Mechanisms of Apoptotic Cell Clearance and Immune Regulation

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Yang, L., Han, Y., Zhang, T., Dong, X., Ge, J., Roy, A., Zhu, J., Lu, T., Jeya Vandana, J., de Silva, N., Robertson, C. C., Xiang, J. Z., Pan, C., Sun, Y., Que, J., Evans, T., Liu, C., Wang, W., Naji, A., … Chen, S. (2024). Human vascularized macrophage-islet organoids to model immune-mediated pancreatic β cell pyroptosis upon viral infection. Cell Stem Cell. https://doi.org/10.1016/j.stem.2024.08.007
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Wu, X., Wang, Z., Shern, T., & Zhang, H. (2024). Efferocytosis assay to quantify the engulfment and acidification of apoptotic cells by macrophages using flow cytometry. STAR Protocols, 5(3), 103215. https://doi.org/10.1016/j.xpro.2024.103215
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Klausz, K., Gehlert, C. L., Krohn, S., Winterberg, D., Lustig, M., Boje, A. S., Besse, L., Besse, A., Driessen, C., Peipp, M., & Gramatzki, M. (2023). P-198 Impact of blocking the CD47 axis on phagocytosis of myeloma cells treated with CD38 antibodies and proteasome inhibitors. Clinical Lymphoma Myeloma and Leukemia, 23, S144–S145. https://doi.org/10.1016/s2152-2650(23)01816-5
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Kang, J., Postigo-Fernandez, J., Kim, K., Zhu, C., Yu, J., Meroni, M., Mayfield, B., Bartolomé, A., Dapito, D. H., Ferrante, A. W., Dongiovanni, P., Valenti, L., Creusot, R. J., & Pajvani, U. B. (2023). Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis. JCI Insight, 8(3). https://doi.org/10.1172/jci.insight.165369
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Shi, J., Wu, X., Wang, Z., Li, F., Meng, Y., Moore, R. M., Cui, J., Xue, C., Croce, K. R., Yurdagul, A., Doench, J. G., Li, W., Zarbalis, K. S., Tabas, I., Yamamoto, A., & Zhang, H. (2022). A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-35604-8
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Li, Y., Wu, Y., Federzoni, E. A., Wang, X., Dharmawan, A., Hu, X., Wang, H., Hawley, R. J., Stevens, S., Sykes, M., & Yang, Y.-G. (2022). CD47 cross-dressing by extracellular vesicles expressing CD47 inhibits phagocytosis without transmitting cell death signals. ELife, 11. CLOCKSS. https://doi.org/10.7554/elife.73677
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Bauer, T., Cho, B. C., Heist, R., Bazhenova, L., Werner, T., Goel, S., Kim, D.-W., Adkins, D., Carvajal, R. D., Alva, A., Eaton, K., Wang, J., Liu, Y., Yan, X., Christensen, J., Neuteboom, S., Chao, R., & Pant, S. (2022). First-in-human phase 1/1b study to evaluate sitravatinib in patients with advanced solid tumors. Investigational New Drugs, 40(5), 990–1000. https://doi.org/10.1007/s10637-022-01274-y
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Schilperoort, M., Ngai, D., & Tabas, I. (2022). Efferocytosis induces a transient burst of glycolysis in macrophages to promote lactate-driven binding and continuing removal of apoptotic cells. Atherosclerosis, 355, 1–2. https://doi.org/10.1016/j.atherosclerosis.2022.06.091
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Sallman, D. A., Al Malki, M. M., Asch, A. S., Wang, E. S., Jurcic, J. G., Bradley, T. J., Flinn, I. W., Pollyea, D. A., Kambhampati, S. N., Tanaka, T. N., Zeidner, J. F., Garcia-Manero, G., Jeyakumar, D., Gu, L., Tan, A., Chao, M., O’Hear, C., Lal, I., Vyas, P., & Daver, N. (2022). S166: MAGROLIMAB IN COMBINATION WITH AZACITIDINE FOR PATIENTS WITH UNTREATED HIGHER-RISK MYELODYSPLASTIC SYNDROMES (HR MDS): 5F9005 PHASE 1B STUDY RESULTS. HemaSphere, 6, 67–68. https://doi.org/10.1097/01.hs9.0000843556.59348.1d
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Mysore, V., Tahir, S., Furuhashi, K., Arora, J., Rosetti, F., Cullere, X., Yazbeck, P., Sekulic, M., Lemieux, M. E., Raychaudhuri, S., Horwitz, B. H., & Mayadas, T. N. (2022). Monocytes transition to macrophages within the inflamed vasculature via monocyte CCR2 and endothelial TNFR2. Journal of Experimental Medicine, 219(5). https://doi.org/10.1084/jem.20210562
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