Center for Translational Immunology

Displaying 51 - 100 of 149CSV
Rudchenko, S., Taylor, S., Milosavic, N., Rudchenko, M., Wedderhoff Tissi, B., Mapara, M. Y., & Stojanovic, M. N. (2023). Amplification of Signal on Cell Surfaces in Molecular Cascades. Cells, 12(24), 2858. https://doi.org/10.3390/cells12242858
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Melms, J. C., Ho, P., Rogava, M., & Izar, B. (2023). From patient tissue correlates to molecular mechanisms of cancer immune evasion: the emerging role of CD58 and PD-L1 co-regulation via CMTM6. Genes & Immunity, 25(1), 82–84. https://doi.org/10.1038/s41435-023-00224-9
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Hong, J. S., Shamim, A., Atta, H., Nonnecke, E. B., Merl, S., Patwardhan, S., Manell, E., Gunes, E., Jordache, P., Chen, B., Lu, W., Shen, B., Dionigi, B., Kiran, R. P., Sykes, M., Zorn, E., Bevins, C. L., & Weiner, J. (2024). Application of enzyme-linked immunosorbent assay to detect antimicrobial peptides in human intestinal lumen. Journal of Immunological Methods, 525, 113599. https://doi.org/10.1016/j.jim.2023.113599
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Lee, S., Ahn, J., Kim, S.-M., Kim, D., Yeom, J., Kim, J., Park, J. Y., & Ryu, B.-Y. (2023). Fluid dynamic design for mitigating undesired cell effects and its application to testis cell response testing to endocrine disruptors. Journal of Biological Engineering, 17(1). https://doi.org/10.1186/s13036-023-00369-1
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Ahn, J., Hwang, I.-S., Park, M.-R., Hwang, S., & Lee, K. (2023). Imprinting at the KBTBD6 locus involves species-specific maternal methylation and monoallelic expression in livestock animals. Journal of Animal Science and Biotechnology, 14(1). https://doi.org/10.1186/s40104-023-00931-3
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Fu, J., Li, S., Ma, H., Yang, J., Pagnotti, G. M., Brown, L. M., Weiss, S. J., Mapara, M. Y., & Lentzsch, S. (2023). The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-39769-8
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Khatiwada, P., Soni, M., & Muranski, P. (2023). Highly Active Cytotoxic CD4 + T Cells Targeting EBV Oncoproteins with Enhanced In Vivo Anti-Tumor and Self-Renewal Properties. Blood, 142(Supplement 1), 3464–3464. https://doi.org/10.1182/blood-2023-190690
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Wang, X. K., Uzuni, A., Belay, K., Harle, D. W., Gordillo, C. A., Macedo, R. J., Chakrabarti, S., Shi, L., Pressler, M., Fuller, J., Azizi, E., & Reshef, R. (2023). Characteristics of Alloreactive T-Cell Clones That Predict Early Development of Acute GvHD Following Allogeneic HCT. Blood, 142(Supplement 1), 2042–2042. https://doi.org/10.1182/blood-2023-187932
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Hawley, J. E., Obradovic, A. Z., Dallos, M. C., Lim, E. A., Runcie, K., Ager, C. R., McKiernan, J., Anderson, C. B., Decastro, G. J., Weintraub, J., Virk, R., Lowy, I., Hu, J., Chaimowitz, M. G., Guo, X. V., Zhang, Y., Haffner, M. C., Worley, J., Stein, M. N., … Drake, C. G. (2023). Anti-PD-1 immunotherapy with androgen deprivation therapy induces robust immune infiltration in metastatic castration-sensitive prostate cancer. Cancer Cell, 41(11), 1972-1988.e5. https://doi.org/10.1016/j.ccell.2023.10.006
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Gu, H. J., Ahn, J. S., Ahn, G. J., Shin, S. H., & Ryu, B.-Y. (2023). Restoration of PM2.5-induced spermatogonia GC-1 cellular damage by parthenolide via suppression of autophagy and inflammation: An in vitro study. Toxicology, 499, 153651. https://doi.org/10.1016/j.tox.2023.153651
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Soni, M. K., Migliori, E., Fu, J., Assal, A., Chan, H. T., Pan, J., Khatiwada, P., Ciubotariu, R., May, M. S., Pereira, M. R., De Giorgi, V., Sykes, M., Mapara, M. Y., & Muranski, P. J. (2023). The prospect of universal coronavirus immunity: characterization of reciprocal and non-reciprocal T cell responses against SARS-CoV2 and common human coronaviruses. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1212203
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Tran, L. M., Macedo, C., Zahorchak, A. F., Gu, X., Elinoff, B., Singhi, A. D., Isett, B., Zeevi, A., Sykes, M., Breen, K., Srivastava, A., Ables, E. M., Landsittel, D., Styn, M. A., Humar, A., Lakkis, F. G., Metes, D. M., & Thomson, A. W. (2023). Donor-derived regulatory dendritic cell infusion modulates effector CD8 + T cell and NK cell responses after liver transplantation. Science Translational Medicine, 15(717). https://doi.org/10.1126/scitranslmed.adf4287
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Cordero, H., Hess, J., Nitschki, E., Kanshin, E., Roy, P., Shihab, R., Kalfa, D. M., Bacha, E. A., Ueberheide, B., & Zorn, E. (2023). Antibody responses to dietary antigens are accompanied by specific plasma cells in the infant thymus. Journal of Allergy and Clinical Immunology, 152(4), 1010–1018. https://doi.org/10.1016/j.jaci.2023.06.018
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Zhang, X., Tyrrell, D. J., Alliston, T., Schilling, B., Yousefzadeh, M. J., & Schafer, M. J. (2023). Senescence and Inflammation: Summary of a Gerontological Society of America and National Institute on Aging-Sponsored Symposium. The Journals of Gerontology: Series A, 78(10), 1733–1739. https://doi.org/10.1093/gerona/glad120
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Ager, C. R., Zhang, M., Chaimowitz, M., Bansal, S., Tagore, S., Obradovic, A., Jugler, C., Rogava, M., Melms, J. C., McCann, P., Spina, C., Drake, C. G., Dallos, M. C., & Izar, B. (2023). KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response. Journal for ImmunoTherapy of Cancer, 11(9), e006782. https://doi.org/10.1136/jitc-2023-006782
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Zhai, N., Liu, W., Jin, C.-H., Ding, Y., Sun, L., Zhang, D., Wang, Z., Tang, Y., Zhao, W., LeGuern, C., Mapara, M. Y., Wang, H., & Yang, Y.-G. (2023). Lack of IFN-γ Receptor Signaling Inhibits Graft-versus-Host Disease by Potentiating Regulatory T Cell Expansion and Conversion. The Journal of Immunology, 211(5), 885–894. https://doi.org/10.4049/jimmunol.2200411
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Nguyen, S. N., Vinogradsky, A. V., Ferrari, G., Sykes, M., Bacha, E. A., Richmond, M. E., & Goldstone, A. B. (2023). Pitfalls and Future Directions of Contemporary Pediatric Valve Surgery: the Case for Living Valve Substitutes. Current Pediatrics Reports, 11(4), 180–192. https://doi.org/10.1007/s40124-023-00295-2
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Akahoshi, Y., Spyrou, N., Hogan, W. J., Ayuk, F., DeFilipp, Z., Weber, D., Choe, H. K., Hexner, E. O., Rösler, W., Etra, A. M., Sandhu, K., Yanik, G. A., Chanswangphuwana, C., Kitko, C. L., Reshef, R., Kraus, S., Wölfl, M., Eder, M., Bertrand, H., … Chen, Y.-B. (2023). Incidence, clinical presentation, risk factors, outcomes, and biomarkers in de novo late acute GVHD. Blood Advances, 7(16), 4479–4491. https://doi.org/10.1182/bloodadvances.2023009885
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Moazami, N., Stern, J. M., Khalil, K., Kim, J. I., Narula, N., Mangiola, M., Weldon, E. P., Kagermazova, L., James, L., Lawson, N., Piper, G. L., Sommer, P. M., Reyentovich, A., Bamira, D., Saraon, T., Kadosh, B. S., DiVita, M., Goldberg, R. I., Hussain, S. T., … Montgomery, R. A. (2023). Pig-to-human heart xenotransplantation in two recently deceased human recipients. Nature Medicine, 29(8), 1989–1997. https://doi.org/10.1038/s41591-023-02471-9
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Amancherla, K., Schlendorf, K. H., Vlasschaert, C., Lowery, B. D., Wells, Q. S., See, S. B., Zorn, E., Colombo, P. C., Reilly, M. P., Lindenfeld, J., Uriel, N., Freedman, J. E., Shah, R. V., Moslehi, J., Bick, A. G., & Clerkin, K. (2023). Clonal hematopoiesis of indeterminate potential and outcomes after heart transplantation: A multicenter study. American Journal of Transplantation, 23(8), 1256–1263. https://doi.org/10.1016/j.ajt.2023.04.028
