Department of Neuroscience

Displaying 101 - 150 of 177CSV
Colombo, S., Reddy, H. P., Petri, S., Williams, D. J., Shalomov, B., Dhindsa, R. S., Gelfman, S., Krizay, D., Bera, A. K., Yang, M., Peng, Y., Makinson, C. D., Boland, M. J., Frankel, W. N., Goldstein, D. B., & Dascal, N. (2023). Epilepsy in a mouse model of GNB1 encephalopathy arises from altered potassium (GIRK) channel signaling and is alleviated by a GIRK inhibitor. Frontiers in Cellular Neuroscience, 17. https://doi.org/10.3389/fncel.2023.1175895
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Ong, H. W., Liang, Y., Richardson, W., Lowry, E. R., Wells, C. I., Chen, X., Silvestre, M., Dempster, K., Silvaroli, J. A., Smith, J. L., Wichterle, H., Pabla, N. S., Ultanir, S. K., Bullock, A. N., Drewry, D. H., & Axtman, A. D. (2023). Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS Chemical Neuroscience, 14(9), 1672–1685. https://doi.org/10.1021/acschemneuro.3c00135
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Pilaz, L.-J., Liu, J., Joshi, K., Tsunekawa, Y., Musso, C. M., D’Arcy, B. R., Suzuki, I. K., Alsina, F. C., KC, P., Sethi, S., Vanderhaeghen, P., Polleux, F., & Silver, D. L. (2023). Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development. Neuron, 111(6), 839-856.e5. https://doi.org/10.1016/j.neuron.2023.02.023
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Galindo, S. E., Wood, A. J., Cooney, P. C., Hammond, L. A., & Grueber, W. B. (2023). Axon–axon interactions determine modality-specific wiring and subcellular synaptic specificity in a somatosensory circuit. Development, 150(5). https://doi.org/10.1242/dev.199832
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Paquelet, G. E., Carrion, K., Lacefield, C. O., Zhou, P., Hen, R., & Miller, B. R. (2023). Protocol for in vivo imaging and analysis of brainstem neuronal activity in the dorsal raphe nucleus of freely behaving mice. STAR Protocols, 4(1), 102074. https://doi.org/10.1016/j.xpro.2023.102074
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Shashaank, N., Somayaji, M., Miotto, M., Mosharov, E. V., Makowicz, E. A., Knowles, D. A., Ruocco, G., & Sulzer, D. L. (2023). Computational models of dopamine release measured by fast scan cyclic voltammetry in vivo. PNAS Nexus, 2(3). https://doi.org/10.1093/pnasnexus/pgad044
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Ford, L., Asok, A., Tripp, A. D., Parro, C., Fitzpatrick, M., de Solis, C. A., Chen, P.-T. Y., Shafiian, N., Fioriti, L., Soni, R. K., & Kandel, E. R. (2023). CPEB3 low-complexity motif regulates local protein synthesis via protein–protein interactions in neuronal ribonucleoprotein granules. Proceedings of the National Academy of Sciences, 120(6). https://doi.org/10.1073/pnas.2114747120
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Qian, N., Goldberg, M. E., & Zhang, M. (2023). Tuning curves vs. population responses, and perceptual consequences of receptive-field remapping. Frontiers in Computational Neuroscience, 16. https://doi.org/10.3389/fncom.2022.1060757
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Barack, D. L., Bakkour, A., Shohamy, D., & Salzman, C. D. (2023). Visuospatial information foraging describes search behavior in learning latent environmental features. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-27662-9
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He, H., Ahsan, A., Bera, R., McLain, N., Faulkner, R., Ramachandran, K. V., Margolis, S. S., & Cline, H. T. (2023). Neuronal membrane proteasomes regulate neuronal circuit activity in vivo and are required for learning-induced behavioral plasticity. Proceedings of the National Academy of Sciences, 120(3). https://doi.org/10.1073/pnas.2216537120
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Slavi, N., Balasubramanian, R., Lee, M. A., Liapin, M., Oaks-Leaf, R., Peregrin, J., Potenski, A., Troy, C. M., Ross, M. E., Herrera, E., Kosmidis, S., John, S. W. M., & Mason, C. A. (2023). CyclinD2-mediated regulation of neurogenic output from the retinal ciliary margin is perturbed in albinism. Neuron, 111(1), 49-64.e5. https://doi.org/10.1016/j.neuron.2022.10.025
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Qvist, J. S., Scherma, M., Jayaram-Lindström, N., Fratta, W., Kandel, D. B., Kandel, E. R., Fadda, P., & Melas, P. A. (2022). Synaptoproteomic Analysis of the Prefrontal Cortex Reveals Spatio-Temporal Changes in SYNGAP1 Following Cannabinoid Exposure in Rat Adolescence. International Journal of Molecular Sciences, 24(1), 698. https://doi.org/10.3390/ijms24010698
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Castela, I., Casado-Polanco, R., Rubio, Y. V.-W., da Silva, J. A., Marquez, R., Pro, B., Moratalla, R., Redgrave, P., Costa, R. M., Obeso, J., & Hernandez, L. F. (2023). Selective activation of striatal indirect pathway suppresses levodopa induced-dyskinesias. Neurobiology of Disease, 176, 105930. https://doi.org/10.1016/j.nbd.2022.105930
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Carazo-Arias, E., Nguyen, P. T., Kass, M., Jee, H. J., Nautiyal, K. M., Magalong, V., Coie, L., Andreu, V., Gergues, M. M., Khalil, H., Akil, H., Arcego, D. M., Meaney, M., Anacker, C., Samuels, B. A., Pintar, J. E., Morozova, I., Kalachikov, S., & Hen, R. (2022). Contribution of the Opioid System to the Antidepressant Effects of Fluoxetine. Biological Psychiatry, 92(12), 952–963. https://doi.org/10.1016/j.biopsych.2022.05.030
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Kalmbach, A., Winiger, V., Jeong, N., Asok, A., Gallistel, C. R., Balsam, P. D., & Simpson, E. H. (2022). Dopamine encodes real-time reward availability and transitions between reward availability states on different timescales. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31377-2
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Rabadan, M. A., De La Cruz, E. D., Rao, S. B., Chen, Y., Gong, C., Crabtree, G., Xu, B., Markx, S., Gogos, J. A., Yuste, R., & Tomer, R. (2022). An in vitro model of neuronal ensembles. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31073-1
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Ashinoff, B. K., Buck, J., Woodford, M., & Horga, G. (2022). The effects of base rate neglect on sequential belief updating and real-world beliefs. PLOS Computational Biology, 18(12), e1010796. https://doi.org/10.1371/journal.pcbi.1010796
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Teng, S., Zhen, F., Wang, L., Schalchli, J. C., Simko, J., Chen, X., Jin, H., Makinson, C. D., & Peng, Y. (2022). Control of non-REM sleep by ventrolateral medulla glutamatergic neurons projecting to the preoptic area. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32461-3
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Avisar, H., Guardia-Laguarta, C., Surface, M., Papagiannakis, N., Maniati, M., Antonellou, R., Papadimitriou, D., Koros, C., Athanassiadou, A., Przedborski, S., Lerner, B., Stefanis, L., Area-Gomez, E., & Alcalay, R. N. (2022). Lipid level alteration in human and cellular models of alpha synuclein mutations. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00313-y
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Patel, T., Hammelman, J., Aziz, S., Jang, S., Closser, M., Michaels, T. L., Blum, J. A., Gifford, D. K., & Wichterle, H. (2022). Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-33022-4
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Lee, A., Kondapalli, C., Virga, D. M., Lewis, T. L., Koo, S. Y., Ashok, A., Mairet-Coello, G., Herzig, S., Foretz, M., Viollet, B., Shaw, R., Sproul, A., & Polleux, F. (2022). Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32130-5
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Spinazzi, E. F., Argenziano, M. G., Upadhyayula, P. S., Banu, M. A., Neira, J. A., Higgins, D. M. O., Wu, P. B., Pereira, B., Mahajan, A., Humala, N., Al-Dalahmah, O., Zhao, W., Save, A. V., Gill, B. J. A., Boyett, D. M., Marie, T., Furnari, J. L., Sudhakar, T. D., Stopka, S. A., … Bruce, J. N. (2022). Chronic convection-enhanced delivery of topotecan for patients with recurrent glioblastoma: a first-in-patient, single-centre, single-arm, phase 1b trial. The Lancet Oncology, 23(11), 1409–1418. https://doi.org/10.1016/s1470-2045(22)00599-x
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Rayan, N. A., Kumar, V., Aow, J., Rastegar, N., Lim, M. G. L., O’Toole, N., Aliwarga, E., Arcego, D. M., Yeo, H. T. G., Wong, J. Y., Lee, M. Y., Schmidt, F., Haja, H. S., Tam, W. L., Zhang, T.-Y., Diorio, J., Anacker, C., Hen, R., Parent, C., … Prabhakar, S. (2022). Integrative multi-omics landscape of fluoxetine action across 27 brain regions reveals global increase in energy metabolism and region-specific chromatin remodelling. Molecular Psychiatry, 27(11), 4510–4525. https://doi.org/10.1038/s41380-022-01725-1
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Marshall, N. J., Glaser, J. I., Trautmann, E. M., Amematsro, E. A., Perkins, S. M., Shadlen, M. N., Abbott, L. F., Cunningham, J. P., & Churchland, M. M. (2022). Flexible neural control of motor units. Nature Neuroscience, 25(11), 1492–1504. https://doi.org/10.1038/s41593-022-01165-8
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Qian, N., Lipkin, R. M., Kaszowska, A., Silipo, G., Dias, E. C., Butler, P. D., & Javitt, D. C. (2022). Computational modeling of excitatory/inhibitory balance impairments in schizophrenia. Schizophrenia Research, 249, 47–55. https://doi.org/10.1016/j.schres.2020.03.027
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Hewitt, V. L., Miller-Fleming, L., Twyning, M. J., Andreazza, S., Mattedi, F., Prudent, J., Polleux, F., Vagnoni, A., & Whitworth, A. J. (2022). Decreasing pdzd8-mediated mito–ER contacts improves organismal fitness and mitigates Aβ42toxicity. Life Science Alliance, 5(11), e202201531. https://doi.org/10.26508/lsa.202201531
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Li, M., Tan, H.-E., Lu, Z., Tsang, K. S., Chung, A. J., & Zuker, C. S. (2022). Gut–brain circuits for fat preference. Nature, 610(7933), 722–730. https://doi.org/10.1038/s41586-022-05266-z
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Shayya, H. J., Kahiapo, J. K., Duffié, R., Lehmann, K. S., Bashkirova, L., Monahan, K., Dalton, R. P., Gao, J., Jiao, S., Schieren, I., Belluscio, L., & Lomvardas, S. (2022). ER stress transforms random olfactory receptor choice into axon targeting precision. Cell, 185(21), 3896-3912.e22. https://doi.org/10.1016/j.cell.2022.08.025
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Whitebirch, A. C., LaFrancois, J. J., Jain, S., Leary, P., Santoro, B., Siegelbaum, S. A., & Scharfman, H. E. (2022). Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy. Neuron, 110(19), 3121-3138.e8. https://doi.org/10.1016/j.neuron.2022.07.020
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Birdsall, V., Kirwan, K., Zhu, M., Imoto, Y., Wilson, S. M., Watanabe, S., & Waites, C. L. (2022). Axonal transport of Hrs is activity dependent and facilitates synaptic vesicle protein degradation. Life Science Alliance, 5(10), e202000745. https://doi.org/10.26508/lsa.202000745
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Zilcha‐Mano, S., Zhu, X., Lazarov, A., Suarez‐Jimenez, B., Helpman, L., Kim, Y., Maitlin, C., Neria, Y., & Rutherford, B. R. (2022). Structural brain features signaling trauma, PTSD, or resilience? A systematic exploration. Depression and Anxiety, 39(10–11), 695–705. Portico. https://doi.org/10.1002/da.23275
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Shih, H.-J. S., Macpherson, C. E., King, M., Delaney, E., Gu, Y., Long, K., Reid, J., Fineman, J., Yu, G., Rieger, J., Satchidanand, A., Shah, H., Alcalay, R. N., & Quinn, L. (2022). Physical Activity Coaching via Telehealth for People With Parkinson Disease: A Cohort Study. Journal of Neurologic Physical Therapy, 46(4), 240–250. https://doi.org/10.1097/npt.0000000000000410
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Frere, J. J., Serafini, R. A., Pryce, K. D., Zazhytska, M., Oishi, K., Golynker, I., Panis, M., Zimering, J., Horiuchi, S., Hoagland, D. A., Møller, R., Ruiz, A., Kodra, A., Overdevest, J. B., Canoll, P. D., Borczuk, A. C., Chandar, V., Bram, Y., Schwartz, R., … tenOever, B. R. (2022). SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery. Science Translational Medicine, 14(664). https://doi.org/10.1126/scitranslmed.abq3059
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Abe, T., Kinsella, I., Saxena, S., Buchanan, E. K., Couto, J., Briggs, J., Kitt, S. L., Glassman, R., Zhou, J., Paninski, L., & Cunningham, J. P. (2022). Neuroscience Cloud Analysis As a Service: An open-source platform for scalable, reproducible data analysis. Neuron, 110(17), 2771-2789.e7. https://doi.org/10.1016/j.neuron.2022.06.018
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Mishra, R., Phan, T., Kumar, P., Morrissey, Z., Gupta, M., Hollands, C., Shetti, A., Lopez, K. L., Maienschein-Cline, M., Suh, H., Hen, R., & Lazarov, O. (2022). Augmenting neurogenesis rescues memory impairments in Alzheimer’s disease by restoring the memory-storing neurons. Journal of Experimental Medicine, 219(9). https://doi.org/10.1084/jem.20220391
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Paquelet, G. E., Carrion, K., Lacefield, C. O., Zhou, P., Hen, R., & Miller, B. R. (2022). Single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors. Neuron, 110(16), 2664-2679.e8. https://doi.org/10.1016/j.neuron.2022.05.015
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Xu, P., Shimomura, K., Lee, C., Gao, X., Simpson, E. H., Huang, G., Joseph, C. M., Kumar, V., Ge, W.-P., Pawlowski, K. S., Frye, M. D., Kourrich, S., Kandel, E. R., & Takahashi, J. S. (2022). A missense mutation in Kcnc3 causes hippocampal learning deficits in mice. Proceedings of the National Academy of Sciences, 119(31). https://doi.org/10.1073/pnas.2204901119
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Li, L., Wyler, S. C., León-Mercado, L. A., Xu, B., Oh, Y., Swati, Chen, X., Wan, R., Arnold, A. G., Jia, L., Wang, G., Nautiyal, K., Hen, R., Sohn, J.-W., & Liu, C. (2022). Delineating a serotonin 1B receptor circuit for appetite suppression in mice. Journal of Experimental Medicine, 219(8). https://doi.org/10.1084/jem.20212307
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Stujenske, J. M., O’Neill, P.-K., Fernandes-Henriques, C., Nahmoud, I., Goldburg, S. R., Singh, A., Diaz, L., Labkovich, M., Hardin, W., Bolkan, S. S., Reardon, T. R., Spellman, T. J., Salzman, C. D., Gordon, J. A., Liston, C., & Likhtik, E. (2022). Prelimbic cortex drives discrimination of non-aversion via amygdala somatostatin interneurons. Neuron, 110(14), 2258-2267.e11. https://doi.org/10.1016/j.neuron.2022.03.020
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Martyniuk, K. M., Torres-Herraez, A., Lowes, D. C., Rubinstein, M., Labouesse, M. A., & Kellendonk, C. (2022). Dopamine D2Rs coordinate cue-evoked changes in striatal acetylcholine levels. ELife, 11. CLOCKSS. https://doi.org/10.7554/elife.76111
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Pérez-Torres, E. J., Utkina-Sosunova, I., Mishra, V., Barbuti, P., De Planell-Saguer, M., Dermentzaki, G., Geiger, H., Basile, A. O., Robine, N., Fagegaltier, D., Politi, K. A., Rinchetti, P., Jackson-Lewis, V., Harms, M., Phatnani, H., Lotti, F., Przedborski, S., Phatnani, H., … Traynor, B. J. (2022). Retromer dysfunction in amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences, 119(26). https://doi.org/10.1073/pnas.2118755119
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Kenchappa, R. S., Dovas, A., Argenziano, M. G., Meyer, C. T., Stopfer, L. E., Banu, M. A., Pereira, B., Griffith, J., Mohammad, A., Talele, S., Haddock, A., Zarco, N., Elmquist, W., White, F., Quaranta, V., Sims, P., Canoll, P., & Rosenfeld, S. S. (2022). Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma. Cell Reports, 39(12), 110991. https://doi.org/10.1016/j.celrep.2022.110991
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Han, J., Andreu, V., Langreck, C., Pekarskaya, E. A., Grinnell, S. G., Allain, F., Magalong, V., Pintar, J., Kieffer, B. L., Harris, A. Z., Javitch, J. A., Hen, R., & Nautiyal, K. M. (2021). Mu opioid receptors on hippocampal GABAergic interneurons are critical for the antidepressant effects of tianeptine. Neuropsychopharmacology, 47(7), 1387–1397. https://doi.org/10.1038/s41386-021-01192-2
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