Immunoglobulin G

Subject Vocabulary
MeSH
Unique ID
D007074

Development of high-titer class-switched antibody responses to phosphorylated amino acids is prevalent in pancreatic ductal adenocarcinoma

Aguiar, T., Mashiko, S., Asam, K., Roy, P., Wang, S., Frank, K., Dietzel, M., Schahadat, L. G. Z., Ausmeier, M., Hertel, A., Duan, Z. R. S., Aouizerat, B., Genkinger, J. M., Remotti, H., & Zorn, E. (2025). Development of high-titer class-switched antibody responses to phosphorylated amino acids is prevalent in pancreatic ductal adenocarcinoma. Frontiers in Immunology, 16. https://doi.org/10.3389/fimmu.2025.1501943
Authors:
Talita Ferreira Marques Aguiar
Shunya Mashiko
Kesava Asam
Poulomi Roy
Shikun Wang
Katharina Frank
Max Dietzel
Luca G. Z. Schahadat
Mattea Ausmeier
A. Hertel
Zhijian Duan
Bradley E. Aouizerat
Jeanine M. Genkinger
Helen Remotti
Emmanuel Zorn
Affiliated Authors:
Talita Ferreira Marques Aguiar
Shunya Mashiko
Poulomi Roy
Shikun Wang
Katharina Frank
Max Dietzel
Luca G. Z. Schahadat
Mattea Ausmeier
A. Hertel
Zhijian Duan
Jeanine M. Genkinger
Emmanuel Zorn
Columbia Affiliation:
Subjects:
Carcinoma, Pancreatic Ductal (MeSH)
Pancreatic Neoplasms (MeSH)
Immunoglobulin G (MeSH)
Antibody Formation (MeSH)
Amino Acids (MeSH)
Therapeutic Antibodies: Development, Engineering, and Applications (OpenAlex Topic)
Glycosylation in Health and Disease (OpenAlex Topic)
Epidemiology and Management of Neuroendocrine Tumors (OpenAlex Topic)
Author Keywords:
pancreatic ductal adenocarcinoma
antibody responses
phosphoryl adducts
phosphoproteome
elisa
Publication Type:
Article
Unique ID:
10.3389/fimmu.2025.1501943
PMID:
40226613
DOI:
10.3389/fimmu.2025.1501943
Journal:
Frontiers in Immunology
Publication Date:
Data Source:
OpenAlex
Source Link:
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Infiltrating plasma cells maintain glioblastoma stem cells through IgG-Tumor binding

Gao, J., Gu, D., Yang, K., Zhang, J., Lin, Q., Yuan, W., Zhu, X., Dixit, D., Gimple, R. C., You, H., Zhang, Q., Shi, Z., Fan, X., Wu, Q., Lu, C., Cheng, Z., Li, D., Zhao, L., Xue, B., … Wang, X. (2025). Infiltrating plasma cells maintain glioblastoma stem cells through IgG-Tumor binding. Cancer Cell, 43(1), 122-143.e8. https://doi.org/10.1016/j.ccell.2024.12.006
Authors:
Jiancheng Gao
Danling Gu
Kailin Yang
Junxia Zhang
Qiankun Lin
Wei Yuan
Xu Zhu
Deobrat Dixit
Ryan C Gimple
Hao You
Qian Zhang
Zhumei Shi
Xiao Fan
Qiulian Wu
Chenfei Lu
Zhangchun Cheng
Daqi Li
Linjie Zhao
Bin Xue
Zhu Zhu
Zhe Zhu
Hui Yang
Ningwei Zhao
Wei Gao
Yingmei Lu
Junfei Shao
Chuandong Cheng
Dapeng Hao
Shuo Yang
Yun Chen
Xiaoming Wang
Chunsheng Kang
Jing Ji
Jianghong Man
Sameer Agnihotri
Qianghu Wang
Fan Lin
Xu Qian
Stephen C Mack
Zhibin Hu
Chaojun Li
Michael D Taylor
Yan Li
Nu Zhang
Jeremy N Rich
Yongping You
Xiuxing Wang
Affiliated Authors:
Zhe Zhu
Columbia Affiliation:
Subjects:
Glioblastoma (MeSH)
Neoplastic Stem Cells (MeSH)
Plasma Cells (MeSH)
Immunoglobulin G (MeSH)
Brain Neoplasms (MeSH)
Author Keywords:
fcγriia
glioblastoma
glioblastoma stem cell
plasma cell
single-cell b cell receptor-seq
single-cell rna-seq
immunoglobulin g
isoflurane
luciferin
protein kinase b
receptors, igg
spectrum ct
b lymphocyte receptor
chemokine receptor ccr2
fc receptor iia
mammalian target of rapamycin
monocyte chemotactic protein 1
fc receptor
adult
aged
akt/mtor signaling
animal cell
animal experiment
animal model
animal tissue
article
b lymphocyte
cancer growth
cancer prognosis
cancer stem cell
carcinogenesis
cell proliferation
controlled study
embryo
female
human
human cell
human tissue
immunoglobulin production
male
middle aged
nonhuman
paracrine signaling
receptor blocking
signal transduction
single cell rna seq
somatic hypermutation
stem cell self-renewal
tumor associated leukocyte
animal
brain tumor
genetics
immunology
metabolism
mouse
pathology
tumor cell line
tumor microenvironment
animals
brain neoplasms
cell line, tumor
humans
mice
neoplastic stem cells
plasma cells
Publication Type:
Article
Unique ID:
10.1016/j.ccell.2024.12.006
PMID:
39753140
DOI:
10.1016/j.ccell.2024.12.006
Journal:
Cancer Cell
Publication Date:
Data Source:
PubMed
Source Link:
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Nipocalimab in Early-Onset Severe Hemolytic Disease of the Fetus and Newborn

Moise, K. J., Ling, L. E., Oepkes, D., Tiblad, E., Verweij, E. J. T. J., Lopriore, E., Smoleniec, J., Sachs, U. J., Bein, G., Kilby, M. D., Miller, R. S., Devlieger, R., Audibert, F., Emery, S. P., Markham, K., Norton, M. E., Ocón-Hernández, O., Pandya, P., Pereira, L., … Bussel, J. B. (2024). Nipocalimab in Early-Onset Severe Hemolytic Disease of the Fetus and Newborn. New England Journal of Medicine, 391(6), 526–537. https://doi.org/10.1056/nejmoa2314466
Authors:
Kenneth J Moise
Leona E Ling
Dick Oepkes
Eleonor Tiblad
E J T Joanne Verweij
Enrico Lopriore
John Smoleniec
Ulrich J Sachs
Gregor Bein
Mark D Kilby
Russell S Miller
Roland Devlieger
François Audibert
Stephen P Emery
Kara Markham
Mary E Norton
Olga Ocón-Hernández
Pranav Pandya
Leonardo Pereira
Robert M Silver
Rory Windrim
James B Streisand
Jocelyn H Leu
Arpana Mirza
Valerie Smith
Lisa B Schwartz
May Lee Tjoa
Shumyla Saeed-Khawaja
Yosuke Komatsu
James B Bussel
Affiliated Authors:
Kenneth J Moise
Leona E Ling
Dick Oepkes
Eleonor Tiblad
E J T Joanne Verweij
Enrico Lopriore
John Smoleniec
Ulrich J Sachs
Gregor Bein
Mark D Kilby
Russell S Miller
Roland Devlieger
François Audibert
Stephen P Emery
Kara Markham
Mary E Norton
Olga Ocón-Hernández
Pranav Pandya
Leonardo Pereira
Robert M Silver
Rory Windrim
James B Streisand
Jocelyn H Leu
Arpana Mirza
Valerie Smith
Lisa B Schwartz
May Lee Tjoa
Shumyla Saeed-Khawaja
Yosuke Komatsu
James B Bussel
Columbia Affiliation:
Subjects:
Antibodies, Monoclonal, Humanized (MeSH)
Erythroblastosis, Fetal (MeSH)
Immunoglobulin G (MeSH)
Isoantibodies (MeSH)
Hydrops Fetalis (MeSH)
Publication Type:
Article
Unique ID:
10.1056/nejmoa2314466
PMID:
39115062
DOI:
10.1056/nejmoa2314466
Journal:
New England Journal of Medicine
Publication Date:
Data Source:
PubMed
Source Link:
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Novel approaches beyond standard immunofluorescence for kidney biopsies

Santoriello, D., & Nasr, S. H. (2022). Novel approaches beyond standard immunofluorescence for kidney biopsies. Current Opinion in Nephrology & Hypertension, 31(3), 221–227. https://doi.org/10.1097/mnh.0000000000000783
Authors:
Dominick Santoriello
Samih H Nasr
Affiliated Authors:
Dominick Santoriello
Columbia Affiliation:
Subjects:
Glomerulonephritis (MeSH)
Immunoglobulin G (MeSH)
Publication Type:
Article
Unique ID:
10.1097/mnh.0000000000000783
PMID:
35256574
DOI:
10.1097/mnh.0000000000000783
Journal:
Current Opinion in Nephrology and Hypertension
Publication Date:
Data Source:
PubMed
Source Link:
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Small intestinal immunopathology and GI-associated antibody formation in hereditary alpha-tryptasemia

Konnikova, L., Robinson, T. O., Owings, A. H., Shirley, J. F., Davis, E., Tang, Y., Wall, S., Li, J., Hasan, M. H., Gharaibeh, R. Z., Mendoza Alvarez, L. B., Ryan, L. K., Doty, A., Chovanec, J. F., O’Connell, M. P., Grunes, D. E., Daley, W. P., Mayer, E., Chang, L., … Lyons, J. J. (2021). Small intestinal immunopathology and GI-associated antibody formation in hereditary alpha-tryptasemia. Journal of Allergy and Clinical Immunology, 148(3), 813-821.e7. https://doi.org/10.1016/j.jaci.2021.04.004
Authors:
Liza Konnikova
Tanya O. Robinson
Anna H. Owings
James F. Shirley
Elisabeth Davis
Ying Tang
Sarah Wall
Jian Li
Mohammad H. Hasan
Raad Z. Gharaibeh
Lybil B. Mendoza Alvarez
Lisa K. Ryan
Andria Doty
Jack F. Chovanec
Michael P. O'Connell
Dianne E. Grunes
William P. Daley
Emeran Mayer
Lin Chang
Julia Liu
Scott B. Snapper
Joshua D. Milner
Sarah C. Glover
Jonathan J. Lyons
Affiliated Authors:
Joshua D. Milner
Columbia Affiliation:
Subjects:
Gastrointestinal Diseases (MeSH)
Genetic Diseases, Inborn (MeSH)
Immunoglobulin G (MeSH)
Intestine, Small (MeSH)
Mastocytosis (MeSH)
Tryptases (MeSH)
Author Keywords:
cytof
mast cells
double-negative t cells
hereditary alpha-tryptasemia
mast cell activation
memory b cells
pyroptosis
small intestine
Grants:
R21TR002639 (NIH – National Center for Advancing Translational Sciences)
ZIAAI001192 (NIH – National Institute of Allergy and Infectious Diseases)
Publication Type:
Article
Unique ID:
10.1016/j.jaci.2021.04.004
PMID:
33865872
DOI:
10.1016/j.jaci.2021.04.004
Journal:
Journal of Allergy and Clinical Immunology
Publication Date:
Data Source:
Scopus
Source Link:
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Severe acute respiratory syndrome coronavirus 2 serology levels in pregnant women and their neonates

Kubiak, J. M., Murphy, E. A., Yee, J., Cagino, K. A., Friedlander, R. L., Glynn, S. M., Matthews, K. C., Jurkiewicz, M., Sukhu, A. C., Zhao, Z., Prabhu, M., Riley, L. E., & Yang, Y. J. (2021). Severe acute respiratory syndrome coronavirus 2 serology levels in pregnant women and their neonates. American Journal of Obstetrics and Gynecology, 225(1), 73.e1-73.e7. https://doi.org/10.1016/j.ajog.2021.01.016
Authors:
Jeffrey M. Kubiak
Elisabeth A. Murphy
Jim Yee
Kristen A. Cagino
Rachel L. Friedlander
Shannon M. Glynn
Kathy C. Matthews
Magdalena Jurkiewicz
Ashley C. Sukhu
Zhen Zhao
Malavika Prabhu
Laura E. Riley
Yawei J. Yang
Affiliated Authors:
Jeffrey M. Kubiak
Jim Yee
Kristen A. Cagino
Magdalena Jurkiewicz
Zhen Zhao
Yawei J. Yang
Columbia Affiliation:
Subjects:
Impact of COVID-19 Infection on Pregnancy Outcomes (OpenAlex Topic)
Effects of Medication on Pregnancy Outcomes (OpenAlex Topic)
Pathophysiology and Management of Preeclampsia (OpenAlex Topic)
COVID-19 (MeSH)
Immunoglobulin G (MeSH)
Immunoglobulin M (MeSH)
SARS-CoV-2 (MeSH)
Author Keywords:
covid-19 infection
antibody levels
asymptomatic infection
baby
convalescent infection
cord blood
mother
mother-baby dyads
passive immunity
predictor
prevalence
symptomatic infection
time course
Publication Type:
Article
Unique ID:
10.1016/j.ajog.2021.01.016
PMID:
33497654
DOI:
10.1016/j.ajog.2021.01.016
Journal:
American Journal of Obstetrics and Gynecology
Publication Date:
Data Source:
Scopus
Source Link:
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Phase I Study of the CD47 Blocker TTI-621 in Patients with Relapsed or Refractory Hematologic Malignancies

Ansell, S. M., Maris, M. B., Lesokhin, A. M., Chen, R. W., Flinn, I. W., Sawas, A., Minden, M. D., Villa, D., Percival, M.-E. M., Advani, A. S., Foran, J. M., Horwitz, S. M., Mei, M. G., Zain, J., Savage, K. J., Querfeld, C., Akilov, O. E., Johnson, L. D. S., Catalano, T., … O’Connor, O. A. (2021). Phase I Study of the CD47 Blocker TTI-621 in Patients with Relapsed or Refractory Hematologic Malignancies. Clinical Cancer Research, 27(8), 2190–2199. https://doi.org/10.1158/1078-0432.ccr-20-3706
Authors:
Stephen M. Ansell
Michael B. Maris
Alexander M. Lesokhin
Steven M. Horwitz
Robert W. Chen
Matthew G. Mei
Jasmine Zain
Christiane Querfeld
Ian W. Flinn
Ahmed Sawas
Mark D. Minden
Diego Villa
Kerry J. Savage
Mary-Elizabeth M. Percival
Anjali S. Advani
James M. Foran
Oleg E. Akilov
Lisa D. S. Johnson
Tina Catalano
Penka S. Petrova
Robert A. Uger
Eric L. Sievers
Anca Milea
Kathleen Roberge
Yaping Shou
Owen A. O'Connor
Affiliated Authors:
Ahmed Sawas
Columbia Affiliation:
Subjects:
Mechanisms of Apoptotic Cell Clearance and Immune Regulation (OpenAlex Topic)
Genomic Aberrations and Treatment of Chronic Lymphocytic Leukemia (OpenAlex Topic)
Chimeric Antigen Receptor T Cell Therapy (OpenAlex Topic)
CD47 Antigen (MeSH)
Hematologic Neoplasms (MeSH)
Immune Checkpoint Inhibitors (MeSH)
Immunoglobulin G (MeSH)
Neoplasm Recurrence, Local (MeSH)
Grants:
P50CA097274 (NIH – National Cancer Institute)
Publication Type:
Article
Unique ID:
10.1158/1078-0432.CCR-20-3706
PMID:
33451977
DOI:
10.1158/1078-0432.CCR-20-3706
Journal:
Clinical Cancer Research
Publication Date:
Data Source:
Web of Science
Source Link:
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α-Gal specific-IgE prevalence and levels in Ecuador and Kenya: Relation to diet, parasites, and IgG4

Wilson, J. M., Keshavarz, B., James, H. R., Retterer, M. K. C., Schuyler, A. J., Knoedler, A., Workman, L. J., Ng’ang’a, L., Chico, M. E., Rönmark, E., Heymann, P. W., Perzanowski, M. S., Platts-Mills, T. A. E., & Cooper, P. J. (2021). α-Gal specific-IgE prevalence and levels in Ecuador and Kenya: Relation to diet, parasites, and IgG4. Journal of Allergy and Clinical Immunology, 147(4), 1393-1401.e7. https://doi.org/10.1016/j.jaci.2020.12.650
Authors:
Jeffrey M. Wilson
Behnam Keshavarz
Hayley R. James
Maya K. C. Retterer
Alexander J. Schuyler
Alice Knoedler
Lisa J. Workman
Peter W. Heymann
Thomas A. E. Platts-Mills
Lucy Ng'ang'a
Martha E. Chico
Philip J. Cooper
Eva Ronmark
Matthew S. Perzanowski
Affiliated Authors:
Matthew S. Perzanowski
Columbia Affiliation:
Subjects:
Disaccharides (MeSH)
Food Hypersensitivity (MeSH)
Immunoglobulin E (MeSH)
Immunoglobulin G (MeSH)
Author Keywords:
ascaris
ige
alpha-gal
mammalian meat allergy
parasite
sensitization
Grants:
R37AI020565 (NIH – National Institute of Allergy and Infectious Diseases)
P30ES009089 (NIH – National Institute of Environmental Health Sciences)
Publication Type:
Article
Unique ID:
10.1016/j.jaci.2020.12.650
PMID:
33539899
DOI:
10.1016/j.jaci.2020.12.650
Journal:
Journal of Allergy and Clinical Immunology
Publication Date:
Data Source:
Web of Science
Source Link:
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Antibodies to Low-Copy Number RBC Alloantigen Convert a Tolerogenic Stimulus to an Immunogenic Stimulus in Mice

Jash, A., Usaneerungrueng, C., Howie, H. L., Qiu, A., Luckey, C. J., Zimring, J. C., & Hudson, K. E. (2021). Antibodies to Low-Copy Number RBC Alloantigen Convert a Tolerogenic Stimulus to an Immunogenic Stimulus in Mice. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.629608
Authors:
Arijita Jash
Chomkan Usaneerungrueng
Heather L Howie
Annie Qiu
Chance John Luckey
James C Zimring
Krystalyn E Hudson
Affiliated Authors:
Annie Qiu
Krystalyn E Hudson
Columbia Affiliation:
Subjects:
Diseases Related to Blood Group Variants (OpenAlex Topic)
Mechanosensitive Ion Channels in Physiology and Disease (OpenAlex Topic)
Effects of Blood Transfusion in Clinical Practice (OpenAlex Topic)
Erythrocyte Transfusion (MeSH)
Erythrocytes (MeSH)
Isoantigens (MeSH)
Gene Dosage (MeSH)
Immune Tolerance (MeSH)
Immunity, Humoral (MeSH)
Immunoglobulin G (MeSH)
Isoantibodies (MeSH)
Author Keywords:
alloantibody
alloimmunization
antibody-mediated enhancement
red blood cell
tolerance
Grants:
P01HL132819 (NIH – National Heart, Lung, and Blood Institute)
R01HL135248 (NIH – National Heart, Lung, and Blood Institute)
Publication Type:
Article
Unique ID:
10.3389/fimmu.2021.629608
PMID:
33777014
DOI:
10.3389/fimmu.2021.629608
Journal:
Frontiers in Immunology
Publication Date:
Data Source:
PubMed
Source Link:
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Experimental evidence of pathogenic role of IgG autoantibodies in IgA nephropathy

Moldoveanu, Z., Suzuki, H., Reily, C., Satake, K., Novak, L., Xu, N., Huang, Z.-Q., Knoppova, B., Khan, A., Hall, S., Yanagawa, H., Brown, R., Winstead, C. J., O’Quinn, D. B., Weinmann, A., Gharavi, A. G., Kiryluk, K., Julian, B. A., Weaver, C. T., … Novak, J. (2021). Experimental evidence of pathogenic role of IgG autoantibodies in IgA nephropathy. Journal of Autoimmunity, 118, 102593. https://doi.org/10.1016/j.jaut.2021.102593
Authors:
Zina Moldoveanu
Hitoshi Suzuki
Colin Reily
Kenji Satake
Lea Novak
Nuo Xu
Zhi-Qiang Huang
Barbora Knoppova
Atlas Khan
Stacy Hall
Hiroyuki Yanagawa
Rhubell Brown
Colleen J. Winstead
Darrell B. O'Quinn
Amy Weinmann
Ali G. Gharavi
Krzysztof Kiryluk
Bruce A. Julian
Casey T. Weaver
Yusuke Suzuki
Jan Novak
Affiliated Authors:
Atlas Khan
Ali G. Gharavi
Krzysztof Kiryluk
Columbia Affiliation:
Subjects:
Autoantibodies (MeSH)
Glomerulonephritis, IGA (MeSH)
Immunoglobulin G (MeSH)
Author Keywords:
iga nephropathy
autoantibody
galactose-deficient iga1
igg
immune complexes
Grants:
R01DK105124 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK082753 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
K01DK106341 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R56DK078244 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK078244 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
Publication Type:
Article
Unique ID:
10.1016/j.jaut.2021.102593
PMID:
33508637
DOI:
10.1016/j.jaut.2021.102593
Journal:
Journal of Autoimmunity
Publication Date:
Data Source:
Scopus
Source Link:
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Record Created:

CSV