A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma

Banu, M. A., Dovas, A., Argenziano, M. G., Zhao, W., Sperring, C. P., Cuervo Grajal, H., Liu, Z., Higgins, D. M., Amini, M., Pereira, B., Ye, L. F., Mahajan, A., Humala, N., Furnari, J. L., Upadhyayula, P. S., Zandkarimi, F., Nguyen, T. T., Teasley, D., Wu, P. B., … Canoll, P. (2024). A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma. The EMBO Journal. https://doi.org/10.1038/s44318-024-00176-4
Authors:
Matei A. Banu
Athanassios Dovas
Michael Argenziano
Wenting Zhao
Colin P. Sperring
Henar Cuervo
Zhouzerui Liu
Dominique Higgins
Misha Amini
Brianna Pereira
Ling F. Ye
Aayushi Mahajan
Nelson Humala
Julia Furnari
Pavan S. Upadhyayula
Fereshteh Zandkarimi
Trang Nguyen
Damian Teasley
Peter Wu
Hai Li
Charles Karan
Tyrone Dowdy
Aida Razavilar
Markus D. Siegelin
Jan Kitajewski
Mioara Larion
Jeffrey N. Bruce
Brent R. Stockwell
Peter A. Sims
Peter Canoll
Affiliated Authors:
Matei A. Banu
Athanassios Dovas
Michael Argenziano
Wenting Zhao
Colin P. Sperring
Zhouzerui Liu
Misha Amini
Brianna Pereira
Ling F. Ye
Aayushi Mahajan
Nelson Humala
Julia Furnari
Pavan S. Upadhyayula
Fereshteh Zandkarimi
Trang Nguyen
Damian Teasley
Hai Li
Charles Karan
Aida Razavilar
Markus D. Siegelin
Jeffrey N. Bruce
Brent R. Stockwell
Peter A. Sims
Peter Canoll
Columbia Affiliation:
Subjects:
Mechanisms and Implications of Ferroptosis in Cancer (OpenAlex Topic)
Role of Long Noncoding RNAs in Cancer and Development (OpenAlex Topic)
Regulation of RNA Processing and Function (OpenAlex Topic)
Author Keywords:
astrocytic
ferroptosis
glioma
mitochondrial-metabolism
quiescent
elink
Publication Type:
Article
Unique ID:
10.1038/s44318-024-00176-4
PMID:
39192032
DOI:
10.1038/s44318-024-00176-4
Journal:
EMBO Journal
Publication Date:
Data Source:
OpenAlex
Source Link:
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Record Created: