A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion

Flury, A., Aljayousi, L., Park, H.-J., Khakpour, M., Mechler, J., Aziz, S., McGrath, J. D., Deme, P., Sandberg, C., González Ibáñez, F., Braniff, O., Ngo, T., Smith, S., Velez, M., Ramirez, D. M., Avnon-Klein, D., Murray, J. W., Liu, J., Parent, M., … Ayata, P. (2024). A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion. Neuron. https://doi.org/10.1016/j.neuron.2024.11.018
Authors:
Anna Flury
Leen Aljayousi
Hye-Jin Park
Mohammadparsa Khakpour
Jack Mechler
Siaresh Aziz
Jackson D McGrath
Pragney Deme
Colby Sandberg
Fernando González Ibáñez
Olivia Braniff
Thi Ngo
Simira Smith
Matthew Velez
Denice Moran Ramirez
Dvir Avnon-Klein
John W Murray
Jia Liu
Martin Parent
Susana Mingote
Norman J Haughey
Sebastian Werneburg
Marie-Ève Tremblay
Pinar Ayata
Affiliated Authors:
John W Murray
Columbia Affiliation:
Author Keywords:
alzheimer's disease
dark microglia
integrated stress response
isr
lipid secretion
lipotoxicity
microglia
neurodegeneration
neurotoxic microglia
non-cell-autonomous stress
alzheimer’s disease
elink
Publication Type:
Article
Unique ID:
10.1016/j.neuron.2024.11.018
PMID:
39719704
DOI:
10.1016/j.neuron.2024.11.018
Journal:
Neuron
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created: