Department of Neurology
Grodstein, F., Yu, L., de Jager, P. L., Levey, A., Seyfried, N. T., & Bennett, D. A. (2022). Exploring cortical proteins underlying the relation of neuroticism to cognitive resilience. Aging Brain, 2, 100031. https://doi.org/10.1016/j.nbas.2022.100031
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Basavaraju, R., Guo, J., Small, S. A., Lieberman, J. A., Girgis, R. R., & Provenzano, F. A. (2022). Hippocampal Glutamate and Positive Symptom Severity in Clinical High Risk for Psychosis. JAMA Psychiatry, 79(2), 178. https://doi.org/10.1001/jamapsychiatry.2021.3710
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Couch, C. A., Gray, M. S., Shikany, J. M., Howard, V. J., Howard, G., Long, D. L., McClure, L. A., Manly, J. J., Cushman, M., Zakai, N. A., Pearson, K. E., Levitan, E. B., & Judd, S. E. (2021). Correlates of a southern diet pattern in a national cohort study of blacks and whites: the REasons for Geographic And Racial Differences in Stroke (REGARDS) study. British Journal of Nutrition, 126(12), 1904–1910. https://doi.org/10.1017/s0007114521000696
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Simoes, S., Guo, J., Buitrago, L., Qureshi, Y. H., Feng, X., Kothiya, M., Cortes, E., Patel, V., Kannan, S., Kim, Y. H., & Alzheimer's Disease Neuroimaging Initiative. (2021). Alzheimer's vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling. Cell Reports, 37(13), Article 110182. https://doi.org/10.1016/j.celrep.2021.110182
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Farooqi, N., Metherell, L. A., Schrauwen, I., Acharya, A., Khan, Q., Nouel Saied, L. M., Ali, Y., El-Serehy, H. A., Jalil, F., & Leal, S. M. (2021). Exome Sequencing Identifies a Novel FBN1 Variant in a Pakistani Family with Marfan Syndrome That Includes Left Ventricle Diastolic Dysfunction. Genes, 12(12), 1915. https://doi.org/10.3390/genes12121915
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Gu, Y., Nishikawa, M., Brickman, A. M., Manly, J. J., Schupf, N., & Mayeux, R. P. (2021). Association of Dietary Prebiotic Consumption with Reduced Risk of Alzheimer’s Disease in a Multiethnic Population. Current Alzheimer Research, 18(12), 984–992. https://doi.org/10.2174/1567205019666211222115142
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Vagelos College of Physicians and Surgeons; Department of Medicine; NewYork-Presbyterian Allen Hospital; Department of Radiology; Department of Neurology; Department of Psychiatry; Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; Gertrude H. Sergievsky Center; Department of Epidemiology; Mailman School of Public Health
Song, S., Stern, Y., & Gu, Y. (2022). Modifiable lifestyle factors and cognitive reserve: A systematic review of current evidence. Ageing Research Reviews, 74, 101551. https://doi.org/10.1016/j.arr.2021.101551
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Vogelbaum, M. A., Brown, P. D., Messersmith, H., Brastianos, P. K., Burri, S., Cahill, D., Dunn, I. F., Gaspar, L. E., Gatson, N. T. N., Gondi, V., Jordan, J. T., Lassman, A. B., Maues, J., Mohile, N., Redjal, N., Stevens, G., Sulman, E., van den Bent, M., Wallace, H. J., … Schiff, D. (2021). Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline. Neuro-Oncology, 24(3), 331–357. https://doi.org/10.1093/neuonc/noab262
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Morris, N. A., Mazzeffi, M., McArdle, P., May, T. L., Waldrop, G., Perman, S. M., Burke, J. F., Bradley, S. M., Agarwal, S., Figueroa, J. F., & Badjatia, N. (2021). Hispanic/Latino‐Serving Hospitals Provide Less Targeted Temperature Management Following Out‐of‐Hospital Cardiac Arrest. Journal of the American Heart Association, 10(24). https://doi.org/10.1161/jaha.121.023934
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Maraki, M. I., Hatzimanolis, A., Mourtzi, N., Stefanis, L., Yannakoulia, M., Kosmidis, M. H., Dardiotis, E., Hadjigeorgiou, G. M., Sakka, P., Ramirez, A., Grenier-Boley, B., Lambert, J.-C., Heilmann-Heimbach, S., Stamelou, M., Scarmeas, N., & Xiromerisiou, G. (2021). Association of the Polygenic Risk Score With the Probability of Prodromal Parkinson’s Disease in Older Adults. Frontiers in Molecular Neuroscience, 14. https://doi.org/10.3389/fnmol.2021.739571
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Storm, C. S., Kia, D. A., Almramhi, M. M., Bandres-Ciga, S., Finan, C., Noyce, A. J., Kaiyrzhanov, R., Middlehurst, B., Tan, M., Houlden, H., Morris, H. R., Plun-Favreau, H., Holmans, P., Hardy, J., Trabzuni, D., Quinn, J., Bubb, V., Mok, K. Y., … Wood, N. W. (2021). Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-26280-1
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Post, M. R., Lee, W.-L., Guo, J., Sames, D., & Sulzer, D. (2021). Development of a Dual Fluorescent and Magnetic Resonance False Neurotransmitter That Reports Accumulation and Release from Dopaminergic Synaptic Vesicles. ACS Chemical Neuroscience, 12(24), 4546–4553. https://doi.org/10.1021/acschemneuro.1c00580
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Zoghbi, A. W., Dhindsa, R. S., Goldberg, T. E., Mehralizade, A., Motelow, J. E., Wang, X., Alkelai, A., Harms, M. B., Lieberman, J. A., Markx, S., & Goldstein, D. B. (2021). High-impact rare genetic variants in severe schizophrenia. Proceedings of the National Academy of Sciences, 118(51). https://doi.org/10.1073/pnas.2112560118
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Juneja, P. (2021). COVID‐19 humanised med school: Let us keep it that way. The Clinical Teacher, 19(1), 57–58. Portico. https://doi.org/10.1111/tct.13447
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Charisis, S., Ntanasi, E., Yannakoulia, M., Anastasiou, C. A., Kosmidis, M. H., Dardiotis, E., Gargalionis, A. N., Patas, K., Chatzipanagiotou, S., Mourtzinos, I., Tzima, K., Hadjigeorgiou, G., Sakka, P., Kapogiannis, D., & Scarmeas, N. (2021). Diet Inflammatory Index and Dementia Incidence. Neurology, 97(24). https://doi.org/10.1212/wnl.0000000000012973
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Graham, S. E., Clarke, S. L., Wu, K.-H. H., Kanoni, S., Zajac, G. J. M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Hwang, M. Y., Han, S., Narita, A., Choudhury, A., Bentley, A. R., Ekoru, K., Verma, A., … Willer, C. J. (2021). The power of genetic diversity in genome-wide association studies of lipids. Nature, 600(7890), 675–679. https://doi.org/10.1038/s41586-021-04064-3
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Mehta, P., Raymond, J., Han, M. K., Larson, T., Berry, J. D., Paganoni, S., Mitsumoto, H., Bedlack, R. S., & Horton, D. K. (2021). Recruitment of Patients With Amyotrophic Lateral Sclerosis for Clinical Trials and Epidemiological Studies: Descriptive Study of the National ALS Registry’s Research Notification Mechanism. Journal of Medical Internet Research, 23(12), e28021. https://doi.org/10.2196/28021
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Roostaei, T., Klein, H.-U., Ma, Y., Felsky, D., Kivisäkk, P., Connor, S. M., Kroshilina, A., Yung, C., Kaskow, B. J., Shao, X., Rhead, B., Ordovás, J. M., Absher, D. M., Arnett, D. K., Liu, J., Patsopoulos, N., Barcellos, L. F., Weiner, H. L., & De Jager, P. L. (2021). Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-27427-w
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Miller, E. C., Wilczek, A., Bello, N. A., Tom, S., Wapner, R., & Suh, Y. (2022). Pregnancy, preeclampsia and maternal aging: From epidemiology to functional genomics. Ageing Research Reviews, 73, 101535. https://doi.org/10.1016/j.arr.2021.101535
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Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Neurology; Division of Stroke and Cerebrovascular Disease; Department of Obstetrics and Gynecology; Department of Genetics and Development; Department of Medicine; Seymour, Paul, and Gloria Milstein Division of Cardiology; Mailman School of Public Health; Department of Epidemiology
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Miltiades, A., Houck, P. J., Monteleone, M., Harrison, N. L., Cabrera-Garcia, D., Roh, D., & Wagener, G. (2021). Insights into Fibrinogen-Mediated COVID-19 Hypercoagubility in Critically Ill Patients. Journal of Neurosurgical Anesthesiology, 34(1), 136–140. https://doi.org/10.1097/ana.0000000000000812
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Bassil, D. T., Farrell, M. T., Wagner, R. G., Brickman, A. M., Glymour, M. M., Langa, K. M., Manly, J. J., Salinas, J., Tipping, B., Tollman, S., & Berkman, L. F. (2021). Cohort Profile Update: Cognition and dementia in the Health and Aging in Africa Longitudinal Study of an INDEPTH community in South Africa (HAALSI dementia). International Journal of Epidemiology, 51(4), e217–e226. https://doi.org/10.1093/ije/dyab250
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McNally, E. M., Elkind, M. S. V., Benjamin, I. J., Chung, M. K., Dillon, G. H., Hernandez, A. F., Ibeh, C., Lloyd-Jones, D. M., McCullough, L. D., Wold, L. E., Wright, D. R., & Wu, J. C. (2021). Impact of the COVID-19 Pandemic on Cardiovascular Science: Anticipating Problems and Potential Solutions: A Presidential Advisory From the American Heart Association. Circulation, 144(23). https://doi.org/10.1161/cir.0000000000001027
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Ardalan, A., Yamane, N., Rao, A. K., Montes, J., & Goldman, S. (2021). Analysis of gait synchrony and balance in neurodevelopmental disorders using computer vision techniques. Health Informatics Journal, 27(4). https://doi.org/10.1177/14604582211055650
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Witsch, J., Roh, D. J., Avadhani, R., Merkler, A. E., Kamel, H., Awad, I., Hanley, D. F., Ziai, W. C., & Murthy, S. B. (2021). Association Between Intraventricular Alteplase Use and Parenchymal Hematoma Volume in Patients With Spontaneous Intracerebral Hemorrhage and Intraventricular Hemorrhage. JAMA Network Open, 4(12), e2135773. https://doi.org/10.1001/jamanetworkopen.2021.35773
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Ma, Y., Dammer, E. B., Felsky, D., Duong, D. M., Klein, H.-U., White, C. C., Zhou, M., Logsdon, B. A., McCabe, C., Xu, J., Wang, M., Wingo, T. S., Lah, J. J., Zhang, B., Schneider, J., Allen, M., Wang, X., Ertekin-Taner, N., Seyfried, N. T., … De Jager, P. L. (2021). Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-27204-9
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Ranard, B. L., Megjhani, M., Terilli, K., Doyle, K., Claassen, J., Pinsky, M. R., Clermont, G., Vodovotz, Y., Asgari, S., & Park, S. (2021). Identification of Endotypes of Hospitalized COVID-19 Patients. Frontiers in Medicine, 8. https://doi.org/10.3389/fmed.2021.770343
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Lopez-Navarro, E. R., & Gutierrez, J. (2021). Metalloproteinases and their inhibitors in neurological disease. Naunyn-Schmiedeberg’s Archives of Pharmacology, 395(1), 27–38. https://doi.org/10.1007/s00210-021-02188-x
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Yap, Z. Y., Efthymiou, S., Seiffert, S., Vargas Parra, K., Lee, S., Nasca, A., Maroofian, R., Schrauwen, I., Pendziwiat, M., Jung, S., Bhoj, E., Striano, P., Mankad, K., Vona, B., Cuddapah, S., Wagner, A., Alvi, J. R., Davoudi-Dehaghani, E., Fallah, M.-S., … Yoon, W. H. (2021). Bi-allelic variants in OGDHL cause a neurodevelopmental spectrum disease featuring epilepsy, hearing loss, visual impairment, and ataxia. The American Journal of Human Genetics, 108(12), 2368–2384. https://doi.org/10.1016/j.ajhg.2021.11.003
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Goldman, J. G., Boeve, B. F., Armstrong, M. J., Galasko, D. R., Galvin, J. E., Irwin, D. J., Leverenz, J. B., Marder, K., Abler, V., Biglan, K., Irizarry, M. C., Keller, B., Lai, R., Munsie, L., Belleville, M., Chaney, O., Richard, I., Taylor, A., & Graham, T. (2021). Lewy Body Dementia Association’s Industry Advisory Council: proceedings of the second annual meeting. Alzheimer’s Research & Therapy, 13(1). https://doi.org/10.1186/s13195-021-00868-7
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Yu, T.-S., Tensaouti, Y., Stephanz, E. P., Chintamen, S., Rafikian, E. E., Yang, M., & Kernie, S. G. (2021). Astrocytic ApoE underlies maturation of hippocampal neurons and cognitive recovery after traumatic brain injury in mice. Communications Biology, 4(1). https://doi.org/10.1038/s42003-021-02841-4
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Hu, W. T., Ozturk, T., Kollhoff, A., Wharton, W., Christina Howell, J., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Perrin, R. J., Shaw, L. M., … Chiang, G. (2021). Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-24220-7
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Seo, B. A., Kim, D., Hwang, H., Kim, M. S., Ma, S.-X., Kwon, S.-H., Kweon, S. H., Wang, H., Yoo, J. M., Choi, S., Kwon, S. H., Kang, S.-U., Kam, T.-I., Kim, K., Karuppagounder, S. S., Kang, B. G., Lee, S., Park, H., Kim, S., … Ko, H. S. (2021). TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease. Neuron, 109(23), 3758-3774.e11. https://doi.org/10.1016/j.neuron.2021.09.031
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Wojnarowicz, P. M., Escolano, M. G., Huang, Y.-H., Desai, B., Chin, Y., Shah, R., Xu, S., Yadav, S., Yaklichkin, S., Ouerfelli, O., Soni, R. K., Philip, J., Montrose, D. C., Healey, J. H., Rajasekhar, V. K., Garland, W. A., Ratiu, J., Zhuang, Y., Norton, L., … Benezra, R. (2021). Anti-tumor effects of an ID antagonist with no observed acquired resistance. Npj Breast Cancer, 7(1). https://doi.org/10.1038/s41523-021-00266-0
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Shiau, S., Arpadi, S. M., Shen, Y., Cantos, A., Ramon, C. V., Shah, J., Jang, G., Manly, J. J., Brickman, A. M., Baccarelli, A. A., & Yin, M. T. (2021). Epigenetic Aging Biomarkers Associated With Cognitive Impairment in Older African American Adults With Human Immunodeficiency Virus (HIV). Clinical Infectious Diseases, 73(11), 1982–1991. https://doi.org/10.1093/cid/ciab563
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Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Medicine; Division of Infectious Diseases; Gertrude H. Sergievsky Center; Department of Pediatrics; Mailman School of Public Health; Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; Department of Neurology; Department of Environmental Health Sciences
Jones, G., Trajanoska, K., Santanasto, A. J., Stringa, N., Kuo, C.-L., Atkins, J. L., Lewis, J. R., Duong, T., Hong, S., Biggs, M. L., Luan, J., Sarnowski, C., Lunetta, K. L., Tanaka, T., Wojczynski, M. K., Cvejkus, R., Nethander, M., Ghasemi, S., Yang, J., … Pilling, L. C. (2021). Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-20918-w
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Grancharova, T., Gerbin, K. A., Rosenberg, A. B., Roco, C. M., Arakaki, J. E., DeLizo, C. M., Dinh, S. Q., Donovan-Maiye, R. M., Hirano, M., Nelson, A. M., Tang, J., Theriot, J. A., Yan, C., Menon, V., Palecek, S. P., Seelig, G., & Gunawardane, R. N. (2021). A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-94732-1
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Lazar, R. M., Wadley, V. G., Myers, T., Jones, M. R., Heck, D. V., Clark, W. M., Marshall, R. S., Howard, V. J., Voeks, J. H., Manly, J. J., Moy, C. S., Chaturvedi, S., Meschia, J. F., Lal, B. K., Brott, T. G., & Howard, G. (2021). Baseline Cognitive Impairment in Patients With Asymptomatic Carotid Stenosis in the CREST-2 Trial. Stroke, 52(12), 3855–3863. https://doi.org/10.1161/strokeaha.120.032972
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Singhania, A., Pham, J., Dhanwani, R., Frazier, A., Rezende Dutra, J., Marder, K. S., Phillips, E., Mallal, S., Amara, A. W., Standaert, D. G., Sulzer, D., Peters, B., Sette, A., & Lindestam Arlehamn, C. S. (2021). The TCR repertoire of α-synuclein-specific T cells in Parkinson’s disease is surprisingly diverse. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-020-79726-9
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Nguyen, T. T. T., Shang, E., Shu, C., Kim, S., Mela, A., Humala, N., Mahajan, A., Yang, H. W., Akman, H. O., Quinzii, C. M., Zhang, G., Westhoff, M.-A., Karpel-Massler, G., Bruce, J. N., Canoll, P., & Siegelin, M. D. (2021). Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-25501-x
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Guo, J., Brickman, A. M., Manly, J. J., Reitz, C., Schupf, N., Mayeux, R. P., & Gu, Y. (2021). Association of Life’s Simple 7 with incident dementia and its modification by the apolipoprotein E genotype. Alzheimer’s & Dementia, 17(12), 1905–1913. Portico. https://doi.org/10.1002/alz.12359
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Bravo, C. A., Fried, J. A., Willey, J. Z., Javaid, A., Mondellini, G. M., Braghieri, L., Lumish, H., Topkara, V. K., Kaku, Y., Witer, L., Takayama, H., Takeda, K., Sayer, G., Uriel, N., Demmer, R. T., Naka, Y., Yuzefpolskaya, M., & Colombo, P. C. (2021). Presence of Intracardiac Thrombus at the Time of Left Ventricular Assist Device Implantation Is Associated With an Increased Risk of Stroke and Death. Journal of Cardiac Failure, 27(12), 1367–1373. https://doi.org/10.1016/j.cardfail.2021.06.011
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Kokkonen, H., Siren, A., Määttä, T., Kamila Kadlubowska, M., Acharya, A., Nouel‐Saied, L. M., Leal, S. M., Järvelä, I., & Schrauwen, I. (2021). Identification of microduplications at Xp21.2 and Xq13.1 in neurodevelopmental disorders. Molecular Genetics & Genomic Medicine, 9(12). Portico. https://doi.org/10.1002/mgg3.1703
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Huang, Y., Sun, X., Jiang, H., Yu, S., Robins, C., Armstrong, M. J., Li, R., Mei, Z., Shi, X., Gerasimov, E. S., De Jager, P. L., Bennett, D. A., Wingo, A. P., Jin, P., Wingo, T. S., & Qin, Z. S. (2021). A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer’s disease. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-24710-8
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Bajorek, L. P., Kiekhofer, R., Hall, M., Taylor, J., Lucente, D. E., Brushaber, D., Appleby, B., Coppolla, G., Bordelon, Y. M., Botha, H., Dickerson, B. C., Dickson, D. W., Domoto‐Reilly, K., Fagan, A. M., Fields, J. A., Fong, J. C., Foroud, T. M., Forsberg, L. K., … Galasko, D. R. (2021). Demographic and psychosocial factors associated with the decision to learn mutation status in familial frontotemporal dementia and the impact of disclosure on mood. Alzheimer’s & Dementia, 17(S7). Portico. https://doi.org/10.1002/alz.050692
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Gionco, J. T., Hartstone, W. G., Martuscello, R. T., Kuo, S.-H., Faust, P. L., & Louis, E. D. (2021). Essential Tremor versus “ET-plus”: A Detailed Postmortem Study of Cerebellar Pathology. The Cerebellum, 20(6), 904–912. https://doi.org/10.1007/s12311-021-01263-6
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Borkowski, K., Taha, A. Y., Pedersen, T. L., De Jager, P. L., Bennett, D. A., Arnold, M., Kaddurah-Daouk, R., & Newman, J. W. (2021). Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-98640-2
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Lee, H., Tzuang, M., Tee, B. L., Li, C., Gu, Y., Lu, A. T., Lee, S. A., Seo, E. H., Kang, Y., Kim, K., Tran, B., Chae, W., Nguyen, D., Nguyen, D., Vuong, Q., Jun, G. R., Wang, L., Yu, W. H., & Park, V. T. (2021). Using a multi‐staged translation method to develop socio‐culturally and language‐sensitive study materials: Lessons learned from an Asian cohort for Alzheimer’s disease. Alzheimer’s & Dementia, 17(S10). Portico. https://doi.org/10.1002/alz.054440
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Chesebro, A. G., Amarante, E., Lao, P. J., Meier, I. B., Mayeux, R., & Brickman, A. M. (2021). Automated detection of cerebral microbleeds on T2*-weighted MRI. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-83607-0
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McDonnell, E. I., Wang, Y., Goldman, J., & Marder, K. (2021). Age of Onset of Huntington’s Disease in Carriers of Reduced Penetrance Alleles. Movement Disorders, 36(12), 2958–2961. Portico. https://doi.org/10.1002/mds.28789
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Andersen, S., Rizer, S., Souci, L. S., Berlin, M., Harris, E., Cosentino, S., Sebastiani, P., & Perls, T. (2021). Longevity Studies in the New Normal: The Move to Virtual Assessment. Innovation in Aging, 5(Supplement_1), 136–136. https://doi.org/10.1093/geroni/igab046.526
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