iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles

Gordillo-Sampedro, S., Antounians, L., Wei, W., Mufteev, M., Lendemeijer, B., Kushner, S. A., de Vrij, F. M. S., Zani, A., & Ellis, J. (2024). iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles. Molecular and Cellular Neuroscience, 129, 103933. https://doi.org/10.1016/j.mcn.2024.103933
Authors:
Sara Gordillo-Sampedro
Lina Antounians
Wei Wei
Marat Mufteev
Bas Lendemeijer
Steven A Kushner
Femke M S de Vrij
Augusto Zani
James Ellis
Affiliated Authors:
Bas Lendemeijer
Steven A Kushner
Columbia Affiliation:
Subjects:
Exosome Biology and Function in Intercellular Communication (OpenAlex Topic)
MicroRNA Regulation in Cancer and Development (OpenAlex Topic)
Mechanisms and Applications of RNA Interference (OpenAlex Topic)
Extracellular Vesicles (MeSH)
Induced Pluripotent Stem Cells (MeSH)
MicroRNAs (MeSH)
Astrocytes (MeSH)
Neurons (MeSH)
Author Keywords:
astrocytes
blood biomarker
extracellular vesicles
induced pluripotent stem cells
microrna
mir-483-5p
rett syndrome
rna binding proteins
elink
Publication Type:
Article
Unique ID:
10.1016/j.mcn.2024.103933
PMID:
38663691
DOI:
10.1016/j.mcn.2024.103933
Journal:
Molecular and Cellular Neurosciences
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created: