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Lin, C.-C., Fang, K.-C., Balbo, I., Liang, T.-Y., Liu, C.-W., Liu, W.-C., Wang, Y.-M., Hung, Y.-L., Yang, K.-C., Geng, S. K., Ni, C.-L., Driscoll, C. P., Ruff, D. S., Kumar, A., Amokrane, N., Desai, N., Faust, P. L., Louis, E. D., Kuo, S.-H., & Pan, M.-K. (2025). Reduced cerebellar rhythm by climbing fiber denervation is linked to motor rhythm deficits in mice and ataxia severity in patients. Science Translational Medicine, 17(787). https://doi.org/10.1126/scitranslmed.adk3922

Tonsho, M., O, J. M., Ahrens, K., Robinson, K., Sommer, W., Boskovic, S., Patel, P. M., Becerra, D. C., Huh, K. H., Miller, C. L., Dehnadi, A., Hanekamp, I., Rosales, I. A., Colvin, R. B., Sachs, D. H., Alessandrini, A., Cosimi, A., Fairchild, R. L., Cravedi, P., … Madsen, J. C. (2025). Cardiac allograft tolerance can be achieved in nonhuman primates by donor bone marrow and kidney cotransplantation. Science Translational Medicine, 17(782). https://doi.org/10.1126/scitranslmed.ads0255

Bisikirska, B., Labella, R., Cuesta-Dominguez, A., Luo, N., De Angelis, J., Mosialou, I., Lin, C.-S., Beck, D., Lata, S., Shyu, P. T., McMahon, D. J., Guo, E., Hagen, J., Chung, W. K., Shane, E., Cohen, A., & Kousteni, S. (2024). Melatonin receptor 1A variants as genetic cause of idiopathic osteoporosis. Science Translational Medicine, 16(769). https://doi.org/10.1126/scitranslmed.adj0085

Lagier, D., Zeng, C., Kaczka, D. W., Zhu, M., Grogg, K., Gerard, S. E., Reinhardt, J. M., Ribeiro, G. C. M., Rashid, A., Winkler, T., & Vidal Melo, M. F. (2024). Mechanical ventilation guided by driving pressure optimizes local pulmonary biomechanics in an ovine model. Science Translational Medicine, 16(760). https://doi.org/10.1126/scitranslmed.ado1097

Wang, Y.-M., Liu, C.-W., Chen, S.-Y., Lu, L.-Y., Liu, W.-C., Wang, J.-H., Ni, C.-L., Wong, S.-B., Kumar, A., Lee, J.-C., Kuo, S.-H., Wu, S.-C., & Pan, M.-K. (2024). Neuronal population activity in the olivocerebellum encodes the frequency of essential tremor in mice and patients. Science Translational Medicine, 16(747). https://doi.org/10.1126/scitranslmed.adl1408

Neo, S. Y., Tong, L., Chong, J., Liu, Y., Jing, X., Oliveira, M. M. S., Chen, Y., Chen, Z., Lee, K., Burduli, N., Chen, X., Gao, J., Ma, R., Lim, J. P., Huo, J., Xu, S., Alici, E., Wickström, S. L., Haglund, F., … Lundqvist, A. (2024). Tumor-associated NK cells drive MDSC-mediated tumor immune tolerance through the IL-6/STAT3 axis. Science Translational Medicine, 16(747). https://doi.org/10.1126/scitranslmed.adi2952

Marshall, B. P., Ashinsky, B. G., Ferrer, X. E., Kunes, J. A., Innis, A. C., Luzzi, A. J., Forrester, L. A., Burt, K. G., Lee, A. J., Song, L., Lisiewski, L. E., Soni, R. K., Hung, C. T., Levine, W. N., Kovacevic, D., & Thomopoulos, S. (2024). The subacromial bursa modulates tendon healing after rotator cuff injury in rats. Science Translational Medicine, 16(744). https://doi.org/10.1126/scitranslmed.add8273

Stokes, G., Li, Z., Talaba, N., Genthe, W., Brix, M. B., Pham, B., Wienhold, M. D., Sandok, G., Hernan, R., Wynn, J., Tang, H., Tabima, D. M., Rodgers, A., Hacker, T. A., Chesler, N. C., Zhang, P., Murad, R., Yuan, J. X.-J., Shen, Y., … McCulley, D. J. (2024). Rescuing lung development through embryonic inhibition of histone acetylation. Science Translational Medicine, 16(732). https://doi.org/10.1126/scitranslmed.adc8930

Borna, Š., Lee, E., Nideffer, J., Ramachandran, A., Wang, B., Baker, J., Mavers, M., Lakshmanan, U., Narula, M., Garrett, A. K., Schulze, J., Olek, S., Marois, L., Gernez, Y., Bhatia, M., Chong, H. J., Walter, J., Kitcharoensakkul, M., Lang, A., … Bacchetta, R. (2023). Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with FOXP3 mutations. Science Translational Medicine, 15(727). https://doi.org/10.1126/scitranslmed.adg6822

Tran, L. M., Macedo, C., Zahorchak, A. F., Gu, X., Elinoff, B., Singhi, A. D., Isett, B., Zeevi, A., Sykes, M., Breen, K., Srivastava, A., Ables, E. M., Landsittel, D., Styn, M. A., Humar, A., Lakkis, F. G., Metes, D. M., & Thomson, A. W. (2023). Donor-derived regulatory dendritic cell infusion modulates effector CD8 + T cell and NK cell responses after liver transplantation. Science Translational Medicine, 15(717). https://doi.org/10.1126/scitranslmed.adf4287

Liu, Y., Reiken, S., Dridi, H., Yuan, Q., Mohammad, K. S., Trivedi, T., Miotto, M. C., Wedderburn-Pugh, K., Sittenfeld, L., Kerley, Y., Meyer, J. A., Peters, J. S., Persohn, S. C., Bedwell, A. A., Figueiredo, L. L., Suresh, S., She, Y., Soni, R. K., Territo, P. R., … Guise, T. A. (2023). Targeting ryanodine receptor type 2 to mitigate chemotherapy-induced neurocognitive impairments in mice. Science Translational Medicine, 15(715). https://doi.org/10.1126/scitranslmed.adf8977

Qi, R., Sammler, E., Gonzalez-Hunt, C. P., Barraza, I., Pena, N., Rouanet, J. P., Naaldijk, Y., Goodson, S., Fuzzati, M., Blandini, F., Erickson, K. I., Weinstein, A. M., Lutz, M. W., Kwok, J. B., Halliday, G. M., Dzamko, N., Padmanabhan, S., Alcalay, R. N., Waters, C., … Sanders, L. H. (2023). A blood-based marker of mitochondrial DNA damage in Parkinson’s disease. Science Translational Medicine, 15(711). https://doi.org/10.1126/scitranslmed.abo1557

Guarnieri, J. W., Dybas, J. M., Fazelinia, H., Kim, M. S., Frere, J., Zhang, Y., Soto Albrecht, Y., Murdock, D. G., Angelin, A., Singh, L. N., Weiss, S. L., Best, S. M., Lott, M. T., Zhang, S., Cope, H., Zaksas, V., Saravia-Butler, A., Meydan, C., Foox, J., … Wallace, D. C. (2023). Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts. Science Translational Medicine, 15(708). https://doi.org/10.1126/scitranslmed.abq1533

Burn Aschner, C., Muthuraman, K., Kucharska, I., Cui, H., Prieto, K., Nair, M. S., Wang, M., Huang, Y., Christie-Holmes, N., Poon, B., Lam, J., Sultana, A., Kozak, R., Mubareka, S., Rubinstein, J. L., Rujas, E., Treanor, B., Ho, D. D., Jetha, A., & Julien, J.-P. (2023). A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo. Science Translational Medicine, 15(697). https://doi.org/10.1126/scitranslmed.adf4549

Tsai, C.-Y., Saito, T., Sarangdhar, M., Abu-El-Haija, M., Wen, L., Lee, B., Yu, M., Lipata, D. A., Manohar, M., Barakat, M. T., Contrepois, K., Tran, T. H., Theoret, Y., Bo, N., Ding, Y., Stevenson, K., Ladas, E. J., Silverman, L. B., Quadro, L., … Husain, S. Z. (2023). A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis. Science Translational Medicine, 15(687). https://doi.org/10.1126/scitranslmed.abn2110

Istvan, E. S., Guerra, F., Abraham, M., Huang, K.-S., Rocamora, F., Zhao, H., Xu, L., Pasaje, C., Kumpornsin, K., Luth, M. R., Cui, H., Yang, T., Palomo Diaz, S., Gomez-Lorenzo, M. G., Qahash, T., Mittal, N., Ottilie, S., Niles, J., Lee, M. C. S., … Winzeler, E. A. (2023). Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target. Science Translational Medicine, 15(686). https://doi.org/10.1126/scitranslmed.adc9249

Watanabe, H., Du, W., Son, J., Sui, L., Asahara, S., Kurland, I. J., Kuo, T., Kitamoto, T., Miyachi, Y., de Cabo, R., & Accili, D. (2023). Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes. Science Translational Medicine, 15(681). https://doi.org/10.1126/scitranslmed.abq4126

Qian, J., Guan, X., Xie, B., Xu, C., Niu, J., Tang, X., Li, C. H., Colecraft, H. M., Jaenisch, R., & Liu, X. S. (2023). Multiplex epigenome editing of MECP2 to rescue Rett syndrome neurons. Science Translational Medicine, 15(679). https://doi.org/10.1126/scitranslmed.add4666

Castillero, E., Fitzpatrick, E., Keeney, S. J., D’Angelo, A. M., Pressly, B. B., Simpson, M. T., Kurade, M., Erwin, W. C., Moreno, V., Camillo, C., Shukla, H. J., Inamdar, V. V., Aghali, A., Grau, J. B., Salvati, E., Nissim, I., Rauova, L., Oyama, M. A., Stachelek, S. J., … Ferrari, G. (2023). Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation. Science Translational Medicine, 15(677). https://doi.org/10.1126/scitranslmed.adc9606

Ostkamp, P., Deffner, M., Schulte-Mecklenbeck, A., Wünsch, C., Lu, I.-N., Wu, G. F., Goelz, S., De Jager, P. L., Kuhlmann, T., Gross, C. C., Klotz, L., Meyer zu Hörste, G., Wiendl, H., Schneider-Hohendorf, T., & Schwab, N. (2022). A single-cell analysis framework allows for characterization of CSF leukocytes and their tissue of origin in multiple sclerosis. Science Translational Medicine, 14(673). https://doi.org/10.1126/scitranslmed.adc9778

Shi, H., Wang, X., Li, F., Gerlach, B. D., Yurdagul, A., Moore, M. P., Zeldin, S., Zhang, H., Cai, B., Zheng, Z., Valenti, L., & Tabas, I. (2022). CD47-SIRPα axis blockade in NASH promotes necroptotic hepatocyte clearance by liver macrophages and decreases hepatic fibrosis. Science Translational Medicine, 14(672). https://doi.org/10.1126/scitranslmed.abp8309

Arendse, L. B., Murithi, J. M., Qahash, T., Pasaje, C. F. A., Godoy, L. C., Dey, S., Gibhard, L., Ghidelli-Disse, S., Drewes, G., Bantscheff, M., Lafuente-Monasterio, M. J., Fienberg, S., Wambua, L., Gachuhi, S., Coertzen, D., van der Watt, M., Reader, J., Aswat, A. S., Erlank, E., … Chibale, K. (2022). The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages. Science Translational Medicine, 14(667). https://doi.org/10.1126/scitranslmed.abo7219

Yrjölä, P., Myers, M. M., Welch, M. G., Stevenson, N. J., Tokariev, A., & Vanhatalo, S. (2022). Facilitating early parent-infant emotional connection improves cortical networks in preterm infants. Science Translational Medicine, 14(664). https://doi.org/10.1126/scitranslmed.abq4786

Frere, J. J., Serafini, R. A., Pryce, K. D., Zazhytska, M., Oishi, K., Golynker, I., Panis, M., Zimering, J., Horiuchi, S., Hoagland, D. A., Møller, R., Ruiz, A., Kodra, A., Overdevest, J. B., Canoll, P. D., Borczuk, A. C., Chandar, V., Bram, Y., Schwartz, R., … tenOever, B. R. (2022). SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery. Science Translational Medicine, 14(664). https://doi.org/10.1126/scitranslmed.abq3059

Liu, L., Iketani, S., Guo, Y., Reddem, E. R., Casner, R. G., Nair, M. S., Yu, J., Chan, J. F.-W., Wang, M., Cerutti, G., Li, Z., Morano, N. C., Castagna, C. D., Corredor, L., Chu, H., Yuan, S., Poon, V. K.-M., Chan, C. C.-S., Chen, Z., … Ho, D. D. (2022). An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses. Science Translational Medicine, 14(646). https://doi.org/10.1126/scitranslmed.abn6859

Mederacke, I., Filliol, A., Affo, S., Nair, A., Hernandez, C., Sun, Q., Hamberger, F., Brundu, F., Chen, Y., Ravichandra, A., Huebener, P., Anke, H., Shi, H., Martínez García de la Torre, R. A., Smith, J. R., Henderson, N. C., Vondran, F. W. R., Rothlin, C. V., Baehre, H., … Schwabe, R. F. (2022). The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver. Science Translational Medicine, 14(639). https://doi.org/10.1126/scitranslmed.abe5795

Joyce, M. G., King, H. A. D., Elakhal-Naouar, I., Ahmed, A., Peachman, K. K., Macedo Cincotta, C., Subra, C., Chen, R. E., Thomas, P. V., Chen, W.-H., Sankhala, R. S., Hajduczki, A., Martinez, E. J., Peterson, C. E., Chang, W. C., Choe, M., Smith, C., Lee, P. J., Headley, J. A., … Modjarrad, K. (2022). A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates. Science Translational Medicine, 14(632). https://doi.org/10.1126/scitranslmed.abi5735

Manigrasso, M. B., Rabbani, P., Egaña-Gorroño, L., Quadri, N., Frye, L., Zhou, B., Reverdatto, S., Ramirez, L. S., Dansereau, S., Pan, J., Li, H., D’Agati, V. D., Ramasamy, R., DeVita, R. J., Shekhtman, A., & Schmidt, A. M. (2021). Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice. Science Translational Medicine, 13(621). https://doi.org/10.1126/scitranslmed.abf7084