Replication stress impairs chromosome segregation and preimplantation development in human embryos

Palmerola, K. L., Amrane, S., De Los Angeles, A., Xu, S., Wang, N., de Pinho, J., Zuccaro, M. V., Taglialatela, A., Massey, D. J., Turocy, J., Robles, A., Subbiah, A., Prosser, B., Lobo, R., Ciccia, A., Koren, A., Baslan, T., & Egli, D. (2022). Replication stress impairs chromosome segregation and preimplantation development in human embryos. Cell, 185(16), 2988-3007.e20. https://doi.org/10.1016/j.cell.2022.06.028
Authors:
Katherine L. Palmerola
Selma Amrane
Alejandro De Los Angeles
Shuangyi Xu
Ning Wang
Joao de Pinho
Michael V. Zuccaro
Angelo Taglialatela
Dashiell J. Massey
Jenna Turocy
Alex Robles
Anisa Subbiah
Bob Prosser
Rogerio Lobo
Alberto Ciccia
Amnon Koren
Timour Baslan
Dieter Egli
Affiliated Authors:
Katherine L. Palmerola
Selma Amrane
Alejandro De Los Angeles
Shuangyi Xu
Ning Wang
Joao de Pinho
Michael V. Zuccaro
Angelo Taglialatela
Jenna Turocy
Alex Robles
Anisa Subbiah
Bob Prosser
Rogerio Lobo
Alberto Ciccia
Dieter Egli
Author Keywords:
chromosomal mosaicism
chromosome fragility
developmental arrest
double-strand break
gene-poor regions
incomplete replication
micronuclei
preimplantation development
replication stress
stalled replication forks
Publication Type:
Article
Unique ID:
10.1016/j.cell.2022.06.028
PMID:
Journal:
Publication Date:
Data Source:
Scopus

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