Center for Translational Immunology

Displaying 101 - 150 of 196CSV
Sykes, M., Chandran, S., Kawai, T., Levitsky, J., Mapara, M., Mathew, J., Thomson, A., & Yamada, K. (2023). Meeting Report: The Fifth International Samuel Strober Workshop on Clinical Immune Tolerance. Transplantation, 107(3), 564–569. https://doi.org/10.1097/tp.0000000000004473
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Kang, J., Postigo-Fernandez, J., Kim, K., Zhu, C., Yu, J., Meroni, M., Mayfield, B., Bartolomé, A., Dapito, D. H., Ferrante, A. W., Dongiovanni, P., Valenti, L., Creusot, R. J., & Pajvani, U. B. (2023). Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis. JCI Insight, 8(3). https://doi.org/10.1172/jci.insight.165369
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Liang, X., Jordache, P., Greem, W., & Haddadian, E. J. (2023). Kinetic modelling of ligand trapping inside acidic vesicles containing alpha-4 beta-2 nicotinic receptors as an explanation for long-term cessation effect of varenicline (Chantix). Biophysical Journal, 122(3), 271a. https://doi.org/10.1016/j.bpj.2022.11.1549
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Lu, C., Ma, H., Song, L., Wang, H., Wang, L., Li, S., Lagana, S. M., Sepulveda, A. R., Hoebe, K., Pan, S. S., Yang, Y.-G., Lentzsch, S., & Mapara, M. Y. (2023). IFN-γR/STAT1 signaling in recipient hematopoietic antigen-presenting cells suppresses graft-versus-host disease. Journal of Clinical Investigation, 133(3). https://doi.org/10.1172/jci125986
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Gartshteyn, Y., Askanase, A. D., Song, R., Bukhari, S., Dragovich, M., Adam, K., & Mor, A. (2022). SLAMF6 compartmentalization enhances T cell functions. Life Science Alliance, 6(2), e202201533. https://doi.org/10.26508/lsa.202201533
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Fu, J., Rust, D., Fang, Z., Jiao, W., Lagana, S., Batal, I., Chen, B., Merl, S., Jones, R., Sykes, M., & Weiner, J. (2022). T cell repertoire profiling in allografts and native tissues in recipients with COVID–19 after solid organ transplantation: Insight into T cell–mediated allograft protection from viral infection. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.1056703
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Garry, D. J., Weiner, J. I., Greising, S. M., Sachs, D. H., & Garry, M. G. (2022). Xenotransplantation and exotransplantation: Strategies to expand the number of donor organs. Xenotransplantation, 30(1). Portico. https://doi.org/10.1111/xen.12786
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Wang, Y., Fan, J. L., Melms, J. C., Amin, A. D., Georgis, Y., Barrera, I., Ho, P., Tagore, S., Abril-Rodríguez, G., He, S., Jin, Y., Biermann, J., Hofree, M., Caprio, L., Berhe, S., Khan, S. A., Henick, B. S., Ribas, A., Macosko, E. Z., … Izar, B. (2023). Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens. Nature Genetics, 55(1), 19–25. https://doi.org/10.1038/s41588-022-01268-9
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Bukhari, S., Henick, B. S., Winchester, R. J., Lerrer, S., Adam, K., Gartshteyn, Y., Maniar, R., Lin, Z., Khodadadi-Jamayran, A., Tsirigos, A., Salvatore, M. M., Lagos, G. G., Reiner, S. L., Dallos, M. C., Mathew, M., Rizvi, N. A., & Mor, A. (2023). Single-cell RNA sequencing reveals distinct T cell populations in immune-related adverse events of checkpoint inhibitors. Cell Reports Medicine, 4(1), 100868. https://doi.org/10.1016/j.xcrm.2022.100868
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Du, W., Wang, J., Kuo, T., Wang, L., McKimpson, W. M., Son, J., Watanabe, H., Kitamoto, T., Lee, Y., Creusot, R. J., Ratner, L. E., McCune, K., Chen, Y.-W., Grubbs, B. H., Thornton, M. E., Fan, J., Sultana, N., Diaz, B. S., Balasubramanian, I., … Accili, D. (2022). Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals. Journal of Clinical Investigation, 132(24). https://doi.org/10.1172/jci162720
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Robertson, N., Wang, P., Talebloo, N., Yamada, K., & Moore, A. (2022). Synthesis of siRNA-Conjugated Dextran-Coated Iron Oxide Nanoparticles for Islet Protection During Transplantation and Noninvasive Imaging. Type-1 Diabetes, 163–174. https://doi.org/10.1007/978-1-0716-2807-2_11
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Li, Y., Wu, Y., Federzoni, E. A., Wang, X., Dharmawan, A., Hu, X., Wang, H., Hawley, R. J., Stevens, S., Sykes, M., & Yang, Y.-G. (2022). CD47 cross-dressing by extracellular vesicles expressing CD47 inhibits phagocytosis without transmitting cell death signals. ELife, 11. CLOCKSS. https://doi.org/10.7554/elife.73677
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Anandakumaran, P. N., Ayers, A. G., Muranski, P., Creusot, R. J., & Sia, S. K. (2022). Rapid video-based deep learning of cognate versus non-cognate T cell-dendritic cell interactions. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-021-04286-5
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González, B. J., Zhao, H., Niu, J., Williams, D. J., Lee, J., Goulbourne, C. N., Xing, Y., Wang, Y., Oberholzer, J., Blumenkrantz, M. H., Chen, X., LeDuc, C. A., Chung, W. K., Colecraft, H. M., Gromada, J., Shen, Y., Goland, R. S., Leibel, R. L., & Egli, D. (2022). Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency. Communications Biology, 5(1). https://doi.org/10.1038/s42003-022-03696-z
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Strazza, M., Moore, E. K., Adam, K., Azoulay-Alfaguter, I., & Mor, A. (2022). Neutralization of the adaptor protein PAG by monoclonal antibody limits murine tumor growth. Molecular Therapy - Methods & Clinical Development, 27, 380–390. https://doi.org/10.1016/j.omtm.2022.10.012
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Ural, B. B., Caron, D. P., Dogra, P., Wells, S. B., Szabo, P. A., Granot, T., Senda, T., Poon, M. M. L., Lam, N., Thapa, P., Lee, Y. S., Kubota, M., Matsumoto, R., & Farber, D. L. (2022). Inhaled particulate accumulation with age impairs immune function and architecture in human lung lymph nodes. Nature Medicine, 28(12), 2622–2632. https://doi.org/10.1038/s41591-022-02073-x
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Giangreco, N. P., Lebreton, G., Restaino, S., Farr, M., Zorn, E., Colombo, P. C., Patel, J., Soni, R. K., Leprince, P., Kobashigawa, J., Tatonetti, N. P., & Fine, B. M. (2022). Alterations in the kallikrein-kinin system predict death after heart transplant. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-18573-2
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Breyer, L. M., Wang, H., Gu, D., Johnstone, B. H., Ma, H., Woods, E. J., & Mapara, M. Y. (2022). Transplantation of Hematopoietic Stem and Progenitor Cells from Cadaveric Organ Donors Leads to Long-Term Multilineage Engraftment in NSG Mice. Blood, 140(Supplement 1), 7347–7348. https://doi.org/10.1182/blood-2022-169787
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Walters, M. C., Thompson, A. A., Kwiatkowski, J. L., Parikh, S., Mapara, M. Y., Rifkin-Zenenberg, S., Aygun, B., Kasow, K. A., Miller, A., Zhang, L., Chawla, A., Macari, E. R., Pierciey, F. J., Tisdale, J. F., & Kanter, J. (2022). Lovo-cel (bb1111) Gene Therapy for Sickle Cell Disease: Updated Clinical Results and Investigations into Two Cases of Anemia from Group C of the Phase 1/2 HGB-206 Study. Blood, 140(Supplement 1), 26–28. https://doi.org/10.1182/blood-2022-162288
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Fu, J., Li, S., Ma, H., Yang, J., Brown, L. M., Pagnotti, G. M., Weiss, S. J., Mapara, M. Y., & Lentzsch, S. (2022). The Novel Role of Checkpoint Inhibitor PD-1H/VISTA in Osteoclast Cytoskeleton Regulation and Multiple Myeloma Bone Disease. Blood, 140(Supplement 1), 9930–9932. https://doi.org/10.1182/blood-2022-169921
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Garry, D. J., Weiner, J. I., Greising, S. M., Garry, M. G., & Sachs, D. H. (2022). Mechanisms and strategies to promote cardiac xenotransplantation. Journal of Molecular and Cellular Cardiology, 172, 109–119. https://doi.org/10.1016/j.yjmcc.2022.07.013
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Park, K. W., Yang, H., Lee, M. G., Ock, S. A., Wi, H., Lee, P., Hwang, I.-S., Yoo, J. G., Park, C.-K., & Lee, B. R. (2022). Establishment of intestinal organoids from small intestine of growing cattle (12 months old). Journal of Animal Science and Technology, 64(6), 1105–1116. https://doi.org/10.5187/jast.2022.e70
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Tavaré, R., Danton, M., Giurleo, J. T., Makonnen, S., Hickey, C., Arnold, T. C., Kelly, M. P., Fredriksson, F., Bruestle, K., Hermann, A., Ullman, E., Edelmann, K. H., Potocky, T., Dudgeon, D., Bhatt, N. B., Doubrovin, M., Barry, T., Kyratsous, C. A., Gurer, C., … Kirshner, J. R. (2022). Immuno-PET Monitoring of Lymphocytes Using the CD8-Specific Antibody REGN5054. Cancer Immunology Research, 10(10), 1190–1209. https://doi.org/10.1158/2326-6066.cir-21-0405
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Garry, D. J., Weiner, J. I., Greising, S. M., Garry, M. G., & Sachs, D. H. (2022). Cardiac Xenotransplantation: Clinical Impact of Science and Discovery. Circulation, 146(13), 961–963. https://doi.org/10.1161/circulationaha.122.059191
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Huang, H., Fang, Y., Jiang, M., Zhang, Y., Biermann, J., Melms, J. C., Danielsson, J. A., Yang, Y., Qiang, L., Liu, J., Zhou, Y., Wang, M., Hu, Z., Wang, T. C., Saqi, A., Sun, J., Matsumoto, I., Cardoso, W. V., Emala, C. W., … Que, J. (2022). Contribution of Trp63CreERT2-labeled cells to alveolar regeneration is independent of tuft cells. ELife, 11. CLOCKSS. https://doi.org/10.7554/elife.78217
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Langouo Fontsa, M., Aiello, M. M., Migliori, E., Scartozzi, M., Lambertini, M., Willard-Gallo, K., & Solinas, C. (2022). Thromboembolism and Immune Checkpoint Blockade in Cancer Patients: An Old Foe for New Research. Targeted Oncology, 17(5), 497–505. https://doi.org/10.1007/s11523-022-00908-8
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Fu, J., Wang, Z., Martinez, M., Jiao, W., Frangaj, K., Jones, R., Guo, X. V., Zhang, Y., Kuo, W.-I., Obradovic, A., Ma, W., Rogers, K., Kato, T., Shen, Y., & Sykes, M. (2022). 425.3: Single-Cell Immune Profiling of Human Intestinal Allografts Reveals Differential Phenotypes of Alloreactive T-Cell Clones in Quiescent vs Chronically Rejecting Allografts. Transplantation, 106(9S), S485–S485. https://doi.org/10.1097/01.tp.0000888048.23424.42
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Adam, K., & Mor, A. (2022). Immunohistochemistry of Immune Cells and Cells Bound to in vivo Administered Antibodies in Liver, Lung, Pancreas, and Colon of B6/lpr Mice. BIO-PROTOCOL, 12(14). https://doi.org/10.21769/bioprotoc.4468
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Greising, S. M., Weiner, J. I., Garry, D. J., Sachs, D. H., & Garry, M. G. (2022). Human muscle in gene edited pigs for treatment of volumetric muscle loss. Frontiers in Genetics, 13. https://doi.org/10.3389/fgene.2022.948496
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Ahn, J., Lee, J., Kim, D.-H., Hwang, I.-S., Park, M.-R., Cho, I.-C., Hwang, S., & Lee, K. (2022). Loss of Monoallelic Expression of IGF2 in the Adult Liver Via Alternative Promoter Usage and Chromatin Reorganization. Frontiers in Genetics, 13. https://doi.org/10.3389/fgene.2022.920641
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Alvarez-Breckenridge, C., Markson, S. C., Stocking, J. H., Nayyar, N., Lastrapes, M., Strickland, M. R., Kim, A. E., de Sauvage, M., Dahal, A., Larson, J. M., Mora, J. L., Navia, A. W., Klein, R. H., Kuter, B. M., Gill, C. M., Bertalan, M., Shaw, B., Kaplan, A., Subramanian, M., … Carter, S. L. (2022). Microenvironmental Landscape of Human Melanoma Brain Metastases in Response to Immune Checkpoint Inhibition. Cancer Immunology Research, 10(8), 996–1012. https://doi.org/10.1158/2326-6066.cir-21-0870
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Hwang, I.-S., Shim, J., Oh, K. B., Lee, H., & Park, M.-R. (2022). cd26 Knockdown Negatively Affects Porcine Parthenogenetic Preimplantation Embryo Development. Animals, 12(13), 1662. https://doi.org/10.3390/ani12131662
