Nature Communications
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Schaffer, E. S., Mishra, N., Whiteway, M. R., Li, W., Vancura, M. B., Freedman, J., Patel, K. B., Voleti, V., Paninski, L., Hillman, E. M. C., Abbott, L. F., & Axel, R. (2023). The spatial and temporal structure of neural activity across the fly brain. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-41261-2
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Zuckerman Mind, Brain, and Behavior Institute; Department of Neuroscience; Vagelos College of Physicians and Surgeons; Department of Biochemistry and Molecular Biophysics; Department of Pathology and Cell Biology; Department of Radiology; Department of Physiology and Cellular Biophysics; Grossman Center for the Statistics of Mind
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Neuberger, A., Trofimov, Y. A., Yelshanskaya, M. V., Khau, J., Nadezhdin, K. D., Khosrof, L. S., Krylov, N. A., Efremov, R. G., & Sobolevsky, A. I. (2023). Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-40362-2
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Nadezhdin, K. D., Talyzina, I. A., Parthasarathy, A., Neuberger, A., Zhang, D. X., & Sobolevsky, A. I. (2023). Structure of human TRPV4 in complex with GTPase RhoA. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-39346-z
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Bergman, S., Cater, R. J., Plante, A., Mancia, F., & Khelashvili, G. (2023). Substrate binding-induced conformational transitions in the omega-3 fatty acid transporter MFSD2A. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-39088-y
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Neuberger, A., Trofimov, Y. A., Yelshanskaya, M. V., Nadezhdin, K. D., Krylov, N. A., Efremov, R. G., & Sobolevsky, A. I. (2023). Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-38352-5
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Nadezhdin, K. D., Correia, L., Narangoda, C., Patel, D. S., Neuberger, A., Gudermann, T., Kurnikova, M. G., Chubanov, V., & Sobolevsky, A. I. (2023). Structural mechanisms of TRPM7 activation and inhibition. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-38362-3
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Neuberger, A., Oda, M., Nikolaev, Y. A., Nadezhdin, K. D., Gracheva, E. O., Bagriantsev, S. N., & Sobolevsky, A. I. (2023). Human TRPV1 structure and inhibition by the analgesic SB-366791. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-38162-9
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Ayaz, P., Lyczek, A., Paung, Y., Mingione, V. R., Iacob, R. E., de Waal, P. W., Engen, J. R., Seeliger, M. A., Shan, Y., & Shaw, D. E. (2023). Structural mechanism of a drug-binding process involving a large conformational change of the protein target. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-36956-5
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Xue, N., Liu, X., Zhang, D., Wu, Y., Zhong, Y., Wang, J., Fan, W., Jiang, H., Zhu, B., Ge, X., Gonzalez, R. V. L., Chen, L., Zhang, S., She, P., Zhong, Z., Sun, J., Chen, X., Wang, L., Gu, Z., … Zhang, X. (2023). Improving adenine and dual base editors through introduction of TadA-8e and Rad51DBD. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-36887-1
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Glasgow, A., Hobbs, H. T., Perry, Z. R., Wells, M. L., Marqusee, S., & Kortemme, T. (2023). Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-36798-1
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Huang, J., Huffman, J. E., Huang, Y., Do Valle, Í., Assimes, T. L., Raghavan, S., Voight, B. F., Liu, C., Barabási, A.-L., Huang, R. D. L., Hui, Q., Nguyen, X.-M. T., Ho, Y.-L., Djousse, L., Lynch, J. A., Vujkovic, M., Tcheandjieu, C., Tang, H., Damrauer, S. M., … O’Donnell, C. J. (2022). Genomics and phenomics of body mass index reveals a complex disease network. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-35553-2
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Shi, J., Wu, X., Wang, Z., Li, F., Meng, Y., Moore, R. M., Cui, J., Xue, C., Croce, K. R., Yurdagul, A., Doench, J. G., Li, W., Zarbalis, K. S., Tabas, I., Yamamoto, A., & Zhang, H. (2022). A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-35604-8
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Arter, W. E., Qi, R., Erkamp, N. A., Krainer, G., Didi, K., Welsh, T. J., Acker, J., Nixon-Abell, J., Qamar, S., Guillén-Boixet, J., Franzmann, T. M., Kuster, D., Hyman, A. A., Borodavka, A., George-Hyslop, P. S., Alberti, S., & Knowles, T. P. J. (2022). Biomolecular condensate phase diagrams with a combinatorial microdroplet platform. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-35265-7
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Lim, R. G., Al-Dalahmah, O., Wu, J., Gold, M. P., Reidling, J. C., Tang, G., Adam, M., Dansu, D. K., Park, H.-J., Casaccia, P., Miramontes, R., Reyes-Ortiz, A. M., Lau, A., Hickman, R. A., Khan, F., Paryani, F., Tang, A., Ofori, K., Miyoshi, E., … Thompson, L. M. (2022). Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-35388-x
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Nunnelly, L. F., Campbell, M., Lee, D. I., Dummer, P., Gu, G., Menon, V., & Au, E. (2022). St18 specifies globus pallidus projection neuron identity in MGE lineage. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-35518-5
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Morgenstern, T. J., Nirwan, N., Hernández-Ochoa, E. O., Bibollet, H., Choudhury, P., Laloudakis, Y. D., Ben Johny, M., Bannister, R. A., Schneider, M. F., Minor, D. L., & Colecraft, H. M. (2022). Selective posttranslational inhibition of CaVβ1-associated voltage-dependent calcium channels with a functionalized nanobody. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-35025-7
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Kameda-Smith, M. M., Zhu, H., Luo, E.-C., Suk, Y., Xella, A., Yee, B., Chokshi, C., Xing, S., Tan, F., Fox, R. G., Adile, A. A., Bakhshinyan, D., Brown, K., Gwynne, W. D., Subapanditha, M., Miletic, P., Picard, D., Burns, I., Moffat, J., … Singh, S. K. (2022). Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-35118-3
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Martinez-Morata, I., Bostick, B. C., Conroy-Ben, O., Duncan, D. T., Jones, M. R., Spaur, M., Patterson, K. P., Prins, S. J., Navas-Acien, A., & Nigra, A. E. (2022). Nationwide geospatial analysis of county racial and ethnic composition and public drinking water arsenic and uranium. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-35185-6
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Dinh, T. T., Xiang, M., Rajaraman, A., Wang, Y., Salazar, N., Zhu, Y., Roper, W., Rhee, S., Brulois, K., O’Hara, E., Kiefel, H., Dinh, T. M., Bi, Y., Gonzalez, D., Bao, E. P., Red-Horse, K., Balogh, P., Gábris, F., Gaszner, B., … Butcher, E. C. (2022). An NKX-COUP-TFII morphogenetic code directs mucosal endothelial addressin expression. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34991-2
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Zhou, R. W., Xu, J., Martin, T. C., Zachem, A. L., He, J., Ozturk, S., Demircioglu, D., Bansal, A., Trotta, A. P., Giotti, B., Gryder, B., Shen, Y., Wu, X., Carcamo, S., Bosch, K., Hopkins, B., Tsankov, A., Steinhagen, R., Jones, D. R., … Parsons, R. E. (2022). A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33377-8
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Kurniansyah, N., Goodman, M. O., Kelly, T. N., Elfassy, T., Wiggins, K. L., Bis, J. C., Guo, X., Palmas, W., Taylor, K. D., Lin, H. J., Haessler, J., Gao, Y., Shimbo, D., Smith, J. A., Yu, B., Feofanova, E. V., Smit, R. A. J., Wang, Z., Hwang, S.-J., … Sofer, T. (2022). A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31080-2
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Winans, S., Yu, H. J., de los Santos, K., Wang, G. Z., KewalRamani, V. N., & Goff, S. P. (2022). A point mutation in HIV-1 integrase redirects proviral integration into centromeric repeats. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29097-8
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de Sena-Tomás, C., Aleman, A. G., Ford, C., Varshney, A., Yao, D., Harrington, J. K., Saúde, L., Ramialison, M., & Targoff, K. L. (2022). Activation of Nkx2.5 transcriptional program is required for adult myocardial repair. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30468-4
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Park, J., Li, J., Mayer, J. P., Ball, K. A., Wu, J., Hall, C., Accili, D., Stowell, M. H. B., Bai, X., & Choi, E. (2022). Activation of the insulin receptor by an insulin mimetic peptide. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33274-0
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Rabadan, M. A., De La Cruz, E. D., Rao, S. B., Chen, Y., Gong, C., Crabtree, G., Xu, B., Markx, S., Gogos, J. A., Yuste, R., & Tomer, R. (2022). An in vitro model of neuronal ensembles. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31073-1
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Primakov, S. P., Ibrahim, A., van Timmeren, J. E., Wu, G., Keek, S. A., Beuque, M., Granzier, R. W. Y., Lavrova, E., Scrivener, M., Sanduleanu, S., Kayan, E., Halilaj, I., Lenaers, A., Wu, J., Monshouwer, R., Geets, X., Gietema, H. A., Hendriks, L. E. L., Morin, O., … Lambin, P. (2022). Automated detection and segmentation of non-small cell lung cancer computed tomography images. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30841-3
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Lee, A., Kondapalli, C., Virga, D. M., Lewis, T. L., Koo, S. Y., Ashok, A., Mairet-Coello, G., Herzig, S., Foretz, M., Viollet, B., Shaw, R., Sproul, A., & Polleux, F. (2022). Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32130-5
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Filippone, M. G., Gaglio, D., Bonfanti, R., Tucci, F. A., Ceccacci, E., Pennisi, R., Bonanomi, M., Jodice, G., Tillhon, M., Montani, F., Bertalot, G., Freddi, S., Vecchi, M., Taglialatela, A., Romanenghi, M., Romeo, F., Bianco, N., Munzone, E., Sanguedolce, F., … Pece, S. (2022). CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30375-8
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Meister, J., Bone, D. B. J., Knudsen, J. R., Barella, L. F., Velenosi, T. J., Akhmedov, D., Lee, R. J., Cohen, A. H., Gavrilova, O., Cui, Y., Karsenty, G., Chen, M., Weinstein, L. S., Kleinert, M., Berdeaux, R., Jensen, T. E., Richter, E. A., & Wess, J. (2022). Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells. Nature Communications, 13(1). https://doi.org/10.1038/s41467-021-27540-w
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Uddin, M. d M., Nguyen, N. Q. H., Yu, B., Brody, J. A., Pampana, A., Nakao, T., Fornage, M., Bressler, J., Sotoodehnia, N., Weinstock, J. S., Honigberg, M. C., Nachun, D., Bhattacharya, R., Griffin, G. K., Chander, V., Gibbs, R. A., Rotter, J. I., Liu, C., Baccarelli, A. A., … Conneely, K. N. (2022). Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33093-3
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Chadwick, F. J., Clark, J., Chowdhury, S., Chowdhury, T., Pascall, D. J., Haddou, Y., Andrecka, J., Kundegorski, M., Wilkie, C., Brum, E., Shirin, T., Alamgir, A. S. M., Rahman, M., Alam, A. N., Khan, F., Swallow, B., Mair, F. S., Illian, J., Trotter, C. L., … Sania, A. (2022). Combining rapid antigen testing and syndromic surveillance improves community-based COVID-19 detection in a low-income country. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30640-w
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Pei, S., Kandula, S., Cascante Vega, J., Yang, W., Foerster, S., Thompson, C., Baumgartner, J., Ahuja, S. D., Blaney, K., Varma, J. K., Long, T., & Shaman, J. (2022). Contact tracing reveals community transmission of COVID-19 in New York City. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34130-x
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Teng, S., Zhen, F., Wang, L., Schalchli, J. C., Simko, J., Chen, X., Jin, H., Makinson, C. D., & Peng, Y. (2022). Control of non-REM sleep by ventrolateral medulla glutamatergic neurons projecting to the preoptic area. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32461-3
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Tran, V.-T., Porcher, R., Pane, I., & Ravaud, P. (2022). Course of post COVID-19 disease symptoms over time in the ComPaRe long COVID prospective e-cohort. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29513-z
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Xie, K., Fuchs, H., Scifo, E., Liu, D., Aziz, A., Aguilar-Pimentel, J. A., Amarie, O. V., Becker, L., da Silva-Buttkus, P., Calzada-Wack, J., Cho, Y.-L., Deng, Y., Edwards, A. C., Garrett, L., Georgopoulou, C., Gerlini, R., Hölter, S. M., Klein-Rodewald, T., Kramer, M., … Ehninger, D. (2022). Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34515-y
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Sasako, T., Umehara, T., Soeda, K., Kaneko, K., Suzuki, M., Kobayashi, N., Okazaki, Y., Tamura-Nakano, M., Chiba, T., Accili, D., Kahn, C. R., Noda, T., Asahara, H., Yamauchi, T., Kadowaki, T., & Ueki, K. (2022). Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33008-2
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Liu, H., Iketani, S., Zask, A., Khanizeman, N., Bednarova, E., Forouhar, F., Fowler, B., Hong, S. J., Mohri, H., Nair, M. S., Huang, Y., Tay, N. E. S., Lee, S., Karan, C., Resnick, S. J., Quinn, C., Li, W., Shion, H., Xia, X., … Stockwell, B. R. (2022). Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29413-2
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Vagelos College of Physicians and Surgeons; Department of Medicine; Division of Infectious Diseases; Herbert Irving Comprehensive Cancer Center; Aaron Diamond AIDS Research Center; Department of Microbiology and Immunology; Department of Pathology and Cell Biology; JP Sulzberger Columbia Genome Center; Department of Molecular Pharmacology and Therapeutics
Duong, M. T., Das, S. R., Lyu, X., Xie, L., Richardson, H., Xie, S. X., Yushkevich, P. A., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J. C., … Nasrallah, I. M. (2022). Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-28941-1
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Wielscher, M., Mandaviya, P. R., Kuehnel, B., Joehanes, R., Mustafa, R., Robinson, O., Zhang, Y., Bodinier, B., Walton, E., Mishra, P. P., Schlosser, P., Wilson, R., Tsai, P.-C., Palaniswamy, S., Marioni, R. E., Fiorito, G., Cugliari, G., Karhunen, V., Ghanbari, M., … Järvelin, M.-R. (2022). DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29792-6
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Kalmbach, A., Winiger, V., Jeong, N., Asok, A., Gallistel, C. R., Balsam, P. D., & Simpson, E. H. (2022). Dopamine encodes real-time reward availability and transitions between reward availability states on different timescales. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31377-2
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Wang, X., Vincent, E., Siddiqui, S., Turnbull, K., Lu, H., Blair, R., Wu, X., Watkins, M., Ziani, W., Shao, J., Doyle-Meyers, L. A., Russell-Lodrigue, K. E., Bohm, R. P., Veazey, R. S., & Xu, H. (2022). Early treatment regimens achieve sustained virologic remission in infant macaques infected with SIV at birth. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32554-z
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Boyé, K., Geraldo, L. H., Furtado, J., Pibouin-Fragner, L., Poulet, M., Kim, D., Nelson, B., Xu, Y., Jacob, L., Maissa, N., Agalliu, D., Claesson-Welsh, L., Ackerman, S. L., & Eichmann, A. (2022). Endothelial Unc5B controls blood-brain barrier integrity. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-28785-9
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Liu, L., Khan, A., Sanchez-Rodriguez, E., Zanoni, F., Li, Y., Steers, N., Balderes, O., Zhang, J., Krithivasan, P., LeDesma, R. A., Fischman, C., Hebbring, S. J., Harley, J. B., Moncrieffe, H., Kottyan, L. C., Namjou-Khales, B., Walunas, T. L., Knevel, R., Raychaudhuri, S., … Kiryluk, K. (2022). Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34456-6
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Levin, M. G., Tsao, N. L., Singhal, P., Liu, C., Vy, H. M. T., Paranjpe, I., Backman, J. D., Bellomo, T. R., Bone, W. P., Biddinger, K. J., Hui, Q., Dikilitas, O., Satterfield, B. A., Yang, Y., Morley, M. P., Bradford, Y., Burke, M., Reza, N., Charest, B., … Damrauer, S. M. (2022). Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34216-6
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Sing, C. N., Garcia, E. J., Lipkin, T. G., Huckaba, T. M., Tsang, C. A., Coughlin, A. C., Yang, E. J., Boldogh, I. R., Higuchi-Sanabria, R., & Pon, L. A. (2022). Identification of a modulator of the actin cytoskeleton, mitochondria, nutrient metabolism and lifespan in yeast. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30045-9
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Lin, C., Yang, Q., Guo, D., Xie, J., Yang, Y.-S., Chaugule, S., DeSouza, N., Oh, W.-T., Li, R., Chen, Z., John, A. A., Qiu, Q., Zhu, L. J., Greenblatt, M. B., Ghosh, S., Li, S., Gao, G., Haynes, C., Emerson, C. P., & Shim, J.-H. (2022). Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-34694-8
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Baran, N., Lodi, A., Dhungana, Y., Herbrich, S., Collins, M., Sweeney, S., Pandey, R., Skwarska, A., Patel, S., Tremblay, M., Kuruvilla, V. M., Cavazos, A., Kaplan, M., Warmoes, M. O., Veiga, D. T., Furudate, K., Rojas-Sutterin, S., Haman, A., Gareau, Y., … Konopleva, M. (2022). Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30396-3
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Fabian, P., Tseng, K.-C., Thiruppathy, M., Arata, C., Chen, H.-J., Smeeton, J., Nelson, N., & Crump, J. G. (2022). Lifelong single-cell profiling of cranial neural crest diversification in zebrafish. Nature Communications, 13(1). https://doi.org/10.1038/s41467-021-27594-w
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Marie, L., & Symington, L. S. (2022). Mechanism for inverted-repeat recombination induced by a replication fork barrier. Nature Communications, 13(1). https://doi.org/10.1038/s41467-021-27443-w
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Huang, H., Pan, W., Wang, Y., Kim, H. S., Shao, D., Huang, B., Ho, T.-C., Lao, Y.-H., Quek, C. H., Shi, J., Chen, Q., Shi, B., Zhang, S., Zhao, L., & Leong, K. W. (2022). Nanoparticulate cell-free DNA scavenger for treating inflammatory bone loss in periodontitis. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33492-6
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