da Costa, B. L., Caruso, S. M., Tsai, Y.-T., Castillejos, D. S., Sylla, M., Tsang, S. H., & Quinn, P. M. J. (2025). Prime Editing Strategy to Install the RPE65 c.1430A>G Dominant Mutation. Retinal Degenerative Diseases XX, 101–106. https://doi.org/10.1007/978-3-031-76550-6_17

da Costa, B. L., Knudsen, A. S., Alves, C. H., Tsang, S. H., & Quinn, P. M. J. (2025). Megabase Deletion of the Human EYS Locus Using CRISPR/Cas9. Retinal Degenerative Diseases XX, 107–111. https://doi.org/10.1007/978-3-031-76550-6_18

Xu, C., He, S., Zhu, Y., Crasto, G., Chen, C., Clay, M. L., Lao, Y.-H., & Leong, K. W. (2024). Vascular Organoid Generation from Human-Induced Pluripotent Stem Cells. Journal of Visualized Experiments, 214. https://doi.org/10.3791/67125

Bosco, P., Akcan, U., Williams, D., Buchanan, H. M., Agalliu, D., & Sproul, A. A. (2024). Generating iAstrocytes From Human Induced Pluripotent Stem Cells by Combining Low‐Density Passaging of Neural Progenitor Cells and Transcription Factor NFIA Transdifferentiation. Current Protocols, 4(11). Portico. https://doi.org/10.1002/cpz1.70049

Marshall, E. M., Bauer, L., Nelemans, T., Sooksawasdi Na Ayudhya, S., Benavides, F., Lanko, K., de Vrij, F. M. S., Kushner, S. A., Koopmans, M., van Riel, D., & Rockx, B. (2024). Differential susceptibility of human motor neurons to infection with Usutu and West Nile virus. Journal of Neuroinflammation, 21(1). https://doi.org/10.1186/s12974-024-03228-y

Chen, Y., Chauhan, S., Gong, C., Dayton, H., Xu, C., De La Cruz, E. D., Tsai, Y.-Y. W., Datta, M. S., Rosoklija, G. B., Dwork, A. J., Mann, J. J., Boldrini, M., Leong, K. W., Dietrich, L. E. P., & Tomer, R. (2024). Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples. Nature Biomedical Engineering, 8(9), 1109–1123. https://doi.org/10.1038/s41551-024-01249-9

Wu, Q., Rafatian, N., Wagner, K. T., Blamer, J., Smith, J., Okhovatian, S., Aggarwal, P., Wang, E. Y., Banerjee, A., Zhao, Y., Nash, T. R., Lu, R. X. Z., Portillo-Esquivel, L. E., Li, C. Y., Kuzmanov, U., Mandla, S., Virlee, E., Landau, S., Lai, B. F., … Radisic, M. (2024). SARS-CoV-2 pathogenesis in an angiotensin II–induced heart-on-a-chip disease model and extracellular vesicle screening. Proceedings of the National Academy of Sciences, 121(28). https://doi.org/10.1073/pnas.2403581121

Lock, R. I., Graney, P. L., Tavakol, D. N., Nash, T. R., Kim, Y., Sanchez, E., Morsink, M., Ning, D., Chen, C., Fleischer, S., Baldassarri, I., & Vunjak-Novakovic, G. (2024). Macrophages enhance contractile force in iPSC-derived human engineered cardiac tissue. Cell Reports, 43(6), 114302. https://doi.org/10.1016/j.celrep.2024.114302

Qu, W., Lam, M., McInvale, J. J., Mares, J. A., Kwon, S., Humala, N., Mahajan, A., Nguyen, T., Jakubiak, K. A., Mun, J.-Y., Tedesco, T. G., Al-Dalahmah, O., Hussaini, S. A., Sproul, A. A., Siegelin, M. D., De Jager, P. L., Canoll, P., Menon, V., & Hargus, G. (2024). Xenografted human iPSC-derived neurons with the familial Alzheimer’s disease APPV717I mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator. Acta Neuropathologica, 147(1). https://doi.org/10.1007/s00401-024-02755-5

Teles, D., & Fine, B. M. (2024). Using induced pluripotent stem cells for drug discovery in arrhythmias. Expert Opinion on Drug Discovery, 19(7), 827–840. https://doi.org/10.1080/17460441.2024.2360420

Gordillo-Sampedro, S., Antounians, L., Wei, W., Mufteev, M., Lendemeijer, B., Kushner, S. A., de Vrij, F. M. S., Zani, A., & Ellis, J. (2024). iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles. Molecular and Cellular Neuroscience, 129, 103933. https://doi.org/10.1016/j.mcn.2024.103933

Zhao, Y., Chukanova, M., Kentistou, K. A., Fairhurst-Hunter, Z., Siegert, A. M., Jia, R. Y., Dowsett, G. K. C., Gardner, E. J., Lawler, K., Day, F. R., Kaisinger, L. R., Tung, Y.-C. L., Lam, B. Y. H., Chen, H.-J. C., Wang, Q., Berumen-Campos, J., Kuri-Morales, P., Tapia-Conyer, R., Alegre-Diaz, J., … Perry, J. R. B. (2024). Protein-truncating variants in BSN are associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease. Nature Genetics, 56(4), 579–584. https://doi.org/10.1038/s41588-024-01694-x

Xiao, F., Zhang, X., Morton, S. U., Kim, S. W., Fan, Y., Gorham, J. M., Zhang, H., Berkson, P. J., Mazumdar, N., Cao, Y., Chen, J., Hagen, J., Liu, X., Zhou, P., Richter, F., Shen, Y., Ward, T., Gelb, B. D., Seidman, J. G., … Pu, W. T. (2024). Functional dissection of human cardiac enhancers and noncoding de novo variants in congenital heart disease. Nature Genetics, 56(3), 420–430. https://doi.org/10.1038/s41588-024-01669-y

Cherkaoui, I., Du, Q., Egli, D., Misra, S., & Rutter, G. A. (2024). Optimized Protocol for Generating Functional Pancreatic Insulin-secreting Cells from Human Pluripotent Stem Cells. Journal of Visualized Experiments, 204. https://doi.org/10.3791/65530

McInvale, J. J., Canoll, P., & Hargus, G. (2024). Induced pluripotent stem cell models as a tool to investigate and test fluid biomarkers in Alzheimer’s disease and frontotemporal dementia. Brain Pathology, 34(4). Portico. https://doi.org/10.1111/bpa.13231

Abela, L., Gianfrancesco, L., Tagliatti, E., Rossignoli, G., Barwick, K., Zourray, C., Reid, K. M., Budinger, D., Ng, J., Counsell, J., Simpson, A., Pearson, T. S., Edvardson, S., Elpeleg, O., Brodsky, F. M., Lignani, G., Barral, S., & Kurian, M. A. (2024). Neurodevelopmental and synaptic defects in DNAJC6 parkinsonism, amenable to gene therapy. Brain, 147(6), 2023–2037. https://doi.org/10.1093/brain/awae020

Heins-Marroquin, U., Singh, R. R., Perathoner, S., Gavotto, F., Merino Ruiz, C., Patraskaki, M., Gomez-Giro, G., Kleine Borgmann, F., Meyer, M., Carpentier, A., Warmoes, M. O., Jäger, C., Mittelbronn, M., Schwamborn, J. C., Cordero-Maldonado, M. L., Crawford, A. D., Schymanski, E. L., & Linster, C. L. (2024). CLN3 deficiency leads to neurological and metabolic perturbations during early development. Life Science Alliance, 7(3), e202302057. https://doi.org/10.26508/lsa.202302057

