O., Ersoy, B., Diano, S., Sasset, L., & Di Lorenzo, A. (2025). Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56869-9

Arnold, M., Buyukozkan, M., Doraiswamy, P. M., Nho, K., Wu, T., Gudnason, V., Launer, L. J., Wang-Sattler, R., Adamski, J., De Jager, P. L., Ertekin-Taner, N., Bennett, D. A., Saykin, A. J., Peters, A., Suhre, K., Kaddurah-Daouk, R., Kastenmüller, G., & Krumsiek, J. (2025). Individual bioenergetic capacity as a potential source of resilience to Alzheimer’s disease. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57032-0

Yuan, F., Yang, J., Ma, F., Hu, Z., Malik, V., Zang, R., Li, D., Shi, X., Huang, X., Zhou, H., & Wang, J. (2025). Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57165-2

Mitchell, J., Camacho, N., Shea, P., Stopsack, K. H., Joseph, V., Burren, O. S., Dhindsa, R. S., Nag, A., Berchuck, J. E., O’Neill, A., Abbasi, A., Zoghbi, A. W., Alegre-Díaz, J., Kuri-Morales, P., Berumen, J., Tapia-Conyer, R., Emberson, J., Torres, J. M., Collins, R., … Fabre, M. A. (2025). Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56944-1

Di Matteo, F., Bonrath, R., Pravata, V., Schmidt, H., Ayo Martin, A. C., Di Giaimo, R., Menegaz, D., Riesenberg, S., de Vrij, F. M. S., Maccarrone, G., Holzapfel, M., Straub, T., Kushner, S. A., Robertson, S. P., Eder, M., & Cappello, S. (2025). Neuronal hyperactivity in neurons derived from individuals with gray matter heterotopia. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56998-1

Zhang, P., Du, Q., Wang, Y., Wei, L., & Wang, X. (2025). Systematic representation and optimization enable the inverse design of cross-species regulatory sequences in bacteria. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57031-1

Dharmadhikari, A. V., Abad, M. A., Khan, S., Maroofian, R., Sands, T. T., Ullah, F., Samejima, I., Shen, Y., Wear, M. A., Moore, K. E., Kondakova, E., Mitina, N., Schaub, T., Lee, G. K., Umandap, C. H., Berger, S. M., Iglesias, A. D., Popp, B., Abou Jamra, R., … Liao, J. (2025). RNA methyltransferase SPOUT1/CENP-32 links mitotic spindle organization with the neurodevelopmental disorder SpADMiSS. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56876-w

Craig-Schapiro, R., Li, G., Chen, K., Gomez-Salinero, J. M., Nachman, R., Kopacz, A., Schreiner, R., Chen, X., Zhou, Q., Rafii, S., & Redmond, D. (2025). Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55415-3

Mondal, J., Zhang, J., Qing, F., Li, S., Kumar, D., Huse, J. T., & Giancotti, F. G. (2025). Brd7 loss reawakens dormant metastasis initiating cells in lung by forging an immunosuppressive niche. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56347-2

Doron-Mandel, E., Bokor, B. J., Ma, Y., Street, L. A., Tang, L. C., Abdou, A. A., Shah, N. H., Rosenberger, G., & Jovanovic, M. (2025). SEC-MX: an approach to systematically study the interplay between protein assembly states and phosphorylation. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56303-0

Guo, M. H., Lee, W.-P., Vardarajan, B., Schellenberg, G. D., & Phillips-Cremins, J. E. (2025). Polygenic burden of short tandem repeat expansions promotes risk for Alzheimer’s disease. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56400-0

Zhang, D., Zhang, B., Wu, Q., Zhou, T., Tong, J., Lu, Y., Chen, J., Wang, H., Chisolm, D. J., Jhaveri, R., Kenney, R. C., Rothman, R. L., Rao, S., Williams, D. A., Hornig, M., Wang, L., Morris, J. S., Forrest, C. B., & Chen, Y. (2025). Racial/ethnic differences in post-acute sequelae of SARS-CoV-2 in children and adolescents in the United States. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55273-z

Wang, Z., Liu, Z., Fang, Y., Zhang, H. H., Sun, X., Hao, N., Que, J., & Ding, H. (2025). Training data diversity enhances the basecalling of novel RNA modification-induced nanopore sequencing readouts. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-55974-z

Wisniewski, D. J., Ma, L., Rauhala, O. J., Cea, C., Zhao, Z., Ranschaert, A., Gelinas, J. N., & Khodagholy, D. (2025). Spatial control of doping in conducting polymers enables complementary, conformable, implantable internal ion-gated organic electrochemical transistors. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55284-w

Park, J., Karnati, H., Rustgi, S. D., Hur, C., Kong, X.-F., & Kastrinos, F. (2025). Impact of population screening for Lynch syndrome insights from the All of Us data. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-52562-5

Larrea, D., Tamucci, K. A., Kabra, K., Velasco, K. R., Yun, T. D., Pera, M., Montesinos, J., Agrawal, R. R., Paradas, C., Smerdon, J. W., Lowry, E. R., Stepanova, A., Yoval-Sanchez, B., Galkin, A., Wichterle, H., & Area-Gomez, E. (2025). Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS). Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-51578-1

Duan, S., Nodelman, I. M., Zhou, H., Tsukiyama, T., Bowman, G. D., & Zhang, Z. (2025). H3K56 acetylation regulates chromatin maturation following DNA replication. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55144-7

Liu, H., Zask, A., Forouhar, F., Iketani, S., Williams, A., Vaz, D. R., Habashi, D., Choi, K., Resnick, S. J., Hong, S. J., Lovett, D. H., Bai, T., Chavez, A., Ho, D. D., & Stockwell, B. R. (2025). Development of small molecule non-covalent coronavirus 3CL protease inhibitors from DNA-encoded chemical library screening. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55421-5

Kizhatil, K., Clark, G. M., Sunderland, D. K., Bhandari, A., Horbal, L. J., Balasubramanian, R., & John, S. W. M. (2025). FYN regulates aqueous humor outflow and IOP through the phosphorylation of VE-CADHERIN. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55232-8

Shi, X., Li, Y., Zhou, H., Hou, X., Yang, J., Malik, V., Faiola, F., Ding, J., Bao, X., Modic, M., Zhang, W., Chen, L., Mahmood, S. R., Apostolou, E., Yang, F.-C., Xu, M., Xie, W., Huang, X., Chen, Y., & Wang, J. (2024). DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-55054-8

Stein, M. N., Dumbrava, E. E., Teply, B. A., Gergis, U. S., Guiterrez, M. E., Reshef, R., Subudhi, S. K., Jacquemont, C. F., Senesac, J. H., Bayle, J. H., Scripture, C. D., Chatwal, M. S., Bilen, M. A., Stadler, W. M., & Becerra, C. R. (2024). PSCA-targeted BPX-601 CAR T cells with pharmacological activation by rimiducid in metastatic pancreatic and prostate cancer: a phase 1 dose escalation trial. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-53220-6

Pedroni, A., Yilmaz, E., Del Vecchio, L., Bhattarai, P., Vidal, I. T., Dai, Y.-W. E., Koutsogiannis, K., Kizil, C., & Ampatzis, K. (2024). Decoding the molecular, cellular, and functional heterogeneity of zebrafish intracardiac nervous system. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-54830-w