Department of Neuroscience

Displaying 1 - 50 of 177CSV
Franceschini, A., Jin, M., Chen, C. W., Silvestri, L., Mastrodonato, A., & Denny, C. A. (2025). Brain-wide immunolabeling and tissue clearing applications for engram research. Neurobiology of Learning and Memory, 218, 108032. https://doi.org/10.1016/j.nlm.2025.108032
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Perkins, S. M., Amematsro, E. A., Cunningham, J., Wang, Q., & Churchland, M. M. (2025). An emerging view of neural geometry in motor cortex supports high-performance decoding. ELife, 12. CLOCKSS. https://doi.org/10.7554/elife.89421
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Corvo, C., Mendez-David, I., Goutal, S., Saba, W., Bottlaender, M., Caillé, F., Hen, R., Colle, R., Corruble, E., Tournier, N., Leroy, C., & David, D. J. (2025). Synaptic Vesicle 2A (SV2A) Positron Emission Tomography (PET) Imaging as a Marker of Therapeutic Response in a Mouse Model of Depression. ACS Pharmacology & Translational Science, 8(2), 339–345. https://doi.org/10.1021/acsptsci.4c00621
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Di Santo, S., Dipoppa, M., Keller, A., Roth, M., Scanziani, M., & Miller, K. D. (2025). Contextual modulation emerges by integrating feedforward and feedback processing in mouse visual cortex. Cell Reports, 44(1), 115088. https://doi.org/10.1016/j.celrep.2024.115088
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Goldberg, A. R., Dovas, A., Torres, D., Pereira, B., Viswanathan, A., Das Sharma, S., Mela, A., Merricks, E. M., Megino-Luque, C., McInvale, J. J., Olabarria, M., Shokooh, L. A., Zhao, H. T., Chen, C., Kotidis, C., Calvaresi, P., Banu, M. A., Razavilar, A., Sudhakar, T. D., … Canoll, P. (2025). Glioma-induced alterations in excitatory neurons are reversed by mTOR inhibition. Neuron. https://doi.org/10.1016/j.neuron.2024.12.026
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Larrea, D., Tamucci, K. A., Kabra, K., Velasco, K. R., Yun, T. D., Pera, M., Montesinos, J., Agrawal, R. R., Paradas, C., Smerdon, J. W., Lowry, E. R., Stepanova, A., Yoval-Sanchez, B., Galkin, A., Wichterle, H., & Area-Gomez, E. (2025). Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS). Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-51578-1
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Rifkin, R. A., Wu, X., Pereira, B., Gill, B. JA., Merricks, E. M., Michalak, A. J., Goldberg, A. R., Humala, N., Dovas, A., Rai, G., McKhann, G. M., Slesinger, P. A., Canoll, P., & Schevon, C. (2025). A selective small-molecule agonist of G protein-gated inwardly-rectifying potassium channels reduces epileptiform activity in mouse models of tumor-associated and provoked seizures. Neuropharmacology, 265, 110259. https://doi.org/10.1016/j.neuropharm.2024.110259
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Xia, F., Fascianelli, V., Vishwakarma, N., Ghinger, F. G., Kwon, A., Gergues, M. M., Lalani, L. K., Fusi, S., & Kheirbek, M. A. (2024). Understanding the neural code of stress to control anhedonia. Nature. https://doi.org/10.1038/s41586-024-08241-y
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Du, A., Flores‐Aguilar, L., Edwards, N. C., Lao, P. J., Ryu, J. K., Akassoglou, K., Wilcock, D. M., Kofler, J., Ikonomovic, M. D., Lai, F., Brickman, A. M., & Head, E. (2024). Increased fibrin deposition in the brains of individuals with Down syndrome and Alzheimer’s disease. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.089882
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Lao, P. J., Edwards, N. C., Flores‐Aguilar, L., Rizvi, B., Smith, A. C., Tudorascu, D., Rosas, H. D., Yassa, M. A., Handen, B. L., Christian, B. T., Gutierrez, J., Wilcock, D. M., Head, E., & Brickman, A. M. (2024). Longitudinal changes in neuroimaging markers of small vessel disease: Implications for clinical trials. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092029
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Lao, P. J., Edwards, N. C., Flores‐Aguilar, L., Rizvi, B., Smith, A. C., Tudorascu, D., Rosas, H. D., Yassa, M. A., Handen, B. L., Christian, B. T., Gutierrez, J., Wilcock, D. M., Head, E., & Brickman, A. M. (2024). Longitudinal changes in neuroimaging markers of small vessel disease: Implications for clinical trials. Alzheimer’s & Dementia, 20(S9). Portico. https://doi.org/10.1002/alz.094386
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Jin, M., Hunsberger, H. C., Whye, A. R., Ogundare, S., Alvarado, N., Sorid, S., Lanio, M., & Denny, C. A. (2024). Investigating the neural ensembles underlying sundowning in an Alzheimer’s disease mouse model. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.089605
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Alshikho, M. J., Morales, C., Pyne, J. D., Amarante, E., Lao, P. J., Turney, I. C., Edwards, N. C., Gu, Y., Manly, J. J., Mayeux, R., & Brickman, A. M. (2024). Characterizing White Matter Hyperintensity (WMH) Patterns with Texture‐Based Analysis. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.091712
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Edwards, N. C., Lao, P. J., Alshikho, M. J., Rizvi, B., Aguilar, L. F., Petersen, M., O’Bryant, S. E., Tudorascu, D., Handen, B. L., Gutierrez, J., Wilcock, D. M., Head, E., & Brickman, A. M. (2024). Independent and interactive contributions of cerebrovascular disease, neuroinflammation, and tau pathophysiology to Alzheimer’s disease‐related diagnostic conversion in adults with Down syndrome. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.087570
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Lippert, R. V., Edwards, N. C., Tosto, G., Pyne, J. D., Lao, P. J., & Brickman, A. M. (2024). Cumulative Incidence Rate Score for Alzheimer’s Disease Risk is Associated with White Matter Hyperintensity Volume in Older Adults Without Dementia. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092734
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Gu, K., Kim, D. K., Kleidermacher, L. E., Berhe, A. D., Sanjurjo, A. D., Leone, R. M., Dreux, S. R., Lin, A. P., Yuan, M., Yang, E., Viswanathan, A., Lorence, I. M., Wang, M., Molyneux, K., Saha, P., & Devlin, M. J. (2024). Operations of a Student-Run Asylum Clinic: Frameworks, Challenges, and Recommendations. Journal of Human Rights Practice, 16(3), 981–994. https://doi.org/10.1093/jhuman/huae015
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Kassraian, P., Bigler, S. K., Gilly Suarez, D. M., Shrotri, N., Barnett, A., Lee, H.-J., Young, W. S., & Siegelbaum, S. A. (2024). The hippocampal CA2 region discriminates social threat from social safety. Nature Neuroscience, 27(11), 2193–2206. https://doi.org/10.1038/s41593-024-01771-8
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Edwards, N. C., Lao, P. J., Alshikho, M. J., Ericsson, O. M., Rizvi, B., Petersen, M. E., O’Bryant, S., Aguilar, L. F., Simoes, S., Mapstone, M., Tudorascu, D. L., Janelidze, S., Hansson, O., Handen, B. L., Christian, B. T., Lee, J. H., Lai, F., Rosas, H. D., Zaman, S., … Brickman, A. M. (2024). Cerebrovascular disease is associated with Alzheimer’s plasma biomarker concentrations in adults with Down syndrome. Brain Communications, 6(5). https://doi.org/10.1093/braincomms/fcae331
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Mastrodonato, A., Jin, M., Kee, N., Lanio, M., Tapia, J., Quintana, L., Muñoz Zamora, A., Deng, S.-X., Xu, X., Landry, D. W., & Denny, C. A. (2024). Prophylactic (R,S)-ketamine and (2S,6S)-hydroxynorketamine Decrease Fear Expression by Differentially Modulating Fear Neural Ensembles. Biological Psychiatry. https://doi.org/10.1016/j.biopsych.2024.09.024
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Wang, W., Williams, D. J., Teoh, J. J., Soundararajan, D., Zuberi, A., Lutz, C. M., Frankel, W. N., & Makinson, C. D. (2024). Impaired axon initial segment structure and function in a model of ARHGEF9 developmental and epileptic encephalopathy. Proceedings of the National Academy of Sciences, 121(42). https://doi.org/10.1073/pnas.2400709121
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Singletary, N. M., Horga, G., & Gottlieb, J. (2024). A neural code supporting prospective probabilistic reasoning for instrumental information demand in humans. Communications Biology, 7(1). https://doi.org/10.1038/s42003-024-06927-7
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Hunsberger, H. C., Lee, S., Jin, M., Lanio, M., Whye, A., Cha, J., Scarlata, M., Matthews, L. C., Jayaseelan, K., & Denny, Christine. A. (2024). Sex-Specific Effects of Anxiety on Cognition and Activity-Dependent Neural Networks: Insights from (Female) Mice and (Wo)Men. Biological Psychiatry. https://doi.org/10.1016/j.biopsych.2024.09.016
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Vandebergh, M., Ramos, E. M., Corriveau-Lecavalier, N., Ramanan, V. K., Kornak, J., Mester, C., Kolander, T., Brushaber, D. E., Staffaroni, A. M., Geschwind, D. H., Wolf, A. A., Kantarci, K., Gendron, T., Petrucelli, L., Van den Broeck, M., Wynants, S., Baker, M., Borrego-Écija, S., … Appleby, B. (2024). Gene-Specific Effects on Brain Volume and Cognition of TMEM106B in Frontotemporal Lobar Degeneration. Neurology, 103(8). https://doi.org/10.1212/wnl.0000000000209832
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Saeki, K., Pan, R., Lee, E., Kurotaki, D., & Ozato, K. (2024). IRF8 defines the epigenetic landscape in postnatal microglia, thereby directing their transcriptome programs. Nature Immunology, 25(10), 1928–1942. https://doi.org/10.1038/s41590-024-01962-2
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Burke, M. R., Sotiropoulos, I., & Waites, C. L. (2024). The multiple roles of chronic stress and glucocorticoids in Alzheimer’s disease pathogenesis. Trends in Neurosciences, 47(11), 933–948. https://doi.org/10.1016/j.tins.2024.08.015
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Randolph, L. K., Pauers, M. M., Martínez, J. C., Sibener, L. J., Zrzavy, M. A., Sharif, N. A., Gonzalez, T. M., Ramachandran, K. V., Dominguez, D., & Hengst, U. (2024). Regulation of synapse density by Pumilio RNA-binding proteins. Cell Reports, 43(10), 114747. https://doi.org/10.1016/j.celrep.2024.114747
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Yang, H. H., Brezovec, B. E., Serratosa Capdevila, L., Vanderbeck, Q. X., Adachi, A., Mann, R. S., & Wilson, R. I. (2024). Fine-grained descending control of steering in walking Drosophila. Cell, 187(22), 6290-6308.e27. https://doi.org/10.1016/j.cell.2024.08.033
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Shahriar, S., Biswas, S., Zhao, K., Akcan, U., Tuohy, M. C., Glendinning, M. D., Kurt, A., Wayne, C. R., Prochilo, G., Price, M. Z., Stuhlmann, H., Brekken, R. A., Menon, V., & Agalliu, D. (2024). VEGF-A-mediated venous endothelial cell proliferation results in neoangiogenesis during neuroinflammation. Nature Neuroscience, 27(10), 1904–1917. https://doi.org/10.1038/s41593-024-01746-9
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Banu, M. A., Dovas, A., Argenziano, M. G., Zhao, W., Sperring, C. P., Cuervo Grajal, H., Liu, Z., Higgins, D. M., Amini, M., Pereira, B., Ye, L. F., Mahajan, A., Humala, N., Furnari, J. L., Upadhyayula, P. S., Zandkarimi, F., Nguyen, T. T., Teasley, D., Wu, P. B., … Canoll, P. (2024). A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma. The EMBO Journal. https://doi.org/10.1038/s44318-024-00176-4
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Courellis, H. S., Minxha, J., Cardenas, A. R., Kimmel, D. L., Reed, C. M., Valiante, T. A., Salzman, C. D., Mamelak, A. N., Fusi, S., & Rutishauser, U. (2024). Abstract representations emerge in human hippocampal neurons during inference. Nature, 632(8026), 841–849. https://doi.org/10.1038/s41586-024-07799-x
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Utkina-Sosunova, I., Chiorazzi, A., de Planell-Saguer, M., Li, H., Meregalli, C., Pozzi, E., Carozzi, V. A., Canta, A., Monza, L., Alberti, P., Fumagalli, G., Karan, C., Moayedi, Y., Przedborski, S., Cavaletti, G., & Lotti, F. (2024). Molsidomine provides neuroprotection against vincristine-induced peripheral neurotoxicity through soluble guanylyl cyclase activation. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-70294-w
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Fascianelli, V., Battista, A., Stefanini, F., Tsujimoto, S., Genovesio, A., & Fusi, S. (2024). Neural representational geometries reflect behavioral differences in monkeys and recurrent neural networks. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-50503-w
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Adilbay, D., Gonzales, J., Zazhytska, M., Demetrio de Souza Franca, P., Roberts, S., Viray, T. D., Artschwager, R., Patel, S., Kodra, A., Overdevest, J. B., Chow, C. Y., King, G. F., Jain, S. K., Ordonez, A. A., Carroll, L. S., Lomvardas, S., Reiner, T., & Pillarsetty, N. (2024). Noninvasive Diagnostic Method to Objectively Measure Olfaction and Diagnose Smell Disorders by a Molecularly Targeted Fluorescence Imaging Agent. Journal of Nuclear Medicine, 65(8), 1293–1300. https://doi.org/10.2967/jnumed.123.266123
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Liao, Z., Gonzalez, K. C., Li, D. M., Yang, C. M., Holder, D., McClain, N. E., Zhang, G., Evans, S. W., Chavarha, M., Simko, J., Makinson, C. D., Lin, M. Z., Losonczy, A., & Negrean, A. (2024). Functional architecture of intracellular oscillations in hippocampal dendrites. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-50546-z
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Kloske, C. M., Belloy, M. E., Blue, E. E., Bowman, G. R., Carrillo, M. C., Chen, X., Chiba‐Falek, O., Davis, A. A., Paolo, G. D., Garretti, F., Gate, D., Golden, L. R., Heinecke, J. W., Herz, J., Huang, Y., Iadecola, C., Johnson, L. A., Kanekiyo, T., Karch, C. M., … Holtzman, D. M. (2024). Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.13877
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Elleman, A. V., Milicic, N., Williams, D. J., Simko, J., Liu, C. J., Haynes, A. L., Ehrlich, D. E., Makinson, C. D., & Du Bois, J. (2024). Behavioral control through the direct, focal silencing of neuronal activity. Cell Chemical Biology, 31(7), 1324-1335.e20. https://doi.org/10.1016/j.chembiol.2024.04.003
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Lippl, S., Kay, K., Jensen, G., Ferrera, V. P., & Abbott, L. F. (2024). A mathematical theory of relational generalization in transitive inference. Proceedings of the National Academy of Sciences, 121(28). https://doi.org/10.1073/pnas.2314511121
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Orsini, F., Bosica, M., Martucci, A., De Paola, M., Comolli, D., Pascente, R., Forloni, G., Fraser, P. E., Arancio, O., & Fioriti, L. (2024). SARS-CoV-2 Nucleocapsid Protein Induces Tau Pathological Changes That Can Be Counteracted by SUMO2. International Journal of Molecular Sciences, 25(13), 7169. https://doi.org/10.3390/ijms25137169
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Rizvi, B., Lao, P. J., Sathishkumar, M., Taylor, L., Queder, N., McMillan, L., Edwards, N. C., Keator, D. B., Doran, E., Hom, C., Nguyen, D., Rosas, H. D., Lai, F., Schupf, N., Gutierrez, J., Silverman, W., Lott, I. T., Mapstone, M., Wilcock, D. M., … Brickman, A. M. (2024). A pathway linking pulse pressure to dementia in adults with Down syndrome. Brain Communications, 6(3). https://doi.org/10.1093/braincomms/fcae157
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Demaestri, C., Pisciotta, M., Altunkeser, N., Berry, G., Hyland, H., Breton, J., Darling, A., Williams, B., & Bath, K. G. (2024). Central amygdala CRF+ neurons promote heightened threat reactivity following early life adversity in mice. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-49828-3
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Kumar, A., Larrea, D., Pero, M. E., Infante, P., Conenna, M., Shin, G. J., Van Elias, V., Grueber, W. B., Di Marcotullio, L., Area-Gomez, E., & Bartolini, F. (2024). MFN2 coordinates mitochondria motility with α-tubulin acetylation and this regulation is disrupted in CMT2A. IScience, 27(6), 109994. https://doi.org/10.1016/j.isci.2024.109994
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Buss, E. W., Jiang, Y.-Q., Santoro, B., Brann, D. H., Nicholson, D. A., Siegelbaum, S. A., & Sun, Q. (2024). Regulation by Presynaptic NMDA Receptors of Non-Linear Postsynaptic Summation of the Cortical Input to CA1 Pyramidal Neurons. Neuroscience. https://doi.org/10.1016/j.neuroscience.2024.06.005
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Suryadevara, V., Hudgins, A. D., Rajesh, A., Pappalardo, A., Karpova, A., Dey, A. K., Hertzel, A., Agudelo, A., Rocha, A., Soygur, B., Schilling, B., Carver, C. M., Aguayo-Mazzucato, C., Baker, D. J., Bernlohr, D. A., Jurk, D., Mangarova, D. B., Quardokus, E. M., Enninga, E. A. L., … Neretti, N. (2024). SenNet recommendations for detecting senescent cells in different tissues. Nature Reviews Molecular Cell Biology. https://doi.org/10.1038/s41580-024-00738-8
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Holt, C. J., Miller, K. D., & Ahmadian, Y. (2024). The stabilized supralinear network accounts for the contrast dependence of visual cortical gamma oscillations. PLOS Computational Biology, 20(6), e1012190. https://doi.org/10.1371/journal.pcbi.1012190
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