Randomized double-blind personalized N-of-1 clinical trial to test the safety and potential efficacy of TJ-68 for treating muscle cramps in amyotrophic lateral sclerosis (ALS): study protocol for a TJ-68 trial

Mitsumoto, H., Cheung, K., Oskarsson, B., Andrews, H. F., Jang, G. E., Andrews, J. A., Shah, J. S., Fernandes, J. A., McElhiney, M., & Santella, R. M. (2023). Randomized double-blind personalized N-of-1 clinical trial to test the safety and potential efficacy of TJ-68 for treating muscle cramps in amyotrophic lateral sclerosis (ALS): study protocol for a TJ-68 trial. Trials, 24(1). https://doi.org/10.1186/s13063-023-07424-8
Authors:
Hiroshi Mitsumoto
Ken Cheung
Björn Oskarsson
Howard F. Andrews
Grace E. Jang
Jinsy A. Andrews
Jaimin S. Shah
Joseph Americo Fernandes
Martin McElhiney
Regina M. Santella
Affiliated Authors:
Hiroshi Mitsumoto
Ken Cheung
Howard F. Andrews
Grace E. Jang
Jinsy A. Andrews
Martin McElhiney
Regina M. Santella
Columbia Affiliation:
Subjects:
Amyotrophic Lateral Sclerosis (MeSH)
Drugs, Chinese Herbal (MeSH)
Amyotrophic Lateral Sclerosis and Frontotemporal Dementia (OpenAlex Topic)
Pathophysiology of Parkinson's Disease (OpenAlex Topic)
Cholinesterase Inhibitors in Neurodegenerative Diseases (OpenAlex Topic)
Author Keywords:
als
kampo
muscle cramp scale
muscle cramps
n-of-1 trials
personalized clinical trial
randomized controlled study
shakuyakukanzoto
study protocol
tj-68
elink
Publication Type:
Article
Unique ID:
10.1186/s13063-023-07424-8
PMID:
37430314
DOI:
10.1186/s13063-023-07424-8
Journal:
Trials
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View OpenAlex Record
View PubMed Record

Record Created: