Columbia Stem Cell Initiative

Displaying 51 - 100 of 121CSV
Zhang, Y., Zhang, W., Zhao, J., Ito, T., Jin, J., Aparicio, A. O., Zhou, J., Guichard, V., Fang, Y., Que, J., Urban, J. F., Hanna, J. H., Ghosh, S., Wu, X., Ding, L., Basu, U., & Huang, Y. (2023). m6A RNA modification regulates innate lymphoid cell responses in a lineage-specific manner. Nature Immunology, 24(8), 1256–1264. https://doi.org/10.1038/s41590-023-01548-4
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Viragova, S., Aparicio, L., Palmerini, P., Zhao, J., Valencia Salazar, L. E., Schurer, A., Dhuri, A., Sahoo, D., Moskaluk, C. A., Rabadan, R., & Dalerba, P. (2023). Inverse agonists of retinoic acid receptor/retinoid X receptor signaling as lineage-specific antitumor agents against human adenoid cystic carcinoma. JNCI: Journal of the National Cancer Institute, 115(7), 838–852. https://doi.org/10.1093/jnci/djad062
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Occelli, L. M., Zobel, L., Stoddard, J., Wagner, J., Pasmanter, N., Querubin, J., Renner, L. M., Reynaga, R., Winkler, P. A., Sun, K., Marinho, L. F. L. P., O’Riordan, C. R., Frederick, A., Lauer, A., Tsang, S. H., Hauswirth, W. W., McGill, T. J., Neuringer, M., Michalakis, S., & Petersen-Jones, S. M. (2023). Development of a translatable gene augmentation therapy for CNGB1-retinitis pigmentosa. Molecular Therapy, 31(7), 2028–2041. https://doi.org/10.1016/j.ymthe.2023.04.005
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Rahman, S., Lan, X., Terranova, C., El-Kholdi, R., Yilmaz, O. H., & Cheng, C.-W. (2023). Epigenetic and Transcriptional Dynamics of Notch Program in Intestinal Differentiation. Intestinal Differentiated Cells, 77–88. https://doi.org/10.1007/978-1-0716-3076-1_7
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Botta, S., de Prisco, N., Chemiakine, A., Brandt, V., Cabaj, M., Patel, P., Doron‐Mandel, E., Treadway, C. J., Jovanovic, M., Brown, N. G., Soni, R. K., & Gennarino, V. A. (2023). Dosage sensitivity to Pumilio1 variants in the mouse brain reflects distinct molecular mechanisms. The EMBO Journal, 42(11). Portico. https://doi.org/10.15252/embj.2022112721
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Chang, Y.-J., Jenny, L. A., Li, Y.-S., Cui, X., Kong, Y., Li, Y., Sparrow, J. R., & Tsang, S. H. (2023). CRISPR editing demonstrates rs10490924 raised oxidative stress in iPSC-derived retinal cells from patients with ARMS2/HTRA1 -related AMD. Proceedings of the National Academy of Sciences, 120(19). https://doi.org/10.1073/pnas.2215005120
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Ong, H. W., Liang, Y., Richardson, W., Lowry, E. R., Wells, C. I., Chen, X., Silvestre, M., Dempster, K., Silvaroli, J. A., Smith, J. L., Wichterle, H., Pabla, N. S., Ultanir, S. K., Bullock, A. N., Drewry, D. H., & Axtman, A. D. (2023). Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS Chemical Neuroscience, 14(9), 1672–1685. https://doi.org/10.1021/acschemneuro.3c00135
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Breazzano, M. P., Oh, J. K., Batson, S. A., Kucherich, J. A., Karani, R., Rohrmann, C. M., Sparrow, J. R., Fragiotta, S., & Tsang, S. H. (2022). Vitamin A deficiency and the retinal “double carrot” sign with optical coherence tomography. Eye, 37(7), 1489–1495. https://doi.org/10.1038/s41433-022-02137-9
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Ngo, W. K., Fisher, Y. L., Silverman, R. H., Tsang, S. H., & Spaide, R. F. (2023). Scleral Thickness in Autosomal Dominant Best Vitelliform Macular Dystrophy. RETINAL Cases & Brief Reports. https://doi.org/10.1097/icb.0000000000001433
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Ling, J., Jenny, L. A., Zhou, A., & Tsang, S. H. (2022). Therapeutic Gene Editing in Inherited Retinal Disorders. Cold Spring Harbor Perspectives in Medicine, 13(4), a041292. https://doi.org/10.1101/cshperspect.a041292
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Wu, Y.-C., Kissner, M., & Momen-Heravi, F. (2023). A comprehensive multiparameter flow cytometry panel for immune profiling and functional studies of frozen tissue, bone marrow, and spleen. Journal of Immunological Methods, 515, 113444. https://doi.org/10.1016/j.jim.2023.113444
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Cossu, G., Tonlorenzi, R., Brunelli, S., Sampaolesi, M., Messina, G., Azzoni, E., Benedetti, S., Biressi, S., Bonfanti, C., Bragg, L., Camps, J., Cappellari, O., Cassano, M., Ciceri, F., Coletta, M., Covarello, D., Crippa, S., Cusella-De Angelis, M. G., De Angelis, L., … Ugarte, G. (2023). Mesoangioblasts at 20: From the embryonic aorta to the patient bed. Frontiers in Genetics, 13. https://doi.org/10.3389/fgene.2022.1056114
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Sui, L., Du, Q., Romer, A., Su, Q., Chabosseau, P. L., Xin, Y., Kim, J., Kleiner, S., Rutter, G. A., & Egli, D. (2023). ZnT8 Loss of Function Mutation Increases Resistance of Human Embryonic Stem Cell-Derived Beta Cells to Apoptosis in Low Zinc Condition. Cells, 12(6), 903. https://doi.org/10.3390/cells12060903
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Iannello, G., Patel, A., Sirabella, D., Diaz, A. G., Hoover, B. N., Sarmah, H., & Corneo, B. (2023). Simple, Fast, and Efficient Method for Derivation of Dermal Fibroblasts From Skin Biopsies. Current Protocols, 3(3). Portico. https://doi.org/10.1002/cpz1.714
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de Prisco, N., Ford, C., Elrod, N. D., Lee, W., Tang, L. C., Huang, K.-L., Lin, A., Ji, P., Jonnakuti, V. S., Boyle, L., Cabaj, M., Botta, S., Õunap, K., Reinson, K., Wojcik, M. H., Rosenfeld, J. A., Bi, W., Tveten, K., Prescott, T., … Gennarino, V. A. (2023). Alternative polyadenylation alters protein dosage by switching between intronic and 3′UTR sites. Science Advances, 9(7). https://doi.org/10.1126/sciadv.ade4814
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Kong, Y., Liu, P., Li, Y., Nolan, N. D., Quinn, P. M. J., Hsu, C., Jenny, L. A., Zhao, J., Cui, X., Chang, Y., Wert, K. J., Sparrow, J. R., Wang, N., & Tsang, S. H. (2023). HIF2α activation and mitochondrial deficit due to iron chelation cause retinal atrophy. EMBO Molecular Medicine, 15(2). Portico. https://doi.org/10.15252/emmm.202216525
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Ramos Rego, I., Silvério, D., Eufrásio, M. I., Pinhanços, S. S., Lopes da Costa, B., Teixeira, J., Fernandes, H., Kong, Y., Li, Y., Tsang, S. H., Oliveira, P. J., Fernandes, R., Quinn, P. M. J., Santos, P. F., Ambrósio, A. F., & Alves, C. H. (2023). TRAP1 Is Expressed in Human Retinal Pigment Epithelial Cells and Is Required to Maintain their Energetic Status. Antioxidants, 12(2), 381. https://doi.org/10.3390/antiox12020381
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Lopes da Costa, B., Kolesnikova, M., Levi, S. R., Cabral, T., Tsang, S. H., Maumenee, I. H., & Quinn, P. M. J. (2023). Clinical and Therapeutic Evaluation of the Ten Most Prevalent CRB1 Mutations. Biomedicines, 11(2), 385. https://doi.org/10.3390/biomedicines11020385
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Qian, J., Guan, X., Xie, B., Xu, C., Niu, J., Tang, X., Li, C. H., Colecraft, H. M., Jaenisch, R., & Liu, X. S. (2023). Multiplex epigenome editing of MECP2 to rescue Rett syndrome neurons. Science Translational Medicine, 15(679). https://doi.org/10.1126/scitranslmed.add4666
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Ngo, W. K., Jenny, L. A., Kim, A. H., Kolesnikova, M., Greenstein, V. C., & Tsang, S. H. (2023). Correlations of Full-Field Stimulus Threshold With Functional and Anatomical Outcome Measurements in Advanced Retinitis Pigmentosa. American Journal of Ophthalmology, 245, 155–163. https://doi.org/10.1016/j.ajo.2022.07.010
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Mitchell, C. A., Verovskaya, E. V., Calero-Nieto, F. J., Olson, O. C., Swann, J. W., Wang, X., Hérault, A., Dellorusso, P. V., Zhang, S. Y., Svendsen, A. F., Pietras, E. M., Bakker, S. T., Ho, T. T., Göttgens, B., & Passegué, E. (2023). Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing. Nature Cell Biology, 25(1), 30–41. https://doi.org/10.1038/s41556-022-01053-0
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Tsai, Y.-T., da Costa, B. L., Nolan, N. D., Caruso, S. M., Jenny, L. A., Levi, S. R., Tsang, S. H., & Quinn, P. M. J. (2022). Prime Editing for the Installation and Correction of Mutations Causing Inherited Retinal Disease: A Brief Methodology. Retinitis Pigmentosa, 313–331. https://doi.org/10.1007/978-1-0716-2651-1_29
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Kolesnikova, M., Oh, J. K., Wang, J., Lee, W., Zernant, J., Su, P.-Y., Kim, A. H., Jenny, L. A., Yang, T., Allikmets, R., & Tsang, S. H. (2022). A pathogenic in-frame deletion-insertion variant in BEST1 phenocopies Stargardt disease. JCI Insight, 7(23). https://doi.org/10.1172/jci.insight.162687
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Sena, C., Iannello, G., Skowronski, A. A., Dannheim, K., Cheung, L., Agrawal, P. B., Hirschhorn, J. N., Zeitler, P., LeDuc, C. A., Stratigopoulos, G., & Thaker, V. V. (2022). Endocrine and behavioural features of Lowe syndrome and their potential molecular mechanisms. Journal of Medical Genetics, 59(12), 1171–1178. https://doi.org/10.1136/jmedgenet-2022-108490
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Jenny, L. A., Liu, P.-K., Kolesnikova, M., Duong, J., Kim, A. H., Levi, S. R., Greenstein, V. C., & Tsang, S. H. (2022). Foveolar thickness as potential standardized structural outcome measurement in studies of Bietti crystalline dystrophy. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-16563-y
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Su, P.-Y., Lee, W., Zernant, J., Tsang, S. H., Nagasaki, T., Corneo, B., & Allikmets, R. (2022). Establishment of the iPSC line CUIMCi005-A from a patient with Stargardt disease for retinal organoid culture. Stem Cell Research, 65, 102973. https://doi.org/10.1016/j.scr.2022.102973
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de Sena-Tomás, C., Aleman, A. G., Ford, C., Varshney, A., Yao, D., Harrington, J. K., Saúde, L., Ramialison, M., & Targoff, K. L. (2022). Activation of Nkx2.5 transcriptional program is required for adult myocardial repair. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30468-4
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Xu, J. J., Chalk, A. M., Wall, M., Langdon, W. Y., Smeets, M. F., & Walkley, C. R. (2022). Srsf2P95H/+ co-operates with loss of TET2 to promote myeloid bias and initiate a chronic myelomonocytic leukemia-like disease in mice. Leukemia, 36(12), 2883–2893. https://doi.org/10.1038/s41375-022-01727-6
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Kim, M., Singh, M., Lee, B.-K., Hibbs, M., Richardson, K., Ellies, L., Wintle, L., Stuart, L. M., Wang, J. Y., Voon, D. C., Blancafort, P., Wang, J., Kim, J., Leedman, P. J., & Woo, A. J. (2022). A MYC-ZNF148-ID1/3 regulatory axis modulating cancer stem cell traits in aggressive breast cancer. Oncogenesis, 11(1). https://doi.org/10.1038/s41389-022-00435-1
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Ganapathi, M., Thomas-Wilson, A., Buchovecky, C., Dharmadhikari, A., Barua, S., Lee, W., Ruan, M. Z. C., Soucy, M., Ragi, S., Tanaka, J., Clark, L. N., Naini, A. B., Liao, J., Mansukhani, M., Tsang, S., & Jobanputra, V. (2022). Clinical exome sequencing for inherited retinal degenerations at a tertiary care center. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-13026-2
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Girach, A., Audo, I., Birch, D. G., Huckfeldt, R. M., Lam, B. L., Leroy, B. P., Michaelides, M., Russell, S. R., Sallum, J. M. F., Stingl, K., Tsang, S. H., & Yang, P. (2022). RNA-based therapies in inherited retinal diseases. Therapeutic Advances in Ophthalmology, 14, 251584142211346. https://doi.org/10.1177/25158414221134602
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Kuwasaki, Y., Suzuki, K., Yu, G., Yamamoto, S., Otabe, T., Kakihara, Y., Nishiwaki, M., Miyake, K., Fushimi, K., Bekdash, R., Shimizu, Y., Narikawa, R., Nakajima, T., Yazawa, M., & Sato, M. (2022). A red light–responsive photoswitch for deep tissue optogenetics. Nature Biotechnology, 40(11), 1672–1679. https://doi.org/10.1038/s41587-022-01351-w
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Li, T., Akinade, T., Zhou, J., Wang, H., Tong, Q., He, S., Rinebold, E., Valencia Salazar, L. E., Bhansali, D., Zhong, Y., Ruan, J., Du, J., Dalerba, P., & Leong, K. W. (2022). Therapeutic Nanocarriers Inhibit Chemotherapy‐Induced Breast Cancer Metastasis. Advanced Science, 9(33). Portico. https://doi.org/10.1002/advs.202203949
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Malik, V., Zang, R., Fuentes-Iglesias, A., Huang, X., Li, D., Fidalgo, M., Zhou, H., & Wang, J. (2022). Comparative functional genomics identifies unique molecular features of EPSCs. Life Science Alliance, 5(11), e202201608. https://doi.org/10.26508/lsa.202201608
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Xu, J., Song, F., Lyu, H., Kobayashi, M., Zhang, B., Zhao, Z., Hou, Y., Wang, X., Luan, Y., Jia, B., Stasiak, L., Wong, J. H., Wang, Q., Jin, Q., Jin, Q., Fu, Y., Yang, H., Hardison, R. C., Dovat, S., … Yue, F. (2022). Subtype-specific 3D genome alteration in acute myeloid leukaemia. Nature, 611(7935), 387–398. https://doi.org/10.1038/s41586-022-05365-x
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Wang, S.-H., Hao, J., Zhang, C., Duan, F.-F., Chiu, Y.-T., Shi, M., Huang, X., Yang, J., Cao, H., & Wang, Y. (2022). KLF17 promotes human naive pluripotency through repressing MAPK3 and ZIC2. Science China Life Sciences, 65(10), 1985–1997. https://doi.org/10.1007/s11427-021-2076-x
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Yeaton, A., Cayanan, G., Loghavi, S., Dolgalev, I., Leddin, E. M., Loo, C. E., Torabifard, H., Nicolet, D., Wang, J., Corrigan, K., Paraskevopoulou, V., Starczynowski, D. T., Wang, E., Abdel-Wahab, O., Viny, A. D., Stone, R. M., Byrd, J. C., Guryanova, O. A., Kohli, R. M., … Guillamot, M. (2022). The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation. Cancer Discovery, 12(10), 2392–2413. https://doi.org/10.1158/2159-8290.cd-21-1146
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Capaccione, K. M., Doubrovin, M., Braumuller, B., Leibowitz, D., Bhatt, N., Momen-Heravi, F., Molotkov, A., Kissner, M., Goldner, K., Soffing, M., Ali, A., & Mintz, A. (2022). Evaluating the Combined Anticancer Response of Checkpoint Inhibitor Immunotherapy and FAP-Targeted Molecular Radiotherapy in Murine Models of Melanoma and Lung Cancer. Cancers, 14(19), 4575. https://doi.org/10.3390/cancers14194575
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Caballero, M., Ge, T., Rebelo, A. R., Seo, S., Kim, S., Brooks, K., Zuccaro, M., Kanagaraj, R., Vershkov, D., Kim, D., Smogorzewska, A., Smolka, M., Benvenisty, N., West, S. C., Egli, D., Mace, E. M., & Koren, A. (2022). Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role forMCM10in replication timing regulation. Human Molecular Genetics, 31(17), 2899–2917. https://doi.org/10.1093/hmg/ddac082
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Patel, A., Iannello, G., Diaz, A. G., Sirabella, D., Thaker, V., & Corneo, B. (2022). Efficient Cas9‐based Genome Editing Using CRISPR Analysis Webtools in Severe Early‐onset‐obesity Patient‐derived iPSCs. Current Protocols, 2(8). Portico. https://doi.org/10.1002/cpz1.519
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Palmerola, K. L., Amrane, S., De Los Angeles, A., Xu, S., Wang, N., de Pinho, J., Zuccaro, M. V., Taglialatela, A., Massey, D. J., Turocy, J., Robles, A., Subbiah, A., Prosser, B., Lobo, R., Ciccia, A., Koren, A., Baslan, T., & Egli, D. (2022). Replication stress impairs chromosome segregation and preimplantation development in human embryos. Cell, 185(16), 2988-3007.e20. https://doi.org/10.1016/j.cell.2022.06.028
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Cui, X., Kim, H. J., Cheng, C.-H., Jenny, L. A., Lima de Carvalho, J. R., Chang, Y.-J., Kong, Y., Hsu, C.-W., Huang, I.-W., Ragi, S. D., Lin, C.-S., Li, X., Sparrow, J. R., & Tsang, S. H. (2022). Long-term vitamin A supplementation in a preclinical mouse model forRhoD190N-associated retinitis pigmentosa. Human Molecular Genetics, 31(14), 2438–2451. https://doi.org/10.1093/hmg/ddac032
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Hein, R. F. C., Wu, J. H., Holloway, E. M., Frum, T., Conchola, A. S., Tsai, Y.-H., Wu, A., Fine, A. S., Miller, A. J., Szenker-Ravi, E., Yan, K. S., Kuo, C. J., Glass, I., Reversade, B., & Spence, J. R. (2022). R-SPONDIN2 mesenchymal cells form the bud tip progenitor niche during human lung development. Developmental Cell, 57(13), 1598-1614.e8. https://doi.org/10.1016/j.devcel.2022.05.010
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