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Kornberg, A., Botella, T., Moon, C. S., Rao, S., Gelbs, J., Cheng, L., Miller, J., Bacarella, A. M., García-Vilas, J. A., Vargas, J., Yu, X., Krupska, I., Bush, E., Garcia-Carrasquillo, R., Lebwohl, B., Krishnareddy, S., Lewis, S., Green, P. H. R., Bhagat, G., … Han, A. (2023). Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease. Science Immunology, 8(85). https://doi.org/10.1126/sciimmunol.adf4312
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Ho, P., Melms, J. C., Rogava, M., Frangieh, C. J., Poźniak, J., Shah, S. B., Walsh, Z., Kyrysyuk, O., Amin, A. D., Caprio, L., Fullerton, B. T., Soni, R. K., Ager, C. R., Biermann, J., Wang, Y., Khosravi-Maharlooei, M., Zanetti, G., Mu, M., Fatima, H., … Izar, B. (2023). The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity. Cancer Cell, 41(7), 1207-1221.e12. https://doi.org/10.1016/j.ccell.2023.05.014
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Long, J., Soni, M., Muranski, P., Miller, M. J., Conry-Cantilena, C., & De Giorgi, V. (2023). Case Report: Kinetics and durability of humoral and cellular response of SARS-CoV-2 messenger RNA vaccine in a lung and kidney transplant recipient. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1207638
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See, S. B., Yang, X., Burger, C., Lamarthée, B., Snanoudj, R., Shihab, R., Tsapepas, D. S., Roy, P., Larivière-Beaudoin, S., Hamelin, K., Mendoza Rojas, A., van Besouw, N. M., Bartosic, A., Daniel, N., Rodica, V. E., Mohan, S., Cohen, D., Ratner, L., Baan, C. C., … Zorn, E. (2023). Natural Antibodies Are Associated With Rejection and Long-term Renal Allograft Loss in a Multicenter International Cohort. Transplantation, 107(7), 1580–1592. https://doi.org/10.1097/tp.0000000000004472
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Talaie, T., Wang, H., Kuo, W.-I., Danzl, N., Gulsen, M. R., Wolabaugh, A. N., Ding, X., Sykes, M., & Li, H. W. (2023). Origin, phenotype and autoimmune potential of T cells in human immune system mice receiving neonatal human thymus tissue. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1159341
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Long, K. D., & Fu, J. (2023). Chimerism and phenotypic analysis of intraepithelial and lamina propria T cells isolated from human ileal biopsies after intestinal transplantation. STAR Protocols, 4(2), 102192. https://doi.org/10.1016/j.xpro.2023.102192
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Mancuso, G., Bechi Genzano, C., Fierabracci, A., & Fousteri, G. (2023). Type 1 diabetes and inborn errors of immunity: Complete strangers or 2 sides of the same coin? Journal of Allergy and Clinical Immunology, 151(6), 1429–1447. https://doi.org/10.1016/j.jaci.2023.03.026
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Mashiko, S., Shihab, R. R., See, S. B., Schahadat, L. G. Z., Aguiar, T. F. M., Roy, P., Porcheray, F., & Zorn, E. (2023). Broad responses to chemical adducts shape the natural antibody repertoire in early infancy. Science Advances, 9(19). https://doi.org/10.1126/sciadv.ade8872
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Choe, J. H., Kawase, T., Xu, A., Guzman, A., Obradovic, A. Z., Low-Calle, A. M., Alaghebandan, B., Raghavan, A., Long, K., Hwang, P. M., Schiffman, J. D., Zhu, Y., Zhao, R., Lee, D.-F., Katz, C., & Prives, C. (2023). Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death. Cancer Discovery, 13(5), 1250–1273. https://doi.org/10.1158/2159-8290.cd-22-0882
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Sykes, M., Chandran, S., Kawai, T., Levitsky, J., Mapara, M., Mathew, J., Thomson, A., & Yamada, K. (2023). Meeting Report: The Fifth International Samuel Strober Workshop on Clinical Immune Tolerance. Transplantation, 107(3), 564–569. https://doi.org/10.1097/tp.0000000000004473
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Kang, J., Postigo-Fernandez, J., Kim, K., Zhu, C., Yu, J., Meroni, M., Mayfield, B., Bartolomé, A., Dapito, D. H., Ferrante, A. W., Dongiovanni, P., Valenti, L., Creusot, R. J., & Pajvani, U. B. (2023). Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis. JCI Insight, 8(3). https://doi.org/10.1172/jci.insight.165369
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Gartshteyn, Y., Askanase, A. D., Song, R., Bukhari, S., Dragovich, M., Adam, K., & Mor, A. (2022). SLAMF6 compartmentalization enhances T cell functions. Life Science Alliance, 6(2), e202201533. https://doi.org/10.26508/lsa.202201533
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Liang, X., Jordache, P., Greem, W., & Haddadian, E. J. (2023). Kinetic modelling of ligand trapping inside acidic vesicles containing alpha-4 beta-2 nicotinic receptors as an explanation for long-term cessation effect of varenicline (Chantix). Biophysical Journal, 122(3), 271a. https://doi.org/10.1016/j.bpj.2022.11.1549
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Lu, C., Ma, H., Song, L., Wang, H., Wang, L., Li, S., Lagana, S. M., Sepulveda, A. R., Hoebe, K., Pan, S. S., Yang, Y.-G., Lentzsch, S., & Mapara, M. Y. (2023). IFN-γR/STAT1 signaling in recipient hematopoietic antigen-presenting cells suppresses graft-versus-host disease. Journal of Clinical Investigation, 133(3). https://doi.org/10.1172/jci125986
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Fu, J., Rust, D., Fang, Z., Jiao, W., Lagana, S., Batal, I., Chen, B., Merl, S., Jones, R., Sykes, M., & Weiner, J. (2022). T cell repertoire profiling in allografts and native tissues in recipients with COVID–19 after solid organ transplantation: Insight into T cell–mediated allograft protection from viral infection. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.1056703
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Wang, Y., Fan, J. L., Melms, J. C., Amin, A. D., Georgis, Y., Barrera, I., Ho, P., Tagore, S., Abril-Rodríguez, G., He, S., Jin, Y., Biermann, J., Hofree, M., Caprio, L., Berhe, S., Khan, S. A., Henick, B. S., Ribas, A., Macosko, E. Z., … Izar, B. (2023). Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens. Nature Genetics, 55(1), 19–25. https://doi.org/10.1038/s41588-022-01268-9
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Bukhari, S., Henick, B. S., Winchester, R. J., Lerrer, S., Adam, K., Gartshteyn, Y., Maniar, R., Lin, Z., Khodadadi-Jamayran, A., Tsirigos, A., Salvatore, M. M., Lagos, G. G., Reiner, S. L., Dallos, M. C., Mathew, M., Rizvi, N. A., & Mor, A. (2023). Single-cell RNA sequencing reveals distinct T cell populations in immune-related adverse events of checkpoint inhibitors. Cell Reports Medicine, 4(1), 100868. https://doi.org/10.1016/j.xcrm.2022.100868
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Garry, D. J., Weiner, J. I., Greising, S. M., Sachs, D. H., & Garry, M. G. (2022). Xenotransplantation and exotransplantation: Strategies to expand the number of donor organs. Xenotransplantation, 30(1). Portico. https://doi.org/10.1111/xen.12786
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Du, W., Wang, J., Kuo, T., Wang, L., McKimpson, W. M., Son, J., Watanabe, H., Kitamoto, T., Lee, Y., Creusot, R. J., Ratner, L. E., McCune, K., Chen, Y.-W., Grubbs, B. H., Thornton, M. E., Fan, J., Sultana, N., Diaz, B. S., Balasubramanian, I., … Accili, D. (2022). Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals. Journal of Clinical Investigation, 132(24). https://doi.org/10.1172/jci162720
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Robertson, N., Wang, P., Talebloo, N., Yamada, K., & Moore, A. (2022). Synthesis of siRNA-Conjugated Dextran-Coated Iron Oxide Nanoparticles for Islet Protection During Transplantation and Noninvasive Imaging. Type-1 Diabetes, 163–174. https://doi.org/10.1007/978-1-0716-2807-2_11
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González, B. J., Zhao, H., Niu, J., Williams, D. J., Lee, J., Goulbourne, C. N., Xing, Y., Wang, Y., Oberholzer, J., Blumenkrantz, M. H., Chen, X., LeDuc, C. A., Chung, W. K., Colecraft, H. M., Gromada, J., Shen, Y., Goland, R. S., Leibel, R. L., & Egli, D. (2022). Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency. Communications Biology, 5(1). https://doi.org/10.1038/s42003-022-03696-z
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