Department of Medicine

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Domingo-Relloso, A., McGraw, K. E., Heckbert, S. R., Luchsinger, J. A., Schilling, K., Glabonjat, R. A., Martinez-Morata, I., Mayer, M., Liu, Y., Wood, A. C., Goldsmith, J., Hayden, K. M., Habes, M., Nasrallah, I. M., Bryan, R. N., Rashid, T., Post, W. S., Rotter, J. I., Palta, P., … Navas-Acien, A. (2024). Urinary Metal Levels, Cognitive Test Performance, and Dementia in the Multi-Ethnic Study of Atherosclerosis. JAMA Network Open, 7(12), e2448286. https://doi.org/10.1001/jamanetworkopen.2024.48286
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Abozenah, M., Nazir, N. T., Sareen, N., Brandt, E., Pack, Q. R., Ibebuogu, U., Shetty, M., Singh, K., Stecker, E. C., & Yang, E. (2024). Tobacco Use, Electronic Nicotine Delivery Systems, and Vulnerable Populations. JACC: Advances, 3(11), 101362. https://doi.org/10.1016/j.jacadv.2024.101362
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Miller, W. C., Wallace, S., Kamm, W., Reardon, E., Theis-Mahon, N., Yousefzadeh, M. J., Schmidt, E. L., Niedernhofer, L. J., & Puskarich, M. A. (2024). Cellular senescence in acute human infectious disease: a systematic review. Frontiers in Aging, 5. https://doi.org/10.3389/fragi.2024.1500741
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Luchsinger, J. A., Feldman, H. H., Messer, K., Edland, S. D., Leger, G. C., Jacobs, D. M., Salmon, D. P., Revta, C., Lupo, J., Durant, J., & Gibson, G. E. (2024). A Seamless Phase 2A‐Phase 2B Multi‐Center Trial to Test the Benefits of Benfotiamine on the Progression of Alzheimer’s Disease‐Benfoteam: Design and Methods. Alzheimer’s & Dementia, 20(S6). Portico. https://doi.org/10.1002/alz.091963
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Paulrasu, K., Gokulan, R. C., El-Rifai, W., Chen, Z., Que, J., Wang, T. C., Boutaud, O. G., Briegel, K., Dikalov, S. I., Garcia-Buitrago, M. T., & Zaika, A. I. (2024). Chronic gastroesophageal reflux dysregulates proteostasis in esophageal epithelial cells. Cellular and Molecular Gastroenterology and Hepatology, 101434. https://doi.org/10.1016/j.jcmgh.2024.101434
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Henick, B. S., Koch, P. D., Gainor, J. F., Awad, M. M., Chiuzan, C., Izard, S., Georgis, Y., Mallick, S., Garofano, R. F., Wong, C. V., Saqi, A., Grindheim, J., Schulze, K., Sonett, J. R., Rizvi, N. A., Izar, B., Taylor, A. M., & Shu, C. A. (2024). Neoadjuvant atezolizumab + chemotherapy for resectable NSCLC: 3-year clinical update of phase II clinical trial results and translational findings. Journal for ImmunoTherapy of Cancer, 12(12), e009301. https://doi.org/10.1136/jitc-2024-009301
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McKeague, M. L., Lohmueller, J., Dracz, M. T., Saadallah, N., Ricci, E. D., Beckwith, D. M., Ayyalasomayajula, R., Cudic, M., & Finn, O. J. (2024). Preventative Cancer Vaccine-Elicited Human Anti-MUC1 Antibodies Have Multiple Effector Functions. Antibodies, 13(4), 85. https://doi.org/10.3390/antib13040085
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He, Q., Wang, W., Xu, D., Xiong, Y., Tao, C., You, C., Ma, L., Ma, J., Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C.-Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Logue, M. W., … Koenen, K. C. (2024). Potential causal association between gut microbiome and posttraumatic stress disorder. Translational Psychiatry, 14(1). https://doi.org/10.1038/s41398-024-02765-7
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Rudolph, M. D., Tanley, J. E., Ding, J., Chen, H., Hayden, K. M., Liu, Y., Bryan, R. N., Nasrallah, I. M., Dolui, S., Habes, M., Luchsinger, J. A., Heckbert, S. R., Lockhart, S. N., & Hughes, T. M. (2024). Subclinical Vascular Risk Composites and Dementia Imaging Biomarkers 17‐20 years later in the Multi‐Ethnic Study of Atherosclerosis (MESA). Alzheimer’s & Dementia, 20(S7). Portico. https://doi.org/10.1002/alz.089603
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Slotwiner, D. J., Serwer, G. A., Allred, J. D., Bhakta, D., Clark, R., Durand, J., Ferrara, M. G., Hale, J., Irving, C., Iverson, A., Jin, M., Johansen, J. B., Kalscheur, M., Krisjnen, D., Lerman, R., Lippman, N., Mendenhall, G. S., Michael, R., Nichols, S., … Wadhwa, M. (2024). 2024 HRS perspective on advancing workflows for CIED remote monitoring. Heart Rhythm O2, 5(12), 845–853. https://doi.org/10.1016/j.hroo.2024.09.012
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Noble, J. M., Minchala, S. G., Hedmann, M. G., Teresi, J., Ocepek‐Welikson, K., Silver, S. A., Eimicke, J. P., Ramirez, M., Harris, A., Lloyd, A., Chhea, K., Arango, C. A., Lee, Y., Sawyer, V., & Williams, O. (2024). Development of the 7‐item ASK‐AD Assess Symptoms and Knowledge of Alzheimer’s Disease tool for multigenerational community dementia awareness: Findings from Old SCHOOL Hip Hop. Alzheimer’s & Dementia, 20(S7). Portico. https://doi.org/10.1002/alz.089722
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Charisis, S., Rashid, T., Dintica, C. S., Gonzales, M. M., Liu, H., Ware, J. B., Austin, T. R., Jensen, P. N., Fohner, A. E., Tanley, J. E., Ding, J., Luchsinger, J. A., Sachs, B. C., Nasrallah, I. M., Bryan, R. N., Hayden, K. M., Wolk, D. A., Rascovsky, K., Davatzikos, C., … Habes, M. (2024). Modelling Small Vessel Disease Using Regional MRI Markers, and Mediating Effects on Cognitive Decline. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.086725
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Hajduczok, A. G., Stives, D., Fabbri, M., Donald, E. M., Maning, J., & Mentz, R. J. (2024). Windy City Breakthroughs: Highlights from the American Heart Association Scientific Sessions 2024. Journal of Cardiac Failure. https://doi.org/10.1016/j.cardfail.2024.11.006
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Gibson, G. E., Flowers, S. A., Feldman, H. H., Luchsinger, J. A., & Zhang, S. (2024). Pharmacological thiamine (Vitamin B1) as a treatment for alzheimer’s disease. Alzheimer’s & Dementia, 20(S6). Portico. https://doi.org/10.1002/alz.086468
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Nishiwaki, N., Sugiura, K., Suzuki, K., Li, A. L., Contreras, C. T., Efe, G., Shin, A. E., Sadeghian, D., Zhao, J., Maitra, A., Pitarresi, J. R., Sims, P. A., Chandwani, R., & Rustgi, A. K. (2024). PRRX1 has functional roles in pancreatic acinar to ductal metaplasia and carcinogenesis. Cellular and Molecular Gastroenterology and Hepatology, 101442. https://doi.org/10.1016/j.jcmgh.2024.101442
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Tretter, J. T., Bedogni, F., Rodés-Cabau, J., Regueiro, A., Testa, L., Eleid, M. F., Chen, S., Galhardo, A., Ellenbogen, K. A., Leon, M. B., & Ben-Haim, S. (2024). Novel cardiac CT method for identifying the atrioventricular conduction axis by anatomic landmarks. Heart Rhythm. https://doi.org/10.1016/j.hrthm.2024.12.022
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Vonk Noordegraaf, A., & Bogaard, H. J. (2024). The lung that rules the heart. European Respiratory Journal, 64(6), 2401922. https://doi.org/10.1183/13993003.01922-2024
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Franceschini, N., Feldman, D. L., Berg, J. S., Besse, W., Chang, A. R., Dahl, N. K., Gbadegesin, R., Pollak, M. R., Rasouly, H. M., Smith, R. J. H., Winkler, C. A., Gharavi, A. G., Ars, E., Reza Bekheirnia, M., Bier, L., Bleyer, A. J., Fuller, L. J., Halbritter, J., Harris, P. C., … Wong, C. S. (2024). Advancing Genetic Testing in Kidney Diseases: Report From a National Kidney Foundation Working Group. American Journal of Kidney Diseases, 84(6), 751–766. https://doi.org/10.1053/j.ajkd.2024.05.010
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Miller, P., Elias, P., Einstein, A. J., Maurer, M. S., Ahmed, G. Y., & Poterucha, T. J. (2024). Socioeconomic Disparities Are Associated With Delayed Access to Tafamidis in Transthyretin Cardiac Amyloidosis. Circulation: Heart Failure, 17(12). https://doi.org/10.1161/circheartfailure.124.012075
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Tanley, J. E., Jaeger, B. C., Chen, H., Rudolph, M. D., Sachs, B. C., Li, C., Rascovsky, K., Luchsinger, J. A., Hayden, K. M., Ding, J., Liu, Y., Bertoni, A. G., Heckbert, S. R., Post, W., Szklo, M., Lockhart, S. N., & Hughes, T. M. (2024). Subclinical Vascular Disorders in Relation to Cognitive Decline and Impairment: The Multi‐Ethnic Study of Atherosclerosis. Alzheimer’s & Dementia, 20(S7). Portico. https://doi.org/10.1002/alz.089209
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Sardar, P., Granada, J. F., & Cannon, L. A. (2024). Revitalizing Innovation. JACC: Basic to Translational Science, 9(12), 1435–1439. https://doi.org/10.1016/j.jacbts.2024.08.006
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Devanand, D., Lee, S., Knopman, D. S., Vassilaki, M., Luchsinger, J. A., & Motter, J. N. (2024). Comparison of olfactory and cognitive measures to neuroimaging biomarkers in the prediction of cognitive decline and dementia in the MCSA cohort. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.084722
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Emala, C. W., Saroya, T. K., Miao, Y., Wang, S., Sang, S., & DiMango, E. A. (2024). Low-Dose Oral Ginger Improves Daily Symptom Scores in Asthma. Pharmaceuticals, 17(12), 1651. https://doi.org/10.3390/ph17121651
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Hojjati, S. H., Butler, T. A., de Leon, M. J., Gupta, A. H., Nayak, S., Luchsinger, J. A., Chiang, G., & Razlighi, Q. R. (2024). Remote associations between beta‐amyloid and tau are mediated by between‐network connectivity. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.086460
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Ciaccio, E. J., Hsia, H. H., Robinson, D., Cedilnik, N., Zeldin, L., Wan, E. Y., Biviano, A. B., Yarmohammadi, H., & Saluja, D. S. (2024). Uniform slow conduction during sinus rhythm and low voltage/low voltage gradient ΔV/V characterize the VT isthmus location. Heart Rhythm. https://doi.org/10.1016/j.hrthm.2024.11.051
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Luchsinger, J. A. (2024). Design, Characteristics, and Resources from the Diabetes Prevention Program Outcomes Study (DPPOS) AD/ADRD project. Alzheimer’s & Dementia, 20(S7). Portico. https://doi.org/10.1002/alz.086325
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Bestgen, B., Jones, S., Thathy, V., Kuemmerle, A., Barcelo, C., Haouala, A., Gossen, D., Marx, M. W., Di Resta, I., Szramowska, M., Webster, R. A., Llewellyn, S., Ritacco, D. A., Yeo, T., Leroy, D., Barber, B. E., Fidock, D. A., Griffin, P., Lickliter, J., & Chalon, S. (2024). Safety, tolerability, pharmacokinetics, and antimalarial activity of MMV533: a phase 1a first-in-human, randomised, ascending dose and food effect study, and a phase 1b Plasmodium falciparum volunteer infection study. The Lancet Infectious Diseases. https://doi.org/10.1016/s1473-3099(24)00664-9
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Adams, D. H., Tang, G. H. L., Whisenant, B. K., Kodali, S. K., Singh, G. D., Fam, N. P., Kar, S., Price, M. J., Spies, C., Schwartz, J. G., Makkar, R. R., Tadros, P., Asgar, A. W., Jorde, U. P., Benza, R. L., Thourani, V. H., McCarthy, P. M., Bae, R., Smith, T. W. R., … Sorajja, P. (2024). Transcatheter Edge-to-Edge Repair in Patients With Complex Tricuspid Valve Anatomy. JACC: Cardiovascular Interventions, 17(23), 2749–2760. https://doi.org/10.1016/j.jcin.2024.08.035
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Chester, J. G., Carcamo, B., Gudis, D. A., Bustamante, D., Eisig, S. B., Ombrello, M. J., Chung, W. K., & Milner, J. D. (2024). PLCG2 variants in cherubism. Journal of Allergy and Clinical Immunology, 154(6), 1554–1558. https://doi.org/10.1016/j.jaci.2024.08.016
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Luchsinger, J. A., Valdez, L., Rosario, D., Eimicke, J. P., Silver, S. A., Kong, J. X., Teresi, J., Goldberg, T. E., & Devanand, D. (2024). Performance of a smell identification test vs. the mini‐mental status exam for the detection of dementia and cognitive impairment among ethnically diverse persons with cognitive concerns in primary care. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092026
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Faust, H. J., Cheng, T.-Y., Korsunsky, I., Watts, G. F. M., Gal-Oz, S. T., Trim, W. V., Kongthong, S., Jonsson, A. H., Simmons, D. P., Zhang, F., Padera, R., Chubinskaya, S., Albrecht, J., Anolik, J. H., Apruzzese, W., Barnas, J. L., Bathon, J. M., Ben-Artzi, A., … Brenner, M. B. (2024). Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52586-x
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DeConne, T. M., Williams, J. R., Pewowaruk, R., Korcarz, C. E., Tanley, J. E., Carlsson, C. M., Heckbert, S. R., Habes, M., Nasrallah, I. M., Lockhart, S. N., Luchsinger, J. A., Ding, J., Liu, Y., Hayden, K. M., Gepner, A. D., & Hughes, T. M. (2024). Total and Structural Carotid Artery Stiffness are related to Cognitive Decline and ADRD Pathology: The Multi‐Ethnic Study of Atherosclerosis (MESA). Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.089226
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South, A. M., Giammattei, V. C., Bagley, K. W., Bakhoum, C. Y., Beasley, W. H., Bily, M. B., Biswas, S., Bridges, A. M., Byfield, R. L., Campbell, J. F., Chanchlani, R., Chen, A., D’Agostino McGowan, L., Downs, S. M., Fergeson, G. M., Greenberg, J. H., Hill-Horowitz, T. A., Jensen, E. T., Kallash, M., … Weaver, D. J. (2024). The Study of the Epidemiology of Pediatric Hypertension Registry (SUPERHERO): rationale and methods. American Journal of Epidemiology, 193(12), 1650–1661. https://doi.org/10.1093/aje/kwae116
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Wang, Q., Guo, Y., Schwanz, L. T., Mellis, I. A., Sun, Y., Qu, Y., Urtecho, G., Valdez, R., Stoneman, E., Gordon, A., Wang, H. H., Ho, D. D., & Liu, L. (2024). SARS-CoV-2 omicron BA.2.87.1 exhibits higher susceptibility to serum neutralization than EG.5.1 and JN.1. Emerging Microbes & Infections, 13(1). https://doi.org/10.1080/22221751.2024.2359004
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Charisis, S., Rashid, T., Dintica, C. S., Gonzales, M. M., Liu, H., Ware, J. B., Austin, T. R., Jensen, P. N., Fohner, A. E., Tanley, J. E., Ding, J., Luchsinger, J. A., Sachs, B. C., Nasrallah, I. M., Bryan, R. N., Hayden, K. M., Wolk, D. A., Rascovsky, K., Davatzikos, C., … Habes, M. (2024). Modelling Small Vessel Disease Using Regional MRI Markers, and Mediating Effects on Cognitive Decline. Alzheimer’s & Dementia, 20(S9). Portico. https://doi.org/10.1002/alz.093701
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Luo, Y., Hanuska, D., Xu, J., Salvatore, M. M., & Bernstein, E. J. (2025). Quantification of coronary artery calcification in systemic sclerosis using visual ordinal and deep learning scoring: Association with systemic sclerosis clinical features. Seminars in Arthritis and Rheumatism, 70, 152598. https://doi.org/10.1016/j.semarthrit.2024.152598
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Reveiz, M., Xu, K., Lee, M., Wang, S., Olia, A. S., Harris, D. R., Liu, K., Liu, T., Schaub, A. J., Stephens, T., Wang, Y., Zhang, B., Huang, R., Tsybovsky, Y., Kwong, P. D., & Rawi, R. (2024). Vaccine-elicited and naturally elicited antibodies differ in their recognition of the HIV-1 fusion peptide. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1484029
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Lopez, R., Mohan, S., Rodrigue, J. R., Arrigain, S., Brosi, D., Lavanchy, R., Kaplan, B., Pomfret, E. A., & Schold, J. D. (2024). Association of organ procurement organization volume with Centers for Medicare and Medicaid Services performance evaluations. American Journal of Transplantation. https://doi.org/10.1016/j.ajt.2024.11.024
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Hu, Y., Zhang, W., Ali, S. R., Takeda, K., Vahl, T. P., Zhu, D., Hong, Y., & Cheng, K. (2024). Extracellular vesicle therapeutics for cardiac repair. Journal of Molecular and Cellular Cardiology. https://doi.org/10.1016/j.yjmcc.2024.11.005
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Boudreaux, B. D., Schwartz, J. E., Romero, E. K., & Diaz, K. M. (2024). Reallocations of Time Between Sleep, Sedentary Behavior, and Physical Activity and Their Associations With 24-Hour Blood Pressure. American Journal of Hypertension. https://doi.org/10.1093/ajh/hpae149
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Luth, M. R., Godinez-Macias, K. P., Chen, D., Okombo, J., Thathy, V., Cheng, X., Daggupati, S., Davies, H., Dhingra, S. K., Economy, J. M., Edgar, R. C. S., Gomez-Lorenzo, M. G., Istvan, E. S., Jado, J. C., LaMonte, G. M., Melillo, B., Mok, S., Narwal, S. K., Ndiaye, T., … Winzeler, E. A. (2024). Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance. Science, 386(6725). https://doi.org/10.1126/science.adk9893
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Tarun, S., Mellis, I. A., Kilic, A., Green, D. A., Tokiwa, M., Berry, G. J., Wu, F., & Shah, S. S. (2024). Incidental identification of neonatal babesiosis: a case report. BMC Pediatrics, 24(1). https://doi.org/10.1186/s12887-024-05219-7
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Chaput, J.-P., Biswas, R. K., Ahmadi, M., Cistulli, P. A., Rajaratnam, S. M. W., Bian, W., St-Onge, M.-P., & Stamatakis, E. (2024). Sleep regularity and major adverse cardiovascular events: a device-based prospective study in 72 269 UK adults. Journal of Epidemiology and Community Health, jech-2024-222795. https://doi.org/10.1136/jech-2024-222795
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Martinelli, E., Westland, R., A. Olabisi, O., & Sanna-Cherchi, S. (2024). Prevalence and Impact of APOL1 Kidney Risk Variants in West Africa. Journal of the American Society of Nephrology. https://doi.org/10.1681/asn.0000000587
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Askanase, A. D., D’Cruz, D., Kalunian, K., Merrill, J. T., Navarra, S. V., Cahuzac, C., Cornelisse, P., Murphy, M. J., Strasser, D. S., Trokan, L., & Berkani, O. (2024). Cenerimod, a sphingosine-1-phosphate receptor modulator, versus placebo in patients with moderate-to-severe systemic lupus erythematosus (CARE): an international, double-blind, randomised, placebo-controlled, phase 2 trial. The Lancet Rheumatology. https://doi.org/10.1016/s2665-9913(24)00246-7
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Manrique-Caballero, C. L., Barasch, J., Zaidi, S. K., Bates, C. M., Ray, E. C., Kleyman, T. R., & Al-Bataineh, M. M. (2024). Expression and Distribution of MUC1 in the Developing and Adult Kidney. American journal of physiology. Renal physiology, Advance online publication.

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Geng, J., Ruan, X., Wu, X., Chen, X., Fu, T., Gill, D., Burgess, S., Chen, J., Ludvigsson, J. F., Larsson, S. C., Li, X., Du, Z., & Yuan, S. (2024). Network Mendelian randomisation analysis deciphers protein pathways linking type 2 diabetes and gastrointestinal disease. Diabetes, Obesity and Metabolism. Portico. https://doi.org/10.1111/dom.16087
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Zahr, T., Li, T., Bhansali, D., Wan, Q., Leong, K. W., & Qiang, L. (2024). Targeted delivery of a cationic dendrimer with a plaque-homing peptide for the treatment of atherosclerosis. Life Medicine. https://doi.org/10.1093/lifemedi/lnae039
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