Permanent neonatal diabetes-causing insulin mutations have dominant negative effects on beta cell identity

Zhang, Y., Sui, L., Du, Q., Haataja, L., Yin, Y., Viola, R., Xu, S., Nielsson, C. U., Leibel, R. L., Barbetti, F., Arvan, P., & Egli, D. (2024). Permanent neonatal diabetes-causing insulin mutations have dominant negative effects on beta cell identity. Molecular Metabolism, 80, 101879. https://doi.org/10.1016/j.molmet.2024.101879
Authors:
Yuwei Zhang
Lina Sui
Qian Du
Leena Haataja
Yishu Yin
Ryan Viola
Shuangyi Xu
Christian Ulrik Nielsson
Rudolph L Leibel
Fabrizio Barbetti
Peter Arvan
Dieter Egli
Affiliated Authors:
Yuwei Zhang
Lina Sui
Qian Du
Yishu Yin
Ryan Viola
Shuangyi Xu
Christian Ulrik Nielsson
Rudolph L Leibel
Dieter Egli
Columbia Affiliation:
Subjects:
Insulin (MeSH)
Diabetes Mellitus (MeSH)
Author Keywords:
insulin
er stress
ips cells
gene correction
cell therapy
beta cell de-differentiation
permanent neonatal diabetes
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Publication Type:
Article
Unique ID:
10.1016/j.molmet.2024.101879
PMID:
38237895
DOI:
10.1016/j.molmet.2024.101879
Journal:
Molecular Metabolism
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created: