Cell Stem Cell
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Hong, J., Sui, P., Li, Y., Xu, K. Y., Lee, J.-H., Wang, J., Chen, S., Zhang, P., Wingate, N., Noor, A., Yuan, Y., Hromas, R., Zhou, H., Hamamoto, K., Su, R., Yin, C. C., Ye, F., Quesada, A. E., Chen, J., … Xu, M. (2025). PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1. Cell Stem Cell. https://doi.org/10.1016/j.stem.2025.01.010
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Columbia Affiliation
Mosialou, I., & Kousteni, S. (2024). From brain to blood and back again: Linking chronic stress, myelopoiesis, and depression. Cell Stem Cell, 31(12), 1721–1723. https://doi.org/10.1016/j.stem.2024.11.012
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Yang, L., Han, Y., Zhang, T., Dong, X., Ge, J., Roy, A., Zhu, J., Lu, T., Jeya Vandana, J., de Silva, N., Robertson, C. C., Xiang, J. Z., Pan, C., Sun, Y., Que, J., Evans, T., Liu, C., Wang, W., Naji, A., … Chen, S. (2024). Human vascularized macrophage-islet organoids to model immune-mediated pancreatic β cell pyroptosis upon viral infection. Cell Stem Cell. https://doi.org/10.1016/j.stem.2024.08.007
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Columbia Affiliation
Xu, L., Tan, C., Barr, J., Talaba, N., Verheyden, J., Chin, J. S., Gaboyan, S., Kasaraneni, N., Elgamal, R. M., Gaulton, K. J., Lin, G., Afshar, K., Golts, E., Meier, A., Alexander, L. E. C., Borok, Z., Shen, Y., Chung, W. K., McCulley, D. J., & Sun, X. (2024). Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells. Cell Stem Cell. https://doi.org/10.1016/j.stem.2024.08.001
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Columbia Affiliation
Kirk, J. S., Wang, J., Long, M., Rosario, S., Tracz, A., Ji, Y., Kumar, R., Liu, X., Jamroze, A., Singh, P. K., Puzanov, I., Chatta, G., Cheng, Q., Huang, J., Wrana, J. L., Lovell, J., Yu, H., Liu, S., Shen, M. M., … Tang, D. G. (2024). Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells. Cell Stem Cell, 31(8), 1203-1221.e7. https://doi.org/10.1016/j.stem.2024.05.008
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Columbia Affiliation
Al-Dalahmah, O., Lam, M., McInvale, J. J., Qu, W., Nguyen, T., Mun, J.-Y., Kwon, S., Ifediora, N., Mahajan, A., Humala, N., Winters, T., Angeles, E., Jakubiak, K. A., Kühn, R., Kim, Y. A., De Rosa, M. C., Doege, C. A., Paryani, F., Flowers, X., … Hargus, G. (2024). Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons. Cell Stem Cell, 31(5), 676-693.e10. https://doi.org/10.1016/j.stem.2024.03.013
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Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Neurosurgery; Department of Pediatrics; Division of Molecular Genetics; Department of Pathology and Cell Biology; Aaron Diamond AIDS Research Center; Department of Neurology; Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; Center for Translational and Computational Neuroimmunology
Yang, L., Kim, T. W., Han, Y., Nair, M. S., Harschnitz, O., Zhu, J., Wang, P., Koo, S. Y., Lacko, L. A., Chandar, V., Bram, Y., Zhang, T., Zhang, W., He, F., Pan, C., Wu, J., Huang, Y., Evans, T., van der Valk, P., … Chen, S. (2024). SARS-CoV-2 infection causes dopaminergic neuron senescence. Cell Stem Cell, 31(2), 196-211.e6. https://doi.org/10.1016/j.stem.2023.12.012
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Columbia Affiliation
MacCarthy, C. M., Wu, G., Malik, V., Menuchin-Lasowski, Y., Velychko, T., Keshet, G., Fan, R., Bedzhov, I., Church, G. M., Jauch, R., Cojocaru, V., Schöler, H. R., & Velychko, S. (2024). Highly cooperative chimeric super-SOX induces naive pluripotency across species. Cell Stem Cell, 31(1), 127-147.e9. https://doi.org/10.1016/j.stem.2023.11.010
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Columbia Affiliation
Kasbekar, M., Mitchell, C. A., Proven, M. A., & Passegué, E. (2023). Hematopoietic stem cells through the ages: A lifetime of adaptation to organismal demands. Cell Stem Cell, 30(11), 1403–1420. https://doi.org/10.1016/j.stem.2023.09.013
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Ruscitto, A., Chen, P., Tosa, I., Wang, Z., Zhou, G., Safina, I., Wei, R., Morel, M. M., Koch, A., Forman, M., Reeve, G., Lecholop, M. K., Wilson, M., Bonthius, D., Chen, M., Ono, M., Wang, T. C., Yao, H., & Embree, M. C. (2023). Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity. Cell Stem Cell, 30(9), 1179-1198.e7. https://doi.org/10.1016/j.stem.2023.08.004
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Columbia Affiliation
College of Dental Medicine; Section of Growth and Development; Division of Orthodontics; Columbia Stem Cell Initiative; Section of Hospital Dentistry; Division of Oral and Maxillofacial Surgery; Division of Digestive and Liver Diseases; Department of Medicine; Vagelos College of Physicians and Surgeons
Jiang, Z., Wu, F., Laise, P., Takayuki, T., Na, F., Kim, W., Kobayashi, H., Chang, W., Takahashi, R., Valenti, G., Sunagawa, M., White, R. A., Macchini, M., Renz, B. W., Middelhoff, M., Hayakawa, Y., Dubeykovskaya, Z. A., Tan, X., Chu, T. H., … Wang, T. C. (2023). Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis. Cell Stem Cell, 30(8), 1091-1109.e7. https://doi.org/10.1016/j.stem.2023.07.002
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Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Medicine; Division of Digestive and Liver Diseases; Department of Systems Biology; Department of Biochemistry and Molecular Biophysics; Department of Biomedical Informatics; Division of Hematology/Oncology; Department of Pathology and Cell Biology
Sarkaria, S. M., Zhou, J., Bao, S., Zhao, W., Fang, Y., Que, J., Bhagat, G., Zhang, C., & Ding, L. (2023). Systematic dissection of coordinated stromal remodeling identifies Sox10 glial cells as a therapeutic target in myelofibrosis. Cell Stem Cell, 30(6), 832-850.e6. https://doi.org/10.1016/j.stem.2023.05.002
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Columbia Affiliation
Center for Stem Cell Therapies; Center for Human Development; Vagelos College of Physicians and Surgeons; Department of Medicine; Division of Digestive and Liver Diseases; Department of Pathology and Cell Biology; Department of Systems Biology; Department of Biochemistry and Molecular Biophysics; Department of Rehabilitation and Regenerative Medicine; Department of Microbiology and Immunology; Columbia Stem Cell Initiative; Division of Hematology/Oncology
Kraiczy, J., McCarthy, N., Malagola, E., Tie, G., Madha, S., Boffelli, D., Wagner, D. E., Wang, T. C., & Shivdasani, R. A. (2023). Graded BMP signaling within intestinal crypt architecture directs self-organization of the Wnt-secreting stem cell niche. Cell Stem Cell, 30(4), 433-449.e8. https://doi.org/10.1016/j.stem.2023.03.004
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Columbia Affiliation
Fan, Y., Hackland, J., Baggiolini, A., Hung, L. Y., Zhao, H., Zumbo, P., Oberst, P., Minotti, A. P., Hergenreder, E., Najjar, S., Huang, Z., Cruz, N. M., Zhong, A., Sidharta, M., Zhou, T., de Stanchina, E., Betel, D., White, R. M., Gershon, M., … Studer, L. (2023). hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung’s disease. Cell Stem Cell, 30(3), 264-282.e9. https://doi.org/10.1016/j.stem.2023.02.003
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Fang, F., Xiao, Y., Zelzer, E., Leong, K. W., & Thomopoulos, S. (2022). A mineralizing pool of Gli1-expressing progenitors builds the tendon enthesis and demonstrates therapeutic potential. Cell Stem Cell, 29(12), 1669-1684.e6. https://doi.org/10.1016/j.stem.2022.11.007
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Columbia Affiliation
Simunovic, M., Siggia, E. D., & Brivanlou, A. H. (2022). In vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells. Cell Stem Cell, 29(6), 962-972.e4. https://doi.org/10.1016/j.stem.2022.05.001
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Kim, H., Kamm, R. D., Vunjak-Novakovic, G., & Wu, J. C. (2022). Progress in multicellular human cardiac organoids for clinical applications. Cell Stem Cell, 29(4), 503–514. https://doi.org/10.1016/j.stem.2022.03.012
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