T1D patient-derived hematopoietic stem cells are programmed to generate Tph, Tfh, and autoimmunity-associated B cell subsets in human immune system mice

Vecchione, A., Madley, R., Danzl, N., Borsotti, C., Marharlooei, M. K., Li, H.-W., Nauman, G., Ding, X., Ho, S.-H., Fousteri, G., & Sykes, M. (2022). T1D patient-derived hematopoietic stem cells are programmed to generate Tph, Tfh, and autoimmunity-associated B cell subsets in human immune system mice. Clinical Immunology, 240, 109048. https://doi.org/10.1016/j.clim.2022.109048
Authors:
Andrea Vecchione
Rachel Madley
Nichole Danzl
Chiara Borsotti
Mohsen Khosravi Marharlooei
Hao-Wei Li
Grace Nauman
Xiaolan Ding
Siu-Hong Ho
Georgia Fousteri
Megan Sykes
Affiliated Authors:
Andrea Vecchione
Rachel Madley
Nichole Danzl
Chiara Borsotti
Mohsen Khosravi Marharlooei
Hao-Wei Li
Grace Nauman
Xiaolan Ding
Siu-Hong Ho
Megan Sykes
Columbia Affiliation:
Subjects:
B-Lymphocyte Subsets (MeSH)
Diabetes Mellitus, Type 1 (MeSH)
Author Keywords:
type 1 diabetes
t helper follicular cell
t peripheral helper cell
b cell
autoreactive
autoantibodies
personalized immune mice
human immune system mice
hematopoietic stem cells
autoimmunity
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Publication Type:
Article
Unique ID:
10.1016/j.clim.2022.109048
PMID:
35644520
DOI:
10.1016/j.clim.2022.109048
Journal:
Clinical Immunology
Publication Date:
Data Source:
Scopus
Source Link:
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Record Created: