Dietary tryptophan deficiency promotes gut RORγt+ Treg cells at the expense of Gata3+ Treg cells and alters commensal microbiota metabolism

Rankin, L. C., Kaiser, K. A., de los Santos-Alexis, K., Park, H., Uhlemann, A.-C., Gray, D. H. D., & Arpaia, N. (2023). Dietary tryptophan deficiency promotes gut RORγt+ Treg cells at the expense of Gata3+ Treg cells and alters commensal microbiota metabolism. Cell Reports, 42(3), 112135. https://doi.org/10.1016/j.celrep.2023.112135
Authors:
Lucille C. Rankin
Katherine A. Kaiser
Kenia de los Santos-Alexis
Heekuk Park
Anne‐Catrin Uhlemann
Daniel H.D. Gray
Nicholas Arpaia
Affiliated Authors:
Lucille C. Rankin
Katherine A. Kaiser
Kenia de los Santos-Alexis
Heekuk Park
Anne‐Catrin Uhlemann
Nicholas Arpaia
Columbia Affiliation:
Subjects:
T-Lymphocytes, Regulatory (MeSH)
Microbiota (MeSH)
Diversity and Function of Gut Microbiome (OpenAlex Topic)
Salutogenesis and Sense of Coherence in Health (OpenAlex Topic)
Innate Lymphoid Cells in Immunity (OpenAlex Topic)
Author Keywords:
aryl hydrocarbon receptor
cp: immunology
cp: metabolism
gut inflammation
intestinal tregs
microbiota
mucosal immunity
nutrient deficiency
tryptophan metabolism
elink
Publication Type:
Article
Unique ID:
10.1016/j.celrep.2023.112135
PMID:
36840944
DOI:
10.1016/j.celrep.2023.112135
Journal:
Cell Reports
Publication Date:
Data Source:
OpenAlex
Source Link:
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