MacCarthy, C. M., Wu, G., Malik, V., Menuchin-Lasowski, Y., Velychko, T., Keshet, G., Fan, R., Bedzhov, I., Church, G. M., Jauch, R., Cojocaru, V., Schöler, H. R., & Velychko, S. (2024). Highly cooperative chimeric super-SOX induces naive pluripotency across species. Cell Stem Cell, 31(1), 127-147.e9. https://doi.org/10.1016/j.stem.2023.11.010

da Costa, B. L., Li, Y., Levi, S. R., Tsang, S. H., & Quinn, P. M. J. (2023). Generation of CRB1 RP Patient-Derived iPSCs and a CRISPR/Cas9-Mediated Homology-Directed Repair Strategy for the CRB1 c.2480G>T Mutation. Retinal Degenerative Diseases XIX, 571–576. https://doi.org/10.1007/978-3-031-27681-1_83

Wu, J. Y., Yeager, K., Tavakol, D. N., Morsink, M., Wang, B., Soni, R. K., Hung, C. T., & Vunjak-Novakovic, G. (2023). Directed differentiation of human iPSCs into mesenchymal lineages by optogenetic control of TGF-β signaling. Cell Reports, 42(5), 112509. https://doi.org/10.1016/j.celrep.2023.112509

Garcia-Epelboim, A., & Christian, K. M. (2023). Modeling neuro-immune interactions using human pluripotent stem cells. Current Opinion in Neurobiology, 79, 102672. https://doi.org/10.1016/j.conb.2022.102672

Liao, X., Kennel, P. J., Liu, B., Nash, T. R., Zhuang, R. Z., Godier-Furnemont, A. F., Xue, C., Lu, R., Colombo, P. C., Uriel, N., Reilly, M. P., Marx, S. O., Vunjak-Novakovic, G., & Topkara, V. K. (2023). Effect of mechanical unloading on genome-wide DNA methylation profile of the failing human heart. JCI Insight, 8(4). https://doi.org/10.1172/jci.insight.161788

Vaughan-Jackson, A., Stodolak, S., Ebrahimi, K. H., Johnson, E., Reardon, P. K., Dupont, M., Zhang, S., McCullagh, J. S. O., & James, W. S. (2022). Density dependent regulation of inflammatory responses in macrophages. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.895488

Limone, F., Guerra San Juan, I., Mitchell, J. M., Smith, J. L. M., Raghunathan, K., Meyer, D., Ghosh, S. D., Couto, A., Klim, J. R., Joseph, B. J., Gold, J., Mello, C. J., Nemesh, J., Smith, B. M., Verhage, M., McCarroll, S. A., Pietiläinen, O., Nehme, R., & Eggan, K. (2023). Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues. Cell Reports, 42(1), 111896. https://doi.org/10.1016/j.celrep.2022.111896

Kim, Y. A., Siddiqui, T., Blaze, J., Cosacak, M. I., Winters, T., Kumar, A., Tein, E., Sproul, A. A., Teich, A. F., Bartolini, F., Akbarian, S., Kizil, C., Hargus, G., & Santa-Maria, I. (2022). RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation. Acta Neuropathologica, 145(1), 29–48. https://doi.org/10.1007/s00401-022-02511-7

Chang, Y.-J., Cui, X., Levi, S. R., Jenny, L. A., & Tsang, S. H. (2022). CRISPR Manipulations in Stem Cell Lines. Retinitis Pigmentosa, 249–256. https://doi.org/10.1007/978-1-0716-2651-1_23

Tso, A., da Costa, B. L., Fehnel, A., Levi, S. R., Jenny, L. A., Ragi, S. D., Li, Y., & Quinn, P. M. J. (2022). Generation of Human iPSC-Derived Retinal Organoids for Assessment of AAV-Mediated Gene Delivery. Retinitis Pigmentosa, 287–302. https://doi.org/10.1007/978-1-0716-2651-1_27

Bernardin, A. A., Colombani, S., Rousselot, A., Andry, V., Goumon, Y., Delanoë-Ayari, H., Pasqualin, C., Brugg, B., Jacotot, E. D., Pasquié, J.-L., Lacampagne, A., & Meli, A. C. (2022). Impact of Neurons on Patient-Derived Cardiomyocytes Using Organ-On-A-Chip and iPSC Biotechnologies. Cells, 11(23), 3764. https://doi.org/10.3390/cells11233764

Su, P.-Y., Lee, W., Zernant, J., Tsang, S. H., Nagasaki, T., Corneo, B., & Allikmets, R. (2022). Establishment of the iPSC line CUIMCi005-A from a patient with Stargardt disease for retinal organoid culture. Stem Cell Research, 65, 102973. https://doi.org/10.1016/j.scr.2022.102973

Tanaka, J., Senpuku, H., Ogawa, M., Yasuhara, R., Ohnuma, S., Takamatsu, K., Watanabe, T., Mabuchi, Y., Nakamura, S., Ishida, S., Sadaoka, T., Takaki, T., Shirota, T., Shimane, T., Inoue, T., Sakai, T., Mori, M., Tsuji, T., Saito, I., & Mishima, K. (2022). Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication. Nature Cell Biology, 24(11), 1595–1605. https://doi.org/10.1038/s41556-022-01007-6

Stutzman, M. J., Kim, C. S. J., Tester, D. J., Hamrick, S. K., Dotzler, S. M., Giudicessi, J. R., Miotto, M. C., GC, J. B., Frank, J., Marks, A. R., & Ackerman, M. J. (2022). Characterization of N-terminal RYR2 variants outside CPVT1 hotspot regions using patient iPSCs reveal pathogenesis and therapeutic potential. Stem Cell Reports, 17(9), 2023–2036. https://doi.org/10.1016/j.stemcr.2022.07.002

Shen, S., Sewanan, L. R., Shao, S., Halder, S. S., Stankey, P., Li, X., & Campbell, S. G. (2022). Physiological calcium combined with electrical pacing accelerates maturation of human engineered heart tissue. Stem Cell Reports, 17(9), 2037–2049. https://doi.org/10.1016/j.stemcr.2022.07.006

Cho, S., Discher, D. E., Leong, K. W., Vunjak-Novakovic, G., & Wu, J. C. (2022). Challenges and opportunities for the next generation of cardiovascular tissue engineering. Nature Methods, 19(9), 1064–1071. https://doi.org/10.1038/s41592-022-01591-3

Patel, A., Iannello, G., Diaz, A. G., Sirabella, D., Thaker, V., & Corneo, B. (2022). Efficient Cas9‐based Genome Editing Using CRISPR Analysis Webtools in Severe Early‐onset‐obesity Patient‐derived iPSCs. Current Protocols, 2(8). Portico. https://doi.org/10.1002/cpz1.519

Zhang, X., Wang, B. Z., Kim, M., Nash, T. R., Liu, B., Rao, J., Lock, R., Tamargo, M., Soni, R. K., Belov, J., Li, E., Vunjak-Novakovic, G., & Fine, B. (2022). STK25 inhibits PKA signaling by phosphorylating PRKAR1A. Cell Reports, 40(7), 111203. https://doi.org/10.1016/j.celrep.2022.111203

Wu, J. Y., & Vunjak-Novakovic, G. (2022). Bioengineering Human Cartilage–Bone Tissues for Modeling of Osteoarthritis. Stem Cells and Development, 31(15–16), 399–405. https://doi.org/10.1089/scd.2021.0317

Torriano, S., Baulier, E., Garcia Diaz, A., Corneo, B., & Farber, D. B. (2022). CRISPR-AsCas12a Efficiently Corrects a GPR143 Intronic Mutation in Induced Pluripotent Stem Cells from an Ocular Albinism Patient. The CRISPR Journal, 5(3), 457–471. https://doi.org/10.1089/crispr.2021.0110

Raad, S., David, A., Chung, W., & Faure, C. (2022). Generation of three induced pluripotent stem cells lines from patients with esophageal atresia/tracheoesophageal fistula type C. Stem Cell Research, 60, 102711. https://doi.org/10.1016/j.scr.2022.102711