TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease

Seo, B. A., Kim, D., Hwang, H., Kim, M. S., Ma, S.-X., Kwon, S.-H., Kweon, S. H., Wang, H., Yoo, J. M., Choi, S., Kwon, S. H., Kang, S.-U., Kam, T.-I., Kim, K., Karuppagounder, S. S., Kang, B. G., Lee, S., Park, H., Kim, S., … Ko, H. S. (2021). TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease. Neuron, 109(23), 3758-3774.e11. https://doi.org/10.1016/j.neuron.2021.09.031
Authors:
Bo Am Seo
Donghoon Kim
Heehong Hwang
Min Seong Kim
Shi-Xun Ma
Seung-Hwan Kwon
Sin Ho Kweon
Hu Wang
Je Min Yoo
Seulah Choi
Sang Ho Kwon
Sung-Ung Kang
Tae-In Kam
Kwangsoo Kim
Senthilkumar S. Karuppagounder
Bong Gu Kang
Saebom Lee
Hyejin Park
Sangjune Kim
Wei Yan
Yong-Shi Li
Sheng-Han Kuo
Javier Redding-Ochoa
Olga Pletnikova
Juan C. Troncoso
Gabsang Lee
Xiaobo Mao
Valina L. Dawson
Ted M. Dawson
Han Seok Ko
Affiliated Authors:
Yong-Shi Li
Sheng-Han Kuo
Columbia Affiliation:
Author Keywords:
gaucher's disease (gd)
glucocerebrosidase (gcase)
glucocerebrosidase 1 gene (gba1)
glucosylceramide (glccer)
lysosome
mitochondria
parkinson's disease (pd)
thyroid hormone receptor interacting protein 12 (trip12)
α-synuclein
α-synuclein preformed fibrils (α-syn pffs)
elink
Publication Type:
Article
Unique ID:
10.1016/j.neuron.2021.09.031
PMID:
34644545
DOI:
10.1016/j.neuron.2021.09.031
Journal:
Neuron
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View Web of Science Record

Record Created: