HIF2α activation and mitochondrial deficit due to iron chelation cause retinal atrophy

Kong, Y., Liu, P., Li, Y., Nolan, N. D., Quinn, P. M. J., Hsu, C., Jenny, L. A., Zhao, J., Cui, X., Chang, Y., Wert, K. J., Sparrow, J. R., Wang, N., & Tsang, S. H. (2023). HIF2α activation and mitochondrial deficit due to iron chelation cause retinal atrophy. EMBO Molecular Medicine, 15(2). Portico. https://doi.org/10.15252/emmm.202216525
Authors:
Yang Kong
Pei-Kang Liu
Yao Li
Nicholas D Nolan
Peter M J Quinn
Chun-Wei Hsu
Laura A Jenny
Jin Zhao
Xuan Cui
Ya-Ju Chang
Katherine J Wert
Janet R Sparrow
Nan-Kai Wang
Stephen H Tsang
Affiliated Authors:
Yang Kong
Pei-Kang Liu
Yao Li
Nicholas D Nolan
Peter M J Quinn
Chun-Wei Hsu
Laura A Jenny
Jin Zhao
Xuan Cui
Ya-Ju Chang
Janet R Sparrow
Nan-Kai Wang
Stephen H Tsang
Subjects:
Author Keywords:
hif2 alpha upregulation
iron deficiency
mitochondrial deficit
rpe atrophy
alpha-ketoglutarate
hif2α upregulation
α-ketoglutarate
Publication Type:
Article
Unique ID:
10.15252/emmm.202216525
PMID:
Publication Date:
Data Source:
PubMed

Record Created: