Neoplastic Stem Cells

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Lu, C., Kang, T., Zhang, J., Yang, K., Liu, Y., Song, K., Lin, Q., Dixit, D., Gimple, R. C., Zhang, Q., Shi, Z., Fan, X., Wu, Q., Li, D., Shan, D., Gao, J., Gu, D., You, H., Li, Y., … Wang, X. (2025). Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-58366-5
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Gao, J., Gu, D., Yang, K., Zhang, J., Lin, Q., Yuan, W., Zhu, X., Dixit, D., Gimple, R. C., You, H., Zhang, Q., Shi, Z., Fan, X., Wu, Q., Lu, C., Cheng, Z., Li, D., Zhao, L., Xue, B., … Wang, X. (2025). Infiltrating plasma cells maintain glioblastoma stem cells through IgG-Tumor binding. Cancer Cell, 43(1), 122-143.e8. https://doi.org/10.1016/j.ccell.2024.12.006
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Lv, D., Dixit, D., Cruz, A. F., Kim, L. J. Y., Duan, L., Xu, X., Wu, Q., Zhong, C., Lu, C., Gersey, Z. C., Gimple, R. C., Xie, Q., Yang, K., Liu, X., Fang, X., Wu, X., Kidwell, R. L., Wang, X., Bao, S., … Rich, J. N. (2024). Metabolic regulation of the glioblastoma stem cell epitranscriptome by malate dehydrogenase 2. Cell Metabolism, 36(11), 2419-2436.e8. https://doi.org/10.1016/j.cmet.2024.09.014
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Elaimy, A. L., El-Derany, M. O., James, J., Wang, Z., Pearson, A. N., Holcomb, E. A., Huber, A. K., Gijón, M., Bell, H. N., Sanghvi, V. R., Frankel, T. L., Su, G. L., Tapper, E. B., Tai, A. W., Ramnath, N., Centonze, C. P., Dobrosotskaya, I., Moeller, J. A., Bryant, A. K., … Green, M. D. (2024). SLC4A11 mediates ammonia import and promotes cancer stemness in hepatocellular carcinoma. JCI Insight, 9(21). https://doi.org/10.1172/jci.insight.184826
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Ngule, C., Shi, R., Ren, X., Jia, H., Oyelami, F., Li, D., Park, Y., Kim, J., Hemati, H., Zhang, Y., Xiong, X., Shinkle, A., Vanderford, N. L., Bachert, S., Zhou, B. P., Wang, J., Song, J., Liu, X., & Yang, J.-M. (2024). NAC1 promotes stemness and regulates myeloid-derived cell status in triple-negative breast cancer. Molecular Cancer, 23(1). https://doi.org/10.1186/s12943-024-02102-y
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Hassan, N., Yi, H., Malik, B., Gaspard-Boulinc, L., Samaraweera, S. E., Casolari, D. A., Seneviratne, J., Balachandran, A., Chew, T., Duly, A., Carter, D. R., Cheung, B. B., Norris, M., Haber, M., Kavallaris, M., Marshall, G. M., Zhang, X. D., Liu, T., Wang, J., … Wang, J. Y. (2024). Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML. Blood, 144(1), 84–98. https://doi.org/10.1182/blood.2024024072
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Li, D., Wang, X., Chen, K., Shan, D., Cui, G., Yuan, W., Lin, Q., Gimple, R. C., Dixit, D., Lu, C., Gu, D., You, H., Gao, J., Li, Y., Kang, T., Yang, J., Yu, H., Song, K., Shi, Z., … Wang, X. (2024). IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages. Cell Death & Differentiation, 31(6), 738–752. https://doi.org/10.1038/s41418-024-01292-8
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Cable, J., Pei, D., Reid, L. M., Wang, X. W., Bhatia, S., Karras, P., Melenhorst, J. J., Grompe, M., Lathia, J. D., Song, E., Kuo, C. J., Zhang, N., White, R. M., Ma, S. K., Ma, L., Chin, Y. R., Shen, M. M., Ng, I. O. L., Kaestner, K. H., … Weissman, I. L. (2021). Cancer stem cells: advances in biology and clinical translation—a Keystone Symposia report. Annals of the New York Academy of Sciences, 1506(1), 142–163. Portico. https://doi.org/10.1111/nyas.14719
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