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Biermann, J., Melms, J. C., Amin, A. D., Wang, Y., Caprio, L. A., Karz, A., Tagore, S., Barrera, I., Ibarra-Arellano, M. A., Andreatta, M., Fullerton, B. T., Gretarsson, K. H., Sahu, V., Mangipudy, V. S., Nguyen, T. T. T., Nair, A., Rogava, M., Ho, P., Koch, P. D., … Izar, B. (2022). Dissecting the treatment-naive ecosystem of human melanoma brain metastasis. Cell, 185(14), 2591-2608.e30. https://doi.org/10.1016/j.cell.2022.06.007
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Vecchione, A., Madley, R., Danzl, N., Borsotti, C., Marharlooei, M. K., Li, H.-W., Nauman, G., Ding, X., Ho, S.-H., Fousteri, G., & Sykes, M. (2022). T1D patient-derived hematopoietic stem cells are programmed to generate Tph, Tfh, and autoimmunity-associated B cell subsets in human immune system mice. Clinical Immunology, 240, 109048. https://doi.org/10.1016/j.clim.2022.109048
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Liu, C., Lin, B., Wu, M., Song, Y., Ke, T., Chou, Y., Liu, C., Lin, C., Radojcic, V., Drake, C., & Yen, H. (2022). Adoptive transfer of IL‐4 reprogrammed Tc17 cells elicits anti‐tumour immunity through functional plasticity. Immunology, 166(3), 310–326. Portico. https://doi.org/10.1111/imm.13473
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Park, K. W., Yang, H., Wi, H., Ock, S. A., Lee, P., Hwang, I.-S., & Lee, B. R. (2022). Effect of Wnt signaling pathway activation on the efficient generation of bovine intestinal organoids. Journal of Animal Reproduction and Biotechnology, 37(2), 136–143. https://doi.org/10.12750/jarb.37.2.136
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Eisenson, D. L., Hisadome, Y., & Yamada, K. (2022). Progress in Xenotransplantation: Immunologic Barriers, Advances in Gene Editing, and Successful Tolerance Induction Strategies in Pig-To-Primate Transplantation. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.899657
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Montgomery, R. A., Stern, J. M., Lonze, B. E., Tatapudi, V. S., Mangiola, M., Wu, M., Weldon, E., Lawson, N., Deterville, C., Dieter, R. A., Sullivan, B., Boulton, G., Parent, B., Piper, G., Sommer, P., Cawthon, S., Duggan, E., Ayares, D., Dandro, A., … Stewart, Z. A. (2022). Results of Two Cases of Pig-to-Human Kidney Xenotransplantation. New England Journal of Medicine, 386(20), 1889–1898. https://doi.org/10.1056/nejmoa2120238
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Obradovic, A., Graves, D., Korrer, M., Wang, Y., Roy, S., Naveed, A., Xu, Y., Luginbuhl, A., Curry, J., Gibson, M., Idrees, K., Hurley, P., Jiang, P., Liu, X. S., Uppaluri, R., Drake, C. G., Califano, A., & Kim, Y. J. (2022). Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck Cancer. Clinical Cancer Research, 28(10), 2094–2109. https://doi.org/10.1158/1078-0432.ccr-21-3570
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Jaiswal, A., Verma, A., Dannenfelser, R., Melssen, M., Tirosh, I., Izar, B., Kim, T.-G., Nirschl, C. J., Devi, K. S. P., Olson, W. C., Slingluff, C. L., Engelhard, V. H., Garraway, L., Regev, A., Minkis, K., Yoon, C. H., Troyanskaya, O., Elemento, O., Suárez-Fariñas, M., & Anandasabapathy, N. (2022). An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes. Cancer Cell, 40(5), 524-544.e5. https://doi.org/10.1016/j.ccell.2022.04.005
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Gras-Peña, R., Danzl, N. M., Khosravi-Maharlooei, M., Campbell, S. R., Ruiz, A. E., Parks, C. A., Suen Savage, W. M., Holzl, M. A., Chatterjee, D., & Sykes, M. (2022). Human stem cell-derived thymic epithelial cells enhance human T-cell development in a xenogeneic thymus. Journal of Allergy and Clinical Immunology, 149(5), 1755–1771. https://doi.org/10.1016/j.jaci.2021.09.038
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Reed, E. F., Chong, A. S., Levings, M. K., Mutrie, C., Laufer, T. M., Roncarolo, M. G., & Sykes, M. (2022). The Women of FOCIS: Promoting Equality and Inclusiveness in a Professional Federation of Clinical Immunology Societies. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.816535
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