Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome

Storm, C. S., Kia, D. A., Almramhi, M. M., Bandres-Ciga, S., Finan, C., Noyce, A. J., Kaiyrzhanov, R., Middlehurst, B., Tan, M., Houlden, H., Morris, H. R., Plun-Favreau, H., Holmans, P., Hardy, J., Trabzuni, D., Quinn, J., Bubb, V., Mok, K. Y., … Wood, N. W. (2021). Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-26280-1
Authors:
Catherine S. Storm
Demis A. Kia
Mona Mohammad Almramhi
Sara Bandrés‐Ciga
Chris Finan
Alastair Noyce
Rauan Kaiyrzhanov
Ben Middlehurst
Manuela Tan
Henry Houlden
Huw R. Morris
Hélène Plun‐Favreau
Peter Holmans
John Hardy
Daniah Trabzuni
John P. Quinn
Vivien J. Bubb
Kin Y. Mok
Kerri J. Kinghorn
Patrick A. Lewis
Sebastian R. Schreglmann
Ruth C. Lovering
Lea R’Bibo
Claudia Manzoni
Mie Rizig
Mina Ryten
Sebastian Guelfi
Valentina Escott‐Price
Viorica Chelban
Thomas Foltynie
Nigel Williams
Karen Morrison
Carl E Clarke
Kirsten Harvey
Benjamin Meir Jacobs
Alexis Brice
Alexis Brice
Suzanne Lesage
Jean‐Christophe Corvol
María Martínez
Claudia Schulte
Kathrin Brockmann
Javier Simón‐Sánchez
Peter Heutink
Patrizia Rizzu
Manu Sharma
Thomas Gasser
Susanne A. Schneider
Mark Cookson
Cornelis Blauwendraat
David W. Craig
Kimberley Billingsley
Mary B. Makarious
Derek P. Narendra
Faraz Faghri
J. Raphael Gibbs
Dena Hernández
Kendall Van Keuren‐Jensen
Joshua Shulman
Hirotaka Iwaki
Hampton L. Leonard
Mike A. Nalls
Laurie Robak
José Brás
Rita Guerreiro
Steven Lubbe
Timothy Troycoco
Steven Finkbeiner
Niccolò E. Mencacci
Codrin Lungu
Andrew Singleton
Sonja W. Scholz
Xylena Reed
Ryan J. Uitti
Owen A. Ross
Francis P. Grenn
Anni Moore
Roy N. Alcalay
Zbigniew K. Wszołek
Ziv Gan‐Or
Guy A. Rouleau
Lynne Krohn
Kheireddin Mufti
Jacobus J. van Hilten
Johan Marinus
Astrid D. Adarmes-Gómez
Miquel Aguilar
Ignacio Álvarez
Victoria Álvarez
Francisco Javier Barrero
Jesús Alberto Bergareche Yarza
Inmaculada Bernal‐Bernal
Marta Blázquez Estrada
Marta Bonilla‐Toribio
Juan A. Botía
María Teresa Boungiorno
Dolores Buiza‐Rueda
Ana Cámara
Fátima Carrillo
Mario Carrión‐Claro
Affiliated Authors:
Roy N. Alcalay
Columbia Affiliation:
Subjects:
Genomic Studies and Association Analyses (OpenAlex Topic)
Analysis of Gene Interaction Networks (OpenAlex Topic)
Genomic Rearrangements and Copy Number Variations (OpenAlex Topic)
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Publication Type:
Article
Unique ID:
10.1038/s41467-021-26280-1
PMID:
34930919
DOI:
10.1038/s41467-021-26280-1
Journal:
Nature Communications
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
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