Mutant PfCRT Can Mediate Piperaquine Resistance in African Plasmodium falciparum with Reduced Fitness and Increased Susceptibility to Other Antimalarials

Wicht, K. J., Small-Saunders, J. L., Hagenah, L. M., Mok, S., & Fidock, D. A. (2022). Mutant PfCRT Can Mediate Piperaquine Resistance in African Plasmodium falciparum With Reduced Fitness and Increased Susceptibility to Other Antimalarials. The Journal of Infectious Diseases, 226(11), 2021–2029. https://doi.org/10.1093/infdis/jiac365
Authors:
Kathryn J. Wicht
Jennifer L. Small-Saunders
Laura M. Hagenah
Sachel Mok
David A. Fidock
Affiliated Authors:
Kathryn J. Wicht
Jennifer L. Small-Saunders
Laura M. Hagenah
Sachel Mok
David A. Fidock
Columbia Affiliation:
Subjects:
Antimalarials (MeSH)
Malaria, Falciparum (MeSH)
Plasmodium falciparum (MeSH)
Quinolines (MeSH)
Author Keywords:
antimalarial drug resistance
artemisinin-based combination therapy
pfcrt mutations
piperaquine resistance
plasmodium falciparum
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Publication Type:
Article
Unique ID:
10.1093/infdis/jiac365
PMID:
36082431
DOI:
10.1093/infdis/jiac365
Journal:
Journal of Infectious Diseases
Publication Date:
Data Source:
Scopus
Source Link:
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Record Created: