Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell

Bhattacharya, S., Tie, G., Singh, P. N. P., Malagola, E., Eskiocak, O., He, R., Kraiczy, J., Gu, W., Perlov, Y., Alici-Garipcan, A., Beyaz, S., Wang, T. C., Zhou, Q., & Shivdasani, R. A. (2025). Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell. Cell Stem Cell. https://doi.org/10.1016/j.stem.2025.03.005
Authors:
Swarnabh Bhattacharya
Guodong Tie
Pratik N P Singh
Ermanno Malagola
Onur Eskiocak
Ruiyang He
Judith Kraiczy
Wei Gu
Yakov Perlov
Aybuke Alici-Garipcan
Semir Beyaz
Timothy C Wang
Qiao Zhou
Ramesh A Shivdasani
Affiliated Authors:
Ermanno Malagola
Timothy C Wang
Columbia Affiliation:
Author Keywords:
epigenetic control of cell properties
goblet cells
intestinal epithelial differentiation
intestinal stem cells
lineage plasticity
paneth cells
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Publication Type:
Article
Unique ID:
10.1016/j.stem.2025.03.005
PMID:
40203837
DOI:
10.1016/j.stem.2025.03.005
Journal:
Cell Stem Cell
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created: