Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells

Capdevila, C., Miller, J., Cheng, L., Kornberg, A., George, J. J., Lee, H., Botella, T., Moon, C. S., Murray, J. W., Lam, S., Calderon, R. I., Malagola, E., Whelan, G., Lin, C.-S., Han, A., Wang, T. C., Sims, P. A., & Yan, K. S. (2024). Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells. Cell, 187(12), 3039-3055.e14. https://doi.org/10.1016/j.cell.2024.05.001
Authors:
Claudia Capdevila
Jonathan Miller
Liang Cheng
Adam Kornberg
Joel J George
Hyeonjeong Lee
Theo Botella
Christine S Moon
John W Murray
Stephanie Lam
Ruben I Calderon
Ermanno Malagola
Gary Whelan
Chyuan-Sheng Lin
Arnold Han
Timothy C Wang
Peter A Sims
Kelley S Yan
Affiliated Authors:
Claudia Capdevila
Jonathan Miller
Liang Cheng
Adam Kornberg
Joel J George
Hyeonjeong Lee
Theo Botella
Christine S Moon
John W Murray
Stephanie Lam
Ruben I Calderon
Ermanno Malagola
Gary Whelan
Chyuan-Sheng Lin
Arnold Han
Timothy C Wang
Peter A Sims
Kelley S Yan
Author Keywords:
crypt base columnar cells
fgfbp1
intestinal epithelium
intestinal stem cells
intestinal upper crypt
lgr5
lineage hierarchy
time-resolved fate mapping
tissue regeneration
transit-amplifying cells
Publication Type:
Article
Unique ID:
10.1016/j.cell.2024.05.001
PMID:
Journal:
Publication Date:
Data Source:
PubMed

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